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https://www.readbyqxmd.com/read/29161302/characteristics-of-somatic-tinnitus-patients-with-and-without-hyperacusis
#1
Massimo Ralli, Richard J Salvi, Antonio Greco, Rosaria Turchetta, Armando De Virgilio, Giancarlo Altissimi, Giuseppe Attanasio, Giancarlo Cianfrone, Marco de Vincentiis
OBJECTIVE: Determine if somatic tinnitus patients with hyperacusis have different characteristics from those without hyperacusis. PATIENTS AND METHODS: 172 somatic tinnitus patients with (n = 82) and without (n = 90) hyperacusis referred to the Tinnitus Unit of Sapienza University of Rome between June 2012 and June 2016 were compared for demographic characteristics, tinnitus features, self-administered questionnaire scores, nature of somatic modulation and history...
2017: PloS One
https://www.readbyqxmd.com/read/29161295/cardiac-and-renal-dysfunction-is-associated-with-progressive-hearing-loss-in-patients-with-fabry-disease
#2
Maria Köping, Wafaa Shehata-Dieler, Mario Cebulla, Kristen Rak, Daniel Oder, Jonas Müntze, Peter Nordbeck, Christoph Wanner, Rudolf Hagen, Sebastian Schraven
BACKGROUND: Fabry disease (FD) is an X-linked recessive hereditary lysosomal storage disorder which results in the accumulation of globotriaosylceramid (Gb3) in tissues of kidney and heart as well as central and peripheral nervous system. Besides prominent renal and cardiac organ involvement, cochlear symptoms like high-frequency hearing loss and tinnitus are frequently found with yet no comprehensive data available in the literature. OBJECTIVE: To examine hearing loss in patients with FD depending on cardiac and renal function...
2017: PloS One
https://www.readbyqxmd.com/read/29161200/early-placement-of-ventilation-tubes-in-infants-with-cleft-lip-and-palate-a-systematic-review
#3
Mark Felton, Jong Wook Lee, Darius D Balumuka, Jugpal S Arneja, Neil K Chadha
Objective Studies have shown that the majority of cleft lip and palate (CLP) children have middle ear fluid present at the time of lip repair (3-4 months). Despite hearing loss, the majority of children do not undergo ventilation tube treatment if required until the time of palate repair (9-12 months). We aimed to examine the effectiveness and potential complications of early ventilation tube placement prior to palatoplasty in infants with cleft lip and palate. Data Sources Medline (1946-2015), Embase (1980-2015), and EBM Reviews (Cochrane Central Register of Controlled)...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29160511/the-importance-of-audiometric-monitoring-in-patients-with-multidrug-resistant-tuberculosis
#4
Karla Anacleto de Vasconcelos, Silvana Maria Monte Coelho Frota, Antonio Ruffino-Netto, Afrânio Lineu Kritski
INTRODUCTION: A total of 771 cases of multidrug-resistant tuberculosis (MDR-TB) were reported in Brazil in 2014. Treatment of MDR-TB with aminoglycosides can produce serious side effects such as permanent and irreversible hearing loss, which occurs in 5-64% of cases, and severely compromise patient quality of life. The goal of this research was to evaluate auditory and vestibular side effects in patients treated for MDR-TB and to identify associations between these complaints and the type of aminoglycoside used...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29160441/psychosocial-hearing-disadvantage-and-associated-factors-among-construction-workers-in-mato-grosso-brazil
#5
Andréia Cristina Munzlinger Dos Santos, Ageo Mário Cândido da Silva, Gabriela Coelho Pereira de Luccia, Clóvis Botelho, Delma Regina Della Riva
OBJECTIVE: To estimate the prevalence and to analyze the factors associated with self-reported hearing handicap by construction workers in the state of Mato Grosso, Brazil. METHODS: A cross-sectional study was conducted with 866 construction and heavy construction workers. Participants responded to an epidemiological survey subdivided in: identification data, sociodemographic data; lifestyle; work environment characteristics; occupational exposure factors; hearing protection measures; and hearing handicap inventory to quantify the psychosocial consequences of work-related hearing loss...
July 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/29160411/spirometry-in-schoolchildren-for-field-studies-does-testing-on-different-days-change-the-result-of-the-exam
#6
Janaina Cristina Scalco, Rafaela Coelho Minsky, Camila Isabel Santos Schivinski
OBJECTIVE: To analyze if there is variation in the results of spirometry performed by healthy schoolchildren on different days. METHODS: Cross-sectional study with healthy schoolchildren aged 7 to 12 years old, in Florianópolis, Santa Catarina, Southern Brazil. Prepubescent children, non-athletes, born at full term, without cardiorespiratory, rheumatic, musculoskeletal, neurological and visual or hearing deficit were included. The child's health was assessed by a health questionnaire and by the survey International Study of Asthma and Allergies in Childhood...
November 13, 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29160337/can-parenting-practices-predict-externalizing-behavior-problems-among-children-with-hearing-impairment
#7
María J Pino, Rosa A Castillo, Antonio Raya, Javier Herruzo
OBJECTIVE: To identify possible differences in the level of externalizing behavior problems among children with and without hearing impairment and determine whether any relationship exists between this type of problem and parenting practices. METHODS: The Behavior Assessment System for Children was used to evaluate externalizing variables in a sample of 118 boys and girls divided into two matched groups: 59 with hearing disorders and 59 normal-hearing controls. RESULTS: Significant between-group differences were found in hyperactivity, behavioral problems, and externalizing problems, but not in aggression...
November 9, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/29160150/electrocardiogram-screening-in-children-with-congenital-sensorineural-hearing-loss-prevalence-and-follow-up-of-abnormalities
#8
Zainab Farzal, Jonathan Walsh, Faisal I Ahmad, Jason Roberts, Sunita J Ferns, And Carlton J Zdanski
Objective The purpose is to determine the prevalence of electrocardiogram (ECG) abnormalities, including borderline and prolonged QT, among screened children with sensorineural hearing loss (SNHL) and to analyze their subsequent medical workup. Study Design Institutional Review Board-approved case series with chart review. Setting Tertiary academic center. Subjects and Methods Cases from 1996 to 2014 involving pediatric patients (N = 1994) with SNHL were analyzed. Abnormal ECGs were categorized as borderline/prolonged QT or other...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29160113/superficial-siderosis-of-central-nervous-system-with-unknown-cause-report-of-2-cases-and-review-of-the-literature
#9
Hao Chen, Hafiz Khuram Raza, Jia Jing, Xinchun Ye, Zuohui Zhang, Fang Hua, Guiyun Cui
OBJECTIVE: To report 2 cases of superficial siderosis of central nervous system (SS-CNS) and a review of the literature. METHODS: We have analyzed the clinical data and relevant features of two patients with SS-CNS who were presented with ataxia and slurred speech. Both patients undertook blood tests, lumbar puncture, head CT (computer tomography) scans, and brain and spinal cord magnetic resonance (MR) scans. In addition, the first patient also undewent enhanced susceptibility-weighted angiography (ESWAN) and the second patient undertook susceptibility weighted imaging (SWI) scan...
November 21, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29160090/two-consecutive-cases-of-persistent-stapedial-artery-managed-with-a-carbon-dioxide-laser
#10
Shawn M Stevens, Zoe A Walters, Kareem Tawfik, Ravi N Samy
OBJECTIVE: (1) Discuss the presentation and management of persistent stapedial artery (PSA) discovered incidentally during cholesteatoma surgery. (2) Review use of carbon dioxide (CO2) laser for treatment of PSA in the setting of chronic ear disease. PATIENTS: Two consecutive patients with PSA and primary acquired cholesteatoma. INTERVENTION(S): Tympanomastoidectomy using a canal wall reconstruction technique. MAIN OUTCOME MEASURE(S): Surgical healing, collateral damage to surrounding anatomy, and postoperative hearing...
November 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29159795/impact-of-chemotherapy-induced-neurotoxicities-on-adult-cancer-survivors-symptom-burden-and-quality-of-life
#11
Christine Miaskowski, Judy Mastick, Steven M Paul, Gary Abrams, Steven Cheung, Jennifer Henderson Sabes, Kord M Kober, Mark Schumacher, Yvette P Conley, Kimberly Topp, Betty Smoot, Grace Mausisa, Melissa Mazor, Margaret Wallhagen, Jon D Levine
PURPOSE: Limited information is available on the impact of chemotherapy (CTX)-induced neurotoxicity on adult survivors' symptom experience and quality of life (QOL). Purposes were to describe occurrence of hearing loss and tinnitus and evaluate for differences in phenotypic characteristics and measures of sensation, balance, perceived stress, symptom burden, and QOL between survivors who received neurotoxic CTX and did (i.e., neurotoxicity group) and did not (i.e., no neurotoxicity group) develop neurotoxicity...
November 20, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29159459/epg5-related-vici-syndrome-a-primary-defect-of-autophagic-regulation-with-an-emerging-phenotype-overlapping-with-mitochondrial-disorders
#12
Shanti Balasubramaniam, Lisa G Riley, Anand Vasudevan, Mark J Cowley, Velimir Gayevskiy, Carolyn M Sue, Caitlin Edwards, Edward Edkins, Reimar Junckerstorff, C Kiraly-Borri, P Rowe, J Christodoulou
Vici syndrome is a rare, under-recognised, relentlessly progressive congenital multisystem disorder characterised by five principal features of callosal agenesis, cataracts, cardiomyopathy, combined immunodeficiency and oculocutaneous hypopigmentation. In addition, three equally consistent features (profound developmental delay, progressive failure to thrive and acquired microcephaly) are highly supportive of the diagnosis. Since its recognition as a distinct entity in 1988, an extended phenotype with sensorineural hearing loss, skeletal myopathy and variable involvement of virtually any organ system, including the lungs, thyroid, liver and kidneys, have been described...
November 21, 2017: JIMD Reports
https://www.readbyqxmd.com/read/29159054/delayed-access-to-bilateral-input-alters-cortical-organization-in-children-with-asymmetric-hearing
#13
Melissa Jane Polonenko, Blake Croll Papsin, Karen Ann Gordon
Bilateral hearing in early development protects auditory cortices from reorganizing to prefer the better ear. Yet, such protection could be disrupted by mismatched bilateral input in children with asymmetric hearing who require electric stimulation of the auditory nerve from a cochlear implant in their deaf ear and amplified acoustic sound from a hearing aid in their better ear (bimodal hearing). Cortical responses to bimodal stimulation were measured by electroencephalography in 34 bimodal users and 16 age-matched peers with normal hearing, and compared with the same measures previously reported for 28 age-matched bilateral implant users...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29158884/a-mitochondrial-disorder-in-a-middle-age-iranian-patient-report-of-a-rare-case
#14
Mostafa Almasi, Mohammad Reza Motamed, Masoud Mehrpour, Bahram Haghi-Ashtiani, Fahimeh Haji Akhondi, Yalda Nilipour, Seyed-Mohammad Fereshtehnejad
Introduction: Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) can involve multiple systems and cause stroke-like episodes and status epilepticus. Case Presentation: A 48-year-old female with history of early fatigability, migraine-type headaches, and bilateral sensory-neural hearing loss presented 3 episodes of serial seizures. On admission she was affected by Wernicke aphasia and, then, right hemiparesis. Investigations showed elevated arterial lactate and ragged red fibers on muscle biopsy...
July 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/29158880/effect-of-mild-cognitive-impairment-and-alzheimer-disease-on-auditory-steady-state-responses
#15
Elaheh Shahmiri, Zahra Jafari, Maryam Noroozian, Azadeh Zendehbad, Hassan Haddadzadeh Niri, Ali Yoonessi
Introduction: Mild Cognitive Impairment (MCI), a disorder of the elderly people, is difficult to diagnose and often progresses to Alzheimer Disease (AD). Temporal region is one of the initial areas, which gets impaired in the early stage of AD. Therefore, auditory cortical evoked potential could be a valuable neuromarker for detecting MCI and AD. Methods: In this study, the thresholds of Auditory Steady-State Response (ASSR) to 40 Hz and 80 Hz were compared between Alzheimer Disease (AD), MCI, and control groups...
July 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/29158869/otitis-media-with-effusion-and-atopy-is-there-a-causal-relationship
#16
REVIEW
Mario E Zernotti, Ruby Pawankar, Ignacio Ansotegui, Hector Badellino, Juan Sebastian Croce, Elham Hossny, Motohiro Ebisawa, Nelson Rosario, Mario Sanchez Borges, Yuan Zhang, Luo Zhang
Otitis Media with Effusion (OME) is an inflammatory condition of the middle ear cleft, acute or chronic, with collection of fluid in the middle ear with an intact tympanic membrane. It is a very common disease in childhood, the most frequent cause of hearing loss in childhood and often requiring surgery. OME is called chronic when the fluid in the middle ear persists for more than three months or when the episodes recur six or more times in one year. The current article covers various aspects of OME including definition, epidemiology...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/29158175/changes-in-gray-and-white-matter-in-subgroups-within-the-tinnitus-population
#17
Sara A Schmidt, Benjamin Zimmerman, Richard O Bido Medina, Jake R Carpenter-Thompson, Fatima T Husain
In this study, we investigated gray and white matter changes in subgroups within the larger tinnitus population related to differences in severity or duration of tinnitus symptoms. Tinnitus is the illusory perception of sound in the absence of an external source, most often experienced as a chronic condition. The psychological reaction to the sound constitutes the severity, or degree of discomfort experienced, and the duration refers to the time since onset of chronic tinnitus. We used voxel- and surface-based morphometry to investigate gray matter changes and diffusion tensor imaging (using fractional anisotropy, or FA, metrics) to assess changes in orientation of white matter tracts, using both whole brain and region of interest analyses...
November 17, 2017: Brain Research
https://www.readbyqxmd.com/read/29158168/identification-and-functional-analysis-of-a-novel-mutation-in-the-pax3-gene-associated-with-waardenburg-syndrome-type-i
#18
Zhijie Niu, Jiada Li, Fen Tang, Jie Sun, Xueping Wang, Lu Jiang, Lingyun Mei, Hongsheng Chen, Yalan Liu, Xinzhang Cai, Yong Feng, Chufeng He
Waardenburg syndrome type 1 (WS1) is a rare autosomal dominant genetic disorder of neural crest cells (NCC) characterized by congenital sensorineural hearing loss, dystopia canthorum, and abnormal iris pigmentation. WS1 is due to loss-of-function mutations in paired box gene 3 (PAX3). Here, we identified a novel PAX3 mutation (c.808C>G, p.R270G) in a three-generation Chinese family with WS1, and then analyzed its in vitro activities. The R270G PAX3 retained nuclear distribution and normal DNA-binding ability; however, it failed to activate MITF promoter, suggesting that haploinsufficiency may be the underlying mechanism for the mild WS1 phenotype of the study family...
November 17, 2017: Gene
https://www.readbyqxmd.com/read/29157806/trigonelline-promotes-auditory-function-through-nerve-growth-factor-signaling-on-diabetic-animal-models
#19
Rodrigo Castañeda, Isabel Rodriguez, Youn Hee Nam, Bin Na Hong, Tong Ho Kang
BACKGROUND: Protection of cochlear function and reconstruction of neuronal networks in damaged auditory sensory structures is crucial for therapeutic treatment of diabetic hearing loss. Nerve growth factor (NGF) has been used as a novel therapeutic target to protect against the neurodegenerative effects of Diabetes Mellitus (DM). PURPOSE: We aimed to evaluate the potential effect of trigonelline (TRG) on reducing auditory damage produced by DM using NGF as a potential marker...
December 1, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29157625/pediatric-type-1-cartilage-tympanoplasty-outcomes-a-comparison-of-short-and-long-term-hearing-results
#20
Isa Kaya, Murat Benzer, Sercan Gode, Furkan Sahin, Cem Bilgen, Tayfun Kirazli
OBJECTIVE: Tympanoplasty is a commonly used procedure in children as in adults. The purposes of this study were to evaluate and report the long term results of type 1 cartilage tympanoplasty in pediatric population. Short term and long term hearing outcomes were compared according to age and perforation location. METHODS: We retrospectively evaluated a total of 76 of 93 patients who had regularly come to visits (38 male and 38 female) with chronic otitis media (COM) and who were younger than 16 years (range, 9-16 years) and underwent a primary type 1 tympanoplasty in tertiary medical center...
November 17, 2017: Auris, Nasus, Larynx
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