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https://www.readbyqxmd.com/read/29341061/pericardial-effusion-unrelated-to-surgery-is-a-predictor-of-mortality-in-heart-transplant-patients
#1
Simon F Stämpfli, Tardu Özkartal, Niels Hagenbuch, Stephan Bernhart, Andreas J Flammer, Alessandra Vecchiati, Georg M Fröhlich, Frank Ruschitzka, Leonhard Held, Felix C Tanner
BACKGROUND: Hemodynamically irrelevant pericardial effusion (PeEf) is a predictor of adverse outcome in heart failure patients. The clinical relevance of a PeEf unrelated to surgery in heart transplant patients remains unknown. This study assesses the prognostic value of PeEf occurring later than one year after transplantation. METHODS: All patients undergoing heart transplantation in Zurich between 1989 and 2012 were screened. Cox proportional hazard models were used to analyse mortality (primary) and hospitalization (secondary endpoint)...
January 17, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29337400/immunization-in-end-stage-renal-disease-the-perception-of-waiting-list-patients
#2
L F Camargo, A M Lother, M Mazzali, R S B Stucchi
BACKGROUND: The number of patients with chronic kidney disease is increasing worldwide, as well as the number of patients in kidney transplant waiting lists. In order to prevent infections related to immunosuppressive therapy, immunization guidelines for CKD patients before transplantation have been proposed. The aim of the present study was to evaluate adherence to immunization in a cohort of CKD patients in transplant waiting list and their renal replacement therapy clinics. METHODS: CKD patients older than 18 years old, receiving renal replacement therapy longer than12 months and included in kidney transplant waiting list at University of Campinas (Unicamp) were enrolled...
January 16, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29334927/dexmedetomidine-prevents-acute-kidney-injury-after-adult-cardiac-surgery-a-meta-analysis-of-randomized-controlled-trials
#3
Yang Liu, Bo Sheng, Suozhu Wang, Feiping Lu, Jie Zhen, Wei Chen
BACKGROUND: Dexmedetomidine has been shown to confer direct renoprotection by stabilizing the sympathetic system, exerting anti-inflammatory effects and attenuating ischemia/reperfusion (I/R) injury in preclinical studies. Results from clinical trials of dexmedetomidine on acute kidney injury (AKI) following adult cardiac surgery are controversial. METHODS: We searched EMBASE, PubMed, and Cochrane CENTRAL databases for randomized controlled trials (RCTs) comparing the renal effect of dexmedetomidine versus placebo or other anesthetic drugs in adult patients undergoing cardiac surgery...
January 15, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29334912/estimating-the-total-prevalence-and-incidence-of-end-stage-kidney-disease-among-aboriginal-and-non-aboriginal-populations-in-the-northern-territory-of-australia-using-multiple-data-sources
#4
Lin Li, Steven Guthridge, Shu Qin Li, Yuejen Zhao, Paul Lawton, Alan Cass
BACKGROUND: Most estimates for End Stage Kidney Disease (ESKD) prevalence and incidence are based on renal replacement therapy (RRT) registers. However, not all people with ESKD will commence RRT and estimates based only on RRT registry data will underestimate the true burden of ESKD in the community. This study estimates the total number of Northern Territory (NT) residents with ESKD including: those receiving RRT, those diagnosed but not receiving RRT and an estimate of "undiagnosed" cases...
January 15, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29333883/simultaneous-intestinal-and-kidney-transplantation-in-adults
#5
Irum Amin, Charlotte Rutter, Adam Barlow, Neil K Russell, J Andrew Bradley, Andrew Jackson, Andrew J Butler
AIM OF THE STUDY: Intestinal transplantation (IT) is a life-saving procedure for carefully selected patients with intestinal failure. We evaluated patients who had undergone simultaneous intestinal and kidney transplantation (SIKT) to determine whether UK guidelines for inclusion of a renal allograft (dialysis dependent or estimated glomerular filtration rate ((eGFR)) < 45 ml/min/1.73 m2) are justified. METHODS: A single centre analysis was undertaken of adults undergoing IT at the Cambridge Transplant Centre between December 2007 and January 2016...
January 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29324940/risk-for-acute-kidney-injury-in-primary-health-care
#6
Maria Célia Laranjeira Rigonatto, Marcia Cristina da Silva Magro
OBJECTIVE: To identify hypertensive and diabetic patients at risk for developing acute kidney injury in the primary health care setting. METHOD: Observational, longitudinal, prospective study. Sample of 56 diabetic and hypertensive individuals. A semi-structured questionnaire was adopted for data collection. For the description of results, were calculated dispersion measures and the Spearman test was used for statistical analysis. The result was considered significant when p <0...
January 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29324500/hydroxyethyl-starch-130-0-4-and-its-impact-on-perioperative-outcome-a-propensity-score-matched-controlled-observation-study
#7
Judith-Irina Pagel, Markus Rehm, Tobias Kammerer, Nikolai Hulde, Eike Speck, Josef Briegel, Falk Reinholz, Alexander Crispin, Klaus F Hofmann-Kiefer
BACKGROUND: Adverse effects of hydroxyethyl starches (HESs) have been verified in patients suffering from sepsis or kidney disease, but not in surgical patients at large. The investigation aimed to determine whether the use of HES 130/0.4 was associated with the incidence of acute postinterventional adverse events compared to Ringer's acetate alone in a perioperative setting. METHODS: This propensity score matched, controlled observational study was performed in a single-centre university hospital...
January 9, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29319880/competing-risks-of-fracture-and-death-in-older-adults-with-chronic-kidney-disease
#8
Rasheeda K Hall, Richard Sloane, Carl Pieper, Courtney Van Houtven, Joanne LaFleur, Robert Adler, Cathleen Colón-Emeric
OBJECTIVES: To examine whether chronic kidney disease (CKD) at any stage is associated with fracture risk after adjusting for competing mortality and to determine whether age or race modify the relationship between CKD and fracture risk. DESIGN: Prospective cohort study. SETTING: Department of Veterans Affairs (VA) national healthcare system. PARTICIPANTS: Men receiving VA primary care aged 65 and older with no history of fracture or osteoporosis therapy (N = 712, 918)...
January 10, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29303902/rhabdomyolysis-in-a-tertiary-picu-a-10-year-study
#9
Ben Gelbart, Renata DeMarco, Alexander David Hussey, Siva P Namachivayam, Rosemary McRae, Catherine Quinlan, Trevor Duke
OBJECTIVES: Rhabdomyolysis is a disorder of muscle breakdown. The aim of this study was to describe the epidemiology of rhabdomyolysis in children admitted to a PICU and to assess the relationship between peak creatinine kinase and mortality. DESIGN: Retrospective cohort study in children admitted to the PICU with rhabdomyolysis between January 1, 2005, and December 31, 2014. Demographic, clinical, and outcome data were recorded. Outcomes were analyzed by level of peak creatinine kinase value (0-10,000, 10,001-50,000, > 50,000IU/L)...
January 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29295829/medication-therapy-management-after-hospitalization-in-ckd-a-randomized-clinical-trial
#10
Katherine R Tuttle, Radica Z Alicic, Robert A Short, Joshua J Neumiller, Brian J Gates, Kenn B Daratha, Celestina Barbosa-Leiker, Sterling M McPherson, Naomi S Chaytor, Brad P Dieter, Stephen M Setter, Cynthia F Corbett
BACKGROUND AND OBJECTIVES: CKD is characterized by remarkably high hospitalization and readmission rates. Our study aim was to test a medication therapy management intervention to reduce subsequent acute care utilization. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The CKD Medication Intervention Trial was a single-blind (investigators), randomized clinical trial conducted at Providence Health Care in Spokane, Washington. Patients with CKD stages 3-5 not treated by dialysis who were hospitalized for acute illness were recruited...
January 2, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29288982/c-terminal-and-intact-fgf23-in-critical-illness-and-their-associations-with-acute-kidney-injury-and-in-hospital-mortality
#11
Karolina Rygasiewicz, Tomasz Hryszko, Andrzej Siemiatkowski, Szymon Brzosko, Alicja Rydzewska-Rosolowska, Beata Naumnik
BACKGROUND: FGF23 proved its value in prognostication of cardiovascular events and mortality among renal patients and general population. Limited data exist whether FGF23 may have any use in prediction of negative outcomes among critically ill patients admitted to intensive care unit (ICU). METHODS: Single center cohort study performed among patients admitted to ICU. The primary exposure was FGF23 plasma concentration measured within 24 h of ICU admission. The primary outcome was incident Acute Kidney Injury (AKI) and in-hospital mortality during the ICU stay...
December 27, 2017: Cytokine
https://www.readbyqxmd.com/read/29288260/effectiveness-of-diabetes-foot-screening-in-primary-care-in-preventing-lower-extremity-amputations
#12
Gary Y Ang, Chun Wei Yap, Nakul Saxena
INTRODUCTION: The risk of lower extremity amputations (LEAs) in diabetics is 20 times higher than in non-diabetics. Clinical practice guidelines recommend that all diabetics should receive an annual foot examination to identify high-risk foot conditions. Despite this recommendation, there is little evidence in the literature to show its effectiveness in preventing LEA. This study aims to evaluate the effectiveness of diabetes foot screening in primary care in preventing LEA and to identify LEA risk factors...
November 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29285942/-non-alcoholic-fatty-liver-disease-as-a-component-of-the-metabolic-syndrome-and-its-causal-correlations-with-other-extrahepatic-diseases
#13
Tamás Halmos, Ilona Suba
Non-alcoholic fatty liver disease is the most common non-infectious chronic liver-disease in our age, and is a spectrum of all the diseases associated with increased fat accumulation in the hepatocytes. Its development is promoted by sedentary life-style, over-feeding, and certain genetic predisposition. Prevalence in the adult population, even in Hungary is ~30%. In a part of cases, this disease may pass into non-alcoholic steatohepatitis, later into fibrosis, rarely into primary hepatocellular cancer. Fatty liver is closely and bidirectionally related to the metabolic syndrome and type 2 diabetes, and nowadays there is a general consensus that fatty liver is the hepatic manifestation of the metabolic sycndrome...
December 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29285424/maturation-of-arteriovenous-fistula-analysis-of-key-factors
#14
REVIEW
Muhammad A Siddiqui, Suhel Ashraff, Thomas Carline
The growing proportion of individuals suffering from chronic kidney disease has considerable repercussions for both kidney specialists and primary care. Progressive and permanent renal failure is most frequently treated with hemodialysis. The efficiency of hemodialysis treatment relies on the functional status of vascular access. Determining the type of vascular access has prime significance for maximizing successful maturation of a fistula and avoiding surgical revision. Despite the frequency of arteriovenous fistula procedures, there are no consistent criteria applied before creation of arteriovenous fistulae...
December 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/29285364/bilateral-and-multiple-mixed-epithelial-and-stromal-tumors-of-the-kidney-a-case-report
#15
Ryo Minoda, Toshio Takagi, Naohiro Toda, Hiroko Itagaki, Tsunenori Kondo, Hideki Ishida, Yoji Nagashima, Kazunari Tanabe
Mixed epithelial and stromal tumor (MEST) of the kidney is a benign tumor occurring predominantly in older women. Histologically, MEST comprises tubuloglandular and cystic structures in an ovarian-like stroma. Bilateral and multiple cases are rare. We herein present a case of bilateral and multiple MEST in a 43-year-old woman. The patient presented with gross hematuria and was referred to a primary care physician. A computed tomography scan revealed 5 tumors in the right and 2 in the left kidney. Renal cell carcinoma was suspected, and left partial nephrectomy followed by right radical nephrectomy was planned...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29282900/barriers-to-effective-case-management-for-disabled-patients-on-hemodialysis
#16
Hidehiro Sugisawa, Yumiko Shimizu, Tamaki Kumagai, Hiroaki Sugisaki, Seiji Ohira, Toshio Shinoda
The present study examined the performance level and its related factors on the process of case management for disabled patients on hemodialysis. Case management performance was evaluated at three stages: patient assessment, making a care plan, and monitoring/evaluation. Candidates for targeting the factors relating to performance included four dimensions: nursing care level, physical malfunction, cognitive malfunction, and barriers to service were used as patient factors; the period of case management for the patient and the knowledge of dialysis emerged as case manager factors; work load was included as an organizational factor; and community resources for these services and communication with surrounding persons were included as system factors...
December 28, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29279634/role-of-urinary-neutrophil-gelatinase-associated-lipocalin-as-a-biomarker-of-acute-kidney-injury-in-patients-with-circulatory-shock
#17
Radhey Shyam, Munna Lal Patel, Rekha Sachan, Satish Kumar, Durgesh Kumar Pushkar
Background: The early prediction of acute kidney injury (AKI) by the current clinical and laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a promising noninvasive biomarker of kidney injury in shock. The aim of this study was to assess the ability of urinary NGAL (uNGAL) to predict AKI in adult Intensive Care Unit (ICU) patients. Materials and Methods: We prospectively studied 70 patients with circulatory shock admitted to the ICU over a period of 1 year...
November 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29262289/excess-clinical-comorbidity-among-hiv-infected-patients-accessing-primary-care-in-us-community-health-centers
#18
Kenneth H Mayer, Stephanie Loo, Phillip M Crawford, Heidi M Crane, Michael Leo, Paul DenOuden, Magda Houlberg, Mark Schmidt, Thu Quach, Sebastian Ruhs, Meredith Vandermeer, Chris Grasso, Mary Ann McBurnie
OBJECTIVES: As the life expectancy of people infected with human immunodeficiency virus (HIV) infection has increased, the spectrum of illness has evolved. We evaluated whether people living with HIV accessing primary care in US community health centers had higher morbidity compared with HIV-uninfected patients receiving care at the same sites. METHODS: We compared data from electronic health records for 12 837 HIV-infected and 227 012 HIV-uninfected patients to evaluate the relative prevalence of diabetes mellitus, hypertension, chronic kidney disease, dyslipidemia, and malignancies by HIV serostatus...
January 1, 2017: Public Health Reports
https://www.readbyqxmd.com/read/29247554/diabetes-and-chronic-kidney-disease-an-increasingly-common-multi-morbid-disease-in-need-of-a-paradigm-shift-in-care
#19
REVIEW
P H Winocour
Diabetes is considered the commonest cause of end-stage renal disease. The increasing incidence of obesity and an ageing population, together, will lead to a greater number of people with diabetes associated with chronic kidney disease that could either be secondary to diabetic nephropathy or of different aetiology. Ageing and obesity influence approaches to the management of diabetes and accurate assessment of kidney disease. People with diabetes and chronic kidney disease consume a disproportionate component of expenditure on medical care...
December 16, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29247527/high-volume-forced-diuresis-with-matched-hydration-using-the-renalguard-system-to-prevent-contrast-induced-nephropathy-a-meta-analysis-of-randomized-trials
#20
Rahman Shah, Sarah J Wood, Sajjad A Khan, Amina Chaudhry, M Rehan Khan, Mohamed S Morsy
BACKGROUND: Contrast-induced nephropathy (CIN) is a well-recognized complication of coronary angiography that is associated with poor outcomes. Several small randomized controlled trials (RCTs) have recently shown that in patients with chronic kidney disease (CKD), furosemide-induced forced diuresis with matched hydration using the RenalGuard system can prevent its occurrence. However, individual studies have been underpowered and thus cannot show significant differences in major clinical endpoints...
December 16, 2017: Clinical Cardiology
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