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A Rampello, P Papi, G Pompa, A Rampello, A Polimeni, C Di Paolo
OBJECTIVE: The aim of this study was to evaluate functionality and clinical application of a novel immediate device in the treatment of temporomandibular disorders (TMDs). To address the research purpose, authors developed and implemented a randomized control clinical trial. PATIENTS AND METHODS: Eighty patients were enrolled in this study and were randomly divided into two subgroups based on the treatment applied: patient group (PG) and control group (CG). The CG was not subjected to any kind of treatment, even placebo, in order to be able to assess the spontaneous development of the pathology over time...
March 2018: European Review for Medical and Pharmacological Sciences
Lu Xu, Xiaofang Che, Ying Wu, Na Song, Sha Shi, Shuo Wang, Ce Li, Lingyun Zhang, Xinlian Zhang, Xiujuan Qu, Yuee Teng
Neoadjuvant chemotherapy (NAC) is of great importance for patients with triple-negative breast cancer (TNBC) and the achievement of pathological complete response (pCR) to NAC in TNBC patients indicates survival benefits. However, the identification of reliable predictive biomarkers of pCR to NAC in TNBC patients remains an urgent and largely unattended medical issue. In the present study, we evaluated the differentially expressed genes (DEGs) between pCR and non-pCR patients after doxorubicin/cyclophosphamide therapy, followed by paclitaxel pre-operative treatment in 64 TNBC patients recorded in the GSE41998 dataset of Gene Expression Omnibus and identified 118 DEGs...
May 2018: Oncology Reports
Randall Youngman
The study of inorganic glass structure is critically important for basic glass science and especially the commercial development of glasses for a variety of technological uses. One of the best means by which to achieve this understanding is through application of solid-state nuclear magnetic resonance (NMR) spectroscopy, which has a long and interesting history. This technique is element specific, but highly complex, and thus, one of the many inquiries made by non-NMR specialists working in glass science is what type of information and which elements can be studied by this method...
March 22, 2018: Materials
Yu Wu, Baicheng Yao, Caibin Yu, Yunjiang Rao
Graphene has become a bridge across optoelectronics, mechanics, and bio-chemical sensing due to its unique photoelectric characteristics. Moreover, benefiting from its two-dimensional nature, this atomically thick film with full flexibility has been widely incorporated with optical waveguides such as fibers, realizing novel photonic devices including polarizers, lasers, and sensors. Among the graphene-based optical devices, sensor is one of the most important branch, especially for gas sensing, as rapid progress has been made in both sensing structures and devices in recent years...
March 22, 2018: Sensors
Jaein Seo, B Douglas Smith, Elihu Estey, Ernest Voyard, Bernadette O' Donoghue, John F P Bridges
OBJECTIVE: Acute myeloid leukemia (AML) is a progressive blood cancer with few effective treatment options. As part of a patient-focused drug development (PFDD) initiative led by the Leukemia and Lymphoma Society (LLS), we sought to use a community-centered approach to develop and pilot an instrument to measure patient preferences for the benefits and risks of treating AML. METHODS: Instrument development was informed by a literature review, engagement with expert stakeholders (n = 12), engagement with community stakeholders, and pretesting...
March 22, 2018: Current Medical Research and Opinion
Ronald J Maughan, Susan M Shirreffs, Alan Vernec
The use of dietary supplements is widespread among athletes in all sports and at all levels of competition, as it is in the general population. For the athlete training at the limits of what is sustainable, or for those seeking a shortcut to achieving their aims, supplements offer the prospect of bridging the gap between success and failure. Surveys show, however, that this is often not an informed choice and that the knowledge level among consumers is often low and that they are often influenced in their decisions by individuals with an equally inadequate understanding of the issues at stake...
March 22, 2018: International Journal of Sport Nutrition and Exercise Metabolism
Vania Mattoso Ribeiro, Teresa Palmisciano Bede, Gabrielle S Rocha, Sergio Barroso, Samuel Valença, Vilma Blondet de Azeredo
BACKGROUND: High fat diets have been implicated in the generation of reactive oxygen species (ROS). Polyphenols from grapes may reduce ROS and restore oxidative balance. The aim of this study is to investigate the antioxidant properties of high polyphenols beverages associated with a high fat diet in enzymatic and non-enzymatic antioxidant activity. MATERIAL AND METHODS: Fifty female rats were divided into five groups: a) control group (CG) - control diet (4% fat); b) high fat diet group (HFD) - high fat diet (20% fat); c) grape juice group (GJ) - grape juice (15 ml/day) + high fat diet; d) red wine group (RW) - red wine (10 ml/day) + high fat diet; and e) resveratrol solution group (RS) - resveratrol solution (15 ml/day) + high fat diet...
November 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Norma Amador-Licona, Evelin Valeria Moreno-Vargas, Claudia Martinez-Cordero
INTRODUCTION: The daily protein recommendation for adults is 0.8 g/kg/day; however, several studies argue that an intake of 1.0-1.5 g protein/kg/day could benefit the health of the elderly. OBJECTIVE: We evaluated the protein intake and serum lipid levels in elderly patients with hip fracture, determining their correlation with the grip strength in both hands. METHODS: The study included 47 adult patients aged 65-85 years hospitalized for recent hip fracture...
January 10, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Alonso Hormazábal-Peralta, Javier Espinoza, Pablo Cáceres, Pablo A Lizana
OBJECTIVES: Physical activity (PA) has been shown to have multiple health and wellness benefits, but there is no such information for adolescents with high intellectual ability (HIA). Thus, the aim of this study is to assess body composition and PA in HIA Chilean adolescents. METHODS: Weight and body composition were measured by bioelectrical impedance in 73 adolescents (39 female) aged 14-18 years from the Valparaíso region of Chile. HIA was assessed via Raven's Progressive Matrices (> 75th percentile) and PA, via questionnaire...
January 10, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Sara Bermejo de Las Heras, Licia De la Calle de la Rosa, Javier Arias Díaz, Manuel Giner, Antonio Luis Blesa Malpica
BACKGROUND: Malnutrition is particularly prevalent among intensive care unit (ICU) patients, being associated with poor clinical results. Enteral nutrition (EN) offers multiple benefits on critically ill patients and its monitoring was established by the Spanish Society of Critical Care (SEMICYUC) as a clinical quality indicator (CQI; EN patients correctly monitorized / all EN patients, as %). However, no results have been published on its regulated monitoring. OBJECTIVES: Assessing CQI's compliance, identifying difficulties and possibilities for its use...
January 10, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
(no author information available yet)
In the context of the White Book of Physical and Rehabilitation Medicine (PRM) in Europe, this paper describes the background to the context of PRM services and comprises the following: - Epidemiological Aspects of Functioning and Disability - Ethical Aspects and Human Rights - Rehabilitation and Health Systems - Economic Burden of Disability - Effects of Lack of Rehabilitation Health care service planning accounts for the burden of disability among society and the chapter describes the justification for specialist rehabilitation, the background of PRM and why making a functional diagnosis and a management plan based on function is its core competence...
April 2018: European Journal of Physical and Rehabilitation Medicine
Songcheng Wang, Yi Zhang, J Carson Meredith, Sven H Behrens, Manoj Kumar Tripathi, Kirti Chandra Sahu
Air bubbles rising through an aqueous medium have been studied extensively and are routinely used for the separation of particulates via froth flotation, a key step in many industrial processes. Oil-coated bubbles can be more effective for separating hydrophilic particles with low affinity for the air-water interface, but the rise dynamics of oil-coated bubbles has not yet been explored. In the present work, we report the first systematic study of the shape and rise trajectory of bubbles engulfed in a layer of oil...
March 22, 2018: Soft Matter
Tobias Engl, Martin Kaltenpoth
Covering: up to 2018Pheromones serve as chemical signals between individuals of the same species and play important roles for mate localization and mate choice as well as other social interactions in insects. A growing body of literature indicates that microbial symbionts can modulate their hosts' chemical profiles, mate choice decisions and social behavior. This modulation can occur by the direct biosynthesis of pheromone components or the provisioning of precursors, or through general changes in the metabolite pool of the host and its resource allocation into pheromone production...
March 22, 2018: Natural Product Reports
Paolo Cornaglia Ferraris
Humans are influenced by irrational preferences in making choices, so that clinicians also are prone to irrational decision-making. Exhaustive information about the value of therapies are frequently unavailable, full results of intervention trials are often hidden, conclusive evidence is highly desirable but it is seldom accessible. Healthcare could benefit from the new ways of approaching the decision framework due to behavioral economists: understanding the hidden traps in decision-making and the way the human brain works is an essential step and the best protection from biases is always awareness...
March 2018: Recenti Progressi in Medicina
Gregory B Lim
No abstract text is available yet for this article.
March 22, 2018: Nature Reviews. Cardiology
Elpidio Santillo, Monica Migale, Carlo Massini, Raffaele Antonelli Incalzi
BACKGROUND: Levosimendan is a calcium sensitizer drug causing increased contractility in the myocardium and vasodilation in the vascular system. It is mainly used for the therapy of acute decompensated heart failure. Several studies on animals and humans provided evidence of the cardioprotective properties of levosimendan including preconditioning and anti-apoptotic. In view of these favorable effects, levosimendan has been tested in patients undergoing cardiac surgery for the prevention or treatment of low cardiac output syndrome...
March 21, 2018: Current Cardiology Reviews
Judi Mesman
This introduction to the special issue on video observations of sensitive caregiving in different cultural communities provides a general theoretical and methodological framework for the seven empirical studies that are at the heart of this special issue. It highlights the cross-cultural potential of the sensitivity construct, the importance of research on sensitivity "off the beaten track," the advantages and potential challenges of the use of video in diverse cultural contexts, and the benefits of forming research teams that include local scholars...
March 22, 2018: Attachment & Human Development
Kateřina Rusinová, Markéta Červenková, Zuzana Čepelíková, Ondřej Kopecký
Palliative care is an important constituent of widely accepted quality care standard in seriously ill patients. The needs of these patients in perioperative setting or in intensive care are considerable for attending teams. Principal issues discussed include excellent communication skills during decision making before a high-risk surgery, and risk-benefit weighting in order to respect patients values and preferences. This article, based on examples of interventions in both perioperative care and in intensive care units, aims to demonstrate a complex integrated palliative approach...
2018: Casopís Lékar̆ů C̆eských
Martin Gřiva, Jiří Šťastný, Marie Lazárová, Helena Krejčíková
Chronic heart failure is a progressive disease with an increasing prevalence. In spite of all medical progress (or thanks to it), it is finally one of the most common causes of death. Palliative care is an approach aimed to improve the quality of life of patients and their families in cases of life-threatening illness. Therefore, the use of palliative care in cardiology is entirely relevant. Estimating the course and prognosis of a patient with chronic heart failure is difficult despite many prognostic tools...
2018: Casopís Lékar̆ů C̆eských
Ana Cristina Corrêa Figueira, António Cortinhas, Jorge Pinto Soares, José Carlos Leitão, Rita Pinho Ferreira, Jose Alberto Duarte
The use of preclinical models to investigate antitumor effects of exercise on breast tumor (BT) development and progression are critical. However, published results have not been quantitatively summarized or examined for potential exercise-moderating variables. We conducted this review to summarize and quantify the effect-size of exercise on BT outcomes in preclinical studies. A literature search was performed in MEDLINE, PubMed, Web of Science and System for Information on Grey Literature in Europe (SIGLE) databases...
March 21, 2018: International Journal of Sports Medicine
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