Yangnan Hu, Jiayue Xing, Hui Zhang, Xinyi Pang, Yabo Zhai, Hong Cheng, Dongyu Xu, Menghui Liao, Yanru Qi, Danqi Wu, Bin Zhang, Lin Cheng, Bo Chu, Chen Zhang, Yuanjin Zhao, Renjie Chai
Organ-on-chips can highly simulate the complex physiological functions of organs, exhibiting broad application prospects in developmental research, disease simulation, as well as new drug research and development. However, there is still less concern about effectively constructing cochlea-on-chips. Here, a novel cochlear organoids-integrated conductive hydrogel biohybrid system with cochlear implant electroacoustic stimulation (EAS) for cochlea-on-a-chip construction and high-throughput drug screening, is presented...
March 15, 2024: Advanced Materials