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https://www.readbyqxmd.com/read/29339224/emerging-souvenirs-clinical-presentation-of-the-returning-traveller-with-imported-arbovirus-infections-in-europe
#1
Isabella Eckerle, Violeta Briciu, Onder Ergonul, Mihaela Lupse, Anna Papa, Amanda Radulescu, Sotirios Tsiodras, Christine Tsitou, Christian Drosten, Véronique Nussenblatt, Chantal Reusken, Louise Sigfrid, Nick J Beeching
BACKGROUND: Arboviruses are an emerging group of viruses that are causing increasing health concerns globally, including in Europe. Clinical presentation usually consists of a non-specific febrile illness that may be accompanied by rash, arthralgia and arthritis and/or with neurological or haemorrhagic syndromes. The range of differential diagnoses of other infectious and non-infectious aetiologies is broad, presenting a challenge for physicians. While knowledge of the geographic distribution of pathogens and the current epidemiological situation, incubation periods, exposure risk factors and vaccination history can help guide the diagnostic approach, the non-specific and variable clinical presentation can delay final diagnosis...
January 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29329394/analysis-of-the%C3%A2-aedes-albopictus%C3%A2-c6-36-genome-provides-insight-into-cell-line-utility-for-viral-propagation
#2
Jason R Miller, Sergey Koren, Kari A Dilley, Vinita Puri, David M Brown, Derek M Harkins, Françoise Thibaud-Nissen, Benjamin Rosen, Xiao-Guang Chen, Zhijian Tu, Igor V Sharakhov, Maria V Sharakhova, Robert Sebra, Timothy B Stockwell, Nicholas H Bergman, Granger G Sutton, Adam M Phillippy, Peter M Piermarini, Reed S Shabman
Background: The 50-year old Aedes albopictus C6/36 cell line is a resource for the detection, amplification, and analysis of mosquito-borne viruses including Zika, dengue, and chikungunya. The cell line is derived from an unknown number of larvae from an unspecified strain of Aedes albopictus mosquitoes. Toward improved utility of the cell line for research in virus transmission, we present an annotated assembly of the C6/36 genome. Results: The C6/36 genome assembly has the largest contig N50 (3...
January 10, 2018: GigaScience
https://www.readbyqxmd.com/read/29324725/west-nile-virus-and-other-nationally-notifiable-arboviral-diseases-united-states-2016
#3
Alexis Burakoff, Jennifer Lehman, Marc Fischer, J Erin Staples, Nicole P Lindsey
Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes and ticks. West Nile virus (WNV) is the leading cause of domestically acquired arboviral disease in the continental United States (1,2). Other arboviruses, including La Crosse, Powassan, Jamestown Canyon, St. Louis encephalitis, and eastern equine encephalitis viruses, cause sporadic cases of disease and occasional outbreaks. This report summarizes surveillance data reported to CDC for 2016 for nationally notifiable arboviruses...
January 12, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29322519/inactivation-of-chikungunya-virus-in-blood-components-treated-with-amotosalen-ultraviolet-a-light-or-amustaline-glutathione
#4
Andrew Laughhunn, Yan-Jang S Huang, Dana L Vanlandingham, Marion C Lanteri, Adonis Stassinopoulos
BACKGROUND: Chikungunya virus, a mosquito-borne arbovirus, often co-circulates with the Zika, dengue, and yellow fever viruses in Aedes mosquito-infested areas where cases of arbovirus transfusion-transmitted infections have been reported. Building on past experience to help maintain the availability of safe components during major outbreaks of chikungunya virus in La Reunion, Italy, and Thailand and of Zika virus in the Pacific, the Caribbean, and the Americas, pathogen inactivation is a mitigation strategy to reduce the risk of transfusion-transmitted infection...
January 10, 2018: Transfusion
https://www.readbyqxmd.com/read/29314584/qsar-analysis-of-plant-derived-compounds-with-larvicidal-activity-against-zika-aedes-aegypti-diptera-culicidae-vector-using-freely-available-descriptors
#5
Laura M Saavedra, Gustavo P Romanelli, Pablo R Duchowicz
BACKGROUND: We develop a QSAR model for predicting the larvicidal activity of 60 plant-derived molecules against Aedes aegypti L. (Diptera: Culicidae), vector of several diseases such as, dengue, yellow fever, chikungunya and Zika virus. The balanced subsets method (BSM) based on k-means cluster analysis (k-MCA) is employed to split the data set. The replacement method (RM) variable subset selection technique coupled with multivariable linear regression (MLR) proves to be successful for exploring 18,326 molecular descriptors and fingerprints calculated with PaDEL, Mold2 and EPI Suite open-source software...
January 4, 2018: Pest Management Science
https://www.readbyqxmd.com/read/29305550/comparison-of-four-serological-methods-and-two-rt-pcr-assays-for-diagnosis-and-surveillance-of-zika
#6
Angel Balmaseda, Jose Victor Zambrana, Damaris Collado, Nadezna Garcia, Saira Saborío, Douglas Elizondo, Juan Carlos Mercado, Karla Gonzalez, Cristhiam Cerpas, Andrea Nuñez, Davide Corti, Jesse J Waggoner, Guillermina Kuan, Raquel Burger-Calderon, Eva Harris
Zika virus (ZIKV) is a mosquito-borne flavivirus that is responsible for recent explosive epidemics in the Americas. Notably, ZIKV infection during pregnancy has been found to cause congenital birth defects, including microcephaly, and ZIKV has been associated with Guillain Barré Syndrome in adults. Diagnosis and surveillance of Zika in the Americas have been challenging due to similar clinical manifestations and extensive antibody cross-reactivity with endemic flaviviral diseases, like dengue. We evaluated four serological and two RT-PCR methods in acute (mean day 1...
January 5, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29305089/how-do-virus-mosquito-interactions-lead-to-viral-emergence
#7
REVIEW
Claudia Rückert, Gregory D Ebel
Arboviruses such as West Nile, Zika, chikungunya, dengue, and yellow fever viruses have become highly significant global pathogens through unexpected, explosive outbreaks. While the rapid progression and frequency of recent arbovirus outbreaks is associated with long-term changes in human behavior (globalization, urbanization, climate change), there are direct mosquito-virus interactions which drive shifts in host range and alter virus transmission. This review summarizes how virus-mosquito interactions are critical for these viruses to become global pathogens at molecular, physiological, evolutionary, and epidemiological scales...
January 2, 2018: Trends in Parasitology
https://www.readbyqxmd.com/read/29298700/evidence-for-multiple-insecticide-resistance-in-urban-aedes-albopictus-populations-in-southern-china
#8
Yiji Li, Jiabao Xu, Daibin Zhong, Hong Zhang, Wenqiang Yang, Guofa Zhou, Xinghua Su, Yang Wu, Kun Wu, Songwu Cai, Guiyun Yan, Xiao-Guang Chen
BACKGROUND: Aedes albopictus (Skuse) is an invasive mosquito that has become an important vector of chikungunya, dengue and Zika viruses. In the absence of specific antiviral therapy or a vaccine, vector management is the sole method available for reducing Aedes-induced disease morbidity. Determining the resistance status of Ae. albopictus to insecticides and exploring the resistance mechanisms is essential for future vector control planning. METHODS: Aedes albopictus larvae and pupae were sampled from six sites (two sites each from urban, suburban and rural) in Guangzhou...
January 3, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29296705/zika-and-chikungunya-virus-infections-in-hematopoietic-stem-cell-transplant-recipients-and-oncohematological-patients
#9
Clarisse Martins Machado, Bárbara Brito de Souza Pereira, Alvina Clara Felix, Maria Carolina Oliveira, Luiz Guilherme Darrigo, Mair Pedro de Souza, Eduardo José de Alencar Paton, Fabia Neves, Vergilio Rensi Colturato, Belinda Pinto Simoes
Aedes mosquitoes are well adapted in domestic environments and widespread in tropical regions. Since 2015, Brazil has been experiencing a triple epidemic of dengue (DENV), chikungunya (CHKV), and Zika (ZIKV) viruses. The last 2 viruses are likely following the path of DENV, which has been endemic in most parts of the country since the 1980s. Given this triple epidemic, we proposed a prospective and collaborative study to assess the prevalence, morbidity, and mortality of DENV, CHKV, and ZIKV infections in hematopoietic stem cell transplant (HSCT) recipients and oncohematological patients...
April 11, 2017: Blood Advances
https://www.readbyqxmd.com/read/29290037/n-substituted-methyl-maleamates-as-larvicidal-compounds-against-aedes-aegypti-diptera-culicidae
#10
Laura Harburguer, Paula V Gonzalez, Paola Gonzalez Audino, Eduardo Zerba, Héctor Masuh
Severe human arboviral diseases can be transmitted by the mosquito Aedes aegypti (L.), including dengue, chikungunya, zika, and yellow fever. The use of larvicides in containers that can result as potential breeding places and cannot be eliminated is the main alternative in control programs. However, their continuous and widespread use caused an increase in insecticide-resistant populations of this mosquito. The aim of this study was to evaluate the effect of three N-substituted methyl maleamates as larvicides on Ae...
December 30, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29278457/first-evidence-of-resistance-to-pyrethroid-insecticides-in-italian-aedes-albopictus-populations-after-26-years-since-invasion
#11
Verena Pichler, Romeo Bellini, Rodolfo Veronesi, Daniele Arnoldi, Annapaola Rizzoli, Riccardo Paolo Lia, Domenico Otranto, Fabrizio Montarsi, Sara Carlin, Marco Ballardini, Elisa Antognini, Marco Salvemini, Emanuele Brianti, Gabriella Gaglio, Mattia Manica, Pietro Cobre, Paola Serini, Enkelejda Velo, John Vontas, Ilias Kioulos, Joao Pinto, Alessandra Della Torre, Beniamino Caputo
BACKGROUND: Aedes albopictus has spread during the last decades all over the world. This has increased significantly the risk of exotic arbovirus transmission (e.g. Chikungunya, Dengue, and Zika) also in temperate areas, as testified by the Chikungunya 2007- and 2017-outbreaks in north-east and central Italy. Insecticides represent a main tool for limiting the circulation of these mosquito-borne viruses. The aim of the present study is to start filling the current gap of knowledge on pyrethroid insecticide resistance of European Ae...
December 26, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29273403/zika-virus-an-emerging-infectious-disease-with-serious-perinatal-and-neurologic-complications
#12
Thomas B Casale, Michael N Teng, Jamie P Morano, Thomas Unnasch, Charles J Lockwood
Zika virus (ZIKV) is a flavivirus that is primarily transmitted by Aedes aegypti, the mosquito vector also important in the transmission of the flaviviruses responsible for dengue fever, yellow fever and chikungunya. Due to occurrence in the same geographic regions, serological cross-reactivity, and similar, albeit often less severe clinical manifestations as dengue and chikungunya infections, ZIKV infection likely went undetected and/or misdiagnosed for many years. ZIKV is somewhat unique among flaviviruses in its ability to also be transmitted via sexual contact, non-sexual body fluids and perinatally...
December 19, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29261766/characteristics-of-aedes-aegypti-adult-mosquitoes-in-rural-and-urban-areas-of-western-and-coastal-kenya
#13
Bryson Alberto Ndenga, Francis Maluki Mutuku, Harun Njenga Ngugi, Joel Omari Mbakaya, Peter Aswani, Peter Siema Musunzaji, John Vulule, Dunstan Mukoko, Uriel Kitron, Angelle Desiree LaBeaud
Aedes aegypti is the main vector for yellow fever, dengue, chikungunya and Zika viruses. Recent outbreaks of dengue and chikungunya have been reported in Kenya. Presence and abundance of this vector is associated with the risk for the occurrence and transmission of these diseases. This study aimed to characterize the presence and abundance of Ae. aegypti adult mosquitoes from rural and urban sites in western and coastal regions of Kenya. Presence and abundance of Ae. aegypti adult mosquitoes were determined indoors and outdoors in two western (urban Kisumu and rural Chulaimbo) and two coastal (urban Ukunda and rural Msambweni) sites in Kenya...
2017: PloS One
https://www.readbyqxmd.com/read/29260658/origin-of-a-high-latitude-population-of-aedes-aegypti-in-washington-dc
#14
Andrea Gloria-Soria, Andrew Lima, Diane D Lovin, Joanne M Cunningham, David W Severson, Jeffrey R Powell
An overwintering population of Aedes aegypti has been documented in the Capitol Hill neighborhood of Washington, DC, since 2011. Mitochondrial cytochrome oxidase I (mtCOI) sequence data presented in a previous study traced the origin to the New World. Here, we use microsatellite and SNP chip data along with more mitochondrial DNA (mtDNA) sequences on Washington Ae. aegypti samples and samples from potential sources to further narrow the origin of this population. Genetically, Washington Ae. aegypti are closest to populations in Florida, meaning this is the most likely source...
December 18, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29260651/the-epidemiology-of-imported-acute-infectious-diseases-in-zhejiang-province-china-2011-2016-analysis-of-surveillance-data
#15
Zheyuan Ding, Chen Wu, Haocheng Wu, Qinbao Lu, Junfen Lin
To explore epidemiological characteristics of imported acute infectious diseases between 2011 and 2016 in Zhejiang province, China. Data of imported infectious diseases from 2011 to 2016 was collected from the China Information System for Disease Control and Prevention in Zhejiang province, and subsequently analyzed for epidemiological characteristics. A survey was conducted to investigate clinicians' abilities to diagnose these diseases in Zhejiang province. From 2011 to 2016, 1,241 cases of imported acute infectious disease were reported in Zhejiang province, including 1,078 malaria cases, 156 dengue cases, three chikungunya fever cases and four Zika cases...
December 18, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29259764/utility-of-massive-open-online-courses-moocs-concerning-outbreaks-of-emerging-and-reemerging-diseases
#16
Guido Bendezu-Quispe, Junior Smith Torres-Roman, Brenda Salinas-Ochoa, Akram Hernández-Vásquez
The emergence and re-emergence of infectious diseases such as Ebola, chikungunya, and Zika increase the necessity of knowledgeable and skilled health professionals. Massive open online courses (MOOCs) arise as opportunities that allow people around the world to participate in higher education courses. A search was conducted on specialized MOOC platforms to find courses related to outbreaks, using terms included in the list of the WHO disease outbreaks from January 1st to December 31 st, 2016. We found seven courses about Ebola, two about Zika, three about the dynamics of epidemics and pandemics, and only one course about dengue, chikungunya, and malaria...
2017: F1000Research
https://www.readbyqxmd.com/read/29238544/population-genomics-of-the-asian-tiger-mosquito-aedes-albopictus-insights-into-the-recent-worldwide-invasion
#17
Panayiota Kotsakiozi, Joshua B Richardson, Verena Pichler, Guido Favia, Ademir J Martins, Sandra Urbanelli, Peter A Armbruster, Adalgisa Caccone
Aedes albopictus, the "Asian tiger mosquito," is an aggressive biting mosquito native to Asia that has colonized all continents except Antarctica during the last ~30-40 years. The species is of great public health concern as it can transmit at least 26 arboviruses, including dengue, chikungunya, and Zika viruses. In this study, using double-digest Restriction site-Associated DNA (ddRAD) sequencing, we developed a panel of ~58,000 single nucleotide polymorphisms (SNPs) based on 20 worldwide Ae. albopictus populations representing both the invasive and the native range...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29232453/detection-of-zika-virus-in-aedes-mosquitoes-from-mexico
#18
Herón Huerta, Jesús Felipe González-Roldán, Gustavo Sánchez-Tejeda, Fabián Correa-Morales, Francisco Eduardo Romero-Contreras, Raúl Cárdenas-Flores, Mónica Liliana Rangel-Martínez, Juan Manuel Mata-Rivera, José de Jesús Siller-Martínez, Gonzalo M Vazquez-Prokopec, Pablo Manrique-Saide, Felipe Dzul-Manzanilla, Mauricio Vázquez-Pichardo, Claudia Rosales-Jiménez, María de la Luz Torres-Rodríguez, Alma Núñez-León, Belem Torres-Longoria, Irma López-Martínez, Cuitláhuac Ruíz-Matus, Pablo Antonio Kuri-Morales, José Alberto Díaz-Quiñónez
Background: We report on the results of an entomovirological surveillance system of Aedes populations performed by the Ministry of Health of the central state of San Luis Potosí, Mexico. Methods: Indoor adult Aedes aegypti and Aedes albopictus pools collected at San Martín, Tamazunchale, Ciudad Valles, Metlapa, Ebano, Tamuin and Axtla during the dry season of 2016 were examined for the presence of dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV) viruses using real-time PCR...
July 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29228413/estimating-vector-borne-viral-infections-in-the-urban-setting-of-the-2020-tokyo-olympics-japan-using-mathematical-modeling
#19
Hiroyuki Furuya
The first domestic outbreak of dengue fever in Japan since 1945 was reported in Tokyo in 2014. Meanwhile, daily mean summer temperatures are expected to continue to rise world-wide. Such conditions are expected to increase the risk of an arbovirus outbreak at the 2020 Tokyo Olympic Games. To address this possibility, the present study compared estimates of the risk of infection by dengue, chikungunya, and Zika viruses in urban areas. To compare the risk of infection by arboviruses transmitted by Ae. albopictus mosquitoes, the reproduction number for each of three arboviruses was estimated under the environmental conditions associated with the 2014 dengue outbreak in Tokyo, and additionally under conditions assuming a daily mean temperature elevation of 2° C...
December 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/29228197/efficacy-of-13-commercial-household-aerosol-insecticides-against-aedes-aegypti-diptera-culicidae-from-morelos-mexico
#20
Pablo A Kuri-Morales, Fabián Correa-Morales, Cassandra González-Acosta, Miguel Moreno-Garcia, Eduardo Dávalos-Becerril, José Ismael Benitez-Alva, Jorge Peralta-Rodriguez, Victor Salazar-Bueyes, Jesús F González-Roldán
In Mexico, Aedes aegypti (L.) (Diptera: Culicidae) is the primary vector of Dengue, Zika, and Chikungunya viruses. Control programs include community participation using personal protection such as household aerosol insecticides. In both, urban or rural areas, the use of aerosol insecticides is a common practice to avoiding mosquito biting. Thus, information on the efficacy of commercial products must be available. This study reports the efficacy of 13 household aerosol insecticides against Ae. aegypti from an endemic dengue area in Mexico...
December 8, 2017: Journal of Medical Entomology
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