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Formulary management

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https://www.readbyqxmd.com/read/29222365/implementation-of-an-integrated-pharmacy-supply-management-strategy
#1
Lindsey B Amerine, Daniel R Calvert, Ashley L Pappas, Sarah M Lee, John M Valgus, Scott W Savage
PURPOSE: Implementation of an integrated pharmacy supply management strategy is described. SUMMARY: In 2011, the formulary approval process and supply management for oncology medications were independent of each other at an oncology infusion center. Numerous nonformulary medications were kept on hand and reordered based on inventory levels that were established with inadequate usage information, while some formulary agents did not have on-hand inventory levels and had to be reordered on a patient-specific basis, which required paperwork and then a review by drug information staff per institutional policy...
December 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29216018/impact-of-a-graduated-approach-on-opioid-initiation-and-loss-of-earnings-following-workplace-injury-a-time-series-analysis
#2
Tara Gomes, June Duesburry, Marc-Erick Theriault, Donna Bain, Samantha Singh, Diana Martins, David N Juurlink
OBJECTIVE: The aim of this study was to explore the impact of the Ontario Workplace Safety and Insurance Board's (WSIB's) graduated approach to opioid management on opioid prescribing and disability claim duration. METHODS: We studied patterns of opioid use and disability claim duration among Ontarians who received benefits through the WSIB between 2002 and 2013. We used interventional time series analysis to assess the impact of the WSIB graduated formulary on these trends...
December 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29214053/severe-carvedilol-toxicity-without-overdose-caution-in-cirrhosis
#3
Satish Maharaj, Karan Seegobin, Julio Perez-Downes, Belinda Bajric, Simone Chang, Pramod Reddy
Background: Carvedilol is used in the management of hypertension, ischemic heart disease, heart failure and most recently, portal hypertension. It has been associated with improved outcomes regarding variceal bleeding, hepatic decompensation and death when compared to propranolol and endoscopic band ligation. The main cause of portal hypertension is cirrhosis and therefore carvedilol is increasingly used in these patients. Due to its extensive hepatic metabolism, carvedilol is contraindicated in severe hepatic impairment...
2017: Clinical Hypertension
https://www.readbyqxmd.com/read/29185196/acmt-position-statement-addressing-the-rising-cost-of-prescription-antidotes
#4
Maryann Mazer-Amirshahi, Andrew Stolbach, Lewis S Nelson
Antidotal therapy is an essential component of poisoning management. In recent years, there have been unprecedented increases in the costs of antidotes. The American College of Medical Toxicology calls upon providers, hospitals, formularies pharmaceutical industry, government, insurance companies, and pharmacy benefit managers to adopt practices to ensure that antidotes are available to our patients and price are based on value and cost.
November 28, 2017: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29074147/cost-savings-impact-of-a-pharmacist-initiated-teleservice-program-for-medicare-part-d-reviews
#5
Colleen Massey, Timothy Dy Aungst, Paula Evans, Donna Bartlett, Matthew A Silva
OBJECTIVES: To (a) determine potential cost savings of a pharmacy outreach teleservice program conducting Medicare Part D plan reviews for a large population of beneficiaries allowing for comparison of multiple preferences; and (b) explore client demographic comparisons, plan features, and stratification by cost and number of medications. METHODS: Retrospective cohort evaluation of a Medicare D review service during open enrollment period (October 15 to December 7, 2012)...
October 23, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29050762/whole-genome-sequencing-for-the-management-of-drug-resistant-tb-in-low-income-high-tb-burden-settings-challenges-and-implications
#6
REVIEW
Sharana Mahomed, Kogieleum Naidoo, Navisha Dookie, Nesri Padayatchi
Drug-resistant tuberculosis is emerging as a major global health challenge, fuelled by a limited formulary and reduced ability to timeously diagnose resistance. Furthermore, poorly managed drug-resistant tuberculosis is complicated by poor treatment outcomes and high rates of morbidity and mortality. A rapid diagnosis together with individualized management are essential in order to limit disease and curtail transmission. Recently, the feasibility of Whole Genome Sequencing (WGS) technology for the routine diagnosis and drug susceptibility testing of Mycobacterium Tuberculosis in a high income, low tuberculosis burden setting, was demonstrated...
December 2017: Tuberculosis
https://www.readbyqxmd.com/read/29049325/effect-of-therapeutic-interchange-on-medication-reconciliation-during-hospitalization-and-upon-discharge-in-a-geriatric-population
#7
Jessica S Wang, Robert L Fogerty, Leora I Horwitz
BACKGROUND: Therapeutic interchange of a same class medication for an outpatient medication is a widespread practice during hospitalization in response to limited hospital formularies. However, therapeutic interchange may increase risk of medication errors. The objective was to characterize the prevalence and safety of therapeutic interchange. METHODS AND FINDINGS: Secondary analysis of a transitions of care study. We included patients over age 64 admitted to a tertiary care hospital between 2009-2010 with heart failure, pneumonia, or acute coronary syndrome who were taking a medication in any of six commonly-interchanged classes on admission: proton pump inhibitors (PPIs), histamine H2-receptor antagonists (H2 blockers), hydroxymethylglutaryl CoA reductase inhibitors (statins), angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and inhaled corticosteroids (ICS)...
2017: PloS One
https://www.readbyqxmd.com/read/29018301/a-p-t-committee-s-transition-to-a-complete-electronic-meeting-system-a-multisite-institution-experience
#8
Ahmed H Al-Jedai, Roaa A Algain, Said A Alghamidi, Abdulrazaq S Al-Jazairi, Rashid Amin, Ibrahim Z Bin Hussain
PURPOSE: In the last few decades, changes to formulary management processes have taken place in institutions with closed formulary systems. However, many P&T committees continued to operate using traditional paper-based systems. Paper-based systems have many limitations, including confidentiality, efficiency, open voting, and paper wastage. This becomes more challenging when dealing with a multisite P&T committee that handles formulary matters across the whole health care system. In this paper, we discuss the implementation of the first paperless, completely electronic, Web-based formulary management system across a large health care system in the Middle East...
October 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28986140/barriers-to-and-facilitators-of-independent-non-medical-prescribing-in-clinical-practice-a-mixed-methods-systematic-review
#9
Timothy Noblet, John Marriott, Emma Graham-Clarke, Alison Rushton
QUESTION: What are the factors that affect the implementation or utilisation of independent non-medical prescribing (iNMP)? DESIGN: Mixed-methods systematic review. Two reviewers independently completed searches, eligibility and quality assessments. DATA SOURCES: Pre-defined search terms were utilised to search electronic databases. Reference lists, key journals and grey literature were searched alongside consultation with authors/experts...
October 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28980145/a-systematic-approach-for-the-prevention-and-reduction-of-hypoglycemia-in-hospitalized-patients
#10
REVIEW
Paulina Cruz, Mary Clare Blackburn, Garry S Tobin
PURPOSE OF REVIEW: Hypoglycemia and severe hypoglycemia (SH) in the inpatient setting are associated with poor outcomes. This review is designed to highlight approaches to predict and prevent inpatient hypoglycemia that has been successfully implemented focusing on developing overlapping policies and procedures that allow safe glycemic management to occur at all levels of the institution. RECENT FINDINGS: Standardizing point-of-care (POC) testing, nursing protocols, meal delivery, and formulary restriction are useful tools to prevent hypoglycemia...
October 5, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28978207/chemotherapy-induced-nausea-and-vomiting-roles-of-pharmacists-and-formulary-decision-makers
#11
Stacey W McCullough
Despite guidelines and medications available for the management of chemotherapy-induced nausea and vomiting (CINV), many patients with cancer are persistently affected by this dreadful adverse effect. It is not only physically and mentally draining, but financially strenuous as well. Along with these concerns, health-related consequences as dehydration, epigastric pain, and anorexia can arise. Therefore, compliance becomes a big issue in this patient population. It is important for healthcare professionals to educate patients and incorporate strategies by not only addressing but also individualizing treatment regimens and determining risk factors for potential CINV...
September 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28963995/development-of-one-paediatric-and-one-neonatal-formulary-list-in-hospital-settings
#12
S S Haslund-Krog, H Rolighed Christensen, M Bjerager, H Holst
AIM: To describe the stepwise process towards creating two formulary lists - one for paediatric and one for neonatal patients covering common diseases in hospital settings. METHODS: This study presents the concept for developing a formulary list. How to: 1) organize the editorial board, 2) procure drug consumption data and database management, including information on labelling status, dosing options, excipients and problematic adverse events, current guidelines, evidence and price, 3) develop the first edition for the formulary list and formulary manual, 4) to establish a paediatric sub-committee within the Regional Drug and Therapeutic Committee to maintain and continually develop the two formularies...
September 30, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28944733/performance-based-risk-sharing-arrangements-for-pharmaceutical-products-in-the-united-states-a-systematic-review
#13
Justin S Yu, Lauren Chin, Jennifer Oh, Jorge Farias
BACKGROUND: Value for money is a growing necessity in today's U.S. health care system in which drug spending is expected to increase by an average rate of 6.7% yearly through 2025. In response to uncertainty about real-world clinical and economic outcomes for many drugs, health insurers and pharmacy benefit managers (PBMs) have implemented various contracts and arrangements with drug manufacturers that can collectively be described as performance-based risk-sharing arrangements (PBRSAs)...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28885970/essential-medications-for-patients-with-suspected-or-confirmed-ebola-virus-disease-in-resource-limited-environments
#14
William F Pierce, Selena D Ready, John Tyson Chapman, Corrinne Kulick, Anastasia Shields, Jialynn Wang, Kimberly Andrews, Richard W Childs, Carlos Bell, Alexandr Kosyak, Jade Pham
BACKGROUND: In 2014, the U.S. Public Health Service (USPHS) Commissioned Corps deployed to Monrovia, Liberia, to operate a 25-bed Ebola treatment unit (ETU) constructed by the U.S. Military. The ETU was named the Monrovia Medical Unit (MMU) and was constructed from an U.S. Air Force Expeditionary Medical Support (EMEDS) unit with modifications on the basis of consultation from Médecins Sans Frontières, the World Health Organization, and expert panels from the U.S. Department of Defense and Department of Health and Human Services...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28880046/clinical-decisions-support-malfunctions-in-a-commercial-electronic-health-record
#15
Steven Z Kassakian, Thomas R Yackel, Paul N Gorman, David A Dorr
OBJECTIVES: Determine if clinical decision support (CDS) malfunctions occur in a commercial electronic health record (EHR) system, characterize their pathways and describe methods of detection. METHODS: We retrospectively examined the firing rate for 226 alert type CDS rules for detection of anomalies using both expert visualization and statistical process control (SPC) methods over a five year period. Candidate anomalies were investigated and validated. RESULTS: Twenty-one candidate CDS anomalies were identified from 8,300 alert-months...
September 6, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28854079/identification-of-patients-with-statin-intolerance-in-a-managed-care-plan-a-comparison-of-2-claims-based-algorithms
#16
Brandon K Bellows, Amy M Sainski-Nguyen, Cody J Olsen, Susan H Boklage, Scott Charland, Matthew P Mitchell, Diana I Brixner
BACKGROUND: While statins are safe and efficacious, some patients may experience statin intolerance or treatment-limiting adverse events. Identifying patients with statin intolerance may allow optimal management of cardiovascular event risk through other strategies. Recently, an administrative claims data (ACD) algorithm was developed to identify patients with statin intolerance and validated against electronic medical records. However, how this algorithm compared with perceptions of statin intolerance by integrated delivery networks remains largely unknown...
September 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28836947/country-and-regional-variations-in-purchase-prices-for-essential-cancer-medications
#17
Raphael E Cuomo, Robert L Seidman, Tim K Mackey
BACKGROUND: Accessibility to essential cancer medications in low- and middle-income countries is threatened by insufficient availability and affordability. The objective of this study is to characterize variation in transactional prices for essential cancer medications across geographies, medication type, and time. METHODS: Drug purchase prices for 19 national and international buyers (representing 29 total countries) between 2010 and 2014 were obtained from Management Sciences for Health...
August 24, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28820648/natural-bioactive-food-components-for-improving-enteral-tube-feeding-tolerance-in-adult-patient-populations
#18
Adam J Kuchnia, Beth Conlon, Norman Greenberg
Tube feeding (TF) is the most common form of nutrition support. In recent years, TF administration has increased among patient populations within and outside hospital settings, in part due to greater insurance coverage, reduced use of parenteral nutrition, and improved formularies suitable for sole source nutrition. With increasing life expectancy and improved access to TFs, the number of adults dependent on enteral nutrition is expected to grow. However, enteral TF intolerance (ETFI) is the most common complication of TFs, typically presenting with at least 1 adverse gastrointestinal event, including nausea, diarrhea, and constipation...
August 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28814375/influencers-of-generic-drug-utilization-a-systematic-review
#19
REVIEW
Jennifer N Howard, Ilene Harris, Gavriella Frank, Zippora Kiptanui, Jingjing Qian, Richard Hansen
INTRODUCTION: With an increase in prescription drug spending and rising drug costs there is a need to encourage the use of generic prescription drugs. However, maximizing generic drug use is not possible without the public's positive perception and meeting their informational needs about generic drugs. Thus, improving the public's confidence in, and knowledge of generic drugs on the market is critical. The objective of this systematic review is to examine and evaluate the studies focusing on the nature and extent of key factors influencing generic drug use in the United States in order to help guide policy, education and practice interventions...
August 4, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28810127/medicaid-prior-authorization-and-opioid-medication-abuse-and-overdose
#20
Gerald Cochran, Adam J Gordon, Walid F Gellad, Chung-Chou H Chang, Wei-Hsuan Lo-Ciganic, Carroline Lobo, Evan Cole, Winfred Frazier, Ping Zheng, David Kelley, Julie M Donohue
OBJECTIVES: The US opioid medication epidemic has resulted in serious health consequences for patients. Formulary management tools adopted by payers, specifically prior authorization (PA) policies, may lower the rates of opioid medication abuse and overdose. We compared rates of opioid abuse and overdose among enrollees in plans that varied in their use of PA from "High PA" (ie, required PA for 17 to 74 opioids), with "Low PA" (ie, required PA for 1 opioid), and "No PA" policies for opioid medications...
May 1, 2017: American Journal of Managed Care
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