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https://www.readbyqxmd.com/read/28748733/sensory-symptoms-in-low-back-pain-how-do-they-matter
#1
Janne Gierthmühlen, Jessica Greinacher, Johanna Höper, Violetta Oberlojer, Michael Lankes, Frieder Traulsen, Philipp Hüllemann, Christoph Borzikowsky, Maren Reimer, Ralf Baron
OBJECTIVE: Successful treatment of chronic low back pain (LBP) is difficult in clinical practice and hard to measure in trials. One reason might be the use of insufficient outcome parameters. The aim was to investigate the importance of typical clinical characteristics of chronic LBP on QoL and functionality. METHODS: A total of 51 patients with chronic LBP (19 with, 32 without radiculopathy) were investigated with different questionnaires. RESULTS: Burdening symptoms differed in frequency, intensity and impairment of QoL and functionality between patients with and without radiculopathy and between the area of pain within the same patient, i...
July 27, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28746413/insomnia-with-objective-short-sleep-duration-is-associated-with-longer-duration-of-insomnia-in-the-freiburg-insomnia-cohort-compared-to-insomnia-with-normal-sleep-duration-but-not-with-hypertension
#2
Anna F Johann, Elisabeth Hertenstein, Simon D Kyle, Chiara Baglioni, Bernd Feige, Christoph Nissen, Alastair J McGinness, Dieter Riemann, Kai Spiegelhalder
STUDY OBJECTIVES: To replicate the association between insomnia with objective short sleep duration and hypertension, type 2 diabetes and duration of insomnia. DESIGN: Retrospective case-control study. SETTING: Department of Psychiatry and Psychotherapy, Medical Center-University of Freiburg. PARTICIPANTS: 328 patients with primary insomnia classified according to DSM-IV criteria (125 males, 203 females, 44.3 ± 12.2 years)...
2017: PloS One
https://www.readbyqxmd.com/read/28744094/patient-considerations-in-ocular-hypertension-role-of-bimatoprost-ophthalmic-solution
#3
REVIEW
Daniel Lee, Anand V Mantravadi, Jonathan S Myers
Glaucoma is a leading cause of irreversible blindness worldwide. The reduction of intraocular pressure has been well established as an effective treatment to prevent both the development and the progression of all forms of glaucoma. Bimatoprost 0.03% ophthalmic solution, introduced in 2001, is a synthetic prostamide with the unique mechanism of improving both uveoscleral and trabecular outflow. Comparative studies with other pharmacotherapies have shown favorable results for bimatoprost as a potent ocular hypotensive agent that is generally well tolerated...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28744054/the-effects-of-progressive-neuromuscular-training-on-postural-balance-and-functionality-in-elderly-patients-with-knee-osteoarthritis-a-pilot-study
#4
Sergio Sazo-Rodríguez, Guillermo Méndez-Rebolledo, Eduardo Guzmán-Muñoz, Paulo Rubio-Palma
[Purpose] To determine the effects of progressive neuromuscular training on postural balance and functionality in elderly patients with knee osteoarthritis (OA). [Subjects and Methods] Eleven participants between 60 and 75 years of age performed the progressive neuromuscular training for 8 weeks and 4 weeks of follow-up. The area and velocity of the center of pressure were measured on a force platform, and the functionality was measured with a Western Ontario and McMaster Universities Osteoarthritis Index...
July 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28743756/on-the-question-of-fractal-packing-structure-in-metallic-glasses
#5
Jun Ding, Mark Asta, Robert O Ritchie
This work addresses the long-standing debate over fractal models of packing structure in metallic glasses (MGs). Through detailed fractal and percolation analyses of MG structures, derived from simulations spanning a range of compositions and quenching rates, we conclude that there is no fractal atomic-level structure associated with the packing of all atoms or solute-centered clusters. The results are in contradiction with conclusions derived from previous studies based on analyses of shifts in radial distribution function and structure factor peaks associated with volume changes induced by pressure and compositional variations...
July 25, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28743580/comparison-of-balance-strategies-in-mountain-climbers-during-real-altitude-exposure-between-1-500m-and-3-200m-effects-of-age-and-expertise
#6
Anne-Violette Bruyneel, Arnaud Humbert, Marc Bertrand Ing
PURPOSE: The aim of this study was to estimate the effect of altitude (1500m vs. 3200m) on balance strategies, and to determine the influence of age (> or <40 years) and expertise (> or <20days of mountain climbing/year) on postural stability at altitude. METHOD: Eighty-nine volunteer mountaineers were tested at 1500m, 3200m immediately after exiting the cable car and at 3200m following the climb and return. Double-leg stance with eyes closed and single-leg stance with eyes open were tested...
July 22, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28743527/effectiveness-and-complications-of-augmentation-cystoplasty-with-or-without-non-refluxing-ureteral-reimplantation-in-adult-patients-with-long-standing-bladder-dysfunction-a-single-center-11-year-experience-in-173-cases
#7
Zhaoxia Wang, Limin Liao
PURPOSE: To review our experience for effectiveness and complications of augmentation cystoplasty (AC) with or without non-refluxing ureteral reimplantation in adult patients with long-standing bladder dysfunction MATERIAL AND METHODS: We retrospectively reviewed 173 patients who underwent AC with or without ureteral re-implantation (UR) at our center from July 2005 to July 2016. Clinical data, magnetic resonance urography (MRU), and video-urodynamics (VUD) parameters were collected. The upper urinary tract dilation (UUTD) and vesicoureteral reflux (VUR) grading systems were used to evaluate upper urinary tract function...
July 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28742700/comparison-of-postoperative-outcomes-between-donation-after-circulatory-death-and-donation-after-brain-death-liver-transplantation-using-the-comprehensive-complication-index
#8
Marit Kalisvaart, Jubi E de Haan, Wojciech G Polak, Herold J Metselaar, Bas P L Wijnhoven, Jan N M IJzermans, Jeroen de Jonge
OBJECTIVE: To test the total burden of complications in the early postoperative period after liver transplantation (LT) between donation after circulatory death (DCD) and donation after brain death (DBD) grafts with the novel Comprehensive Complication Index (CCI). BACKGROUND: LT is complex surgery and the increasing use of high-risk grafts is pressuring current postoperative outcomes. DCD grafts in particular are associated with ischemic-type biliary lesions (ITBL) with subsequent impaired graft survival rates...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742632/the-middle-ear-cleft-status-in-a-natural-cohort-with-eustachian-tube-dysfunction
#9
Udi Cinamon, Dov Albukrek, Yahav Oron, Sharon Ovnat Tamir, Abraham Goldfarb, David Dvir, Tal Marom
BACKGROUND: The Eustachian tube (ET) has a major role in the middle ear (ME) pressure homeostasis. ET dysfunction is the accepted paradigm for pressure-related ME disorders. We studied the ME status in patients with severely diminished ET opening abilities, and anticipated to find ME disorders in most of them. PATIENTS AND METHODS: ME status was evaluated in unconscious adults, who were hospitalized in a rehabilitation center with severe brain damage, requiring tracheotomy and gastrostomy...
July 24, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28742605/predictors-of-the-biomechanical-effects-of-customized-foot-orthoses-in-adults-with-flat-arched-feet
#10
John B Arnold, Thomas May, Christopher Bishop
OBJECTIVE: To determine the potential presence and characteristics of biomechanical responders to customized foot orthoses during walking in adults with flat-arched feet. DESIGN: Experimental, repeated-measures. SETTING: University clinic and laboratory. PARTICIPANTS: Eighteen symptom-free adults with flat-arched feet. INTERVENTIONS: Customized foot orthoses. MAIN OUTCOME MEASURES: In-shoe foot biomechanics were measured during walking with and without customized foot orthoses using 3D analysis...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28741360/influence-of-chemical-mechanical-and-transport-processes-on-wellbore-leakage-from-geologic-co2-storage-reservoirs
#11
Susan A Carroll, Jaisree Iyer, Stuart D C Walsh
Wells are considered to be high-risk pathways for fluid leakage from geologic CO2 storage reservoirs, because breaches in this engineered system have the potential to connect the reservoir to groundwater resources and the atmosphere. Given these concerns, a few studies have assessed leakage risk by evaluating regulatory records, often self-reported, documenting leakage in gas fields. Leakage is thought to be governed largely by initial well-construction quality and the method of well abandonment. The geologic carbon storage community has raised further concerns because acidic fluids in the CO2 storage reservoir, alkaline cement meant to isolate the reservoir fluids from the overlying strata, and steel casings in wells are inherently reactive systems...
July 25, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28741142/proteomic-expression-changes-in-large-cerebral-arteries-after-experimental-subarachnoid-hemorrhage-in-rat-are-regulated-by-the-mek-erk1-2-pathway
#12
Anne H Müller, Alistair V G Edwards, Martin R Larsen, Janne Nielsen, Karin Warfvinge, Gro K Povlsen, Lars Edvinsson
Subarachnoid hemorrhage (SAH) is a serious clinical condition where leakage of blood into the subarachnoid space causes an acute rise in intracranial pressure and reduces cerebral blood flow, which may lead to delayed cerebral ischemia and poor outcome. In experimental SAH, we have previously shown that the outcome can be significantly improved by early inhibition of the MAPK/ERK kinase/extracellular signal-regulated kinase (MEK/ERK1/2) pathway. The aim of this study was to apply mass spectrometry to investigate the overall late effects of experimental SAH on cerebrovascular protein expression...
July 24, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28740217/emergent-electronic-structure-of-cafe2as2
#13
Khadiza Ali, Kalobaran Maiti
CaFe2As2 exhibits collapsed tetragonal (cT) structure and varied exotic behaviour under pressure at low temperatures that led to debate on linking the structural changes to its exceptional electronic properties like superconductivity, magnetism, etc. Here, we investigate the electronic structure of CaFe2As2 forming in different structures employing density functional theory. The results indicate that the stability of the cT phase under pressure arises from the enhancement in hybridization induced effects and shift of the energy bands towards lower energies...
July 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28739273/analysis-of-packing-microstructure-and-wall-effects-in-a-narrow-bore-ultrahigh-pressure-liquid-chromatography-column-using-focused-ion-beam-scanning-electron-microscopy
#14
Arved E Reising, Sabine Schlabach, Vasili Baranau, Daniela Stoeckel, Ulrich Tallarek
Column wall effects are well recognized as major limiting factor in achieving high separation efficiency in HPLC. This is especially important for modern analytical columns packed with small particles, where wall effects dominate the band broadening. Detailed knowledge about the packing microstructure of packed analytical columns has so far not been acquired. Here, we present the first three-dimensional reconstruction protocol for these columns utilizing focused ion-beam scanning electron microscopy (FIB-SEM) on a commercial 2...
July 14, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28738862/impact-of-ischemic-preconditioning-on-surgical-treatment-of-brain-tumors-a-single-center-randomized-double-blind-controlled-trial
#15
Arthur H A Sales, Melanie Barz, Stefanie Bette, Benedikt Wiestler, Yu-Mi Ryang, Bernhard Meyer, Martin Bretschneider, Florian Ringel, Jens Gempt
BACKGROUND: Postoperative ischemia is a frequent phenomenon in patients with brain tumors and is associated with postoperative neurological deficits and impaired overall survival. Particularly in the field of cardiac and vascular surgery, the application of a brief ischemic stimulus not only in the target organ but also in remote tissues can prevent subsequent ischemic damage. We hypothesized that remote ischemic preconditioning (rIPC) in patients with brain tumors undergoing elective surgical resection reduces the incidence of postoperative ischemic tissue damage and its consequences...
July 25, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28738750/pregnancy-outcome-in-patients-with-takayasu-s-arteritis-cohort-study-and-review-of-the-literature
#16
Michal Kirshenbaum, Michal J Simchen, Ramat Gan
OBJECTIVE: To investigate the clinical features of pregnancy in women with Takayasu's arteritis managed in a tertiary medical center and review the literature in order to establish the course and recommended follow up and treatment for these pregnancies. MATERIALS AND METHODS: Retrospective analysis of 20 pregnancies in 6 women with Takayasu's arteritis. Patients were recruited from the high risk pregnancy clinics at Sheba Medical Center, where follow up included strict control of blood pressure and treatment of obstetric and disease related complications...
July 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28738490/-the-efficacy-and-safety-of-ultrafiltration-for-patients-with-heart-failure-results-from-a-single-center-randomized-controlled-study
#17
X L Shen, L B Y Zu, L Li, J Ma, B J Zhang, S B Jiang
Objective: To evaluate the efficacy and safety of ultrafiltration in patients with heart failure. Methods: One hundred and thirty four cases of patients with heart failure, who hospitalized in our hospital from June 2010 to June 2016 were enrolled in this study. Random serial number was generated using SPSS 22.0 software, patients were then randomly divided into control group and ultrafiltration group with the proportion of 1∶1 (67 cases in each group). Patients in the control group received standard therapy...
July 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28738403/developing-consensus-based-priority-outcome-domains-for-trials-in-kidney-transplantation-a-multinational-delphi-survey-with-patients-caregivers-and-health-professionals
#18
Bénédicte Sautenet, Allison Tong, Karine E Manera, Jeremy R Chapman, Anthony N Warrens, David Rosenbloom, Germaine Wong, John Gill, Klemens Budde, Lionel Rostaing, Lorna Marson, Michelle A Josephson, Peter P Reese, Timothy L Pruett, Camilla S Hanson, Donal O'Donoghue, Helen Tam-Tham, Jean-Michel Halimi, Jenny I Shen, John Kanellis, John D Scandling, Kirsten Howard, Martin Howell, Nick Cross, Nicole Evangelidis, Philip Masson, Rainer Oberbauer, Samuel Fung, Shilpa Jesudason, Simon Knight, Sreedhar Mandayam, Stephen P McDonald, Steve Chadban, Tasleem Rajan, Jonathan C Craig
BACKGROUND: Inconsistencies in outcome reporting and frequent omission of patient-centered outcomes can diminish the value of trials in treatment decision making. We identified critically important outcome domains in kidney transplantation based on the shared priorities of patients/caregivers and health professionals. METHODS: In a 3-round Delphi survey, patients/caregivers and health professionals rated the importance of outcome domains for trials in kidney transplantation on a 9-point Likert scale and provided comments...
August 2017: Transplantation
https://www.readbyqxmd.com/read/28737600/an-interprofessional-quality-improvement-initiative-to-standardize-pediatric-extubation-readiness-assessment
#19
Samer Abu-Sultaneh, Acrista J Hole, Alvaro J Tori, Brain D Benneyworth, Riad Lutfi, Christopher W Mastropietro
OBJECTIVES: Establishing protocols to wean mechanical ventilation and assess readiness for extubation, with the goal of minimizing morbidity associated with extubation failure and prolonged mechanical ventilation, have become increasingly important in contemporary PICUs. The aim of this quality improvement initiative is to establish a respiratory therapist-led daily spontaneous breathing trial protocol to standardize extubation readiness assessment and documentation in our PICU. DESIGN: A quality improvement project...
July 21, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28737378/quantitative-mid-infrared-cavity-ringdown-detection-of-methyl-iodide-for-monitoring-applications
#20
Ibrahim Sadiek, Qiang Shi, Douglas Wallace, Gernot Friedrichs
Methyl iodide is a toxic halocarbon with diverse industrial and agricultural applications and is an important ocean-derived trace gas that contributes to the iodine burden of the atmosphere. Quantitative analysis of CH3I is mostly based on gas chromatography coupled with mass spectrometry or electron capture detection (GC-MS/ECD) as yet, which often limits the ability to conduct in situ high-frequency monitoring studies. This work presents an alternative detection scheme based on mid-infrared continuous wave cavity ringdown spectroscopy (mid-IR cw-CRDS)...
July 24, 2017: Analytical Chemistry
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