Donatella Coradduzza, Antonella Congiargiu, Emanuela Azara, Ismaeil Mohammed Abulkahar Mammani, Maria Rosaria De Miglio, Angelo Zinellu, Ciriaco Carru, Serenella Medici
The majority of the so-called heavy metals are suspected to be involved in a number of pathologies and play a role in human carcinogenesis. Some of them (i.e. arsenic (As), cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg) and nickel (Ni)) have been defined as carcinogens, increasing the susceptibility of tumor development and progression in humans. Moreover, Ni, Cr, Cd, Hg, and Pb together with zinc (Zn) and iron (Fe), may be capable of stimulating the progression of breast cancer and reducing a patient's sensitivity to treatment through alterations to DNA methylation...
February 12, 2024: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine