Mingming Yang, Toru Kondo, Carly Adamson, Jawad H Butt, William T Abraham, Akshay S Desai, Karola S Jering, Lars Køber, Mikhail N Kosiborod, Milton Packer, Jean L Rouleau, Scott D Solomon, Muthiah Vaduganathan, Michael R Zile, Pardeep S Jhund, John J V McMurray
BACKGROUND: Patients with heart failure (HF) often suffer from a range of comorbidities, which may affect their health status. OBJECTIVES: To assess the impact of different comorbidities on health status in patients with HF and reduced and preserved ejection fraction (HFrEF and HFpEF). METHODS: Using individual patient data from HFrEF (ATMOSPHERE, PARADIGM-HF, DAPA-HF) and HFpEF (TOPCAT, PARAGON-HF) trials, we examined the Kansas City Cardiomyopathy Questionnaire (KCCQ) domain scores and Overall Summary Score (KCCQ-OSS) across a range of cardio-respiratory (angina, AF, stroke, COPD) and other comorbidities (obesity, DM, CKD, anaemia)...
July 4, 2023: European Journal of Heart Failure