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Brain abscess in childhood

Norma de Oliveira Penido, Sujana Sreedevi Chandrasekhar, Andrei Borin, André Souza de Albuquerque Maranhão, José Ricardo Gurgel Testa
INTRODUCTION: It is an erroneous but commonly held belief that intracranial complications (ICCs) of chronic and acute otitis media (COM and AOM) are past diseases or from developing countries. These problems remain, despite improvements in antibiotic care. OBJECTIVE: This paper analyzes the occurrence and clinical characteristics and course of the main ICCs of otitis media (OM). METHODS: Retrospective cohort study of 51 patients with ICCs from OM, drawn from all patients presenting with OM to the emergency room of a large inner-city tertiary care hospital over a 22-year period...
May 2016: Brazilian Journal of Otorhinolaryngology
Gabriel Dabscheck, Lewis Silverman, Nicole J Ullrich
A 5-year-old boy with standard-risk B-cell acute lymphoblastic anemia developed fever during induction chemotherapy. The patient had no neurological symptoms. Blood cultures grew Bacillus cereus and neuroimaging studies demonstrated a cerebral abscess. Imaging changes resolved after completion of antibiotics. Bacillus cereus bacteremia is increasingly implicated as the cause of life-threatening infections, including cerebral abscesses, in compromised patients. Positive blood cultures for this organism should prompt neuroimaging and consideration of cerebrospinal fluid sampling, as well as catheter removal...
October 2015: Journal of Pediatric Hematology/oncology
Wilbroad Mutale, Keya M Sahay, John Hartley, Dominic Thompson, Didi Ratnasinghe, Lee Hudson, Eleanor Hulse, Greg Fellows
BACKGROUND: Brain abscess are uncommon childhood infection. Brain abscess caused by Panton-Valentine Leukocidin positive Community acquired Methicillin Resistant Staphylococcal aureus have never been reported in the United Kingdom. CASE PRESENTATION: We report a case of a previously well 11-month old boy of Indian origin who developed a parietal lobe abscess from PVL positive CA-MRSA. CONCLUSION: This case is one of the few described cases of brain abscess caused by PVL CA-MRSA in children...
2014: BMC Research Notes
Mehmet Canpolat, Ozgur Ceylan, Huseyin Per, Gonca Koc, Abdulfettah Tumturk, Sefer Kumandas, Turkan Patiroglu, Selim Doganay, Hakan Gumus, Ekrem Unal, Mehmet Kose, Sureyya Burcu Gorkem, Ali Kurtsoy, Mustafa Kursat Ozturk
Childhood brain abscesses are a rare and potentially life-threatening condition requiring urgent diagnosis and treatment. This retrospective study analyzed the clinical and radiologic findings of 24 (7 girl, 17 boys) cases with brain abscess. Mean age was 92.98 ± 68.04 months. The most common presenting symptoms were nausea-vomiting (45.8%) and headache (41.7%). Brain abscess was most commonly located in the frontal region. Diffusion restriction was determined in 78.4% of lesions. The mean apparent diffusion coefficient value in these lesions was 0...
March 2015: Journal of Child Neurology
Alessia Claps, Martina Della Corte, Simona Gerocarni Nappo, Paola Francalanci, Paolo Palma, Andrea Finocchi
BACKGROUND: Chronic granulomatous disease (CGD) is a primary immunodeficiency resulting from the absence or malfunction of oxidative mechanism in phagocytic cells. The disease is due to a mutation in one of four genes that encode subunits of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. Affected patients experience severe infections and granuloma formation due to exuberant inflammatory responses. Some evidence suggests that eosinophilic cystitis (EC) is included in the spectrum of inflammatory manifestations...
November 2014: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Jorge Humberto Davila Acosta, Claudia Isabel Lazarte Rantes, Andres Arbelaez, Feliza Restrepo, Mauricio Castillo
Infections of the central nervous system (CNS) are a very common worldwide health problem in childhood with significant morbidity and mortality. In children, viruses are the most common cause of CNS infections, followed by bacterial etiology, and less frequent due to mycosis and other causes. Noncomplicated meningitis is easier to recognize clinically; however, complications of meningitis such as abscesses, infarcts, venous thrombosis, or extra-axial empyemas are difficult to recognize clinically, and imaging plays a very important role on this setting...
June 2014: Topics in Magnetic Resonance Imaging: TMRI
Joanna Załęska-Ponganis, Teresa Jackowska
Acute otitis media (AOM) is the most commonly diagnosed childhood disease, especially in infants and preschool children. Onset of AOM encourage frequent upper respiratory infections and debilitating conditions that cause nasal patency and trumpets auditory dysfunction. Complications of AOM currently are rare. We present a case of complications of acute otitis media in form of acute cerebral abscess in a 7-year-old previously healthy girl.
October 2013: Medycyna Wieku Rozwojowego
Ahmad R Sedaghat, Claus O Wilke, Michael J Cunningham, Stacey L Ishman
OBJECTIVES/HYPOTHESIS: To identify characteristics and disparities associated with presentation of pediatric acute bacterial sinusitis (ABS) complications. STUDY DESIGN: A cross-sectional study of the 2008 Nationwide Emergency Department Sample database. METHODS: A total of 101,660 children 18 years of age or younger diagnosed with ABS, 696 of whom had orbital or intracranial complications, were identified. Patient and hospital-specific characteristics were investigated for association with childhood ABS complications...
July 2014: Laryngoscope
Philippe Lepage, Bernard Dan
Bacterial meningitis (BM) remains a major global challenge. Globally, Hib, S. pneumoniae, and N. meningitidis cause about 90% of cases of BM beyond the neonatal period. After colonization of the upper respiratory tract by one of these pathogens, invasion occurs across the epithelium. Following entry into the bloodstream, bacteria survive through evasion of the complement system. Once into the CSF, bacteria multiply very actively. The clinical features of BM depend on the age of the patient, duration of illness, the pathogen involved, and host response to infection...
2013: Handbook of Clinical Neurology
V P Djientcheu, T F Mouafo, A Esiene, Y N Kamga, S Nguefack, F Bello, T Y Yamgoue, Z C Ongolo, E Mbonda
INTRODUCTION: Intracranial suppurations (ICS) are collections of pus of infectious origin in the skull. The authors present their experience. PATIENTS AND METHOD: All children operated for ICS at the Central Hospital of Yaoundé from January 2000 to December 2008 were retrospectively included. RESULTS: Thirty-five patients were recruited: 26 (74.29 %) males and 9 (25.71 %) females. These represent 82.9 % of all ICS operated in our institution...
January 2013: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Theresa S Cole, Marcia E Clark, Alistair J Jenkins, Julia E Clark
PURPOSE: Brain abscess (BA) and subdural empyema (SDE) are uncommon but clinically important conditions in childhood. Treatment involves surgery and prolonged courses of antibiotics. There is no consensus on the optimal approach. The objective was to review management and outcome of BA and SDE in a single UK center. METHODS: This retrospective case notes review of children with brain abscess or subdural empyema admitted to a tertiary pediatric infectious diseases and neurosurgical center from 2001 to 2009...
December 2012: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Siba Prosad Paul, Susie Jerwood
Group A streptococcus (GAS) is a global bacterial pathogen. It is a rare cause of central nervous system infections and accounts for about 1% of all childhood meningitis. Otitis media or sinusitis has been reported as a risk factor for brain abscess in invasive GAS diseases. We present the case of a previously healthy boy with GAS sepsis and meningitis. He subsequently developed a brain abscess and needed a prolonged course of intravenous antibiotics.
March 2012: Turkish Journal of Pediatrics
Yasemin Ozsürekci, Ateş Kara, Ali Bülent Cengiz, Melda Celik, Aslinur Ozkaya-Parlakay, Eda Karadağ-Oncel, Mehmet Ceyhan
Brain abscess is an uncommon intracranial suppurative infectious disease, especially in children. The clinical presentation, treatment and outcome of 75 children with brain abscesses admitted to the Department of Pediatric Infectious Diseases at Hacettepe University Faculty of Medicine were retrospectively analyzed. Seventy-five cases of brain abscess within a 28-year period were included in this study. Fever and headache were the most common presenting symptoms. Cyanotic congenital heart disease was the most common predisposing factor...
March 2012: Turkish Journal of Pediatrics
Bhavini S Acharya, Priyanshi Ritwik, Gisela M Velasquez, Sanford J Fenton
Infantile Refsum disease (IRD) is a peroxisome biogenesis disorder (PBD), and is part of a larger group of diseases called leukodystrophies, which are inherited conditions that damage the white matter of the brain and affect motor movements. Multiple signs and symptoms of IRD begin in infancy and progress through early childhood, including hearing and visual impairment, intellectual and growth impairment, seizures, liver involvement, and orofacial and dental abnormalities. This paper presents a case history of a 12-year-old female patient with IRD who underwent dental rehabilitation in the operating room under general anesthesia and includes a 2-year follow-up...
June 2012: Special Care in Dentistry
Shakeel A Chowdhry, Alan R Cohen
PURPOSE: Citrobacter koseri, a facultatively anaerobic, lactose-fermenting, gram-negative bacilli, has a strong propensity to form cerebral abscesses. C. koseri brain abscesses can be a devastating disease of infancy and childhood with more than 30% succumbing to the disease and more than 50% suffering severe neurological deficits. METHODS: This study represents a retrospective review of two cases of C. koseri brain abscesses along with a review of the literature regarding diagnosis and treatment...
October 2012: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Jing-Qi Zhu, Nan-Xin Hao, Wei-Qun Bao, Xiang-Ru Wu
BACKGROUND: Multiple calcified primary central nervous system lymphoma (PCNSL) is extremely rare in childhood. METHODS: We report a 4-year-old boy suffering from multiple calcified B-cell lymphoma in the brain with immunodeficiency. RESULTS: The boy had a history of walking weakness and seizure for 4 months. The serum levels of immunoglobulin G, A and M were decreased. Brain MRI showed multiple lesions which had ring enhancement. CT showed calcification in all of the lesions...
August 2011: World Journal of Pediatrics: WJP
Atsushi Yoshida, Kiki Maoate, Russell Blakelock, Stephen Robertson, Spencer Beasley
BACKGROUND: The aim of the study was to review the degree to which the long-term outcome and ongoing morbidity in Currarino syndrome (CS) has been established. METHODS: Analysis of previously published reports that have included long-term outcome data in CS and review of five additional patients with CS. RESULTS: Overall, long-term outcomes of children born with CS are not well described. Malignancy has been reported in six children of approximately 300 CS patients: four children with malignancy had a recurrence after primary excision...
July 2010: Pediatric Surgery International
Tamara Keith, Sonia Saxena, Joanna Murray, Mike Sharland
PURPOSE OF REVIEW: Most childhood respiratory infections including acute otitis media (AOM), sore throat, upper respiratory tract infections (URTIs) and sinusitis are self-limiting illnesses. Yet, despite extensive guidance discouraging routine use of antibiotics to limit side-effects and combat antimicrobial resistance, antibiotic prescribing for these conditions remains high in many developed countries, fuelled by the fear of rare but serious bacterial complications including mastoiditis, quinsy, pneumonia and brain abscess...
June 2010: Current Opinion in Infectious Diseases
Tony E O'Connor, Christopher F Perry, Francis J Lannigan
In Australia, three to five children die each year because of otitis media complications, and 15 children will suffer permanent hearing loss each year as a result of otitis media. Extracranial complications occur most commonly, and include mastoiditis, cholesteatoma and otitis media with perforation. Intracranial complications are less common, and include meningitis, brain abscess and lateral sinus thrombosis. In Australia, approximately 60% of extracranial and intracranial complications of otitis media occur in children...
November 2, 2009: Medical Journal of Australia
Natália Melo, Vicens Diaz-Brito, Clara Chamadoira, Isabel Gomes, Adelina Amorim
BACKGROUND: Brain abscess can arise as a complication of a variety of infections, trauma or surgery. Bacteria can invade the brain by direct spread or through haematogenous seeding. Brain abscesses are described as a rare complication of bronchiectasis. CASE DESCRIPTION: A 44 -year -old woman with pulmonary tuberculosis in childhood and with the diagnosis of bilateral extensive bronchiectasis who presented behaviour alterations and later, paresis of the sixth cranial nerve, was diagnosed multiple brain abscesses...
March 2009: Revista Portuguesa de Pneumologia
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