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https://www.readbyqxmd.com/read/27921018/comparison-of-the-protective-effects-of-erythropoietin-and-melatonin-on-renal-ischemia-reperfusion-injury
#1
Shokofeh Banaei, Nasser Ahmadiasl, Alireza Alihemmati
BACKGROUND: Renal ischemia-reperfusion (IR) contributes to the development of acute renal failure (ARF). Oxygen free radicals are considered to be the principal components involved in the pathophysiological tissue alterations observed during renal IR. OBJECTIVES: In this study, we compared the effects of melatonin (MEL) and erythropoietin (EPO), both known antioxidant and anti-inflammatory agents, on IR-induced renal injury in rats. MATERIALS AND METHODS: Wistar albino rats were unilaterally nephrectomized and then subjected to 45 minutes of renal pedicle occlusion followed by 24 hours of reperfusion...
July 2016: Trauma Monthly
https://www.readbyqxmd.com/read/27900487/lipoid-proteinosis-unveiled-by-oral-mucosal-lesions-a-comprehensive-analysis-of-137-cases
#2
Boaz Frenkel, Marilena Vered, Shlomo Taicher, Noam Yarom
OBJECTIVES: Lipoid proteinosis (LP) is a rare autosomal recessive disorder characterized by deposits of hyaline material within skin and mucous membranes of the upper aerodigestive tract, especially the vocal cords. We aimed to investigate possible associations between oral LP (oLP) manifestations and demographic data and extra-oral lesions. MATERIAL AND METHODS: Cases of oLP were collected following a systematic search of Medline's PubMed and Google Scholar (1948-2014)...
November 29, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27885296/outcome-of-twin-deliveries-at-a-tertiary-care-centre-of-eastern-nepal
#3
S Chaudhary, R R Singh, G S Shah, J Agrawal, S Kafle, L Shah
BACKGROUND: Twins, compared to singletons, have higher perinatal mortality and morbidity. The aim of this study was to describe the twinning rate, epidemiological variables and hospital outcome of twin deliveries and to find out ways of better management of twins in our part. METHODS: A retrospective evaluation of the outcome of 92 twin pregnancies during one year study period (1st January 2014 to 31st December 2014) was conducted at BPKIHS. Twins delivered within the institution were included but cases less than 28 weeks gestation were excluded...
May 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/27845943/broadening-the-anatomic-landscape-of-sclerosing-perineurioma-a-series-of-5-cases-in-nonacral-sites
#4
Emily M Erstine, Jennifer S Ko, Brian P Rubin, Jesse K McKenney, John R Goldblum, Steven D Billings
Sclerosing perineurioma is a rare perineurioma variant thought to occur almost exclusively in digits and palms, predominantly in young adult men. It clinically presents as a solitary slow-growing nodule, sometimes associated with prior trauma. Since 01/01/2000, our institution has received 5 cases in consultation of sclerosing perineurioma presenting in atypical locations. Four of 5 patients were women. The median age at presentation was 45 years (range, 31-62 years). Sites included dorsal tongue, anterior neck, mid upper back, forearm, and proximal anterior thigh...
November 11, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27824284/formation-of-hyaline-cartilage-tissue-by-passaged-human-osteoarthritic-chondrocytes
#5
Vanessa Juliana Bianchi, Joanna F Weber, Stephen D Waldman, David Backstein, Rita Kandel
Objective When serially passaged in standard monolayer culture to expand cell number, articular chondrocytes lose their phenotype. This results in the formation of fibrocartilage when they are used clinically, thus limiting their use for cartilage repair therapies. Identifying a way to redifferentiate these cells in vitro is critical if they are to be used successfully. Transforming growth factor beta (TGFβ) family members are known to be crucial for regulating differentiation of fetal limb mesenchymal cells and mesenchymal stromal cells to chondrocytes...
November 8, 2016: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27792064/seborrheic-keratosis-like-lesions-of-the-cervix-and-vagina-report-of-a-new-entity-possibly-related-to-low-risk-human-papillomavirus-infection
#6
Karen L Talia, W Glenn McCluggage
We report a series of 7 unusual and morphologically distinct cervical or upper vaginal lesions in women aged 41 to 70 years. The lesions involved the cervix in 3 cases, the upper vagina in 2, the cervix and vagina in 1, and in 1 case the site of origin could not be determined. The lesions had a consistent morphologic appearance with a surface "plaque-like" or "stuck-on" configuration apparent in those cases where surrounding normal tissues were present. Broad coalescing solid sheets and interconnecting trabeculae of cytologically bland cells with a rather "basaloid" appearance emanated from the surface and there were scattered squamous eddies...
October 27, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27789021/nasal-chondrocyte-based-engineered-autologous-cartilage-tissue-for-repair-of-articular-cartilage-defects-an-observational-first-in-human-trial
#7
Marcus Mumme, Andrea Barbero, Sylvie Miot, Anke Wixmerten, Sandra Feliciano, Francine Wolf, Adelaide M Asnaghi, Daniel Baumhoer, Oliver Bieri, Martin Kretzschmar, Geert Pagenstert, Martin Haug, Dirk J Schaefer, Ivan Martin, Marcel Jakob
BACKGROUND: Articular cartilage injuries have poor repair capacity, leading to progressive joint damage, and cannot be restored predictably by either conventional treatments or advanced therapies based on implantation of articular chondrocytes. Compared with articular chondrocytes, chondrocytes derived from the nasal septum have superior and more reproducible capacity to generate hyaline-like cartilage tissues, with the plasticity to adapt to a joint environment. We aimed to assess whether engineered autologous nasal chondrocyte-based cartilage grafts allow safe and functional restoration of knee cartilage defects...
October 22, 2016: Lancet
https://www.readbyqxmd.com/read/27788140/the-level-of-iga-antibodies-to-endothelial-cells-correlates-with-histological-evidence-of-disease-activity-in-patients-with-lupus-nephritis
#8
Ayako Kondo, Kazuo Takahashi, Tomohiro Mizuno, Akihiro Kato, Daisuke Hirano, Naoki Yamamoto, Hiroki Hayashi, Shigehisa Koide, Hiroshi Takahashi, Midori Hasegawa, Yoshiyuki Hiki, Shunji Yoshida, Keiji Miura, Yukio Yuzawa
Anti-endothelial cell antibodies (AECA) are frequently detected in patients with systemic lupus erythematosus (SLE), but their pathological role remains unclear. We recently developed a solubilized cell surface protein capture enzyme-linked immunosorbent assay (CSP-ELISA) to detect antibodies against membrane proteins involved in autoimmune reactions. In this study, sera from 51 patients with biopsy-proven lupus nephritis (LN), 25 with SLE without renal involvement (non-LN SLE), 42 disease control (DC) subjects, and 80 healthy control (HC) subjects were tested for IgG- and IgA-AECA for human umbilical vein endothelial cells (HUVEC) and human glomerular EC (HGEC) by using CSP-ELISA...
2016: PloS One
https://www.readbyqxmd.com/read/27718331/ovarian-clear-cell-carcinoma-with-plasma-cell-rich-inflammatory-stroma-cytological-findings-of-a-case
#9
Masayuki Shintaku, Makoto Dohi, Yoshihiro Yamamoto, Aya Nagai, Toshihiro Higuchi
We report a case of clear cell carcinoma (CCC) of the ovary with plasma cell-rich inflammatory stroma, a recently proposed subtype of CCC, and present the cytological findings. The patient was a 48-year-old woman, who was incidentally found to have a right ovarian tumor during the preoperative work-up for an early-stage adenocarcinoma of the uterine cervix. Cytological examination of an imprint smear of the ovarian tumor and peritoneal washing revealed solid cell clusters of irregular, often dendritic shapes, which were intermingled with many inflammatory cells...
October 8, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27671979/postoperative-complications-following-neonatal-and-infant-surgery-common-events-and-predictive-factors
#10
Daphné Michelet, Christopher Brasher, Houssam Ben Kaddour, Thierno Diallo, Rachida Abdat, Serge Malbezin, Arnaud Bonnard, Souhayl Dahmani
BACKGROUND: Data on major non-surgical postoperative complications following neonatal and infant surgery is lacking. The goal of the present study was to describe common major complications and their predictive factors. MATERIAL AND METHODS: The study consisted of a retrospective review of medical charts of patients less than 6months of age operated in our institution over one calendar year, excluding herniorraphy surgery. The data collected included demographics, preoperative ICU bed status, ASA status, a history of cardiac malformation, hyaline membrane disease (HMD) or necrotizing enterocolitis (NEC), preoperative haemoglobin, emergent surgery status, surgery type and duration, duration of anaesthesia and the need for intraoperative fluid boluses...
September 23, 2016: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/27642489/neonatal-respiratory-distress-in-a-reference-neonatal-unit-in-cameroon-an-analysis-of-prevalence-predictors-etiologies-and-outcomes
#11
Joel Noutakdie Tochie, Simeon-Pierre Choukem, Regina Ndasi Langmia, Esther Barla, Paul Koki-Ndombo
INTRODUCTION: Neonatal respiratory distress (NRD) is a main cause of neonatal morbidity and mortality in developing countries. Early detection of its risk factors and early treatment of its etiologies are major challenges. However, few studies in developing countries have provided data needed to tackle it. We aimed to determine the prevalence, predictors, etiologies and outcome of NRD in a tertiary health care centre of Cameroon. METHODS: We analyzed the hospital files of all newborns admitted to the Neonatal unit of Douala General Hospital from 1(st) January 2011 to 28(th) February 2013...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27618508/biokinetics-and-tissue-response-to-ultrananocrystalline-diamond-nanoparticles-employed-as-coating-for-biomedical-devices
#12
Deborah R Tasat, Marcos E Bruno, Mariela Domingo, Pablo Gurman, Orlando Auciello, María L Paparella, Pablo Evelson, María B Guglielmotti, Daniel G Olmedo
Although Ultrananocrystalline diamond (UNCD) has been proposed as a coating material for titanium biomedical implants, the biological effects and toxicity of UNCD particles that could eventually detach have not been studied to date. The biokinetics and biological effects of UNCD compared to titanium dioxide (TiO2 ) nanoparticles was evaluated in vivo using Wistar rats (n = 30) i.p. injected with TiO2 , UNCD or saline solution. After 6 months, blood, lung, liver, and kidney samples were histologically analyzed...
September 12, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27516042/clinical-and-histopathological-aspects-in-two-cases-of-ligneous-conjunctivitis
#13
Carmen LuminiŢa Mocanu, Maria Rodica Mănescu, Andreea Gabriela Deca, Ştefania CrăiŢoiu, Sanda Jurja
Ligneous conjunctivitis represents a very rare form of chronic membranous conjunctivitis, with unknown etiology; less than 200 cases have been reported in the literature, most of them in infants and children. After 40 years, this condition appears in exceptional circumstances. We present, in this study, two patients (of 55 and 64 years old) with very severe forms of ligneous conjunctivitis, certified by histopathological examination, one of them being previously diagnosed with Lyell's syndrome. The histological examination in ligneous conjunctivitis is important for diagnostic but also to elucidate the etiopathological context...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27456213/fine-needle-aspiration-cytology-of-cylindroma-of-scalp-a-case-report
#14
Subrata Pal, Kingshuk Bose, Mrinal Sikder, Manaj Chowdhury
Cylindromas are uncommon benign adnexal tumor. Multiple cylindromas are commonly genetically inherited and also known as "turban tumor." Cytology of dermal cylindroma is rarely discussed in previous literature. We have diagnosed a case of dermal cylindroma of scalp in an elderly female patient by fine needle aspiration cytology of the lesion and further confirmation was done by histopathology. Cytology consists of many clusters of small round to oval basaloid cells surrounded and attached with magenta coloured acellular hyaline material...
December 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27442626/primary-epithelioid-sarcoma-of-the-zygomatic-bone
#15
Henry Tran, Nick Shillingford, Stefanie Thomas, Jeffrey Hammoudeh, Shengmei Zhou
Primary epithelioid sarcoma of bone is extremely rare with only two reported cases in the English literature. A previously healthy 18-year-old male presented with a six-month history of right facial numbness and tingling and right eye diplopia. CT scan revealed an ill-defined mass with dense osseous matrix centered in the right zygomatic bone. An outside biopsy was read as osteosarcoma. The resection specimen revealed large epithelioid and spindle cells embedded in a prominent hyalinized matrix with focal metaplastic bone formation...
July 21, 2016: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/27407028/hyaline-globules-and-papillary-fragments-in-cytologic-smears-from-two-intra-abdominal-tumors-ovarian-and-hepatic-in-female-patients-a-diagnostic-pitfall-with-histologic-correlation
#16
Isidro Machado, María Victoria López-Soto, Albadio Samir Pérez-López, Carlos Domínguez-Álvarez, Antonio Llombart-Bosch
Hyaline globules and papillary fragments in cytologic samples from two intra-abdominal tumors in young females are presented including the cytological features and the correlation with the histopathologic and immunohistochemical findings. In the first case a cytologic study from an ovarian mass showed papillary structures and isolated tumor cells with epithelioid morphology, irregular reniform-like nuclear contour, pale or vacuolated cytoplasm, abundant hyaline globules and occasional glomeruloid structures resembling Schiller-Duval bodies...
July 13, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27406120/recurrent-corneal-melting-in-the-paraneoplastic-pemphigus-associated-with-castleman-s-disease
#17
Haijun Gong, Shiyou Zhou, Yuxin Hu, Yuqin Lan, Hong Zeng, Liangchun Wang, Qingyu Liu, Mei Wang
BACKGROUND: The ocular presentation of Castleman's disease (CD)-associated paraneoplastic pemphigus (PNP) has rarely been reported. In this report, we describe a young patient with CD-associated PNP who had recurrent corneal ulceration in addition to cicatrizing conjunctivitis. CASE PRESENTATION: We describe a case of 23-year-old male with mucocutaneous erosion and conjunctival injection and erosion who was found to have PNP. Pelvic hyaline-vascular CD was detected and completely excised...
2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27395539/two-new-species-of-parastenocarididae-copepoda-harpacticoida-from-india
#18
Yenumula Ranga Reddy, Venkateswara Rao Totakura, Shabuddin Shaik
To date, 20 species of Parastenocarididae are known from the Indian subcontinent. This paper gives the description of two more new species from the coastal deltaic belt of the Rivers Krishna and Godavari in the Andhra Pradesh state of the southeastern Indian peninsula. They are: Parastenocaris enckelli n. sp. from a hyporheic habitat, and Dussartstenocaris bisetosa n. sp. from a farm bore. Parastenocaris enckelli belongs to the brevipes-group of the genus Parastenocaris Kessler, 1913 sensu Lang 1948 and Reid 1995, and is characterized by the following features: the male leg 4 basal complex consists of a large chitinized plate, with two digitiform hyaline structures at its proximal outer corner of the anterior surface, and one smooth, moderately strong, claw-like spine at the inner distal corner of basis; the endopod of the same leg is membranous, with bulbous proximal part having a diagonal row of three spinules, and its distal part is drawn out into smooth pointed structure; and the male leg 3 ancestral proximal segment is subproximally dilated, elongate, with ladle-shaped apophysis, which is slightly longer than the spiniform thumb...
2016: Zootaxa
https://www.readbyqxmd.com/read/27272620/morphology-and-clinical-importance-of-epidural-membrane-and-periradicular-fibrous-tissue-in-lumbar-spinal-stenosis
#19
Akira Miyauchi, Tadayoshi Sumida, Mayumi Kaneko, Hideki Manabe, Nobuo Adachi
PURPOSE: Compared to the ligamentum flavum (LF), morphology of the epidural membrane (EM) and the periradicular fibrous tissue (PRFT) has been largely ignored in studies of lumbar spinal stenosis (LSS). The aim of this prospective study was to elucidate the morphologies and clinical importance of the EM and PRFT in LSS. METHODS: Before starting this study, neural compressive EM (c-EM) and PRFT (c-PRFT) were defined as follows based on our microsurgical experience and a literature review...
June 7, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27264610/equid-herpesvirus-type-1-and-rhodococcus-equi-coinfection-in-a-foal-with-bronchointerstitial-pneumonia
#20
Alejandro Perez-Ecija, Francisco Javier Mendoza, José Carlos Estepa, María José Bautista, José Pérez
A 2-month old foal with septic shock and severe respiratory distress was referred to the Veterinary Teaching Hospital. Due to poor prognosis, the foal was euthanized. Histopathology showed lesions suggestive of Rhodococcus equi infection associated with a diffuse interstitial infiltrate of foamy macrophages and syncytial cells presenting large acidophilic intranuclear inclusion bodies, fibrin exudates and hyaline membranes. Bacteriological examination from lung and respiratory exudates confirmed R. equi infection, whilst immunohistochemistry and PCR yielded a positive result for Equid herpesvirus type 1(EHV-1)...
June 3, 2016: Journal of Veterinary Medical Science
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