keyword
MENU ▼
Read by QxMD icon Read
search

Progesterone administration

keyword
https://www.readbyqxmd.com/read/28631553/administration-of-progesterone-throughout-pregnancy-increases-maternal-steroids-without-adverse-effect-on-mature-oligodendrocyte-immunostaining-in-the-guinea-pig
#1
Julia C Shaw, Hannah K Palliser, Kerrin Palazzi, Jonathan J Hirst
Progesterone is administered to pregnant women at risk of premature labor, despite systematic reviews showing conflicting outcomes regarding its use, highlighting doubt over the effectiveness of the therapy. Progesterone can be rapidly metabolized into a number of steroids, but to date, there has been a lack of investigation into the fetal steroid profiles following administration and whether this impacts fetal neurodevelopment. The objective of this study was to determine the effect of progesterone treatment on allopregnanolone and cortisol levels in the fetus and on a marker of myelination in the fetal brain...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28630099/kndy-neurone-activation-prior-to-the-lh-surge-of-the-ewe-is-disrupted-by-lps
#2
Chrysanthi Fergani, Jean Routly, David Jones, Lucy Pickavance, Robert Frank Smith, Hilary Dobson
In the ewe, steroid hormones act on the hypothalamic arcuate nucleus (ARC) to initiate the GnRH/LH surge. Within the ARC, steroid signal transduction may be mediated by dopamine, β-endorphin or neuropeptide Y (NPY) expressing cells, as well as those co-localising kisspeptin, neurokinin B (NKB), and dynorphin (termed KNDy). We investigated the time during the follicular phase when these cells become activated (i.e., co-localise c-Fos) relative to the timing of the LH surge onset and may, therefore, be involved in the surge generating mechanism...
June 19, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28628658/effects-of-obesogenic-diet-and-estradiol-on-dorsal-raphe-gene-expression-in-old-female-macaques
#3
Cynthia L Bethea, Kevin Mueller, Arubala P Reddy, Steven G Kohama, Henryk F Urbanski
The beneficial effects of bioidentical ovarian steroid hormone therapy (HT) during the perimenopause are gaining recognition. However, the positive effects of estrogen (E) plus or minus progesterone (P) administration to ovariectomized (Ovx) lab animals were recognized in multiple systems for years before clinical trials could adequately duplicate the results. Moreover, very large numbers of women are often needed to find statistically significant results in clinical trials of HT; and there are still opposing results being published, especially in neural and cardiovascular systems...
2017: PloS One
https://www.readbyqxmd.com/read/28628258/tankyrase-inhibition-regulates-corpus-luteum-development-and-luteal-function-in-gonadotropin-treated-rats
#4
Accialini Paula, Irusta Griselda, Bechis Andres, Bas Diana, Parborell Fernanda, Abramovich Dalhia, Tesone Marta
Tankyrases are physiological regulators of Axin, a protein involved in several cellular processes, including Wnt signaling. Here, we investigated the effect of a specific Tankyrase inhibitor (XAV939) in follicular-luteal dynamics, and its possible relationship with ovarian vascular development. Studies were designed to analyze the effect of intrabursa administration of XAV939 in gonadotropin-treated prepubertal rats. In particular, we examined follicle and corpus luteum development, steroidogenesis, angiogenic markers, and apoptotic parameters...
June 19, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28619359/postpartum-estrogen-withdrawal-impairs-gabaergic-inhibition-and-ltd-induction-in-basolateral-amygdala-complex-via-down-regulation-of-gpr30
#5
Rong Yang, Baofeng Zhang, Tingting Chen, Suyun Zhang, Ling Chen
Postpartum estrogen (E2) withdrawal is known to be a particularly vulnerable time for depressive symptoms. In this study, ovariectomized (OVX) mice were treated with co-administration of estradiol benzoate and progesterone (E2/P4) followed by administration of E2 alone (E2) and a subsequent E2 withdrawal (EW) to mimic the hormonal changes during pregnancy and postpartum. The objective of this study was to investigate the influence of E2 withdrawal after hormone-simulated pregnancy on synaptic function and plasticity in basolateral amygdala complex (BLA)...
June 13, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28608308/effect-of-reproductive-methods-and-gnrh-administration-on-long-term-protocol-in-santa-ines-ewes
#6
Marcos V Biehl, Marcos V C Ferraz Junior, Evandro M Ferreira, Daniel M Polizel, Alexandre A Miszura, José P R Barroso, Gabriela B Oliveira, Analisa V Bertoloni, Alexandre V Pires
This study aimed to determine whether reproductive performance of ewes submitted to laparoscopic timed artificial insemination (TAI) would be similar to ante meridiem (AM)/post meridiem (PM) rule and assisted natural mating (NM), and whether GnRH may enhance the pregnancy rate in TAI. In experiment I, 191 non-lactating ewes were synchronized, then TAI was performed either 48 h after progesterone (P4) removal (TAI-48 h) or 12 h after estrus detection (AM/PM); moreover, some ewes were submitted to NM (NM) as control treatment...
June 12, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28601161/effective-use-of-sexedultra%C3%A2-sex-sorted-semen-for-timed-artificial-insemination-of-beef-heifers
#7
J M Thomas, J W C Locke, R Vishwanath, J B Hall, M R Ellersieck, M F Smith, D J Patterson
An experiment was designed to evaluate the relative fertility of SexedULTRA(TM) sex-sorted semen compared to conventional, non-sex-sorted semen when used among beef heifers in conjunction with split-time AI following the 14-d CIDR-PG protocol. Units of conventional semen were generated with 25.0 × 10(6) live cells per 0.5 ml straw prior to freezing, and units of sex-sorted semen were generated using the SexedULTRA(TM) Genesis III sorting technology with 4.0 × 10(6) live cells per 0.25 ml straw prior to freezing...
August 2017: Theriogenology
https://www.readbyqxmd.com/read/28600619/ovarian-hyperstimulation-syndrome-following-gnrh-agonist-trigger-think-ectopic
#8
Raoul Orvieto, Valeria Stella Vanni
PURPOSE: This study aims to report a case of ovarian hyperstimulation syndrome (OHSS) following GnRH agonist trigger for final follicular maturation. METHODS: This study is a retrospective chart review. RESULTS: We report the first case of OHSS following GnRH agonist trigger for final follicular maturation and freeze-all, masking extrauterine pregnancy (EUP). The present case report elucidates the feasibility of stimulating and recruiting ovarian follicles yielding mature oocytes during early pregnancy and the ability of GnRH agonist to trigger final follicular maturation during pregnancy, in the presence of high progesterone and hCG levels...
June 9, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28596003/empty-follicle-syndrome-revisited-definition-incidence-aetiology-early-diagnosis-and-treatment
#9
REVIEW
Alberto Revelli, Andrea Carosso, Giuseppina Grassi, Gianluca Gennarelli, Stefano Canosa, Chiara Benedetto
In this review, the definition, incidence and possible causes of empty follicle syndrome (EFS), including molecular mechanisms that may underlie the syndrome, are discussed, along with prevention and treatment options. EFS is the complete failure to retrieve oocytes after ovarian stimulation, despite apparently normal follicle development and adequate follicular steroidogenesis. Two variants of EFS have been described: the 'genuine' form (gEFS), which occurs in the presence of adequate circulating HCG levels at the time of oocyte aspiration, and the 'false' form (f-EFS), which is associated with circulating HCG below a critical threshold...
May 23, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28595291/the-expression-of-cxcr4-is-induced-by-the-lh-surge-and-mediated-by-progesterone-receptors-in-human-preovulatory-granulosa-cells
#10
Yohan Choi, Ji Yeon Park, Kalin Wilson, Katherine L Rosewell, Mats Brännström, James W Akin, Thomas E Curry, Misung Jo
The chemokine CXC Motif Ligand 12 (CXCL12) and its cognate receptor, CXCR4, have been implicated in the ovulatory process in various animal models. However, little is known about the expression and regulation of CXCL12 and CXCR4 and their functions during the ovulatory period in the human ovary. In the present study, we characterized the expression patterns of CXCL12 and CXCR4 in preovulatory follicles collected before the LH surge and at defined hours after hCG administration in women with the regular menstrual cycle...
June 8, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28592693/non-genomic-actions-of-17-%C3%AE-estradiol-restore-respiratory-neuroplasticity-in-young-ovariectomized-female-rats
#11
Brendan J Dougherty, Elizabeth S Kopp, Jyoti J Watters
Gonadal steroids modulate CNS plasticity, including phrenic long-term facilitation (pLTF), a form of spinal respiratory neuroplasticity resulting in increased phrenic nerve motor output following exposure to acute intermittent hypoxia (aIH; three 5 min episodes, 10.5% O2). Despite the importance of respiratory system neuroplasticity, and its dependence on estrogen in males, little is known about pLTF expression or mechanisms of estrogen signaling in females. Here, we tested the hypotheses that: 1) pLTF expression in young, gonadally intact female rats would be expressed during estrous cycle stages in which 17β-estradiol (E2) is naturally high (e...
June 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28587385/gnrh-antagonist-for-patients-with-polycystic-ovary-syndrome-undergoing-controlled-ovarian-hyperstimulation-for-in-vitro-fertilization-and-embryo-transfer-in-fresh-cycles
#12
Xiang-Hong Zhai, Ping Zhang, Feng-Xia Wu, An-Cong Wang, Pei-Shu Liu
The aim of the present study was to evaluate the influence of a gonadotropin-releasing hormone (GnRH) antagonist compared with a GnRH agonist on the in vitro fertilization cycle outcome in patients with polycystic ovary syndrome. The outcomes of pregnancy were evaluated. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was also used to evaluate whether the endometrial thickness (cm) and estradiol (E2) level (pg/ml) on the day of human chorionic gonadotropin (hCG) administration (the hCG day) had the best sensitivity and specificity for predicting a clinical pregnancy...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28583600/administration-of-2-5%C3%A2-mg-of-estradiol-followed-by-1-500%C3%A2-mg-of-progesterone-to-anovulatory-mares-promote-similar-uterine-morphology-hormone-concentrations-and-molecular-dynamics-to-those-observed-in-cyclic-mares
#13
E S M Silva, F S Ignácio, S C Fritsch, D S Zanoni, J C F Pantoja, J P Oliveira-Filho, C Meira
To test the hypothesis that the administration of 2.5 mg of estradiol benzoate (EB) followed by 1500 mg of long acting progesterone (LA P4) causes similar uterine changes and molecular dynamics in anovulatory mares to those observed in cyclic ones, we evaluated the changes of estrogen (ERα and ERβ) and progesterone receptors (PR) in anestrous, transitional and cyclic mares by RT-qPCR and immunohistochemistry. In addition, we evaluated uterine edema, tonus and estrogens and progesterone plasma profile. Endometrial biopsies were taken from anestrous and transitional mares immediately before EB injection, 48 h after EB administration and five days after LA P4 was given...
July 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28551483/effect-of-growth-hormone-on-steroid-concentrations-and-mrna-expression-of-their-receptor-and-selected-egg-specific-protein-genes-in-the-chicken-oviduct-during-pause-in-laying-induced-by-fasting
#14
J K Socha, A Sechman, M Mika, A Hrabia
This study was undertaken to examine the effect of growth hormone (GH) treatment during pause in laying on (1) the concentration of steroids in blood plasma and oviduct tissues, (2) the expression of mRNA of steroid receptors, and (3) the mRNA expression of selected egg-specific proteins in the chicken oviduct. A pause in egg laying was induced by food deprivation for 5 d, followed by feeding every other day, and then feeding daily from Day 10 onward. Birds were divided into three groups: control (n = 18) fed ad libitum, subjected to pause in laying (n = 18), and subjected to pause in laying and injected every day with 200 μg/kg BW of chicken GH (chGH; n = 18)...
May 8, 2017: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/28544972/the-effect-of-elevated-progesterone-levels-before-oocyte-retrieval-in-women-undergoing-ovarian-stimulation-for-ivf-treatment-on-the-genomic-profile-of-peri-implantation-endometrium
#15
Liu Liu, Jin Huang, Tin Chiu Li, Xu Tao Hong, Susan Laird, Yong Dong Dai, Xiao Mei Tong, Hai Yan Zhu, Songying Zhang
To evaluate the effects of high progesterone prior to oocyte retrieval on the genomic profile of peri-implantation endometrium, we conducted this single-center, prospective cohort study. Depending on whether or not the progesterone level on the day of hCG administration and the day after hCG administration were elevated, a total of 20 women undergoing IVF treatment who did not have fresh embryo transfer were included: Group 1 refers to subjects with normal progesterone level on both days; Group 2 refers to subjects with normal progesterone level on the day of hCG administration and high progesterone level on the day after hCG administration; Group 3 refers to subjects with high progesterone level on the day of hCG administration and normal progesterone level on the day after hCG administration; Group 4 refers to subjects with high progesterone level on both days...
May 17, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/28532834/effects-of-feeding-green-microalgae-on-ovarian-activity-reproductive-hormones-and-metabolic-parameters-of-boer-goats-in-arid-subtropics
#16
W Senosy, A Y Kassab, A A Mohammed
The present study aimed to improve ovarian follicle development and plasma metabolites and hormone concentrations upon supplementation of Boer goats with green microalga (Dunaliella salina; 10 g/head/day) (N = 20; MAT group) compared to control (N = 10; not receive microalgae) in subtropics. Estrus was synchronized in all animals by two intramuscular administration of 12.5 mg dinoprost 11 days a part. MAT group was supplemented with Dunaliella salina for 11 days (from the day of first injection of dinoprost till the second injection)...
July 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28531369/should-high-bmi-be-a-reason-for-ivf-treatment-denial
#17
S Friedler, O Cohen, G Liberty, B Saar-Ryss, S Meltzer, T Lazer
Our aim was to examine the influence of BMI on the live-birth rate following IVF/ICSI and evaluate its specific contribution among other factors thus enabling accurate reproductive policy development. All patients that underwent IVF/ICSI at our center during January 2012-July 2015 were included in this retrospective study. A total of 1654 ICSI cycles were divided into four groups according to the patient's BMI (kg/m(2)): group I (normal weight): <25 (943 cycles); group II (overweight): 25-30 (403 cycles); group III (obese): 30-35 (212 cycles); group IV (morbid obesity): >35 (96 cycles)...
May 20, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28529269/possible-role-of-ppar%C3%AE-in-the-negative-regulation-of-ovulatory-cascade-and-luteal-development-in-rats
#18
Ryohei Funahashi, Takanobu Sakamoto, Norihito Taguchi, Ryosuke Naiki, Ryota Terashima, Mitsumori Kawaminami, Shiro Kurusu
Peroxisome proliferator-activated receptor γ (PPARγ), a member of a nuclear receptor family, has been shown to be implicated in various reproductive processes. Here, we evaluated possible roles of PPARγ in ovulation and luteal development in a gonadotropins-primed immature rat model. Immunoreactive PPARγ was expressed in granulosa cells of eCG-stimulated mature follicles, and its expression level decreased following ovulatory hCG stimulus. Intra-bursal treatment with rosiglitazone (a PPARγ agonist) simultaneously with subcutaneously administered hCG blocked the induction of cyclooxygenase-2 and steroidogenic acute regulatory protein (StAR) in preovulatory follicles...
May 19, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28527954/sex-differences-in-the-effect-of-chronic-mild-stress-on-mouse-prefrontal-cortical-bdnf-levels-a-role-of-major-ovarian-hormones
#19
Bhanu Chandra Karisetty, Pranav Chintamani Joshi, Arvind Kumar, Sumana Chakravarty
Depression induced by stress is affected by sex, age and hormonal status of the animal and also by duration and type of the stressors. Moreover, higher prevalence of depression and comorbidities in women than men implies the need to include the sex variable in studies on animal models of depression. The present study was therefore initiated to evaluate the effect of sex and ovarian hormones on depression-like phenotypes in mice exposed to a 21-day Chronic Variable Mild Stress (CVMS) paradigm. Adult male, intact female and, ovariectomized (OVX) female mice exposed to CVMS displayed despair behavior, a depression-like phenotype, in all the groups...
May 18, 2017: Neuroscience
https://www.readbyqxmd.com/read/28526975/lipid-nanoparticles-for-administration-of-poorly-water-soluble-neuroactive-drugs
#20
Elisabetta Esposito, Markus Drechsler, Paolo Mariani, Federica Carducci, Michela Servadio, Francesca Melancia, Patrizia Ratano, Patrizia Campolongo, Viviana Trezza, Rita Cortesi, Claudio Nastruzzi
This study describes the potential of solid lipid nanoparticles and nanostructured lipid carriers as nano-formulations to administer to the central nervous system poorly water soluble drugs. Different neuroactive drugs, i.e. dimethylfumarate, retinyl palmitate, progesterone and the endocannabinoid hydrolysis inhibitor URB597 have been studied. Lipid nanoparticles constituted of tristearin or tristearin in association with gliceryl monoolein were produced. The nanoencapsulation strategy allowed to obtain biocompatible and non-toxic vehicles, able to increase the solubility of the considered neuroactive drugs...
September 2017: Biomedical Microdevices
keyword
keyword
96291
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"