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https://www.readbyqxmd.com/read/28906315/development-of-the-aim-to-decrease-anxiety-and-pain-treatment-adapt-for-pediatric-functional-abdominal-pain-disorders
#1
Natoshia Raishevich Cunningham, Sarah Nelson, Anjana Jagpal, Erin Moorman, Michael Farrell, Scott Pentiuk, Susmita Kashikar-Zuck
OBJECTIVES: To evaluate the feasibility and acceptability of the Aim to Decrease Anxiety and Pain Treatment (ADAPT), a brief, on-line and in-person behavioral intervention targeting pain and anxiety in youth with functional abdominal pain disorders (FAPD). METHODS: Patients were recruited from several outpatient pediatric gastroenterology clinics. Nine participants (ages 9-13) completed the full protocol. Thematic analysis of detailed qualitative feedback was obtained via semi-structured patient and caregiver interviews after treatment was conducted...
September 12, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28879547/comparison-of-icd-9-codes-for-depression-and-alcohol-misuse-to-survey-instruments-suggests-these-codes-should-be-used-with-caution
#2
Joseph A Boscarino, Anne C Moorman, Loralee B Rupp, Yueren Zhou, Mei Lu, Eyasu H Teshale, Stuart C Gordon, Philip R Spradling, Mark A Schmidt, Connie Mah Trinacty, Yuna Zhong, Scott D Holmberg, Deborah Holtzman
BACKGROUND: Research suggests depression and alcohol misuse are highly prevalent among chronic hepatitis C (CHC) patients, which is of clinical concern. AIMS: To compare ICD-9 codes for depression and alcohol misuse to validated survey instruments. METHODS: Among CHC patients, we assessed how well electronic ICD-9 codes for depression and alcohol misuse predicted these disorders using validated instruments. RESULTS: Of 4874 patients surveyed, 56% were male and 52% had a history of injection drug use...
September 6, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28878012/synthetic-oligosaccharides-can-replace-animal-sourced-low-molecular-weight-heparins
#3
Yongmei Xu, Kasemsiri Chandarajoti, Xing Zhang, Vijayakanth Pagadala, Wenfang Dou, Debra Moorman Hoppensteadt, Erica M Sparkenbaugh, Brian Cooley, Sharon Daily, Nigel S Key, Diana Severynse-Stevens, Jawed Fareed, Robert J Linhardt, Rafal Pawlinski, Jian Liu
Low-molecular weight heparin (LMWH) is used clinically to treat clotting disorders. As an animal-sourced product, LMWH is a highly heterogeneous mixture, and its anticoagulant activity is not fully reversible by protamine. Furthermore, the reliability of the LMWH supply chain is a concern for regulatory agencies. We demonstrate the synthesis of heparin dodecasaccharides (12-mers) at the gram scale. In vitro experiments demonstrate that the anticoagulant activity of the 12-mers could be reversed using protamine...
September 6, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28876676/factors-contributing-to-elective-theatre-cancellations-in-the-department-of-surgery-at-chbah
#4
M Mulira, M D Smith, J Moorman
BACKGROUND: Elective theatre cancellations is a common experience the world over that impacts on theatre efficiency with undesirable consequences on the health care system, the patients and their families. It increases costs of running theatres, is a financial burden and emotional strain on patients and their families. METHOD: A retrospective study where 300 cancellations in the Department of Surgery were randomly selected and analysed from the Morbidity and Mortality meetings held at Chris Hani Baragwanath Academic Hospital from November 2015...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28871344/tubal-ligation-and-ovarian-cancer-risk-in-african-american-women
#5
Chrissy McNamara, Sarah E Abbott, Elisa V Bandera, Bo Qin, Lauren C Peres, Fabian Camacho, Patricia G Moorman, Anthony J Alberg, Jill S Barnholtz-Sloan, Melissa Bondy, Michele L Cote, Ellen Funkhouser, Edward S Peters, Ann G Schwartz, Joellen M Schildkraut, Paul Terry
PURPOSE: Tubal ligation has been associated with reduced risk of epithelial ovarian cancer (EOC) in studies of primarily white women, but less is known about the association in African American (AA) women. We sought to evaluate the associations among 597 invasive ovarian cancer cases and 742 controls of AA descent recruited from the African American Cancer Epidemiology Study, a population-based case-control study in 11 geographical areas in the US. METHODS: Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) adjusted for potentially confounding factors...
September 4, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28854391/monitoring-tylosin-and-sulfamethazine-in-a-tile-drained-agricultural-watershed-using-polar-organic-chemical-integrative-sampler-pocis
#6
Maurice T Washington, Thomas B Moorman, Michelle L Soupir, Mack Shelley, Amy J Morrow
This study evaluated the influence of temporal variation on the occurrence, fate, and transport of tylosin (TYL) and sulfamethazine (SMZ); antibiotics commonly used in swine production. Atrazine (ATZ) was used as a reference analyte to indicate the agricultural origin of the antibiotics. We also assessed the impact of season and hydrology on antibiotic concentrations. A reconnaissance study of the South Fork watershed of the Iowa River (SFIR), was conducted from 2013 to 2015. Tile drain effluent and surface water were monitored using polar organic integrative sampler (POCIS) technology...
August 27, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28847138/seasonal-variation-of-macrolide-resistance-gene-abundances-in-the-south-fork-iowa-river-watershed
#7
Elizabeth Luby Rieke, Thomas B Moorman, Elizabeth L Douglass, Michelle L Soupir
The Midwestern United States is dominated by agricultural production with high concentrations of swine, leading to application of swine manure onto lands with artificial subsurface drainage. Previous reports have indicated elevated levels of antibiotic resistance genes (ARGs) in surface water and groundwater around confined animal feeding operations which administer antimicrobials. While previous studies have examined the occurrence of ARGs around confined swine feeding operations, little information is known how their transport from tile-drained fields receiving swine manure application impacts downstream environments...
August 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28836848/evaluation-of-a-portable-media-device-for-use-in-determining-postural-stability-in-standing-horses
#8
Valerie J Moorman, Christopher E Kawcak, Melissa R King
OBJECTIVE To determine the ability of an accelerometer within a commercially available portable media device (PMD) to measure changes in postural stability of standing horses during various stance conditions and to compare these results with data obtained by use of a stationary force platform. ANIMALS 7 clinically normal horses. PROCEDURES A PMD was mounted on a surcingle; the surcingle was placed immediately caudal to the highest point of the shoulders (withers). Each horse was examined while standing on a stationary force platform system in a normal square stance, forelimb base-narrow stance, and normal square stance at 5 and 10 minutes after sedation induced by IV administration of xylazine hydrochloride...
September 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28836846/a-technique-of-needle-redirection-at-a-single-craniolateral-site-for-injection-of-three-compartments-of-the-equine-stifle-joint
#9
Meredith R A Herdrich, Shelby E Arrieta, Brad B Nelson, David D Frisbie, Valerie J Moorman
OBJECTIVE To determine accuracy for a technique of needle redirection at a single craniolateral site for injection of 3 compartments of the equine stifle joint, describe the external needle position, and identify the location of the needle tip within each joint compartment. SAMPLE 24 equine cadaver stifle joints. PROCEDURES Stifle joints were placed in a customized stand. After the needle was placed, external needle position was measured and recorded. Each joint compartment (medial and lateral compartments of the femorotibial joint and the femoropatellar joint) was injected with a solution containing iodinated contrast medium, water, and dye...
September 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28829244/using-clinical-signs-of-neglect-to-identify-elder-neglect-cases
#10
Lee S Friedman, Susan Avila, Elaine Liu, Kimberly Dixon, Olivia Patch, Renee Partida, Holly Zielke, Barbara Giloth, Daniel Friedman, Lois Moorman, Wendy Meltzer
Elder neglect is the one of the most pervasive forms of mistreatment and often the only place outside of the individual's residence to identify and assist neglected individuals is in a medical setting. However, elder neglect cases treated in hospitals do not present with a single diagnosis or clinical sign, but rather involve a complex constellation of clinical signs. Currently there is a lack of comprehensive guidelines on which clinical signs to use in screening tools for neglect among patients treated in hospitals...
August 22, 2017: Journal of Elder Abuse & Neglect
https://www.readbyqxmd.com/read/28789735/the-use-of-visual-thinking-strategies-and-art-to-help-nurses-find-their-voices
#11
Margaret Moorman
Health care is increasingly complex, as nurses navigate working in teams and conveying critical information to others. Clear communication and accuracy are critical for nurses because they communicate to patients and other members of the health care team. Art, and more specifically, Visual Thinking Strategies (VTS), are ways for nurses to practice communication and clear articulation of ideas. VTS also allows nurses to explore finding their voices and working with others to provide safe and effective communication among the team, including patients and their families...
August 1, 2017: Creative Nursing
https://www.readbyqxmd.com/read/28783781/plastic-biofilm-carrier-after-corn-cobs-reduces-nitrate-loading-in-laboratory-denitrifying-bioreactors
#12
Gary W Feyereisen, Laura E Christianson, Thomas B Moorman, Rodney T Venterea, Jeffrey A Coulter
Nitrate-nitrogen (nitrate-N) removal rates can be increased substantially in denitrifying bioreactors with a corn ( L.) cob bed medium compared with woodchips; however, additional organic carbon (C) is released into the effluent. This laboratory column experiment was conducted to test the performance of a postbed chamber of inert plastic biofilm carrier (PBC) after corn cobs (CC) to extend the area of biofilm colonization, enhance nitrate-N removal, lower total organic C losses, and reduce nitrous oxide (NO) production at warm (15...
July 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28771487/cardiorespiratory-dynamics-measured-from-continuous-ecg-monitoring-improves-detection-of-deterioration-in-acute-care-patients-a-retrospective-cohort-study
#13
Travis J Moss, Matthew T Clark, James Forrest Calland, Kyle B Enfield, John D Voss, Douglas E Lake, J Randall Moorman
BACKGROUND: Charted vital signs and laboratory results represent intermittent samples of a patient's dynamic physiologic state and have been used to calculate early warning scores to identify patients at risk of clinical deterioration. We hypothesized that the addition of cardiorespiratory dynamics measured from continuous electrocardiography (ECG) monitoring to intermittently sampled data improves the predictive validity of models trained to detect clinical deterioration prior to intensive care unit (ICU) transfer or unanticipated death...
2017: PloS One
https://www.readbyqxmd.com/read/28759694/doctorate-of-nursing-practice-students-impressions-of-uses-for-visual-thinking-strategies
#14
Desiree Hensel, Margaret Moorman
Visual Thinking Strategies (VTS) is a structured art-viewing technique designed to teach critical thinking and aesthetic appreciation. Literature on how VTS might be used in nursing is just emerging. This qualitative descriptive study examined written responses to how 14 doctorate of nursing practice students thought they might use VTS in their practice after engaging in a classroom session. Three themes emerged for how nurses might use VTS: Facilitating Interpersonal Relationships, Changing Thinking in Practice, and As a Teaching Tool...
August 1, 2017: Journal of Continuing Education in Nursing
https://www.readbyqxmd.com/read/28753742/stress-facilitates-the-development-of-cognitive-dysfunction-after-chronic-ethanol-exposure
#15
Ellen M Rodberg, Carolina R den Hartog, Rachel I Anderson, Howard C Becker, David E Moorman, Elena M Vazey
BACKGROUND: Chronic exposure to stress or alcohol can drive neuroadaptations that alter cognition. Alterations in cognition may contribute to alcohol use disorders by reducing cognitive control over drinking and maintenance of abstinence. Here we examined effects of combined ethanol (EtOH) and stress exposure on prefrontal cortex (PFC)-dependent cognition. METHODS: Adult male C57BL/6J mice were trained to drink EtOH (15%, v/v) on a 1 h/d 1-bottle schedule. Once stable, mice were exposed to cycles of chronic intermittent EtOH (CIE) or air-control vapor exposure (Air), followed by test cycles of 1 h/d EtOH drinking...
September 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28751678/morpho-functional-characterization-of-the-systemic-venous-pole-of-the-reptile-heart
#16
Bjarke Jensen, Signe Vesterskov, Bastiaan J Boukens, Jan M Nielsen, Antoon F M Moorman, Vincent M Christoffels, Tobias Wang
Mammals evolved from reptile-like ancestors, and while the mammalian heart is driven by a distinct sinus node, a sinus node is not apparent in reptiles. We characterized the myocardial systemic venous pole, the sinus venosus, in reptiles to identify the dominant pacemaker and to assess whether the sinus venosus remodels and adopts an atrium-like phenotype as observed in mammals. Anolis lizards had an extensive sinus venosus of myocardium expressing Tbx18. A small sub-population of cells encircling the sinuatrial junction expressed Isl1, Bmp2, Tbx3, and Hcn4, homologues of genes marking the mammalian sinus node...
July 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747508/mutations-in-the-e2-glycoprotein-and-the-3-untranslated-region-enhance-chikungunya-virus-virulence-in-mice
#17
David W Hawman, Kathryn S Carpentier, Julie M Fox, Nicholas A May, Wes Sanders, Stephanie A Montgomery, Nathaniel J Moorman, Michael S Diamond, Thomas E Morrison
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection. Although studies in humans and experimentally-infected animals suggest that CHIKV infection persists in musculoskeletal tissues, the mechanisms for this remain poorly understood. To evaluate this further, we isolated CHIKV from the serum of persistently infected Rag1(-/-) mice at day 28. When inoculated into naïve WT mice, this persistently circulating CHIKV strain displayed a capacity for earlier dissemination and greater pathogenicity compared with the parental virus...
July 26, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28737649/race-age-and-geography-impact-hepatitis-c-genotype-distribution-in-the-united-states
#18
Stuart C Gordon, Sheri Trudeau, Jia Li, Yueren Zhou, Loralee B Rupp, Scott D Holmberg, Anne C Moorman, Philip R Spradling, Eyasu Teshale, Joseph A Boscarino, Yihe G Daida, Mark A Schmidt, Mei Lu
GOALS: To determine the impact of geography and patient characteristics on hepatitis C virus (HCV) genotype and subtype distribution in a large sample of patients under routine clinical care BACKGROUND:: HCV genotype impacts disease course and response to treatment. Although several studies have reported genotype distribution within specific US populations, there are no comprehensive descriptions in large, geographically diverse cohorts. STUDY: Using data from the Chronic Hepatitis Cohort Study, we present the distribution of HCV genotypes (GT) and subtypes (ST) among a racially diverse cohort of over 8000 HCV-infected patients from four large US health systems...
July 21, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28684571/complete-genome-sequences-of-15-chikungunya-virus-isolates-from-puerto-rico
#19
Wes A Sanders, Kristin Long, Brenda Rivera, Heather A Vincent, Mark T Heise, Jose F Rodriguez-Orengo, Nathaniel J Moorman
Here, we report the complete genome sequences of 15 chikungunya virus strains isolated from human plasma from infected patients in Puerto Rico. The results show that currently circulating chikungunya strains in Puerto Rico are closely related.
July 6, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28671850/in-vivo-tibial-cartilage-strains-in-regions-of-cartilage-to-cartilage-contact-and-cartilage-to-meniscus-contact-in-response-to-walking
#20
Betty Liu, Nimit K Lad, Amber T Collins, Pramodh K Ganapathy, Gangadhar M Utturkar, Amy L McNulty, Charles E Spritzer, Claude T Moorman, E Grant Sutter, William E Garrett, Louis E DeFrate
BACKGROUND: There are currently limited human in vivo data characterizing the role of the meniscus in load distribution within the tibiofemoral joint. Purpose/Hypothesis: To compare the strains experienced in regions of articular cartilage covered by the meniscus to regions of cartilage not covered by the meniscus. We hypothesized that in response to walking, tibial cartilage covered by the meniscus would experience lower strains than uncovered tibial cartilage. STUDY DESIGN: Descriptive laboratory study...
June 1, 2017: American Journal of Sports Medicine
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