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https://www.readbyqxmd.com/read/28635643/a-multi-wavelength-opto-electronic-patch-sensor-to-effectively-detect-physiological-changes-against-human-skin-types
#1
Liangwen Yan, Sijung Hu, Abdullah Alzahrani, Samah Alharbi, Panagiotis Blanos
Different skin pigments among various ethnic group people have an impact on spectrometric illumination on skin surface. To effectively capture photoplethysmographic (PPG) signals, a multi-wavelength opto-electronic patch sensor (OEPS) together with a schematic architecture of electronics were developed to overcome the drawback of present PPG sensor. To perform a better in vivo physiological measurement against skin pigments, optimal illuminations in OEPS, whose wavelength is compatible with a specific skin type, were optimized to capture a reliable physiological sign of heart rate (HR)...
June 21, 2017: Biosensors
https://www.readbyqxmd.com/read/28631078/evaluation-of-the-association-between-sleep-apnea-and-polyunsaturated-fatty-acids-profiles-in-patients-after-percutaneous-coronary-intervention
#2
Keisuke Nakabayashi, Kentaro Jujo, Katsumi Saito, Toshiaki Oka, Nobuhisa Hagiwara
The long-term outcome is poor in patients with sleep apnea and cardiovascular disease. Polyunsaturated fatty acid (PUFA) is also known as an independent predictor for adverse clinical events. However, the profile of PUFA in sleep apnea patients with coronary artery disease (CAD) is still unclear. This study aimed to clarify the association between sleep apnea and PUFA profiles in patients with CAD. Two hundred seventy-four consecutive patients undergoing percutaneous coronary intervention (PCI) were screened for sleep apnea using nocturnal oximetry...
June 19, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28625550/maternal-exposure-to-western-diet-affects-adult-body-composition-and-voluntary-wheel-running-in-a-genotype-specific-manner-in-mice
#3
Layla Hiramatsu, Jarren Kay, Zoe Thompson, Jennifer Singleton, Gerald Claghorn, Ralph Lacerda de Albuquerque, Brittany Ho, Brett Ho, Gabriela Sanchez, Theodore Garland
Some human diseases, including obesity, Type II diabetes, and numerous cancers, are thought to be influenced by environments experienced in early life, including in utero. Maternal diet during the perinatal period may be especially important for adult offspring energy balance, potentially affecting both body composition and physical activity. This effect may be mediated by the genetic background of individuals, including, for example, potential "protective" mechanisms for individuals with inherently high levels of physical activity or high basal metabolic rates...
June 15, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28625260/-predictive-value-of-four-different-scoring-systems-for-septic-patient-s-outcome-a-retrospective-analysis-with-311-patients
#4
Shengbiao Wang, Tao Li, Yunfeng Li, Jianwen Zhang, Xingui Dai
OBJECTIVE: To study the predicting value of four different scoring systems such as the acute physiology and chronic health evaluation II (APACHE II) score, sequential organ failure assessment (SOFA) score, quick SOFA (qSOFA) score and systemic inflammatory response syndrome (SIRS) score for the prognosis of septic patients. METHODS: A retrospective analysis were conducted. Septic patients in intensive care unit (ICU) of the First People's Hospital of Chenzhou form July 1st, 2012 to June 30th, 2016 were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28624883/heart-rate-recovery-after-6-min-walking-test-predicts-acute-exacerbation-in-copd
#5
Diego A Rodríguez, Eleni A Kortianou, Jennifer A Alison, Alejandro Casas, Santiago Giavedoni, Anael Barberan-Garcia, Ane Arbillaga, Jordi Vilaró, Elena Gimeno-Santos, Ioannis Vogiatzis, Roberto Rabinovich, Josep Roca
INTRODUCTION: Abnormalities of autonomic function have been reported in patients with chronic obstructive pulmonary disease (COPD). Our objectives were to identify determinants of abnormal heart rate recovery at 1 min (HRR1) following completion of the 6-min walk test (6MWT) in COPD and to establish whether abnormal HRR1 predicts acute exacerbations (AECOPD). METHODS: Hundred one COPD patients (FEV1 (SD) 53 (19)  % predicted) were prospectively recruited in a multi-center study...
June 17, 2017: Lung
https://www.readbyqxmd.com/read/28624170/predictors-of-visit-to-visit-blood-pressure-variability-in-patients-with-hypertension-an-analysis-of-trials-with-an-amlodipine-treatment-arm
#6
Ji-Guang Wang, Duo Zhou, Barrett W Jeffers
We conducted a post hoc analysis of blood pressure (BP) data from long-term antihypertensive trials to identify predictors of visit-to-visit BP variability (BPV). BPV was defined as the within-subject coefficient of variation in systolic BP from week 12 onward. BP data from the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial, Comparison of Amlodipine Versus Enalapril to Limit Occurrences of Thrombosis, NY92011, and R-0510 trials were pooled and dichotomized into top 25th and bottom 75th percentiles because of positive skew...
May 29, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28624123/population-pharmacokinetic-pharmacodynamics-modeling-of-ibutilide-in-chinese-healthy-volunteers-and-patients-with-atrial-fibrillation-af-and-or-atrial-flutter-afl
#7
Zhijun Zeng, Li Wang, Lu Hua, Juanjuan Jiang, Huimin Pang, Yiling Huang, Yishi Li, Lei Tian
PURPOSE: The goal of this study was to develop a population pharmacokinetic (PK) and PK/pharmacodynamics (PD) model for ibutilide, to evaluate the time course of its effect on QT interval in Chinese. METHODS: The population PK and PK/PD model were developed using data from 40 Chinese healthy volunteers using nonlinear mixed-effects modeling, and the final population PK/PD model was applied on 100 patients with atrial fibrillation (AF) and/or atrial flutter (AFL)...
June 14, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28624095/fontan-circulation-over-time
#8
Djoeke Wolff, Joost P van Melle, Beatrijs Bartelds, Floris-Jan S Ridderbos, Graziella Eshuis, Elisabeth B H J van Stratum, Salvador J Recinos, Brigitte W M Willemse, Hans Hillege, Tineke P Willems, Tjark Ebels, Rolf M F Berger
The unique, unphysiological Fontan circulation is associated with an impaired functional status of the patients that is suggested to deteriorate over time. Unfortunately, previous studies did not integrate both pulmonary and cardiac determinants of functional status. In addition, a comparison with the natural decrease in exercise capacity in healthy subjects (in both children and adults) is lacking. This single-center study aims to investigate the functional status in a cohort of Fontan patients in relation to time since Fontan completion and to identify its determinants, including cardiac characteristics and pulmonary characteristics...
May 11, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28623982/clinical-characteristics-and-prognostic-features-of-intravenous-leiomyomatosis-with-inferior-vena-cava-or%C3%A2-intracardiac-extension
#9
Guorui Zhang, Xin Yu, Honghui Shi, Qingbo Fan, Jinghe Lang, Bao Liu
OBJECTIVE: The aim of this study was to explore the clinical characteristics and prognostic features of intravenous leiomyomatosis (IVL) with inferior vena cava extension (IVCE) or intracardiac extension (ICE). METHODS: A retrospective analysis was conducted of the clinical data of 38 patients with pathologically diagnosed IVL with IVCE or ICE. RESULTS: The mean age of the patients was 44.05 ± 6.31 years. Twenty-two patients (57.9%) had a history of uterine leiomyoma...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28622740/impact-of-a-pharmacist-managed-heart-failure-postdischarge-bridge-clinic-for-veterans
#10
Genevieve M Hale, Sonia L Hassan, Scott L Hummel, Carrie Lewis, David Ratz, Michael Brenner
BACKGROUND: Hospitals that provide early postdischarge follow-up after heart failure (HF) hospitalization tend to have lower rates of readmission. However, HF postdischarge (bridge) clinics have not been extensively evaluated. OBJECTIVE: To assess the impact of a pharmacist-managed HF bridge clinic in a veteran population. METHODS: HF patients hospitalized from November 2010 to August 2013 were identified. Retrospective chart review was conducted of 122 HF patients seen at bridge clinic compared with 122 randomly selected HF patients not seen at this clinic (usual care)...
July 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28620895/the-standardized-postoperative-checklist-for-bariatric-surgery-a-tool-for-safe-early-discharge
#11
Stefanie R van Mil, Lucia E Duinhouwer, Guido H H Mannaerts, L Ulas Biter, Martin Dunkelgrun, Jan A Apers
BACKGROUND: Morbidly obese patients are at higher risk of complications after surgery. In bariatric surgery, pre- and intra-operative checklists are commonly used to identify high-risk patients preoperatively, to decrease the number of postoperative complications. This pilot study evaluates the effect of a postoperative checklist in bariatric surgery, addressing regularly measured parameters, on the occurrence and early recognition of complications. METHODS: An in-house developed postoperative checklist was used on the first postoperative day after bariatric surgery and included information on nausea, pain, temperature, heart rate, and laboratory markers...
June 15, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28619703/identifying-nonclinical-factors-associated-with-30-day-readmission-in-patients-with-cardiovascular-disease-protocol-for-an-observational-study
#12
Matthew E Dupre, Alicia Nelson, Scott M Lynch, Bradi B Granger, Hanzhang Xu, Janese M Willis, Lesley H Curtis, Eric D Peterson
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of hospitalization in older adults and high readmission rates have attracted considerable attention as actionable targets to promote efficiency in care and to reduce costs. Despite a plethora of research over the past decade, current strategies to predict readmissions have been largely ineffective and efforts to identify novel clinical predictors have been largely unsuccessful. OBJECTIVE: The objective of this study is to examine a wide array of socioeconomic, psychosocial, behavioral, and clinical factors to predict risks of 30-day hospital readmission in cardiovascular patients...
June 15, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28618727/analysis-of-epidemiology-and-risk-factors-for-mortality-in-ventilator-associated-pneumonia-attacks-in-intensive-care-unit-patients
#13
Ayşe But, Meltem Arzu Yetkin, Dilek Kanyilmaz, Halide Aslaner, Aliye Baştuğ, Adalet Aypak, Pınar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hürrem Bodur
BACKGROUND/AIM: The aim of this study was to investigate the epidemiologic characteristics, the causative microorganisms and their antimicrobial susceptibility patterns, and the prognostic risk factors for mortality in critically ill patients with ventilator-associated pneumonia (VAP). MATERIALS AND METHODS: In this retrospective observational study, all the critically ill patients with VAP hospitalized in a medical/surgical intensive care unit (ICU) between January 2010 and June 2015 were evaluated...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28616545/assessment-of-various-parameters-using-simple-non-invasive-tests-in-patients-with-cardiovascular-diseases-with-or-without-cardiac-rehabilitation
#14
Takashi Ueda, Shin-Ichiro Miura, Kanta Fujimi, Toshihisa Ishida, Takuro Matsuda, Masaomi Fujita, Yoshiyuki Ura, Kouji Kaino, Maya Sakamoto, Tomoe Horita, Tadaaki Arimura, Yuhei Shiga, Takashi Kuwano, Ken Kitajima, Keijiro Saku
Cardiac rehabilitation (CR) improves cardiac function and exercise capacity in patients with cardiovascular disease (CVD). Simpler techniques are needed for use by physicians in the examination room to assess the usefulness of CR. We enrolled 46 consecutive CVD patients in a CR program (CR group) and prospectively followed them for 3 months. We compared them to 18 age-, gender- and body mass index-matched CVD patients without CR (non-CR group). Various parameters were measured at baseline and after 3 months using 3 simple non-invasive tests: severity of atherosclerosis [arterial velocity pulse index and arterial pressure volume index (API)] were determined using PASESA®, an autonomic nerve total activity amount index and a coefficient of variation of the R-R interval (CVRR) were determined using eHEART®, and peripheral resistance index, pressure rate product, stroke volume and cardiac index were determined using nico®]...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616394/new-method-of-sudomotor-function-measurement-to-detect-microvascular-disease-and-sweat-gland-nerve-or-unmyelinated-c-fiber-dysfunction-in-adults-with-retinopathy
#15
John E Lewis, Steven E Atlas, Ammar Rasul, Ashar Farooqi, Laura Lantigua, Oscar L Higuera, Andrea Fiallo, Lianette Laria, Renata Picciani, Ken Wals, Zohar Yehoshua, Armando Mendez, Janet Konefal, Sharon Goldberg, Judi Woolger
BACKGROUND: Diabetes-associated microvascular complications such as retinopathy and neuropathy often lead to end-organ and tissue damage. Impaired skin microcirculation often precedes the detection of other advanced diabetic complications. The ANS-1 system contains a redesigned sympathetic skin response (ANS-1 SSR) device that measures sudomotor function, a photoplethysmography sensor, and a blood pressure device to comprehensively assess cardiac autonomic neuropathy and endothelial dysfunction...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28615160/nkx2-5-is-essential-to-establish-normal-heart-rate-variability-in-the-zebrafish-embryo
#16
Jamie K Harrington, Robert Sorabella, Abigail Tercek, Joseph R Isler, Kimara L Targoff
Heart rate variability (HRV) has become an important clinical marker of cardiovascular health and a research measure for the study of the cardiac conduction system and its autonomic controls. While zebrafish (Danio rerio) is an ideal vertebrate model for understanding heart development, HRV has only recently been investigated in this system. We have previously demonstrated that nkx2.5 and nkx2.7, two homologues of Nkx2-5 expressed in zebrafish cardiomyocytes, play vital roles in maintaining cardiac chamber-specific characteristics...
June 14, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28612902/comparison-of-prognostic-values-of-cardiopulmonary-and-heart-rate-parameters-in-exercise-testing-in-men-with-heart-failure
#17
Łukasz Czubaszewski, Anna Straburzyńska-Lupa, Jacek Migaj, Ewa Straburzyńska-Migaj
BACKGROUND: Cardiopulmonary exercise testing (CPET) is the gold standard in the evaluation of patients with chronic heart failure (CHF). However, this test is relatively expensive, assessment of its results requires experience, and in Poland it is available only in tertiary health care centers. Many heart rate (HR) parameters taken during a standard electrocardiographic (ECG) exercise test also shows prognostic values. Thus, the aim of this study is to compare prognostic values of ventilatory and HR parameters in exercise testing in CHF patients, and to find out if HR parameters can be used instead of ventilatory in the evaluation of a prognosis...
June 14, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28611785/initiation-and-cessation-timing-of-renal-replacement-therapy-in-patients-with-type-1-cardiorenal-syndrome-an-observational-study
#18
Buyun Wu, Wenyan Yan, Xing Li, Xiangqing Kong, Xiangbao Yu, Yamei Zhu, Changying Xing, Huijuan Mao
BACKGROUND/AIMS: Renal replacement therapy (RRT) is a rescue therapy for patients with type 1 cardiorenal syndrome (CRS) with poor prognoses. However, the optimal timing for initiation and cessation of RRT remains controversial. The purpose of this study was to determine the optimal timing of initiation and cessation of RRT for patients with type 1 CRS. METHODS: In this retrospective analysis, patients with refractory type 1 CRS receiving RRT were divided into 3 groups according to weaning from RRT and death within 90 days...
February 2017: Cardiorenal Medicine
https://www.readbyqxmd.com/read/28610685/the-overweight-paradox-in-the-prognosis-of-acute-coronary-syndrome-for-patients-with-heart-failure-a-truth-for-all-a-10-year-follow-up-study
#19
Matina Kouvari, Christina Chrysohoou, Eleptherios Tsiamis, Hara Kosyfa, Lemonia Kalogirou, Androniki Filippou, Stelios Iosifidis, Panagiotis Aggelopoulos, Christos Pitsavos, Dimitris Tousoulis
OBJECTIVES: In established acute coronary syndrome (ACS) with major complications (i.e. heart failure), overweight/obese patients usually have a survival advantage. To what extent this is irrespective of other characteristics remains inconclusive. The role of body mass index (BMI) in ACS prognosis (fatal/recurrent non-fatal cardiac episodes) and background potential interactions were evaluated. STUDY DESIGN: In 2006-2009, 1000 consecutive patients, hospitalized at First Cardiology Clinic of Athens with a diagnosis of ACS were enrolled in the study...
August 2017: Maturitas
https://www.readbyqxmd.com/read/28610621/exploration-of-the-methodological-quality-and-clinical-usefulness-of-a-cross-sectional-sample-of-published-guidance-about-exercise-training-and-physical-activity-for-the-secondary-prevention-of-coronary-heart-disease
#20
Bridget Abell, Paul Glasziou, Tammy Hoffmann
BACKGROUND: Clinicians are encouraged to use guidelines to assist in providing evidence-based secondary prevention to patients with coronary heart disease. However, the expanding number of publications providing guidance about exercise training may confuse cardiac rehabilitation clinicians. We therefore sought to explore the number, scope, publication characteristics, methodological quality, and clinical usefulness of published exercise-based cardiac rehabilitation guidance. METHODS: We included publications recommending physical activity, exercise or cardiac rehabilitation for patients with coronary heart disease...
June 13, 2017: BMC Cardiovascular Disorders
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