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https://www.readbyqxmd.com/read/28238737/mortality-and-risk-of-dementia-in-normal-pressure-hydrocephalus-a%C3%A2-population-study
#1
Daniel Jaraj, Carsten Wikkelsø, Katrin Rabiei, Thomas Marlow, Christer Jensen, Svante Östling, Ingmar Skoog
INTRODUCTION: We examined mortality, dementia, and progression of hydrocephalic symptoms among untreated individuals with idiopathic normal-pressure hydrocephalus (iNPH) in a population-based sample. METHODS: A total of 1235 persons were examined between 1986 and 2012. Shunted individuals were excluded. We examined 53 persons with hydrocephalic ventricular enlargement (probable iNPH: n = 24, asymptomatic or possible iNPH: n = 29). Comparisons were made with individuals without hydrocephalic ventricular enlargement...
February 23, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28237772/factors-related-to-shunt-survival-in-paediatric-hydrocephalus-could-failure-be-avoided
#2
Sara Iglesias, Bienvenido Ros, Álvaro Martín, Antonio Carrasco, Miguel Segura, Angela Ros, Francisca Rius, Miguel Ángel Arráez
BACKGROUND: Improved shunt survival and a better understanding of factors related to failure in paediatric hydrocephalus still pose a challenge for neurosurgeons, in order to avoid morbidity and mortality, as well as the economic impact of repeated revision surgeries. For these reasons, an analysis is performed on the factors related to the first shunt failure in the long-term follow-up of a series in a single centre. METHODS: A retrospective review was conducted on 166 hydrocephalic paediatric patients shunted for the first time between 2000 and 2014...
February 22, 2017: Neurocirugía
https://www.readbyqxmd.com/read/28236064/the-disconnected-shunt-a-window-of-opportunities
#3
Jonathan Roth, Shlomi Constantini
INTRODUCTION: Shunt disconnection (SD), or migration of the distal end to extra-peritoneal tissues, may lead to shunt malfunction or be diagnosed incidentally. We present a systematic approach for treatment options that is tailored to each patient's personalized history, CSF physiology, and distribution (MRI), as well as a careful informed consent process. METHODS: We present two algorithms, for symptomatic and asymptomatic SD. In cases presenting with symptomatic elevated intracranial pressure, a distal shunt revision (DSR), or, in selected patients, an endoscopic third ventriculostomy (ETV), should be performed...
February 24, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28191353/alterations-in-cortical-thickness-and-white-matter-integrity-in-mild-to-moderate-communicating-hydrocephalic-school-aged-children-measured-by-whole-brain-cortical-thickness-mapping-and-dti
#4
Siyu Zhang, Xinjian Ye, Guanghui Bai, Yuchuan Fu, Chuanwan Mao, Aiqin Wu, Xiaozheng Liu, Zhihan Yan
Follow-up observation is required for mild-to-moderate hydrocephalic patients because of the potential damage to brain. However, effects of mild-to-moderate hydrocephalus on gray and white matter remain unclear in vivo. Using structural MRI and diffusion tensor imaging (DTI), current study compared the cortical thickness and white matter integrity between children with mild-to-moderate communicating hydrocephalus and healthy controls. The relationships between cortical changes and intelligence quota were also examined in patients...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28127723/obstructive-hydrocephalus-caused-by-an-unruptured-arteriovenous-malformation-successfully-treated-by-endoscopic-third-ventriculostomy-after-shunt-dysfunction
#5
Charles Champeaux, Céline Botella, Etienne Lefevre, Bertrand Devaux
The authors report on a patient harbouring an unruptured cortical arteriovenous malformation (AVM), who had presented with obstructive hydrocephalus due to compression of the cerebral aqueduct by a large venous varix. A ventriculoperitoneal (VP) shunt was inserted in emergency. Due to its large volume, the AVM was not referred for treatment and a follow-up policy was chosen. After the second VP shunt dysfunction, endoscopic third ventriculostomy was performed under neuronavigation. The procedure went uneventfully and the patient recovered well...
December 22, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28089808/stress-induced-hyperglycemia-after-spontaneous-subarachnoid-hemorrhage-and-its-role-in-predicting-cerebrospinal-fluid-diversion
#6
Bappaditya Ray, Ayumi Ludwig, Lori K Yearout, David M Thompson, Bradley N Bohnstedt
BACKGROUND: Stress induced hyperglycemia (SIH) after acute cerebrovascular disease is common and is associated with adverse clinical outcomes. Incidence of SIH after spontaneous subarachnoid hemorrhage (SAH) and its role in shunt placement has not been systematically investigated. Present study is designed to investigate the incidence of SIH after spontaneous SAH and its determinants. Role of SIH and premorbid hyperglycemia (using glycated hemoglobin, HbA1c) in predicting external ventricular drainage (EVD) and ventriculoperitoneal shunt (VPS) placement is also investigated...
January 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27988876/edaravone-reduces-astrogliosis-and-apoptosis-in-young-rats-with-kaolin-induced-hydrocephalus
#7
Camila Araújo Bernardino Garcia, Carlos Henrique Rocha Catalão, Hélio Rubens Machado, Ivair Matias Júnior, Thais Helena Romeiro, José Eduardo Peixoto-Santos, Marcelo Volpon Santos, Luiza da Silva Lopes
PURPOSE: We investigated the possible neuroprotective effects of the free radical scavenger edaravone in experimental hydrocephalus. METHODS: Seven-day-old Wistar rats were divided into three groups: control group (C), untreated hydrocephalic (H), and hydrocephalic treated with edaravone (EH). The H and EH groups were subjected to hydrocephalus induction by 20% kaolin intracisternal injection. The edaravone (20 mg/kg) was administered daily for 14 days from the induction of hydrocephalus...
December 17, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27878615/results-of-surgery-in-symptomatic-non-hydrocephalic-pineal-cysts-role-of-magnetic-resonance-imaging-biomarkers-indicative-of-central-venous-hypertension
#8
Per Kristian Eide, Geir Ringstad
BACKGROUND: We have previously proposed that pineal cysts (PCs) may result in crowding of the pineal recess, causing symptoms due to compression of the internal cerebral veins and central venous hypertension. In the present study, we compared clinical outcome of different treatment modalities in symptomatic individuals with non-hydrocephalic PCs. METHODS: The study included all patients managed surgically for non-hydrocephalic PCs in our Department of Neurosurgery over a 10-year period...
February 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27867930/a-case-of-primary-central-nervous-system-lymphoma-located-at-brain-stem-in-a-child
#9
Jinho Kim, Young Zoon Kim
Primary central nervous system lymphoma (PCNSL) is an extranodal Non-Hodgkin's lymphoma that is confined to the brain, eyes, and/or leptomeninges without evidence of a systemic primary tumor. Although the tumor can affect all age groups, it is rare in childhood; thus, its incidence and prognosis in children have not been well defined and the best treatment strategy remains unclear. A nine-year old presented at our department with complaints of diplopia, dizziness, dysarthria, and right side hemiparesis. Magnetic resonance image suggested a diffuse brain stem glioma with infiltration into the right cerebellar peduncle...
October 2016: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/27825904/ruptured-massa-intermedia-secondary-to-hydrocephalus
#10
Ahmed El Damaty, Soenke Langner, Henry W S Schroeder
BACKGROUND: We report a case of ruptured massa intermedia (MI) as a sequela of hydrocephalus. CASE DESCRIPTION: A single case report is presented describing the sequelae of tumor bed hematoma after a posterior fossa hemangioblastoma resection in which the patient bled 3 days after surgery, resulting in secondary hydrocephalus and subsequently dilatation of the third ventricle, which resulted in rupture of the MI. The patient was managed on emergency basis with an external ventricular drain then endoscopically with a third ventriculostomy and clot extraction...
January 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27766469/long-term-mortality-rates-in-pediatric-hydrocephalus-a-retrospective-single-center-study
#11
Matthias Gmeiner, Helga Wagner, Christoph Zacherl, Petra Polanski, Christian Auer, Willem J R van Ouwerkerk, Kurt Holl
PURPOSE: Very long-term follow-up and outcome are rare for pediatric patients with hydrocephalus and shunt operations. The aim of this study was to determine the long-term mortality rates in these patients. METHODS: Pediatric patients with first shunt operation between 1982 and 1992 were included. For each patient, time and cause of death were determined. Further, patients with first operation from 1982 to 1987 were compared to those first operated from 1988 to 1992...
October 20, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27684061/influence-of-the-state-of-the-subarachnoid-space-of-the-cranial-base-in-hydrocephalus-resolution-after-endoscopy
#12
Jose Juan Sanchez Rodriguez, Jaime Torres Corzo, Dominic Shelby Cervantes, Roberto Rodriguez-DellaVecchia, Antonio Gordillo-Moscoso, Juan Manuel Vinas Rios, Martin Sanchez-Aguilar
Objective To compare the resolution rate of hydrocephalus after endoscopy (predominantly endoscopic third ventriculostomy [ETV]) using flexible endoscopes during a 5-year period in patients with a permeable and a nonpermeable subarachnoid space (SAS). Material and Methods We conducted a retrospective cohort study of the videos and records of 150 hydrocephalic patients chosen randomly who underwent ETV (and other endoscopic procedures) with a flexible endoscope. The patients were classified into two groups based on the neuroendoscopic findings...
September 29, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27645624/ep01-04-v-mode-and-b-mode-in-differential-diagnosis-among-hydrocephalic-persistent-blake-s-pouch-non-hdc-persistent-blake-s-pouch-and-dandy-walker-complex
#13
E Varvarigos, M Iaccarino, S Iaccarino, M La Verde, V Parisella, R N Laurini
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27515195/a-unifying-hypothesis-for-hydrocephalus-and-the-chiari-malformations-part-two-the-hydrocephalus-filling-mechanism
#14
Helen Williams
It is proposed that negative central nervous system (CNS) pressure is one of the filling mechanisms of the fluid spaces of the CNS. Negative CNS pressure is caused by the combination of gravitational force and body movement. The venous system imposes pressure fluctuations on the CNS due to changes in posture and body cavity pressure. It is proposed here that filling of veins, arteries and cerebrospinal (CSF) spaces are all assisted by negative CNS pressure. Hyperemia in the CNS in response to pressure changes with movement was described in the first part of this hypothesis...
September 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27490332/does-ventriculoperitoneal-shunting-improve-thyroid-hormone-levels-in-hydrocephalic-newborns
#15
Necati Ucler, Fatih Serhat Erol, Sait Ozturk, Bekir Akgun, Metin Kaplan, Yasar Sen
OBJECTIVE/AIM: The aim of this report was to investigate the effect of ventriculoperitoneal shunt insertion for the treatment of hydrocephalus on thyroid hormones in the first 3 months of life. METHODS: Thyroid-stimulating hormone (TSH), free T3 (fT3), and free T4 (fT4) levels were compared at 7 days (preoperatively) and at 30 and 90 days (postoperatively) after birth between 25 ventriculoperitoneal shunt-inserted hydrocephalic newborns and 20 healthy newborns. RESULTS: The TSH level at 7 days was higher in the hydrocephalic patient group (6...
2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27423599/increased-pulsatile-intracranial-pressure-in-patients-with-symptomatic-pineal-cysts-and-magnetic-resonance-imaging-biomarkers-indicative-of-central-venous-hypertension
#16
Per Kristian Eide, Geir Ringstad
BACKGROUND: In symptomatic individuals with non-hydrocephalic pineal cysts (PCs), it remains controversial what causes the symptoms. Based on magnetic resonance imaging (MRI) biomarkers, we proposed that PC-associated crowding of the pineal recess may cause central venous hypertension. The aim of this study was to compare pulsatile and static ICP in patients with PCs and chronic daily headache (CDH), and compare ICP data in PC patients with the previously identified MRI biomarkers. METHODS: All patients assessed with over-night ICP monitoring for PCs or CDH who had been ruled out for idiopathic intracranial hypertension without papilledema (IIHWOP) were retrieved from the database...
August 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27314540/endoscopic-treatment-of-suprasellar-cysts-without-hydrocephalus
#17
Song-Bai Gui, Sheng-Yuan Yu, Lei Cao, Ji-Wei Bai, Xin-Sheng Wang, Chu-Zhong Li, Ya-Zhuo Zhang
OBJECTIVE At present, endoscopic treatment is advised as the first procedure in cases of suprasellar arachnoid cysts (SSCs) with hydrocephalus. However, the appropriate therapy for SSCs without hydrocephalus has not been fully determined yet because such cases are very rare and because it is usually difficult to perform the neuroendoscopic procedure in patients without ventriculomegaly given difficulties with ventricular cannulation and the narrow foramen of Monro. The purpose of this study was to find out the value of navigation-guided neuroendoscopic ventriculocystocisternostomy (VCC) for SSCs without lateral ventriculomegaly...
October 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27294849/neonatal-hydrocephalus-is-a-result-of-a-block-in%C3%A2-folate-handling-and-metabolism-involving-10-formyltetrahydrofolate-dehydrogenase
#18
Naila Naz, Alicia Requena Jimenez, Anna Sanjuan-Vilaplana, Megan Gurney, Jaleel Miyan
Folate is vital in a range of biological processes and folate deficiency is associated with neurodevelopmental disorders such as neural tube defects and hydrocephalus (HC). 10-formyl-tetrahydrofolate-dehydrogenase (FDH) is a key regulator for folate availability and metabolic interconversion for the supply of 1-carbon groups. In previous studies, we found a deficiency of FDH in CSF associated with the developmental deficit in congenital and neonatal HC. In this study, we therefore aimed to investigate the role of FDH in folate transport and metabolism during the brain development of the congenital hydrocephalic Texas (H-Tx) rat and normal (Sprague-Dawley) rats...
August 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27185652/implementing-routine-head-circumference-measurements-in-addis-ababa-ethiopia-means-and-challenges
#19
Arvid A Eriksen, Joakim S Johnsen, Anders H Tennøe, Abenezer Tirsit, Tsegazeab Laeke, Ephrem B Amare, Knut Wester
OBJECTIVE: A substantial number of infants in Ethiopia suffer from hydrocephalus. Neurosurgical expertise has until recently been virtually nonexistent in the country; however, since 2006, a neurosurgery training program has been established in Addis Ababa, where hydrocephalus surgery now is performed in 3 hospitals. Our experience is that hydrocephalus is diagnosed and treatment is too late to avoid severe brain damage. Introducing routine head circumference (HC) measurements can ease the detection of hydrocephalus and thus lead to earlier diagnosis, thereby reducing the brain damage caused by the condition...
July 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27177735/female-gender-predisposes-for-cerebrospinal-fluid-overdrainage-in-ventriculoperitoneal-shunting
#20
Naïma Diesner, Florian Freimann, Christin Clajus, Kai Kallenberg, Veit Rohde, Florian Stockhammer
BACKGROUND: Gravitational valves (GVs) prevent overdrainage in ventriculoperitoneal shunting (VPS). However, there are no data available on the appropriate opening pressure in the shunt system when implementing a GV. We performed a retrospective analysis of hydrocephalic patients who were successfully treated with VPS which included one or more GV. METHOD: In this retrospective study in adult VPS patients with GVs, we analysed all available data, including the most recent computed tomography (CT) scans, to determine the best adjustments for alleviating any symptoms of overdrainage and underdrainage...
July 2016: Acta Neurochirurgica
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