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L Debeljuk, R Perez, H Kaskal, R Rozados
The effect of Quinestrol, an estrogenic substance of long-lasting activity, on the pituitary responsiveness to LH-RH was studied in ovariectomized rats. Quinestrol administered as a single 200 pg-dose significantly augmented the pituitary response to LH-RH 36 hr, 9 days, and although not significantly, also at 24 days after its oral administration. No effect could be detected 36 days after its administration. At a 20 pg-dose Quinestrol significantly augmented the pituitary response to LH-RH only at the 36 hr-period studied, this effect not being apparent in later time periods...
February 1975: Proceedings of the Society for Experimental Biology and Medicine
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