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MR perfusion

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https://www.readbyqxmd.com/read/28914874/-craniofacial-tumors-blood-supply
#1
Yu G Yakovlenko, V A Cherekaev, V N Kornienko, I N Pronin, L V Shishkina, A S Tonoyan, E I Shul'tz, A M Parshunina
Because of the spread to different anatomical regions, craniofacial tumors (CFTs) usually receive blood supply from several arterial systems, and CFT removal is often accompanied by abundant blood loss. PURPOSE: The study purpose was to develop an algorithm of diagnostic angiography for planning surgical treatment of CFT patients. MATERIAL AND METHODS: Complex preoperative angiography was performed in 72 patients with craniofacial tumors, aged 10 to 78 years (mean age, 45...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28913838/simultaneous-acquisition-of-perfusion-image-and-dynamic-mr-angiography-using-time-encoded-pseudo-continuous-asl
#2
Yuriko Suzuki, Michael Helle, Peter Koken, Marc Van Cauteren, Matthias J P van Osch
PURPOSE: Both dynamic magnetic resonance angiography (4D-MRA) and perfusion imaging can be acquired by using arterial spin labeling (ASL). While 4D-MRA highlights large vessel pathology, such as stenosis or collateral blood flow patterns, perfusion imaging provides information on the microvascular status. Therefore, a complete picture of the cerebral hemodynamic condition could be obtained by combining the two techniques. Here, we propose a novel technique for simultaneous acquisition of 4D-MRA and perfusion imaging using time-encoded pseudo-continuous arterial spin labeling...
September 14, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28912536/predictive-and-prognostic-value-of-intravoxel-incoherent-motion-ivim-mr-imaging-in-patients-with-advanced-cervical-cancers-undergoing-concurrent-chemo-radiotherapy
#3
Li Zhu, Huanhuan Wang, Lijing Zhu, Jie Meng, Yan Xu, Baorui Liu, Weibo Chen, Jian He, Zhengyang Zhou, Xiaofeng Yang
By using the intravoxel incoherent motion (IVIM) model, the diffusion-related coefficient (D) and the perfusion-related parameter (f) can be obtained simultaneously. Here, we explored the application of IVIM MR imaging in predicting long-term prognosis in patients with advanced cervical cancers treated with concurrent chemo-radiotherapy (CCRT). In this study, pelvic MR examinations including an IVIM sequence were performed on 30 women with advanced cervical cancers at three time points (within 2 weeks before, as well as 2 and 4 weeks after, the initiation of CCRT)...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912284/t1-weighted-dynamic-contrast-enhanced-mr-perfusion-imaging-characterizes-tumor-response-to-radiation-therapy-in-chordoma
#4
P Santos, K K Peck, J Arevalo-Perez, S Karimi, E Lis, Y Yamada, A I Holodny, J Lyo
BACKGROUND AND PURPOSE: Chordomas notoriously demonstrate a paucity of changes following radiation therapy on conventional MR imaging. We hypothesized that dynamic contrast-enhanced MR perfusion imaging parameters of chordomas would change significantly following radiation therapy. MATERIALS AND METHODS: Eleven patients with pathology-proved chordoma who completed dynamic contrast-enhanced MR perfusion imaging pre- and postradiation therapy were enrolled. Quantitative tumor measurements were obtained by 2 attending neuroradiologists...
September 14, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28894884/characterization-of-skull-base-lesions-using-pseudo-continuous-arterial-spin-labeling
#5
B Geerts, D Leclercq, S Tezenas du Montcel, B Law-Ye, S Gerber, D Bernardeschi, D Galanaud, D Dormont, N Pyatigorskaya
PURPOSE: Pseudo-continuous arterial spin labeling (pCASL) is a non-invasive magnetic resonance (MR) perfusion technique. Our study aimed at estimating the diagnostic performance of the pCASL sequence in assessing the perfusion of skull base lesions both qualitatively and quantitatively and at providing cut-off values for differentiation of specific skull base lesions. METHODS: In this study 99 patients with histopathologically confirmed skull base lesions were retrospectively enrolled...
September 11, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28892580/correlation-of-quantitative-parameters-of-magnetic-resonance-perfusion-weighted-imaging-with-vascular-endothelial-growth-factor-microvessel-density-and-hypoxia-inducible-factor-1%C3%AE-in-nasopharyngeal-carcinoma-evaluation-on-radiosensitivity-study
#6
Ying Hu, Hong E, Xiaoping Yu, Feiping Li, Longwu Zeng, Qiang Lu, Xuping Xi, Liangfang Shen
OBJECTIVES: To investigate the correlation of parameters of magnetic resonance perfusion-weighted imaging (MR-PWI) with the expression of vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1α (HIF-1α) and microvessel density (MVD) in nasopharyngeal carcinoma (NPC) so as to explore the value of predicting radiosensitivity. DESIGN: A prospective study. SETTING: Department of Head-and-neck radiotherapy in Hunan Cancer Hospital...
September 11, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28889246/the-preliminary-radiogenomics-association-between-mr-perfusion-imaging-parameters-and-genomic-biomarkers-and-their-predictive-performance-of-overall-survival-in-patients-with-glioblastoma
#7
Xiang Liu, Rajiv Mangla, Wei Tian, Xing Qiu, Dongmei Li, Kevin A Walter, Sven Ekholm, Mahlon D Johnson
The radiogenomics association of neovascularization is important for overall survival (OS) in glioblastoma patients and remains unclear. The purpose of this study is to assess the association between MR perfusion imaging derived parameters and genomic biomarkers of glioblastoma, and to evaluate their prognostic value. This retrospective study enrolled 41 patients with newly diagnosed glioblastoma. The mean and maximal relative cerebral blood volume (rCBV) ratio (rCBVmean and rCBVmax), derived from MR perfusion weighted imaging, of the enhancing tumor, as well as maximal rCBV ratio of peri-enhancing tumor area (rCBVperi-tumor) were measured...
September 9, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28885745/intravoxel-incoherent-motion-mri-as-a-means-to-measure-in-vivo-perfusion-a-review-of-the-evidence
#8
REVIEW
Christian Federau
The idea that in vivo intravoxel incoherent motion magnetic resonance signal is influenced by blood motion in the microvasculature is exciting, because it suggests that local and quantitative perfusion information can be obtained in a simple and elegant way from a few diffusion-weighted images, without contrast injection. When the method was proposed in the late 1980s some doubts appeared as to its feasibility, and, probably because the signal to noise and image quality at the time was not sufficient, no obvious experimental evidence could be produced to alleviate them...
September 8, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28885324/the-application-of-high-field-magnetic-resonance-perfusion-imaging-in-the-diagnosis-of-pancreatic-cancer
#9
Shufang Yang, Heping Zhang, Xuequn Ren
Pancreatic cancer is the fourth leading cause of cancer death in the world. It is a disease of insidious progression and high lethality. The present study was to investigate the diagnostic value of high-filed magnetic resonance (MR) perfusion imaging in pancreatic cancer. Thirty-three patients with suspected pancreatic cancer were recruited in our study and underwent routine MR imaging. When compared with para-tumoral and normal tissue, the pancreatic lesions showed significant lower slope, peak enhancement (PE), and signal enhancement ratio (SER) as well as higher time to peak (TTP)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28884300/what-every-radiologist-should-know-about-adnexal-torsion
#10
Guillaume Ssi-Yan-Kai, Anne-Laure Rivain, Caroline Trichot, Marie-Chantal Morcelet, Sophie Prevot, Xavier Deffieux, Jocelyne De Laveaucoupet
Adnexal torsion is the fifth most common gynecologic surgical emergency, requiring clinician and radiologist awareness. It involves the rotation of the ovarian tissue on its vascular pedicle leading to stromal edema, hemorrhagic infarction, and necrosis of the adnexal structures with the subsequent sequelae. Expedient diagnosis poses a difficult challenge because the clinical presentation is variable and often misleading. Adnexal torsion can mimic malignancy as it can take a subacute, intermittent, or chronic course, and thereby can be complicated to diagnose...
September 7, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28882603/gamma-knife-surgery-for-a-hemangioma-of-the-cavernous-sinus-in-an-adult-case-report-and-short-review-of-the-literature
#11
L Schwyzer, C Tuleasca, F-X Borruat, I Radovanovic, M Levivier
Cavernous sinus hemangiomas (CSH) are rare benign extra-axial vascular lesions. Both radiological and clinical aspects are important, for deciding a therapeutic modality, including medical treatment, radiation therapy or microsurgery. In the particular case of CSH, a radical removal of the tumor often cannot be achieved and is associated with a considerable risk for intraoperative uncontrollable bleeding. An alternative treatment modality is radiosurgery. Here we report the case of a 45-year-old patient, who presented with diplopia due to left abducens nerve palsy...
September 4, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28881847/to-predict-the-radiosensitivity-of-nasopharyngeal-carcinoma-using-intravoxel-incoherent-motion-mri-at-3-0-t
#12
Wen Bo Chen, Bin Zhang, Long Liang, Yu Hao Dong, Guan Hui Cai, Chang Hong Liang, Bo Wen Lan, Shui Xing Zhang
PURPOSE: To investigate intravoxel incoherent motion (IVIM) MRI for evaluating the sensitivity of radiotherapy on nasopharyngeal carcinoma (NPC). RESULTS: The reproducibility between intra-observer and inter-observer was relatively good. D (0.72×10(-3) mm(2)/s±0.14 vs. 0.54×10(-3) mm(2)/s±0.23; P < 0.001) and D* (157.92×10(-3) mm(2)/s±15.21 vs. 120.36×10(-3) mm(2)/s±10.22; P < 0.0001) were significantly higher in effective group than poor-effective group, whereas the difference of f (18...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879895/perfusion-mr-imaging-of-enhancing-brain-tumors-comparison-of-arterial-spin-labeling-technique-with-dynamic-susceptibility-contrast-technique
#13
Neetu Soni, Devender Pal S Dhanota, Sunil Kumar, Awadhesh K Jaiswal, Arun K Srivastava
OBJECTIVE: Arterial spin labeling (ASL) magnetic resonance (MR) perfusion is a noninvasive and repeatable method for quantitatively measuring cerebral blood flow (CBF). This study aims to compare measurements of ASL-derived CBF with dynamic susceptibility contrast (DSC) MRI in the assessment of enhancing brain tumors (primary and metastatic), with an aim to use ASL as an alternative to DSC. MATERIALS AND METHODS: Thirty patients with newly diagnosed brain tumors (16 meningiomas, 6 gliomas, 3 metastases, 2 cerebellopontine angle schwannoma, 1 central neurocytoma, and 2 low-grade gliomas) were examined using a 3T MR scanner...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28879406/whole-tumor-histogram-analysis-of-the-cerebral-blood-volume-map-tumor-volume-defined-by-11c-methionine-positron-emission-tomography-image-improves-the-diagnostic-accuracy-of-cerebral-glioma-grading
#14
Rongli Wu, Yoshiyuki Watanabe, Atsuko Arisawa, Hiroto Takahashi, Hisashi Tanaka, Yasunori Fujimoto, Tadashi Watabe, Kayako Isohashi, Jun Hatazawa, Noriyuki Tomiyama
PURPOSE: This study aimed to compare the tumor volume definition using conventional magnetic resonance (MR) and 11C-methionine positron emission tomography (MET/PET) images in the differentiation of the pre-operative glioma grade by using whole-tumor histogram analysis of normalized cerebral blood volume (nCBV) maps. MATERIALS AND METHODS: Thirty-four patients with histopathologically proven primary brain low-grade gliomas (n = 15) and high-grade gliomas (n = 19) underwent pre-operative or pre-biopsy MET/PET, fluid-attenuated inversion recovery, dynamic susceptibility contrast perfusion-weighted magnetic resonance imaging, and contrast-enhanced T1-weighted at 3...
September 6, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28864020/pre-clinical-evaluation-of-a-nanoparticle-based-blood-pool-contrast-agent-for-mr-imaging-of-the-placenta
#15
Ketan B Ghaghada, Zbigniew A Starosolski, Saakshi Bhayana, Igor Stupin, Chandreshkumar V Patel, Rohan C Bhavane, Haijun Gao, Andrey Bednov, Chandrasekhar Yallampalli, Michael Belfort, Verghese George, Ananth V Annapragada
INTRODUCTION: Non-invasive 3D imaging that enables clear visualization of placental margins is of interest in the accurate diagnosis of placental pathologies. This study investigated if contrast-enhanced MRI performed using a liposomal gadolinium blood-pool contrast agent (liposomal-Gd) enables clear visualization of the placental margins and the placental-myometrial interface (retroplacental space). Non-contrast MRI and contrast-enhanced MRI using a clinically approved conventional contrast agent were used as comparators...
September 2017: Placenta
https://www.readbyqxmd.com/read/28861622/perfusion-magnetic-resonance-imaging-in-pediatric-brain-tumors
#16
F Dallery, R Bouzerar, D Michel, C Attencourt, V Promelle, J Peltier, J M Constans, O Balédent, C Gondry-Jouet
PURPOSE: The use of DSC-MR imaging in pediatric neuroradiology is gradually growing. However, the number of studies listed in the literature remains limited. We propose to assess the perfusion and permeability parameters in pediatric brain tumor grading. METHODS: Thirty children with a brain tumor having benefited from a DSC-MR perfusion sequence have been retrospectively explored. Relative CBF and CBV were computed on the ROI with the largest lesion coverage. Assessment of the lesion's permeability was also performed through the semi-quantitative PSR parameter and the K2 model-based parameter on the whole-lesion ROI and a reduced ROI drawn on the permeability maps...
August 31, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28860608/fmiso-pet-derived-brain-oxygen-tension-maps-application-to-glioblastoma-and-less-aggressive-gliomas
#17
Ararat Chakhoyan, Jean-Sebastien Guillamo, Solène Collet, François Kauffmann, Nicolas Delcroix, Emmanuèle Lechapt-Zalcman, Jean-Marc Constans, Edwige Petit, Eric T MacKenzie, Louisa Barré, Myriam Bernaudin, Omar Touzani, Samuel Valable
Quantitative imaging modalities for the analysis of hypoxia in brain tumors are lacking. The objective of this study was to generate absolute maps of tissue ptO2 from [(18)F]-FMISO images in glioblastoma and less aggressive glioma patients in order to quantitatively assess tumor hypoxia. An ancillary objective was to compare estimated ptO2 values to other biomarkers: perfusion weighted imaging (PWI) and tumor metabolism obtained from (1)H-MR mono-voxel spectroscopy (MRS). Ten patients with glioblastoma (GBM) and three patients with less aggressive glioma (nGBM) were enrolled...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28860216/arterial-spin-labeling-perfusion-mr-imaging-demonstrates-regional-cbf-decrease-in-idiopathic-normal-pressure-hydrocephalus
#18
J Virhammar, K Laurell, A Ahlgren, E-M Larsson
BACKGROUND AND PURPOSE: Regional cerebral blood flow has previously been studied in patients with idiopathic normal pressure hydrocephalus with imaging methods that require an intravenous contrast agent or expose the patient to ionizing radiation. The purpose of this study was to assess regional CBF in patients with idiopathic normal pressure hydrocephalus compared with healthy controls using the noninvasive quantitative arterial spin-labeling MR imaging technique. A secondary aim was to compare the correlation between symptom severity and CBF...
August 31, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28858563/imaging-human-brain-perfusion-with-inhaled-hyperpolarized-129-xe-mr-imaging
#19
Madhwesha R Rao, Neil J Stewart, Paul D Griffiths, Graham Norquay, Jim M Wild
Purpose To evaluate the feasibility of directly imaging perfusion of human brain tissue by using magnetic resonance (MR) imaging with inhaled hyperpolarized xenon 129 ((129)Xe). Materials and Methods In vivo imaging with (129)Xe was performed in three healthy participants. The combination of a high-yield spin-exchange optical pumping (129)Xe polarizer, custom-built radiofrequency coils, and an optimized gradient-echo MR imaging protocol was used to achieve signal sensitivity sufficient to directly image hyperpolarized (129)Xe dissolved in the human brain...
August 31, 2017: Radiology
https://www.readbyqxmd.com/read/28856718/tomoelastography-of-the-native-kidney-regional-variation-and-physiological-effects-on-in-vivo-renal-stiffness
#20
Stephan Rodrigo Marticorena Garcia, Markus Grossmann, Sophia Theresa Lang, Heiko Tzschätzsch, Florian Dittmann, Bernd Hamm, Jürgen Braun, Jing Guo, Ingolf Sack
PURPOSE: To measure normal renal stiffness in adults, taking into account regional variation, hydration, and urinary status. METHODS: Thirty-six healthy volunteers were examined by tomoelastography based on MR elastography at four frequencies, from 40 to 70 Hz and multifrequency shear wave speed recovery. Regional wave speeds were derived for the medulla, cortex (inner cortex and outer cortex), and renal pelvis, and examined for age-related effects. Subgroups were repeatedly examined for reproducibility, amount of prior water drinking, and urinary status...
August 30, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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