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cervical degenerative disc disease

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https://www.readbyqxmd.com/read/29069048/predictive-factors-associated-with-neck-pain-in-patients-with-cervical-disc-degeneration-a-cross-sectional-study-focusing-on-modic-changes
#1
Lingde Kong, Weifeng Tian, Peng Cao, Haonan Wang, Bing Zhang, Yong Shen
The predictive factors associated with neck pain remain unclear. We conducted a cross-sectional study to assess predictive factors, especially Modic changes (MCs), associated with the intensity and duration of neck pain in patients with cervical disc degenerative disease.We retrospectively reviewed patients in our hospital from January 2013 to December 2016. Severe neck pain (SNP) and persistent neck pain (PNP) were the 2 main outcomes, and were assessed based on the numerical rating scale (NRS). Basic data, and also imaging data, were collected and analyzed as potential predictive factors...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29057356/anterior-cervical-spine-surgery-associated-complications-in-a-retrospective-case-control-study
#2
REVIEW
Anastasia Tasiou, Theofanis Giannis, Alexandros G Brotis, Ioannis Siasios, Iordanis Georgiadis, Haralampos Gatos, Eleni Tsianaka, Konstantinos Vagkopoulos, Konstantinos Paterakis, Kostas N Fountas
Anterior cervical spine procedures have been associated with satisfactory outcomes. However, the occurrence of troublesome complications, although uncommon, needs to be taken into consideration. The purpose of our study was to assess the actual incidence of anterior cervical spine procedure-associated complications and identify any predisposing factors. A total of 114 patients undergoing anterior cervical procedures over a 6-year period were included in our retrospective, case-control study. The diagnosis was cervical radiculopathy, and/or myelopathy due to degenerative disc disease, cervical spondylosis, or traumatic cervical spine injury...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29057338/single-anterior-cervical-discectomy-and-fusion-acdf-using-self-locking-stand-alone-polyetheretherketone-peek-cage-evaluation-of-pain-and-health-related-quality-of-life
#3
Stylianos Kapetanakis, Tryfon Thomaidis, George Charitoudis, Pavlos Pavlidis, Panagiotis Theodosiadis, Grigorios Gkasdaris
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) constitutes the conventional treatment of cervical disc herniation due to degenerative disc disease (DDD). ACDF with plating presents a variety of complications postoperatively and stand-alone cages are thought to be a promising alternative. The aim of this study was firstly, to analyze prospectively collected data from a sample of patients treated with single ACDF using C-Plus self-locking stand-alone PEEK cage system, without the use of plates or screws, in order to evaluate pain levels of patients, utilizing Neck and Arm Pain scale as an expression of visual analogue scale (VAS)...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29053719/total-disc-replacement-using-tissue-engineered-intervertebral-discs-in-the-canine-cervical-spine
#4
Yu Moriguchi, Jorge Mojica-Santiago, Peter Grunert, Brenton Pennicooke, Connor Berlin, Thamina Khair, Rodrigo Navarro-Ramirez, Rodolfo J Ricart Arbona, Joseph Nguyen, Roger Härtl, Lawrence J Bonassar
The most common reason that adults in the United States see their physician is lower back or neck pain secondary to degenerative disc disease. To date, approaches to treat degenerative disc disease are confined to purely mechanical devices designed to either eliminate or enable flexibility of the diseased motion segment. Tissue engineered intervertebral discs (TE-IVDs) have been proposed as an alternative approach and have shown promise in replacing native IVD in the rodent tail spine. Here we demonstrate the efficacy of our TE-IVDs in the canine cervical spine...
2017: PloS One
https://www.readbyqxmd.com/read/29019878/a-comparison-of-anterior-cervical-discectomy-and-fusion-combined-with-cervical-disc-arthroplasty-and-cervical-disc-arthroplasty-for-the-treatment-of-skip-level-cervical-degenerative-disc-disease-a-retrospective-study
#5
COMPARATIVE STUDY
Ting-Kui Wu, Bei-Yu Wang, Ming-Dan Deng, Ying Hong, Xin Rong, Hua Chen, Yang Meng, Hao Liu
Anterior cervical discectomy and fusion (ACDF) has been widely performed for the treatment of multilevel cervical degenerative disc disease (CDDD). In recent decades, cervical disc arthroplasty (CDA) and hybrid surgery (HS) have been developed to overcome the shortcomings of ACDF. Controversy still remains with regard to the optimal surgical procedure for skip-level CDDD.A total of 55 patients who received surgical treatment for skip-level CDDD in our department were reviewed. The patients were divided into the HS group (n = 29) and the CDA group (n = 26)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29019591/x-ray-dynamic-observation-of-cervical-degenerative-disease-induced-by-unbalanced-dynamic-and-static-forces-in-rats-1
#6
Hua Xie, Yongjing Huang, Luming Nong, Nanwei Xu, Gongming Gao, Dong Zhou
PURPOSE: To investigate dynamically the X-ray appearance of cervical degenerative disease induced by unbalanced dynamic and static forces in rats. METHODS: A total of 60 Sprague Dawley rats were randomized into test (n=45) and control (n=15) groups, which were randomly subdivided into the one-, three- and six-month post-operative groups. The test group included 10, 15 and 20 rats at the respective corresponding post-operative stage and the control group included five rats at each time-point...
September 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29017298/space-available-for-the-cervical-spinal-cord-of-asymptomatic-adult-nigerians
#7
Chika Anele Ndubuisi, Wilfred C Mezue, Samuel C Ohaegbulam
OBJECTIVE: The space available for the spinal cord (SAC) is a measure of spinal cord functional reserve and may vary in different societies. The objective of this study is to measure normal SAC at each subaxial cervical disc level of asymptomatic adult Nigerians and to compare obtained values with published studies worldwide. METHODS: This is a prospective, cross-sectional study using magnetic resonance imaging facility at Memfys Hospital Enugu, from 2012 to 2013...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/28986691/spinal-motion-preservation-surgery-indications-and-applications
#8
REVIEW
Ioannis D Gelalis, Dimitrios V Papadopoulos, Dionysios K Giannoulis, Andreas G Tsantes, Anastasios V Korompilias
Fusion is one of the most commonly performed spinal procedures, indicated for a wide range of spinal problems. Elimination of motion though results in accelerated degeneration of the adjacent level, known as adjacent level disease. Motion preservation surgical methods were developed in order to overcome this complication. These methods include total disc replacement, laminoplasty, interspinous implants and dynamic posterior stabilization systems. The initial enthusiasm about these methods was followed by certain concerns about their clinical usefulness and their results...
October 6, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28929036/factors-affecting-length-of-stay-following-elective-anterior-and-posterior-cervical-spine-surgery
#9
Frank J Yuk, Akbar Y Maniya, Jonathan J Rasouli, Alexa M Dessy, Patrick J McCormick, Tanvir F Choudhri
Background Disease of the cervical spine is widely prevalent, most commonly secondary to degenerative disc changes and spondylosis. Objective The goal of the paper was to identify a possible discrepancy regarding the length of stay (LOS) between the anterior and posterior approaches to elective cervical spine surgery and identify contributing factors. Methods A retrospective study was performed on 587 patients (341 anterior, 246 posterior) that underwent elective cervical spinal surgery between October 2001 and March 2014...
July 10, 2017: Curēus
https://www.readbyqxmd.com/read/28894375/impact-of-t1-slope-on-surgical-and-adjacent-segment-degeneration-after-bryan-cervical-disc-arthroplasty
#10
Peng Yang, Yongqian Li, Jia Li, Yong Shen
BACKGROUND: This retrospective study investigated an association between preoperative T1 slope and surgical and adjacent segment degeneration (SASD) after Bryan cervical disc arthroplasty (BCDA) in patients with cervical degenerative disc disease. METHODS: Based on preoperative standing lateral radiographs, 90 patients were classified according to T1 slope that was higher or lower than the 50th percentile (high T1 or low T1, 28 and 62 patients, respectively). Patients were also classified as SASD or non-SASD (38 and 52 patients, respectively) determined by radiographs at final follow-up...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28888674/geographical-variations-in-clinical-presentation-and-outcomes-of-decompressive-surgery-in-patients-with-symptomatic-degenerative-cervical-myelopathy-analysis-of-a-prospective-international-multicenter-cohort-study-of-757-patients
#11
Michael G Fehlings, Branko Kopjar, Ahmed Ibrahim, Lindsay A Tetreault, Paul M Arnold, Helton Defino, Shashank Sharad Kale, S Tim Yoon, Giuseppe M Barbagallo, Ronald H M Bartels, Qiang Zhou, Alexander R Vaccaro, Mehmet Zileli, Gamaliel Tan, Yasutsugu Yukawa, Darrel S Brodke, Christopher I Shaffrey, Osmar Santos de Moraes, Eric J Woodard, Massimo Scerrati, Masato Tanaka, Tomoaki Toyone, Rick C Sasso, Michael E Janssen, Ziya L Gokaslan, Manuel Alvarado, Ciaran Bolger, Christopher M Bono, Mark B Dekutoski
BACKGROUND CONTEXT: Degenerative cervical myelopathy (DCM) is a progressive degenerative spine disease and the most common cause of spinal cord impairment in adults worldwide. There is a paucity of studies reporting on regional variations in demographics, clinical presentation, disease causation and surgical effectiveness. PURPOSE: To evaluate differences in demographics, causative pathology, management strategies, surgical outcomes, length of hospital stay and complications across four geographic regions...
September 6, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28887690/cervical-sagittal-alignment-after-different-anterior-discectomy-procedures-for-single-level-cervical-degenerative-disc-disease-randomized-controlled-trial
#12
Roland D Donk, Hisse Arnts, Wim I M Verhagen, Hans Groenewoud, Andre Verbeek, Ronald H M A Bartels
BACKGROUND: The effect of anterior cervical discectomy without fusion (ACD), ACD with fusion by stand-alone cage (ACDF) or with arthroplasty (ACDA) on cervical sagittal alignment is not known and is the subject of this study. METHODS: A total of 142 adult patients with single-level cervical disease were at random allocated to different procedures: ACD (45), ACDF (47) and ACDA (50). Upright cervical spine radiographs were obtained. Angles of the involved angle and the angle between C2 and C7 were determined...
September 8, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28881110/endoscopic-spine-surgery
#13
REVIEW
Gun Choi, Chetan S Pophale, Bhupesh Patel, Priyank Uniyal
Surgical treatment of the degenerative disc disease has evolved from traditional open spine surgery to minimally invasive spine surgery including endoscopic spine surgery. Constant improvement in the imaging modality especially with introduction of the magnetic resonance imaging, it is possible to identify culprit degenerated disc segment and again with the discography it is possible to diagnose the pain generator and pathological degenerated disc very precisely and its treatment with minimally invasive approach...
September 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28816821/adjacent-segment-disease-after-cervical-spine-fusion-evaluation-of-a-70-patient-long-term-follow-up
#14
Mohamed Alhashash, Mootaz Shousha, Heinrich Boehm
STUDY DESIGN: A retrospective study of 70 patients undergoing surgical treatment for adjacent segment disease (ASD) after anterior cervical decompression and fusion (ACDF). OBJECTIVES: To analyze the risk factors for the development of ASD in patients who underwent ACDF. SUMMARY OF BACKGROUND DATA: ACDF has provided a high rate of clinical success for the cervical degenerative disc disease; nevertheless, adjacent segment degeneration has been reported as a complication at the adjacent level secondary to the rigid fixation...
August 14, 2017: Spine
https://www.readbyqxmd.com/read/28815162/clinical-application-of-ceramics-in-anterior-cervical-discectomy-and-fusion-a-review-and-update
#15
REVIEW
Shayan Abdollah Zadegan, Aidin Abedi, Seyed Behnam Jazayeri, Hirbod Nasiri Bonaki, Alexander R Vaccaro, Vafa Rahimi-Movaghar
STUDY DESIGN: Narrative review. OBJECTIVES: Anterior cervical discectomy and fusion (ACDF) is a reliable procedure, commonly used for cervical degenerative disc disease. For interbody fusions, autograft was the gold standard for decades; however, limited availability and donor site morbidities have led to a constant search for new materials. Clinically, it has been shown that calcium phosphate ceramics, including hydroxyapatite (HA) and tricalcium phosphate (TCP), are effective as osteoconductive materials and bone grafts...
June 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28803345/substantial-clinical-benefit-for-neck-disability-index-revisited-establishing-the-goal-for-treatment
#16
Roland D Donk, Andre L M Verbeek, Wim I M Verhagen, Hans Groenewoud, Allard T F Hosman, Ronald H M A Bartels
PURPOSE: It is difficult for clinicians to inform patients about the success rate of a treatment as a cervical anterior discectomy procedure. Ideally, a proportion of good outcome as rated by patients is known. Patient-reported outcome measurements are helpful. The purpose is to relate the difference in Neck Disability Index (NDI) after a cervical anterior discectomy procedure for single level cervical degenerative disc disease with the patients' rating of their actual clinical situation after long-term follow-up to define the substantial clinical benefit (SCB)...
August 12, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28797605/space-available-for-cord-motion-and-disc-degeneration-at-the-adjacent-segments-level-of-degenerative-cervical-spondylolisthesis-using-kinematic-mri
#17
Permsak Paholpak, Alexander Nazareth, Kaku Barkoh, Larry V Lee, Joshua Lucas, Zorica Buser, Jeffrey C Wang
The objective was to evaluate motion, disc degeneration and Space Available for Cord (SAC) at the adjacent segments of degenerative cervical spondylolisthesis (DCS) using kinematic Magnetic Resonance Imaging (kMRI). The cervical spine kMRI of sixty-one DCS spinal levels (38 anterolisthesis and 23 retrolisthesis) were analyzed at the listhesis level and its adjacent segments in three position using kMRI. MRAnalyzer3 was used to analyze translation, angular motion and SAC. The caudad level had significantly less translation motion than the listhesis level in overall DCS or grade 2 anterolisthesis group (P<0...
November 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28718697/pain-drawings-predict-outcome-of-surgical-treatment-for-degenerative-disc-disease-in-the-cervical-spine
#18
Anna MacDowall, Yohan Robinson, Martin Skeppholm, Claes Olerud
INTRODUCTION: Pain drawings have been frequently used in the preoperative evaluation of spine patients. For lumbar conditions comprehensive research has established both the reliability and predictive value, but for the cervical spine most of this knowledge is lacking. The aims of this study were to validate pain drawings for the cervical spine, and to investigate the predictive value for treatment outcome of four different evaluation methods. METHODS: We carried out a post hoc analysis of a randomized controlled trial, comparing cervical disc replacement to fusion for radiculopathy related to degenerative disc disease...
August 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28704907/effect-of-modic-changes-in-cervical-degenerative-disease
#19
Kyung Tag Kang, Dong Wuk Son, Oik Kwon, Su Hun Lee, Jong Uk Hwang, Dong Ha Kim, Jun Seok Lee, Geun Sung Song
OBJECTIVE: Modic changes are signal intensity changes in adjacent vertebral bone marrow on magnetic resonance imaging. Few studies have investigated these changes with regard to the cervical spine. In this study, we investigated the associations between cervical degenerative disease and Modic changes. METHODS: We conducted a retrospective collection of radiological data in patients with neck pain at Pusan National University Yangsan Hospital from January 2010 to December 2014...
June 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/28662992/candidate-gene-investigation-of-spinal-degenerative-osteoarthritis-in-greek-population
#20
E Liva, I Panagiotou, S Palikyras, E Parpa, E Tsilika, P Paschou, K Mystakidou
BACKGROUND CONTEXT: Few data exist concerning the natural history of degenerative osteoarthritis of the spine and its associated gene investigation. Degenerative osteoarthritis of the spine demonstrates an international prevalence of 15% in the general population and over 50% in people aged over 60 years. PURPOSE: The aim of this Greek case-control study is to examine gene polymorphisms that have been previously shown or hypothesized to be correlated to degenerative osteoarthritis of the spine...
June 26, 2017: Spine Journal: Official Journal of the North American Spine Society
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