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cervical degenerative disc disease

Zhongjun Mo, Qi Li, Zhiwei Jia, Jiemeng Yang, Duo Wai-Chi Wong, Yubo Fan
No abstract text is available yet for this article.
October 12, 2016: European Spine Journal
Hang Feng, Xiangyi Fang, Dageng Huang, Chengcheng Yu, Songchuan Zhao, Dingjun Hao
BACKGROUND CONTEXT: Cervical disc arthroplasty has been gradually adopted as an alternative for the treatment of cervical degenerative disease. However, there is a large discrepancy between footprints of currently available cervical disc prostheses and anatomic dimensions of cervical end plates. PURPOSE: This study aimed to accurately and comprehensively quantify the three-dimensional (3D) anatomic morphology of the cervical vertebral end plate and provide a theoretical basis for designing appropriate disc prostheses...
October 3, 2016: Spine Journal: Official Journal of the North American Spine Society
Jason Man-Kit Ho, Hing-Yuen Law, Shing-Chau Yuen, Kwong-Yui Yam
The authors present 2 cases of cervical myelopathy produced by engorged vertebral veins due to overshunting. Overshunting-associated myelopathy is a rare complication of CSF shunting. Coexisting cervical degenerative disc disease may further increase the difficulty of diagnosing the condition. Neurosurgeons and others who routinely evaluate patients with intracranial shunts should be familiar with this rare but possible diagnosis.
September 2016: Neurosurgical Focus
Richard Bostelmann, Tamara Bostelmann, Adrian Nasaca, Hans Jakob Steiger, Frank Zaucke, Christoph Schleich
BACKGROUND CONTEXT: On a molecular level, maturation or degeneration of human intervertebral disc is among others expressed by the content of glycosaminoglycans (GAGs). According to the degenerative status, the disc content can differ in nucleus pulposus (NP) and annulus fibrosus (AF), respectively. Research in this area was conducted mostly on postmortem samples. Although several radiological classification systems exist, none includes biochemical features. Therefore, we focused our in vivo study on a widely spread and less expensive imaging technique for the cervical spine and the correlation of radiological patterns to biochemical equivalents in the intervertebral discs...
August 25, 2016: Spine Journal: Official Journal of the North American Spine Society
Zhonghai Li, Yantao Zhao, Jiaguang Tang, Dongfeng Ren, Jidong Guo, Huadong Wang, Li Li, Shuxun Hou
PURPOSE: To compare perioperative parameters, clinical outcomes, radiographic parameters, and complication rates of the new zero-profile, stand-alone Fidji cervical cage with those of the stand-alone cages with a titanium plate for anterior cervical discectomy and fusion (ACDF) for the surgical treatment of single- and multilevel cervical degenerative disc disease (DDD). METHODS: Between October 2009 and December 2013, 152 consecutive patients [86 males and 52 females; mean age 51...
August 23, 2016: European Spine Journal
Roland Donk, Andre Verbeek, Wim Verhagen, Hans Groenewoud, Allard Hosman, Ronald Bartels
OBJECTIVE: The Neck Disability Index (NDI) is a patient self-assessed outcome measurement tool to assess disability, and that is frequently used to evaluate the effects of the treatment of neck-related problems. In individualized medicine it is mandatory that patients can interpret data in order to choose a treatment. A change of NDI or an absolute NDI is generally meaningless to a patient. Therefore, a correlation between the qualification of the clinical situation rated by the patient and the NDI score was evaluated...
2016: PloS One
Lin Xie, Ming Liu, Fan Ding, Peng Li, Dezhang Ma
PURPOSE: This meta-analysis of randomized controlled trials (RCTs) aims to evaluate the efficacy and safety in cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) for treating cervical degenerative disc diseases (CDDDs). METHODS: The authors searched RCTs in the electronic databases (Cochrane Central Register of Controlled Trials, PubMed, EMBASE, Medline, Embase, Springer Link, Web of Knowledge, OVID and Google Scholar) from their establishment to march 2016 without language restrictions...
2016: SpringerPlus
Sun Qizhi, Li Peijia, Sun Lei, Chen Junsheng, Li Jianmin
BACKGROUND: Noncontiguous cervical spondylotic myelopathy (CSM) is a special degenerative disease because of the intermediate normal level or levels between supra and infraabnormal levels. Some controversy exists over the optimal procedure for two noncontiguous levels of CSM. The study was to evaluate the outcomes of the anterior cervical discectomy and fusion (ACDF) with zero-profile devices for two noncontiguous levels of CSM. MATERIALS AND METHODS: 17 consecutive patients with two noncontiguous levels of CSM operated between December 2009 and August 2012 were included in the study...
July 2016: Indian Journal of Orthopaedics
Huang-Chou Chang, Tsung-Hsi Tu, Hsuan-Kan Chang, Jau-Ching Wu, Li-Yu Fay, Peng-Yuan Chang, Ching-Lan Wu, Wen-Cheng Huang, Henrich Cheng
INTRODUCTION: Combination of ACDF and ACCF (Anterior cervical discectomy or corpectomy with fusion) has been demonstrated to be effective for multi-level CSM (cervical spondylotic myelopathy). However, the combination of ACCF and cervical disc arthroplasty (CDA) for three-level CSM has never been addressed. METHODS: Consecutive patients (>18 years old) with CSM caused by segmental ossification of posterior longitudinal ligament (OPLL) and degenerative disc disease (DDD) were reviewed...
July 26, 2016: World Neurosurgery
Yuchen Duan, Yunbei Yang, Yayi Wang, Hao Liu, Ying Hong, Quan Gong, Yueming Song
Zero-profile device was applied to diminish the irritation of the esophagus in the treatment of cervical degenerative disc disease. However, the clinical application of the zero-profile device has not been testified with clinical evidence. The aim of the meta-analysis was to systematically compare the safety and effectiveness of anterior cervical discectomy and fusion with zero-profile device with plate and cage for the treatment of cervical degenerative disc disease. Electronic searches of PubMed and Embase were conducted up to May 2015...
November 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
B Oyinkan Marquis, Patrick M Capone
Myelopathy is an inclusive term, referring to pathology leading to a neurologic deficit related to the spinal cord. The clinical diagnosis of myelopathy requires a detailed history and physical examination to define the clinical syndrome. Neuroimaging is indicated in most instances of new-onset myelopathy. It is indicated also when the worsening of a myelopathy is unexplained. Advances in neuroimaging have proved to play a vital role in diagnosis. Appropriate diagnosis and treatment are dependent upon an adequate imaging evaluation to establish the presence of mechanical stability, extrinsic spinal cord compression, or an intramedullary lesion...
2016: Handbook of Clinical Neurology
Benedikt W Burkhardt, Moritz Brielmeier, Karsten Schwerdtfeger, Joachim M K Oertel
INTRODUCTION: The purpose was to evaluate the long-term clinical outcome for the surgical treatment of cervical disc herniation. Special focus was given to assess pain, functional outcome, and symptomatic adjacent segment disease (ASD) after anterior cervical discectomy and fusion (ACDF) and ACDF with Caspar plating (ACDF+PS). METHODS: Hospital records of 226 patients who were affected by soft cervical disc herniation and treated by ACDF or ACDF+PS were reviewed...
August 2016: Neurosurgery
Bjarne Lied, Oystein Helseth, Kare Ekseth, Ben Heskestad, Eirik Helseth
INTRODUCTION: There is an increasing demand for surgery of degenerative spinal disease. Limited health care resources draw attention to the need for cost-effective treatments. Outpatient surgery, when safe and feasible, is more cost-effective than inpatient surgery. The aim of this study is to study types and rates of complications following surgery for herniated cervical disc and fusion. METHODS: Complications were recorded prospectively in 759 outpatients undergoing outpatient cervical surgery at the private Oslofjord Clinic in the time period 2008 to 2015...
August 2016: Neurosurgery
Robert Jackson, Darin Eric Johnson
INTRODUCTION: Studies suggest significant biomechanical and clinical differences exist between total disk replacement (TDR) and anterior cervical discectomy and fusion (ACDF) patients treated at multiple cervical levels. However, long-term results for treatment of multilevel cervical degenerative disc disease are lacking. Here we evaluate 7-year neurological and clinical outcomes of patients treated at 2 contiguous levels with TDR or ACDF. METHODS: Prospective, randomized, multicenter, controlled clinical trial...
August 2016: Neurosurgery
Mhamad Faour, Joshua T Anderson, Arnold R Haas, Rick Percy, Stephen T Woods, Uri M Ahn, Nicholas U Ahn
STUDY DESIGN: A retrospective comparative cohort study. OBJECTIVE: To compare return to work (RTW) rates for patients who underwent single-level cervical fusion for radiculopathy compared with fusion for degenerative disc disease (DDD) as an indication for surgery. SUMMARY OF BACKGROUND DATA: Studies have shown that workers' compensation subjects have less favorable surgical and functional outcomes compared with the general population. Cervical decompression and fusion have provided great results with relieving radicular symptoms...
July 15, 2016: Spine
Sheng Bin, Huang Xiangwang, Xiao Sheng, Xiang Tiecheng, Liu Xiangyang, Zhang Yi, Liu Bin
STUDY DESIGN: Retrospective study. OBJECTIVE: To evaluate the outcome of artificial cervical disc replacement (ACDR) for the treatment of adjacent segment disease (ASD) after anterior cervical decompression and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF is the useful procedure for degenerative cervical diseases. However, studies have reported accelerated degeneration of functional spinal units (FSUs) adjacent to the fusion site after ACDF...
June 28, 2016: Clinical Spine Surgery
Majid Reza Farrokhi, Zahra Nikoo, Mehrnaz Gholami, Khadijeh Hosseini
STUDY DESIGN: Prospective, single-blind randomized controlled clinical study. OBJECTIVE: To compare polyetheretherketone (PEEK) cage with a novel Acrylic cage to find out which fusion cage yielded better clinical outcomes following single-level anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF is considered a standard neurosurgical treatment for degenerative diseases of cervical intervertebral discs. There are many options, including bone grafts, bone cement, and spacers made of titanium, carbon fiber, and synthetic materials, used to restore physiologic disc height and enhance spinal fusion, but the ideal device, which would provide immediate structural support and subsequent osteo-integration and stability, has not been identified yet...
June 28, 2016: Clinical Spine Surgery
Joseph D Smucker, Scott R Bassuener, Rick C Sasso, K Daniel Riew
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: This study investigates the incidence of long-term dysphagia in cervical disc arthroplasty, and anterior cervical discectomy and fusion (ACDF) patients. SUMMARY OF BACKGROUND DATA: No long-term comparison of dysphagia between cervical arthroplasty and fusion patients has been published. Widely variable short-term postsurgical dysphagia rates have been reported. MATERIALS AND METHODS: Cohorts for this study are patients with single-level cervical degenerative disc disease previously enrolled in a randomized clinical trial comparing cervical arthroplasty and ACDF...
June 27, 2016: Clinical Spine Surgery
Matthew F Gornet, Vaneet Singh, Francine W Schranck, Anastasia K Skipor, Joshua J Jacobs
STUDY DESIGN: Prospective longitudinal study. OBJECTIVE: The serum titanium (Ti) concentrations were examined in patients implanted with a PRESTIGE LP™ Cervical Disc System (Medtronic, Inc., Memphis, TN). The metal-on-metal disc with ball-in-trough articulation is made of titanium alloy/titanium carbide composite (Ti-6Al-4 V/TiC). SUMMARY OF BACKGROUND DATA: Cervical disc arthroplasty (CDA) provides a motion-preserving treatment alternative to anterior cervical discectomy and fusion for degenerative cervical disc disease...
June 17, 2016: Spine
Shihua Zou, Junyi Gao, Bin Xu, Xiangdong Lu, Yongbin Han, Hui Meng
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) has been considered as a gold standard for symptomatic cervical disc degeneration (CDD), which may result in progressive degeneration of the adjacent segments. The artificial cervical disc was designed to reduce the number of lesions in the adjacent segments. Clinical studies have demonstrated equivalence of cervical disc arthroplasty (CDA) for anterior cervical discectomy and fusion in single segment cervical disc degeneration...
June 17, 2016: European Spine Journal
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