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https://www.readbyqxmd.com/read/29781435/cochrane-postpones-comprehensive-free-access-to-reviews
#1
Talha Burki
No abstract text is available yet for this article.
May 12, 2018: Lancet
https://www.readbyqxmd.com/read/29778700/paediatric-cystolitholapaxy-through-the-mitrofanoff-monti-channel
#2
J S Thomas, N Smeulders, F Yankovic, S Undre, I Mushtaq, P-J López, P Cuckow
INTRODUCTION: Bladder calculi are a known complication of bladder augmentation. Open cystolithotomy remains the preferred option for treating large or multiple stones. Increasingly, however, minimal access techniques have been used. Reports of Mitrofanoff cystolitholapaxy are rare and have been limited to adults. This study presented a two centre series of children treated by cystolitholapaxy via the Mitrofanoff/Monti channel. MATERIALS AND METHODS: With institutional approval the current study retrospectively reviewed and identified 14 patients, on a prospective database, who underwent Mitrofanoff cystolitholapaxy to treat bladder calculi at two independent institutions in the UK and Chile between 2004 and 2016...
April 4, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29772989/a-systematic-review-of-all-smart-phone-applications-specifically-aimed-for-use-as-a-scoliosis-screening-tool
#3
Qais Naziri, Jadie Detolla, Westley Hayes, Steven Burekhovich, Andrew Merola, Chibukem Akamnanu, Carl B Paulino
The scoliometer is an inclinometer commonly used in scoliosis screening. The device is used during an Adam's forward bend test, in which a patient bends forward at the hips to measure deformity of the rib cage and spinal column. If a sufficient angle of rotation is measured, then the appropriate referrals and x-rays can be made and taken. This ubiquitous screening tool allows for a quick and simple scoliosis screening and is a mainstay of scoliosis management. With the advent and rapid improvement of smart phone technology, many scoliometer applications have become readily accessible...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29752769/systematic-review-on-ureteral-access-sheaths-facts-and-myths
#4
REVIEW
Vincent De Coninck, Etienne Xavier Keller, María Rodríguez-Monsalve, Marie Audouin, Steeve Doizi, Olivier Traxer
OBJECTIVES: To review literature on all available ureteral access sheaths (UASs) with their indications, limitations, risks, advantages and disadvantages in current modern endourological practice. PATIENTS AND METHODS: Two authors searched Medline, Scopus, Embase and Web of Science databases to identify studies on UASs published in English. No time period restriction was applied. All original articles reporting about outcomes or innovations were included. Additional articles identified through references lists were also included...
May 11, 2018: BJU International
https://www.readbyqxmd.com/read/29743722/management-of-patients-with-acute-promyelocytic-leukemia
#5
REVIEW
Sabine Kayser, Richard F Schlenk, Uwe Platzbecker
With the introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) acute promyelocytic leukemia (APL) has become from a detrimental to one of the most curable malignant diseases in humans. In particular, the chemotherapy-free regimen with ATO/ATRA has been proven to be highly effective in de novo APL and has become standard first-line therapy in younger adult, non-high-risk patients. Nevertheless, early death is still a major issue in APL, particularly in older patients, emphasizing the need of rapid diagnostics and supportive care together with immediate access to ATRA-based therapy...
April 24, 2018: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/29736848/the-most-downloaded-and-most-cited-articles-in-radiology-journals-a-comparative-bibliometric-analysis
#6
Sora Baek, Dae Young Yoon, Kyoung Ja Lim, Young Kwon Cho, Young Lan Seo, Eun Joo Yun
OBJECTIVES: To evaluate and compare the characteristics of the most downloaded and most cited articles in radiology journals. METHODS: We selected 41 radiology journals that provided lists of both the most downloaded and most cited articles on their websites, and identified the 596 most downloaded articles and 596 most cited articles. We compared the following characteristics of the most downloaded and most cited articles: year of publication, journal title, department of the first author, country of origin, publication type, radiologic subspecialty, radiologic technique and accessibility...
May 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29733352/adaptation-of-a-hospital-electronic-referral-system-for-antimicrobial-stewardship-prospective-audit-and-feedback-rounds
#7
Matthew D M Rawlins, Edward Raby, Frank M Sanfilippo, Rae Douglass, Jonathan Chambers, Duncan McLellan, John R Dyer
Objective: To evaluate the impact of the adaptation of an existing electronic referral application for use in antimicrobial stewardship prospective audit and feedback rounds (antimicrobial rounds). Design: Retrospective, single-centre observational study between March 2015 and February 2016. Setting: A new quaternary referral centre. Study Participants: Adults referred for antimicrobial rounds outside of the intensive care and haematology units...
May 4, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29732935/use-of-autologous-fat-grafts-for-the-endoscopic-reconstruction-of-skull-base-defects-indications-outcomes-and-complications
#8
Kent Lam, Amber U Luong, William C Yao, Martin J Citardi
Background The use of abdominal free fat is a traditional surgical method for the repair and reconstruction of the anterior skull base. Our objective is to assess the outcomes associated with the autologous fat graft to endoscopically repair anterior skull base defects at a single tertiary care center. Methods All patients, who underwent endoscopic skull base repair utilizing abdominal free fat from September 2009 to June 2016, were included for retrospective chart review. Evaluated outcome measurements included (1) the successful closure of preoperative and intraoperative cerebrospinal fluid (CSF) leaks and (2) complications at both donor and recipient graft sites during the postoperative periods...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29732915/retrograde-ureteroscopic-management-of-large-renal-calculi-a-single-institutional-experience-and-concise-literature-review
#9
Kymora Scotland, Benjamin Rudnick, Kelly A Healy, Scott G Hubosky, Demetrius Bagley
INTRODUCTION: Advances in flexible ureteroscope design and accessory instrumentation have allowed for more challenging cases to be treated ureteroscopically. Here we evaluate our experience with ureteroscopy for the management of large renal calculi (≥ 2cm) and provide a concise review of recent reports.. METHODS: A retrospective review was undertaken of all ureteroscopy cases between 2004 and 2014 performed by the endourologic team at a single academic tertiary care institution...
May 5, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29726792/early-surgical-management-and-long-term-surgical-outcome-for-intraventricular-hemorrhage-related-posthemorrhagic-hydrocephalus-in-shunt-treated-premature-infants
#10
Hans Christoph Bock, Jacqueline Feldmann, Hans Christoph Ludwig
OBJECTIVE Perinatal intraventricular hemorrhage (IVH) in premature neonates may lead to severe neurological disability and lifelong treatment requirement for consecutive posthemorrhagic hydrocephalus (PHHC). Early CSF diversion as a temporizing measure, or a permanent ventriculoperitoneal shunt (VPS), is the treatment of choice. Preterm neonates are not only at high risk for different perinatal but also for treatment-related complications. The authors reviewed their institutional neurosurgical management for preterm neonates with IVH-related PHHC and evaluated shunt-related surgical outcome for this particular hydrocephalus etiology after completion of a defined follow-up period of 5 years after initial shunt insertion...
May 4, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29717677/facilitating-earlier-diagnosis-of-cardiovascular-disease-through-point-of-care-biosensors-a-review
#11
Mackenzie M Honikel, Chi-En Lin, David Probst, Jeffrey T La Belle
Cardiovascular disease (CVD) accounts for 30% of all global deaths and is predicted to dominate in the coming years, despite vast improvements in medical technology. Current clinical methods of assessing an individual's cardiovascular health include blood tests to monitor relevant biomarker levels as well as varying imaging modalities such as electrocardiograms, computed tomography, and angiograms to assess vasculature. As informative as these tools are, they each require lengthy scheduling, preparation, and highly trained personnel to interpret the results before any information is accessible to patients, often leading to delayed treatment, which can be fatal...
2018: Critical Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/29705476/pain-related-encephalic-regions-influenced-by-yoga-meditation-an-integrative-review
#12
REVIEW
Petra Jurisic, Daiana Cristina Salm, Cintia Vieira, Francisco José Cidral-Filho, Leidiane Mazzardo-Martins, Daniel Fernandes Martins
INTRODUCTION: The mechanisms underlying the use of yoga in pain relief are still unclear. This study reviewed literature reports on encephalic activity related to analgesia induced by yoga meditation practice. METHODS: This integrative review examined studies published in the Pubmed, LILACS and MEDLINE databases without restriction of the year of publication. The research involved 16 descriptors related to the words: yoga, pain and neuroimaging methods. Inclusion criteria involved only the publications available online, with free access and written in English...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29702700/what-capacity-exists-to-provide-essential-inpatient-care-to-small-and-sick-newborns-in-a-high-mortality-urban-setting-a-cross-sectional-study-in-nairobi-city-county-kenya
#13
Georgina A V Murphy, David Gathara, Nancy Abuya, Jacintah Mwachiro, Sam Ochola, Robert Ayisi, Mike English
INTRODUCTION: Appropriate demand for, and supply of, high quality essential neonatal care is key to improving newborn survival but evaluating such provision has received limited attention in low- and middle-income countries. Moreover, specific local data are needed to support healthcare planning for this vulnerable population. METHODS: We conducted health facility assessments between July 2015-April 2016, with retrospective review of admission events between 1st July 2014 and 30th June 2015, and used estimates of population-based incidence of neonatal conditions in Nairobi to explore access and evaluate readiness of public, private not-for-profit (mission), and private-for-profit (private) sector facilities providing 24/7 inpatient neonatal care in Nairobi City County...
2018: PloS One
https://www.readbyqxmd.com/read/29693363/edaravone-in-the-treatment-of-amyotrophic-lateral-sclerosis-efficacy-and-access-to-therapy-a-roundtable-discussion
#14
Benjamin Rix Brooks, James A Jorgenson, Barbara J Newhouse, Jeremy M Shefner, Wendy Agnese
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neuromuscular disease affecting approximately 5 out of every 100,000 individuals living in the United States. ALS is associated with 50% mortality within 30 months of initial symptom onset. The rarity of the disease, along with the significant inter- and intra-patient variability in clinical course and a lack of reliable biomarkers, have rendered the development of effective agents to treat ALS a challenge. Because oxidative stress is considered a contributing factor to ALS onset and progression, drugs that eliminate free radicals may protect motor neurons from damage potentially caused by free-radical and oxidative stress...
April 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/29689380/mpa-a-free-accessible-and-efficient-pipeline-for-single-nucleotide-variant-annotation-and-prioritization-for-next-generation-sequencing-routine-molecular-diagnosis
#15
Kevin Yauy, David Baux, Henri Pegeot, Charles Van Goethem, Charly Mathieu, Thomas Guignard, Raul Juntas Morales, Delphine Lacourt, Martin Krahn, Vilma-Lotta Lehtokari, Gisele Bonne, Sylvie Tuffery-Giraud, Michel Koenig, Mireille Cossée
Interpretation of next-generation sequencing data constitutes the main limitation in molecular genetics diagnosis. In diagnosis of myopathies and muscular dystrophies (MMD), another major issue is to efficiently predict pathogenicity of variants identified in large genes, especially TTN, since current in silico prediction tools show limitations to predict and rank the numerous variants of such genes. We propose a unique variant prioritization score called mobidic prioritization algorithm (MPA) based on curated interpretation for previously reported variants, biological assumptions, and splice and missense predictors to prioritize all types of single nucleotide variants...
April 21, 2018: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/29677133/modified-fusarium-mycotoxins-in-cereals-and-their-products-metabolism-occurrence-and-toxicity-an-updated-review
#16
REVIEW
Marcin Bryła, Agnieszka Waśkiewicz, Edyta Ksieniewicz-Woźniak, Krystyna Szymczyk, Renata Jędrzejczak
Mycotoxins are secondary fungal metabolites, toxic to humans, animals and plants. Under the influence of various factors, mycotoxins may undergo modifications of their chemical structure. One of the methods of mycotoxin modification is a transformation occurring in plant cells or under the influence of fungal enzymes. This paper reviews the current knowledge on the natural occurrence of the most important trichothecenes and zearalenone in cereals/cereal products, their metabolism, and the potential toxicity of the metabolites...
April 20, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29657068/safety-and-efficacy-of-day-case-percutaneous-nephrolithotomy-a-systematic-review-from-european-society-of-uro-technology
#17
REVIEW
Patrick Jones, Grace Bennett, Alexios Dosis, Amelia Pietropaolo, Robert Geraghty, Omar Aboumarzouk, Andreas Skolarikos, Bhaskar K Somani
CONTEXT: Day case or ambulatory percutaneous nephrolithotomy (PCNL) has risen over the last few years with the aim of discharging patients within 24h. OBJECTIVE: We perform a systematic review of literature to evaluate the outcomes of day-case PCNL surgery. EVIDENCE ACQUISITION: A Cochrane style search was performed and the following bibliographic databases were accessed: PubMed, Science Direct, Scopus, and Web of Science. This was carried out in accordance with the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) guidelines...
April 12, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29644440/a-liquid-biopsy-in-primary-lung-cancer
#18
REVIEW
Kazue Yoneda, Naoko Imanishi, Yoshinobu Ichiki, Fumihiro Tanaka
A tissue biopsy is the "golden standard" for molecular profiling that is essential in decision-making regarding treatment for malignant tumors, including primary lung cancer. However, tumor biopsies are associated with several limitations, including invasiveness and difficulty in achieving access. Liquid biopsies have several potential advantages over tissue biopsies, and recent advances in molecular technologies have enabled liquid biopsies to be introduced into daily clinical practice. Cell-free blood-based liquid biopsies to detect mutations in the epidermal growth factor receptor (EGFR) gene in the plasma have been approved and may be useful in selecting patients for treatment with tyrosine kinase inhibitors of EGFR...
April 11, 2018: Surgery Today
https://www.readbyqxmd.com/read/29625505/proximal-versus-distal-recipient-vessels-in-lower-extremity-reconstruction-a-retrospective-series-and-systematic-review
#19
John T Stranix, Zachary M Borab, William J Rifkin, Adam Jacoby, Z-Hye Lee, Lavinia Anzai, Daniel J Ceradini, Vishal Thanik, Pierre B Saadeh, Jamie P Levine
BACKGROUND:  Recipient vessels proximal to the zone of injury have traditionally been preferred for lower extremity reconstruction. However, more recent data have shown mixed outcomes when performing anastomoses distal to the zone of injury. We investigated the impact of recipient vessel location on free flap outcomes. METHODS:  Retrospective review (1979-2016); 312 soft tissue free flaps for open tibia fractures met inclusion criteria. Flap characteristics and perioperative outcomes were examined...
April 6, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29619383/-foamems-engaging-paramedics-with-free-online-open-access-education
#20
Paige Mason, Alan M Batt
BACKGROUND AND AIM: Twitter® use among paramedics and other prehospital care clinicians is on the rise and is increasingly being used as a platform for continuing education and international collaboration. In 2014, the hashtag #FOAMems was registered. It is used for the sharing of emergency medical services, paramedicine, and prehospital care-related content. It is a component of the 'free open-access meducation' (FOAM) movement. The aim of this study was to characterize and evaluate the content of #FOAMems tweets since registration...
2018: Journal of Education and Health Promotion
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