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https://www.readbyqxmd.com/read/29130789/the-evaluation-of-radiologic-methods-for-access-guidance-in-percutaneous-nephrolithotomy-a-systematic-review-of-the-literature
#1
Alberto Breda, Angelo Territo, Cesare Scoffone, Christian Seitz, Thomas Knoll, Thomas Herrmann, Mariannhe Brehmer, Palle J S Osther, Evangelos Liatsikos
INTRODUCTION: Percutaneous nephrolithotomy (PNL) is the treatment of choice for larger and complex renal calculi. First step in performing PNL is to obtain access to the renal cavity using either fluoroscopy or ultrasound (US) guidance or a combination of both. Which guiding method to choose is controversial? A systematic review of the literature was performed comparing image guidance modalities for obtaining access in PNL. Evidence acquisition and synthesis: A PubMed, Scopus and Cochrane search for peer-reviewed studies was performed using the keywords "ultrasound" AND "fluoroscopy" AND "Percutaneous nephrolithotomy"...
November 12, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/29128576/evaluation-of-tumor-pseudocapsule-status-and-its-prognostic-significance-in-renal-cell-carcinoma
#2
Wei Xi, Jiajun Wang, Li Liu, Ying Xiong, Yang Qu, Zhiyuan Lin, Xiang Chen, Zewei Wang, Jiejie Xu, Jianming Guo
PURPOSE: To determine whether tumor pseudocapsule status- extent of invasion by cancer and lack of pseudocapsule- is of prognostic value in renal cell carcinoma (RCC). MATERIALS AND METHODS: We retrospectively reviewed 1577 RCC patients of different stages who underwent nephrectomy at out institution, and 1307 (82.9%) were eligible for analyses. Presented PS was classified into completely intact (Grade 0), mere involved (Grade 1) and penetrated (Grade 2) categories...
November 8, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29124391/implementing-a-digital-real-time-hydrocephalus-and-shunt-registry-to-evaluate-contemporary-pattern-of-care-and-surgical-outcome-in-pediatric-hydrocephalus
#3
Hans Christoph Bock, Maximilian Kanzler, Ulrich-Wilhelm Thomale, Hans Christoph Ludwig
OBJECTIVE: Treatment monitoring and outcome evaluation in pediatric hydrocephalus require gapless documentation regarding surgical and clinical follow-up data beginning from day 1 of treatment in order to apply high quality of care. Endoscopic procedures, shunt insertion and revision surgeries, and individual modifications of valve hardware or pressure settings during follow-up as well as established outcome measurements are highly relevant for complete illustration of the patient's hydrocephalus histories...
November 9, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29117644/respectful-care-during-childbirth-in-health-facilities-globally-a-qualitative-evidence-synthesis
#4
Elham Shakibazadeh, Masoumeh Namadian, Meghan A Bohren, Joshua P Vogel, Arash Rashidian, Vicky Nogueira Pileggi, Sofia Madeira, Sebastian Leathersich, Ӧzge Tunçalp, Olufemi T Oladapo, João Paulo Souza, Ahmet Metin Gülmezoglu
BACKGROUND: What constitutes respectful maternity care (RMC) operationally in research and program implementation is often variable. OBJECTIVES: To develop a conceptualization of RMC. SEARCH STRATEGY: Key databases including PubMed, CINAHL, EMBASE, Global Health Library; grey literature and reference lists of relevant studies. SELECTION CRITERIA: Primary qualitative studies focusing on care occurring during labour, childbirth and/or immediate postpartum in health facilities without any restrictions on locations or publication date...
November 8, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29111991/multiple-chemical-sensitivity-review-of-the-state-of-the-art-in-epidemiology-diagnosis-and-future-perspectives
#5
Sabrina Rossi, Alessio Pitidis
OBJECTIVE: Systematic bibliography analysis of about the last 17 years on multiple chemical sensitivity (MCS) was carried out in order to detect new diagnostic and epidemiological evidence. The MCS is a complex syndrome that manifests as a result of exposure to a low level of various common contaminants. The etiology, diagnosis, and treatment are still debated among researchers. METHOD: Querying PubMed, Web of Science, Scopus, Cochrane library, both using some specific MESH terms combined with MESH subheadings and through free search, even by Google...
November 3, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29092057/health-system-dynamics-analysis-of-eyecare-services-in-trinidad-and-tobago-and-progress-towards-vision-2020-goals
#6
Tasanee Braithwaite, Blaine Winford, Henry Bailey, Petra Bridgemohan, Debra Bartholomew, Deo Singh, Subash Sharma, Rishi Sharma, Juan Carlos Silva, Alastair Gray, Samuel S Ramsewak, Rupert R A Bourne
Avoidable blindness is an important global public health concern. This study aimed to assess Trinidad and Tobago's progress towards achieving the Pan American Health Organization, 'Strategic Framework for Vision 2020: The Right to Sight-Caribbean Region,' indicators through comprehensive review of the eyecare system, in order to facilitate health system priority setting. We administered structured surveys to six stakeholder groups, including eyecare providers, patients and older adult participants in the National Eye Survey of Trinidad and Tobago...
October 30, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29077126/recent-advances-in-fluoride-free-aryne-generation-from-arene-precursors
#7
REVIEW
Fahima I M Idiris, Christopher R Jones
Aryne chemistry has experienced a remarkable renaissance in recent years, with a significant increase in the synthetic applications reported for these highly valuable reactive intermediates. This resurgence of interest is in part due to the introduction of ortho-silylaryl triflates as precursors which can be activated under mild conditions using fluoride. Alternative fluoride-free strategies have received interest in the last decade, with a number of precursors to arynes and their activators reported. These approaches offer alternative modes of reactivity which prove, in some cases, to be orthogonal to those of ortho-silylaryl triflates...
November 7, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29075799/nonintegrating-human-somatic-cell-reprogramming-methods
#8
Thorsten M Schlaeger
Traditional biomedical research and preclinical studies frequently rely on animal models and repeatedly draw on a relatively small set of human cell lines, such as HeLa, HEK293, HepG2, HL60, and PANC1 cells. However, animal models often fail to reproduce important clinical phenotypes and conventional cell lines only represent a small number of cell types or diseases, have very limited ethnic/genetic diversity, and either senesce quickly or carry potentially confounding immortalizing mutations. In recent years, human pluripotent stem cells have attracted a lot of attention, in part because these cells promise more precise modeling of human diseases...
October 27, 2017: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/29053517/total-palatal-mobilization-and-multilamellar-suturing-technique-improves-outcome-for-palatal-fistula-repair
#9
Ahmed Elsherbiny, John H Grant
BACKGROUNDS: The success rate of the surgical repair of palatal fistula after palatoplasty is often unsatisfactory. This study is a review of 15 years of single surgeon's experience with the evolution of a reliable surgical technique with high success rate. METHODS: This is a retrospective chart review of consecutive cleft cases undergoing repair of palatal fistula from 2000 to 2015. The study included 37 consecutive fistula repair cases with wide elevation and mobilization of the palatal tissues and nasal and oral layer repair...
December 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29053253/surface-plasmon-resonance-material-and-interface-design-for-universal-accessibility
#10
Samuel S Hinman, Kristy S McKeating, Quan Cheng
No abstract text is available yet for this article.
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29051136/using-google-glass-in-nonsurgical-medical-settings-systematic-review
#11
Bryn Dougherty, Sherif M Badawy
BACKGROUND: Wearable technologies provide users hands-free access to computer functions and are becoming increasingly popular on both the consumer market and in various industries. The medical industry has pioneered research and implementation of head-mounted wearable devices, such as Google Glass. Most of this research has focused on surgical interventions; however, other medical fields have begun to explore the potential of this technology to support both patients and clinicians. OBJECTIVE: Our aim was to systematically evaluate the feasibility, usability, and acceptability of using Google Glass in nonsurgical medical settings and to determine the benefits, limitations, and future directions of its application...
October 19, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29046982/ureteroscopy-for-stone-disease-in-paediatric-population-is-safe-and-effective-in-medium-volume-and-high-volume-centres-evidence-from-a-systematic-review
#12
REVIEW
Shazna Rob, Patrick Jones, Amelia Pietropaolo, Stephen Griffin, Bhaskar K Somani
PURPOSE OF REVIEW: The incidence of urinary stone disease among the paediatric population is increasing. Whilst there has been a rise in the number of original studies published on ureteroscopy (URS) in children, critical review still remains under-reported. RECENT FINDINGS: A Cochrane style systematic review was performed to identify all original articles on URS (minimum of 25 cases) for stone disease in paediatric patients between Jan. 1996 and Dec. 2016. Based on the number of reported cases, centres were divided into medium (25-49 cases) and high (≥ 50 cases) volume studies...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29040656/barriers-to-the-success-of-an-electronic-pharmacovigilance-reporting-system-in-kenya-an-evaluation-three-years-post-implementation
#13
Oscar O Agoro, Sarah W Kibira, Jenny V Freeman, Hamish S F Fraser
Objective: Electronic pharmacovigilance reporting systems are being implemented in many developing countries in an effort to improve reporting rates. This study sought to establish the factors that acted as barriers to the success of an electronic pharmacovigilance reporting system in Kenya 3 years after its implementation. Materials and Methods: Factors that could act as barriers to using electronic reporting systems were identified in a review of literature and then used to develop a survey questionnaire that was administered to pharmacists working in government hospitals in 6 counties in Kenya...
October 12, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29040161/prognostic-factor-analysis-in-325-patients-with-graves-disease-treated-with-radioiodine-therapy
#14
Danrong Yang, Jianjun Xue, Wenxia Ma, Furong Liu, Yameng Fan, Jie Rong, Aimin Yang, Yan Yu
INTRODUCTION: I therapy is a choice for Graves' hyperthyroidism. Several factors that affect the success of I treatment in Graves' disease (GD) patients have been put forward. The aim of this retrospective study was to evaluate the factors influencing the success of I therapy and the occurrence of hypothyroidism after I therapy. PATIENTS AND METHODS: We reviewed 325 GD patients, who were well documented out of 779 cases, treated with I in the First Affiliated Hospital of Xi'an Jiaotong University between 2010 and 2016...
October 16, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29032949/correction-of-hyperleucinemia-in-msud-patients-on-leucine-free-dietary-therapy
#15
Anna I Scott, Kristina Cusmano-Ozog, Gregory M Enns, Tina M Cowan
PURPOSE: Maple Syrup Urine Disease (MSUD) is a rare disorder of branched-chain amino acid catabolism associated with encephalopathy from accumulation of leucine. Leucine is closely monitored during normal growth and particularly during acute illness. As most hospitals do not have access to rapid plasma amino acid quantification, the initial management is often empirical. A model describing the reduction of plasma leucine in hyperleucinemic patients on leucine-free formula would help to guide management and optimize testing frequency...
October 5, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29024739/direct-antiviral-agents-daas-a-new-age-in-the-treatment-of-hepatitis-c-virus-infection
#16
REVIEW
Ulrich Spengler
Hepatitis C virus (HCV) is a global health problem, because infection frequently leads to chronic hepatitis C eventually progressing to liver cirrhosis and liver cancer. Improved insights into the HCV replication cycle and the role of HCV non-structural proteins have recently enabled to identify drugs directly acting on specific HCV target structures. Agents from three drug classes have been developed and approved by the health authorities. Combinations of two or more drugs from different classes achieve high (>90%) HCV clearance rates and are well tolerated...
October 10, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29023106/noncoding-rna-surveillance-the-ends-justify-the-means
#17
Cedric Belair, Soyeong Sim, Sandra L Wolin
Numerous surveillance pathways sculpt eukaryotic transcriptomes by degrading unneeded, defective, and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess ncRNAs are largely degraded by exoribonucleases, a key characteristic of these RNAs is an accessible, protein-free 5' or 3' end. Most exoribonucleases function with cofactors that recognize ncRNAs with accessible 5' or 3' ends and/or increase the availability of these ends. Noncoding RNA surveillance pathways were first described in budding yeast, and there are now high-resolution structures of many components of the yeast pathways and significant mechanistic understanding as to how they function...
October 12, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/29018840/sharing-individual-patient-and-parasite-level-data-through-the-worldwide-antimalarial-resistance-network-platform-a-qualitative-case-study
#18
Elizabeth Pisani, Stella Botchway
BACKGROUND: Increasingly, biomedical researchers are encouraged or required by research funders and journals to share their data, but there's very little guidance on how to do that equitably and usefully, especially in resource-constrained settings. We performed an in-depth case study of one data sharing pioneer: the WorldWide Antimalarial Resistance Network (WWARN). METHODS: The case study included a records review, a quantitative analysis of WAARN-related publications, in-depth interviews with 47 people familiar with WWARN, and a witness seminar involving a sub-set of 11 interviewees...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/28989286/effect-of-late-hiv-diagnosis-on-hiv-related-mortality-among-adults-in-general-hospitals-of-central-zone-tigray-northern-ethiopia-a-retrospective-cohort-study
#19
Hadera Belay, Fessahaye Alemseged, Teklit Angesom, Solomon Hintsa, Mebrahtu Abay
BACKGROUND: The global incidence of HIV infection is not significantly decreasing, especially in sub-Saharan African countries, including Ethiopia. Though there is availability and accessibility of free HIV services, people are not being diagnosed early for HIV, and hence patients are still dying of HIV-related causes. This research is aimed at verifying the effect of late diagnosis of HIV on HIV-related mortality in Central Zone Tigray, Ethiopia. METHODS: A retrospective cohort study among adult (≥15 years old) HIV patients in three general hospitals of Tigray was conducted...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28984519/surgical-management-of-incidentally-discovered-diffusely-infiltrating-low-grade-glioma
#20
Michael Opoku-Darko, Stefan T Lang, James Artindale, J Gregory Cairncross, Robert J Sevick, John J P Kelly
OBJECTIVE Occasionally, diffusely infiltrating low-grade gliomas (LGGs) are identified as incidental findings in patients who have no signs or symptoms that can be ascribed to the tumors. The diagnosis of incidental, asymptomatic LGGs has become more frequent due to the vast increase in access to medical imaging technology. While management of these lesions remains controversial, early surgery has been suggested to improve outcome. The authors set out to identify and review the characteristics and surgical outcomes of patients who underwent surgical intervention for incidental LGG...
October 6, 2017: Journal of Neurosurgery
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