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https://www.readbyqxmd.com/read/29333727/the-relation-between-maximal-voluntary-force-in-m-palmaris-longus-and-the-temporal-and-spatial-summation-of-muscle-fiber-recruitment-in-human-subjects
#1
Cécyl G Claudel, Waqas Ahmed, Vibeke S Elbrønd, Adrian P Harrison, Else Marie Bartels
This study aimed at looking at the frequency (T-score) and the amplitude (S-score) of fiber use during contraction of a forearm muscle, m. palmaris longus, as measured by acoustic myography (AMG). An additional aim was to relate the T- and S-scores to the recorded force obtained from a hand dynamometer. The hypothesis being that temporal and spatial summation of muscle fiber contraction in a given muscle during a given movement, can together describe a given obtained force. Force measurements were carried out on 12 healthy human subjects aged 19-68 years (6 men & 6 women), while their m...
January 2018: Physiological Reports
https://www.readbyqxmd.com/read/29332583/eating-green-shining-light-on-the-use-of-dietary-phytochemicals-as-a-modern-approach-in-the-prevention-and-treatment-of-head-and-neck-cancers
#2
Linda L Eastham, Candace M Howard, Premalatha Balachandran, David S Pasco, Pier Paolo Claudio
Enthusiasm for the use of dietary bioactive compounds as chemopreventive agents and adjuvants for current therapies has increased laboratory research conducted on several types of cancers including Head and Neck Squamous Cell Carcinoma (HNSCC). The green chemoprevention movement is a modern approach to highlight healthy lifestyle changes that aim to decrease the incidence of HNSCC. A healthy diet can be an effective way to prevent the development of oral cancers. Discovery of the naturally occurring plant based compounds called phytochemicals has facilitated the development of new treatment strategies for patients that are at risk for, or have developed HNSCC...
January 12, 2018: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/29332107/the-sleep-architecture-of-saudi-arabian-patients-with-kleine-levin-syndrome
#3
Saad M Al Shareef, Aljohara S Almeneessier, Omeima Hammad, Richard M Smith, Ahmed S BaHammam
To establish baseline sleep architecture during an acute attack of Kleine-Levin syndrome (KLS) in a cohort of Saudi Arabian KLS patients and compare these characteristics with other published cohorts. Methods: This was a retrospective cohort study of the polysomnographic characteristics of 10 typical symptomatic Saudi Arabian KLS patients attending the University Sleep Disorders Center, King Saud University, Riyadh, Saudi Arabia between 2002 and 2015. Data were captured by nocturnal polysomnography during an acute attack of hypersomnia and compared with other published cohorts identified via a systematic literature search...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332085/deep-brain-stimulation-of-the-subthalamic-nucleus-and-globus-pallidus-for-parkinson-s-disease
#4
Philip S Lee, Donald J Crammond, R Mark Richardson
The concept of deep brain stimulation (DBS) for Parkinson's disease (PD) was introduced over 20 years ago, but our understanding of the nuances of this procedure continues to improve. The average motor outcomes of internal segment of the globus pallidus (GPi) and subthalamic nucleus (STN) DBS appear to be similar, although GPi DBS may allow greater recovery of verbal fluency and may provide greater relief of depression symptoms and improvement in the quality of life, and STN DBS appears more likely to result in decrease in levodopa equivalent doses...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29332079/radiosurgical-thalamotomy
#5
Edward A Monaco Iii, Samuel S Shin, Ajay Niranjan, L Dade Lunsford
Tremor is a common movement disorder that can be disabling, and its initial treatment is in the form of medical therapies. Often patients are refractory and seek surgical intervention. Treatment options for these patients include surgical radiofrequency thalamotomy and deep brain stimulation. There are a subset of patients who, for various reasons, are not candidates for open surgical procedures, or who opt to avoid them. For these patients, radiosurgical thalamotomy is a safe and useful alternative. Herein, we provide a review of the use of radiosurgical thalamotomy for the treatment of medically refractory tremor by discussing its history, defining the technique and its indications, evaluating its efficacy, and exploring its complications and shortcomings...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29331489/modulation-of-lower-extremity-joint-stiffness-work-and-power-at-different-walking-and-running-speeds
#6
Li Jin, Michael E Hahn
Locomotion task and speed changes affect dynamic joint function. Walking and running require different coordination patterns of lower extremity joint mechanics. These coordination differences can result in measurable changes in kinematic and kinetic patterns. When locomotion speed changes, the functional role and movement strategy of each joint is altered. A deeper understanding of joint level mechanics and functional interactions will benefit rehabilitation programs and assistive device development. In this study, joint stiffness, joint mechanical work and power were assessed, as they relate to dynamic function of joints during locomotion...
January 10, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29330525/distinct-modulation-of-inactivation-by-a-residue-in-the-pore-domain-of-voltage-gated-na-channels-mechanistic-insights-from-recent-crystal-structures
#7
Rene Cervenka, Peter Lukacs, Vaibhavkumar S Gawali, Song Ke, Xaver Koenig, Lena Rubi, Touran Zarrabi, Karlheinz Hilber, Walter Sandtner, Anna Stary-Weinzinger, Hannes Todt
Inactivation of voltage-gated Na+ channels (VGSC) is essential for the regulation of cellular excitability. The molecular rearrangement underlying inactivation is thought to involve the intracellular linker between domains III and IV serving as inactivation lid, the receptor for the lid (domain III S4-S5 linker) and the pore-lining S6 segements. To better understand the role of the domain IV S6 segment in inactivation we performed a cysteine scanning mutagenesis of this region in rNav 1.4 channels and screened the constructs for perturbations in the voltage-dependence of steady state inactivation...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330315/outcome-of-preterm-infants-with-postnatal-cytomegalovirus-infection
#8
Julia Gunkel, Linda S de Vries, Marian Jongmans, Corine Koopman-Esseboom, Ingrid C van Haastert, Maria C J Eijsermans, Carolien van Stam, Bert G A van Zanten, Tom F W Wolfs, Joppe Nijman
OBJECTIVES: To assess whether preterm infants with postnatal cytomegalovirus infection develop neurologic sequelae in early childhood. METHODS: Infants <32 weeks' gestation were prospectively screened for cytomegalovirus (CMV) at term-equivalent age. Neurodevelopment was compared between CMV-positive and CMV-negative infants by using the Griffiths Mental Development Scales (GMDS) at 16 months' corrected age (CA); the Bayley Scales of Infant and Toddler Development, Third Edition or the GMDS at 24 to 30 months' CA; and the Wechsler Preschool and Primary Scale of Intelligence, Third Edition and Movement Assessment Battery for Children, Second Edition at 6 years of age...
January 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29329954/comparative-myology-of-the-ankle-of-leopardus-wiedii-and-l-geoffroyi-carnivora-felidae-functional-consistency-with-osteology-locomotor-habits-and-hunting-in-captivity
#9
Miriam M Morales, S Rocío Moyano, Agustina M Ortiz, Marcos D Ercoli, Luis I Aguado, Sergio A Cardozo, Norberto P Giannini
Leopardus wiedii (margay) is the only arboreal Neotropical felid able to climb head-first down trees, due to its ability to rotate its tarsal joint 180°. A closely related, similar-sized species, L. geoffroyi (Geoffroy's cat) exhibits more typical terrestrial habits and lacks the arboreal capabilities of L. wiedii. There is osteological evidence that supports a mechanical specialization of L. wiedii's tarsal joint for inversion, but there have been no studies on the myology of this specialization. Based on comparative gross-anatomy dissections of zeugo- and autopodial muscles related to the ankle joint of one margay specimen and two Geoffroýs cats, we identified myological specializations of L...
December 26, 2017: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/29329743/gaba-and-glutamate-in-children-with-tourette-syndrome-a-1h-mr-spectroscopy-study-at-7t
#10
E Mark Mahone, Nicolaas A Puts, Richard A E Edden, Matthew Ryan, Harvey S Singer
Tourette syndrome (TS) is characterized by presence of chronic, fluctuating motor and phonic tics. The underlying neurobiological basis for these movements is hypothesized to involve cortical-striatal-thalamo-cortical (CSTC) pathways. Two major neurotransmitters within these circuits are γ-aminobutyric acid (GABA) and glutamate. Seventy-five participants (32 with TS, 43 controls) ages 5-12 years completed 1H MRS at 7T. GABA and glutamate were measured in dorsolateral prefrontal cortex (DLPFC), ventromedial prefrontal cortex (VMPFC), premotor cortex (PMC), and striatum, and metabolites quantified using LCModel...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329534/a-large-scale-study-of-a-poultry-trading-network-in-bangladesh-implications-for-control-and-surveillance-of-avian-influenza-viruses
#11
N Moyen, G Ahmed, S Gupta, T Tenzin, R Khan, T Khan, N Debnath, M Yamage, D U Pfeiffer, G Fournie
BACKGROUND: Since its first report in 2007, avian influenza (AI) has been endemic in Bangladesh. While live poultry marketing is widespread throughout the country and known to influence AI dissemination and persistence, trading patterns have not been described. The aim of this study is to assess poultry trading practices and features of the poultry trading networks which could promote AI spread, and their potential implications for disease control and surveillance. Data on poultry trading practices was collected from 849 poultry traders during a cross-sectional survey in 138 live bird markets (LBMs) across 17 different districts of Bangladesh...
January 12, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29328985/standing-on-a-sliding-board-affects-generation-of-anticipatory-and-compensatory-postural-adjustments
#12
Bing Chen, Yun-Ju Lee, Alexander S Aruin
Postural control is compromised in the presence of body instability. We studied anticipatory and compensatory postural adjustments people use to maintain balance while standing on an unstable surface and performing voluntary arm movements. Nine healthy participants stood on a sliding board (that was either locked and as such motionless or unlocked and as such free to move in the anterior-posterior direction) and performed fast bilateral arms flexion. Arm acceleration, bilateral electromyographic activity (EMG) of the trunk and lower extremity muscles and center of pressure (COP) displacements were recorded and analyzed within the intervals typical for the anticipatory (APAs) and compensatory (CPAs) postural adjustments...
December 28, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29328011/-is-there-quality-of-life-with-locked-in-syndrome
#13
S D Limburg, J Pols, M Limburg
A 57-year-old man developed a locked-in state due to a brain stem stroke. He communicated through eye movements. The team suggested treatment should be discontinued, as there was no perspective of improvement. The family was very upset because they experienced sufficient quality of life. We investigated what 'quality of life' means. The literature shows that severely ill and completely care-dependent patients may experience high quality of life; this is called the disability paradox. Patients and families evaluate quality of life by looking for positive things to live for...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29327824/are-there-bilateral-isokinetic-shoulder-rotator-differences-in-basketball-male-players
#14
Thierry Weissland, Maryne Cozette, Clare Doyle, Antoine Gabrion
BACKGROUND: The internal (IR) and external (ER) rotator shoulder strength are often assess in the upper limb sports to prevent a risk of injuries. The purpose of this comparative study was to measure the agonist/antagonist balance of shoulder strength and to determine whether significant differences exist between the dominant and nondominant sides in basketball players compared to a control groups. METHODS: During the championship, 23 elite male-basketball players (BB) and 23 healthy males (CG) were tested bilaterally on a Cybex Norm isokinetic dynamometer in a seated position with 45° shoulder abduction in the scapular plane at 60°...
January 10, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29327823/a-previous-hamstring-injury-affects-kicking-mechanics-in-soccer-players
#15
Archit Navandar, Santiago Veiga, Gonzalo Torres, David Chorro, Enrique Navarro
BACKGROUND: Although the kicking skill is influenced by limb dominance and sex, how a previous hamstring injury affects kicking has not been studied in detail. Thus, the objective of this study was to evaluate the effect of sex and limb dominance on kicking in limbs with and without a previous hamstring injury. METHODS: 45 professional players (males: n=19, previously injured players=4, age=21.16 ± 2.00 years; females: n=19, previously injured players=10, age=22...
January 10, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29327170/the-effects-of-a-single-session-of-spinal-manipulation-on-strength-and-cortical-drive-in-athletes
#16
Thomas Lykke Christiansen, Imran Khan Niazi, Kelly Holt, Rasmus Wiberg Nedergaard, Jens Duehr, Kathryn Allen, Paul Marshall, Kemal S Türker, Jan Hartvigsen, Heidi Haavik
PURPOSE: The primary purpose of this study was to investigate whether a single session of spinal manipulation (SM) increases strength and cortical drive in the lower limb (soleus muscle) of elite Taekwondo athletes. METHODS: Soleus-evoked V-waves, H-reflex and maximum voluntary contraction (MVC) of the plantar flexors were recorded from 11 elite Taekwondo athletes using a randomized controlled crossover design. Interventions were either SM or passive movement control...
January 11, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29326867/cavitary-lung-lesion-suspicious-for-malignancy-reveals-mycobacterium-xenopi
#17
Sumit Fogla, Vaishali M Pansare, Luis G Camero, Uzma Syeda, Naveen Patil, Arun Chaudhury
We report the case of a 68-year-old gentleman who presented with musculoskeletal chest pain which appeared suddenly when he bent over with his dog. The chest pain was localized to the left lower chest and increased with movement and deep breathing. The patient did not complain weight loss, night sweat, fever or chill. He complained of mild cough, with expectoration of whitish mucus. Imaging revealed cavitary chest lesion in the right upper lobe, which was initially suspected to be lung cancer. The patient had a 50-year-old history of smoking 2 packs per day...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29326456/case-report-coronectomy-of-an-impacted-and-submerged-second-deciduous-molar
#18
M G Hussain, S K Sah, I McHenry
Coronectomy is a widely-accepted technique available for the treatment of impacted wisdom teeth. The fundamental principle is to prevent trauma to the inferior dental nerve (IDN). Many publications have demonstrated its positive outcomes but there is no literature available regarding coronectomy of deciduous teeth. This case report highlights the complex approach to managing a severely infraoccluded 85 in the mixed dentition of a 10-year-old female. The report demonstrates and discusses the combined orthodontic and oral surgical approach to prevent damage to the IDN and to allow space for orthodontic movement...
January 12, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29326295/randomised-controlled-trial-of-escitalopram-for-cervical-dystonia-with-dystonic-jerks-tremor
#19
Evelien Zoons, Jan Booij, Catherine C S Delnooz, Joke M Dijk, Yasmine E M Dreissen, Johannes H T M Koelman, Sandra M A van der Salm, Matej Skorvanek, Marenka Smit, Majid Aramideh, Henriette Bienfait, Agnita J W Boon, Jeroen W M Brans, Edo Hoogerwaard, Ad Hovestadt, Daan J Kamphuis, Alexander G Munts, Johannes D Speelman, Marina A J Tijssen
OBJECTIVE: Trials for additional or alternative treatments for cervical dystonia (CD) are scarce since the introduction of botulinum neurotoxin (BoNT). We performed the first trial to investigate whether dystonic jerks/tremor in patients with CD respond to the selective serotonin reuptake inhibitor (SSRI) escitalopram. METHODS: In a randomised, double-blind, crossover trial, patients with CD received escitalopram and placebo for 6 weeks. Treatment with BoNT was continued, and scores on rating scales regarding dystonia, psychiatric symptoms and quality of life (QoL) were compared...
January 11, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29325901/dynamic-structure-of-lower-limb-joint-angles-during-walking-post-stroke
#20
Kelley Kempski, Louis N Awad, Thomas S Buchanan, Jill S Higginson, Brian A Knarr
BACKGROUND: Variability in joint kinematics is necessary for adaptability and response to everyday perturbations; however, intrinsic neuromotor changes secondary to stroke often cause abnormal movement patterns. How these abnormal movement patterns relate to joint kinematic variability and its influence on post-stroke walking impairments is not well understood. OBJECTIVE: The purpose of this study was to evaluate the movement variability at the individual joint level in the paretic and non-paretic limbs of individuals post-stroke...
December 15, 2017: Journal of Biomechanics
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