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renal pelvis carcinoma

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https://www.readbyqxmd.com/read/29755405/dual-paraneoplastic-endocrine-syndromes-heralding-onset-of-extrapulmonary-small-cell-carcinoma-a-case-report-and-narrative-review
#1
Jill B Feffer, Natalia M Branis, Jeanine B Albu
Objective: Extrapulmonary small cell carcinoma (EPSCC) is rare and frequent metastases at presentation can complicate efforts to identify a site of origin. In particular, SCC comprises <1% of prostate cancers and has been implicated in castration resistance. Methods: Clinical, laboratory, imaging, and pathology data are presented. Results: A 56-year-old man with locally advanced prostate adenocarcinoma on androgen deprivation therapy presented with a clogged nephrostomy tube...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29737959/risk-factors-for-bladder-cancer-recurrence-survival-in-patients-with-upper-tract-urothelial-carcinoma
#2
Yu-Peng Wu, Yun-Zhi Lin, Min-Yi Lin, Ting-Ting Lin, Shao-Hao Chen, Yong Wei, Qing-Shui Zheng, Xue-Yi Xue, Ning Xu
Purpose The aim of this work was to investigate the predictive factors for bladder cancer recurrence survival (BCRS) in patients with upper-tract urothelial carcinoma (UTUC). Methods We selected patients with UTUC who underwent segmental ureterectomy (Su) or nephroureterectomy (Nu) from 2004 to 2013 from the Surveillance, Epidemiology, and End Results (SEER) database. Patients with a history of intravesical therapy for bladder cancer and bladder cancer prior to the diagnosis of UTUC were excluded. We used Kaplan-Meier analysis, log-rank tests, and Cox proportional hazards model to compare overall survival, cancer-specific survival, and BCRS...
December 1, 2017: Tumori
https://www.readbyqxmd.com/read/29731801/sarcomatoid-carcinoma-of-renal-pelvis-involving-ureter-and-renal-parenchyma-with-heterologous-osteosarcomatous-differentiation-a-case-report-and-review-of-literature
#3
Bhavya P Mohan, P L Jayalakshmy, V Letha, Suresh Bhat
Sarcomatoid carcinoma is a highgrade rare malignant tumor with both epithelial and mesenchymal components. Sarcomatoid carcinoma in the upper urinary tract is very rare. We reported here a case of sarcomatoid carcinoma of renal pelvis with osteosarcomatous differentiation, with involvement of the ureter and renal parenchyma in a 68-year-old female. Histologically, predominant pleomorphic spindle cell sarcoma component with osteoid production and urothelial carcinoma component with in situ areas were identified...
2018: Iranian Journal of Pathology
https://www.readbyqxmd.com/read/29715161/renal-pelvis-carcinoma-with-renal-vein-or-inferior-vena-cava-involvement-linked-to-early-onset-lung-metastasis-based-on-ct-scan-diagnosis
#4
Tzu-Yao Liao, Chuang-Chi Liaw, Ke-Hung Tsui, Yu-Hsiang Juan
BACKGROUND/AIM: Renal pelvis cancer with invasion of the renal vein or inferior vena cava (IVC) carries a poor prognosis. The present study investigated whether early-onset lung metastasis in these patients contributes to their poor outcome. PATIENTS AND METHODS: Data were retrospectively collected from hospitalized patients with metastatic renal pelvis urothelial cancer. The parameters used to estimate the risk of lung metastasis were based on computed tomographic (CT) scans...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29687437/coincidental-bladder-cuff-transitional-cell-carcinoma-in-nephroureterectomy-specimens-risk-factors-prognosis-and-clinical-implementation
#5
Mohamed Mohamed Elawdy, Yasser Osman, Diaa-Eldin Taha, Samer El-Halwagy, Mohsen El-Mekresh
PURPOSE: There is a lack of reporting of the bladder cuff pathology in the literature and ongoing debate regarding the role of bladder cuff excision (BCE) in the prognosis in patients with upper tract urothelial carcinoma (UTUC). We aimed to know the risk factors, the survival, and the clinical course of such pathology. MATERIALS AND METHODS: The study was retrospective, from 1983-2013 on 305 patients who had diagnosed with UTUC. Patients were managed by radical open/ laparoscopic nephroureterectomy with bladder cuff excision...
April 24, 2018: Urology Journal
https://www.readbyqxmd.com/read/29684961/-a-case-of-renal-cell-carcinoma-growing-into-the-renal-pelvis-with-a-fibrin-cap-in-the-ureter-and-bladder
#6
Tatsuro Ishikawa, Koji Izumi, Takuya Kondo, Ken Miyama, Yutaka Osada, Junnichi Ota
We present a case of renal cell carcinoma growing into the renal pelvis with a fibrin cap in the ureter and bladder. A 66-year-old man presented to our hospital with anemia and gross hematuria. Computed tomography showed a large left renal tumor and space-occupying lesions in the left renal pelvis and ureter. Cystoscopy showed a 2 cm-restiform mass protruding from the left ureteral orifice. We performed open left nephroureterectomy, and there was a 3 cm white mass with a smooth surface in the bladder. Pathological examination of the resected mass revealed clear cell carcinoma with urinary collecting system invasion and fibrin cap in the ureter and bladder...
March 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29624636/prognostic-importance-of-lymphovascular-invasion-in-urothelial-carcinoma-of-the-renal-pelvis
#7
Matthew R Danzig, Katherine Mallin, James M McKiernan, Walter M Stadler, Srikala S Sridhar, Todd M Morgan, Bernard H Bochner, Cheryl T Lee
BACKGROUND: The current study was conducted to assess the impact of lymphovascular invasion on the survival of patients with urothelial carcinoma of the renal pelvis. METHODS: Patients with urothelial carcinoma of the renal pelvis who underwent radical nephroureterectomy from 2010 through 2015 were identified in the National Cancer Data Base. Patients were characterized according to demographic and clinical factors, including pathologic tumor stage and lymphovascular invasion...
April 6, 2018: Cancer
https://www.readbyqxmd.com/read/29606134/tgr5-expression-in-normal-kidney-and-renal-neoplasms
#8
Chaohui Lisa Zhao, Ali Amin, Yiang Hui, Dongfang Yang, Weibiao Cao
BACKGROUND: The G protein-coupled bile acid receptor (TGR5) is a cell surface receptor which induces the production of intracellular cAMP and promotes epithelial-mesenchymal transition in gastric cancer cell lines. TGR5 is found in a wide variety of tissues including the kidney. However, the patterns of TGR5 expression have not been well characterized in physiologic kidney or renal neoplasms. We explore the expression of TGR5 in benign renal tissue and renal neoplasms and assess its utility as a diagnostic marker...
April 2, 2018: Diagnostic Pathology
https://www.readbyqxmd.com/read/29599345/significance-of-perioperative-chemotherapy-in-squamous-cell-carcinoma-of-the-upper-and-lower-urinary-tract
#9
Tomoyuki Makino, Kouji Izumi, Ariunbold Natsagdorj, Hiroaki Iwamoto, Suguru Kadomoto, Renato Naito, Yoshifumi Kadono, Atsushi Mizokami
BACKGROUND/AIM: To evaluate the clinicopathological characteristics and prognosis of squamous cell carcinoma (SCC) of the urinary tract (UT) urothelium, and investigate the utility of perioperative chemotherapy. PATIENTS AND METHODS: Thirty-three patients diagnosed with SCC in renal pelvis, ureter and bladder at the Kanazawa University between 2007 and 2017 were included in this retrospective study. Cancer-specific survival (CSS) rates according to cancer stage and neoadjuvant chemotherapy (NAC) were determined...
April 2018: Anticancer Research
https://www.readbyqxmd.com/read/29593918/a-case-of-polymicrobial-bacteremia-in-a-patient-undergoing-chemotherapy
#10
Kyoko Arahata, Ryo Yamaguchi, Takeshi Terashima
We report an aggressive case of polymicrobial bacteremia in a patient with renal pelvis carcinoma. A 76-year-old man developed watery diarrhea after undergoing chemotherapy. He became unconscious and went into shock. Laboratory data showed severe neutropenia, renal failure, and lactic acidosis. Chest radiography showed multiple opacities. He died despite aggressive fluid resuscitation, catecholamine administration, antibiotic treatment, and mechanical ventilation. Blood culture isolates included Escherichia coli , Klebsiella pneumoniae , Streptococcus pneumoniae , Acinetobacter baumannii , and Moraxella catarrhalis ...
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29581908/sarcomatoid-variant-of-urothelial-carcinoma-of-the-renal-pelvis-with-inferior-vena-cava-tumour-thrombus-a-case-report-and-literature-review
#11
Sameera Rashid, Mohammed Akhtar
Sarcomatoid variant of urothelial carcinoma (SVUC) of the renal pelvis is a rare entity. To the best of our knowledge, around 25 cases of this neoplasm have been reported in the literature to date, most of which were of high stage. The inferior vena cava tumour thrombus, which is a hallmark of renal cell carcinoma (RCC), may rarely be found in urothelial carcinoma of renal pelvis. In this report, a case of SVUC associated with tumour extension to inferior vena cava is documented. This association has been encountered in only one previously reported case...
2018: Case Reports in Pathology
https://www.readbyqxmd.com/read/29556581/stereotactic-body-radiation-therapy-for-medically-inoperable-clinically-localized-urothelial-carcinoma-of-the-renal-pelvis-a-case-report
#12
Jaden D Evans, Chase C Hansen, Matthew K Tollefson, Christopher L Hallemeier
No abstract text is available yet for this article.
January 2018: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29552246/amyloidosis-of-the-renal-pelvis-presenting-as-flank-pain
#13
Rachel Shikhman, Jarrod Curry, Roland Gazaille
Amyloidosis is a rare disease defined by accumulation of extracellular amyloid systemically or within a specific organ. Localized amyloidosis of the genitourinary system is extremely rare, with the predominate location being the bladder. The imaging findings are often nonspecific and mimic urothelial carcinoma. We present a 49-year-old woman with a chief complaint of flank pain. A filling defect was discovered on radiological imaging. The defect was subsequently biopsied and proven to be a primary amyloidosis of the renal pelvis...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29534942/revisiting-the-prognostic-heterogeneity-of-ajcc-stage-iv-carcinomas-of-the-upper-urinary-tract
#14
Omar Abdel-Rahman
BACKGROUND: Current staging paradigms from the American Joint Committee on Cancer (AJCC) staging system for upper urinary tract carcinomas treat locoregionally advanced (T4 and N+) and metastatic (M1) patients as a single entity (stage IV). The current study proposes a modification of the AJCC staging system where these 2 entities are separated. METHODS: The Surveillance, Epidemiology, and End Results (SEER) database (2004-2014) was accessed through SEER*Stat program...
February 22, 2018: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29534418/-application-of-narrow-band-imaging-flexible-ureteroscopy-in-the-diagnosis-treatment-and-follow-up-of-upper-tract-urothelial-carcinomas
#15
Y C Hao, C L Xiao, K Liu, Y Q Liu, L L Ma
Objective: To investigate application value of narrow-band imaging (NBI) flexible ureteroscopy in the diagnosis, treatment and follow-up of upper urinary tract transitional carcinomas (UTUC). Methods: From June 2015 to June 2017, 16 patients of UTUC were treated by flexible ureteroscopy with white light (WLI) and NBI at Department of Urology, Peking University Third Hospital , including 10 females and 6 males. The age of patients ranged from 43 to 84 years (average 68.9 years). There were 54 cases, including 16 cases with first-suspicion of cancer, and 38 cases with known of UTUC as follow-up...
March 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29520901/novel-method-for-dna-methylation-analysis-using-high-performance-liquid-chromatography-and-its-clinical-application
#16
Takuya Yotani, Yuriko Yamada, Eri Arai, Ying Tian, Masahiro Gotoh, Motokiyo Komiyama, Hiroyuki Fujimoto, Michiie Sakamoto, Yae Kanai
The aim of this study was to develop a new methodology that is suitable for DNA methylation diagnostics and to demonstrate its clinical applicability. We developed a new anion-exchange column for high-performance liquid chromatography (HPLC) with electrostatic and hydrophobic properties. Both cytosine and thymine, corresponding to methylated and unmethylated cytosine after bisulfite modification, respectively, are captured by electrostatic interaction and then discriminated from each other by their hydrophobic interactions...
March 9, 2018: Cancer Science
https://www.readbyqxmd.com/read/29489406/utility-of-pelvic-ct-for-surveillance-of-t2-t4-renal-cell-carcinoma-after-nephrectomy-with-curative-intent
#17
Andrew Kaiser, Matthew S Davenport, Khaled S Hafez, Ajjai Alva, Jason J Bailey, Isaac R Francis
OBJECTIVE: The purpose of this study was to determine whether routine pelvic imaging is necessary during postoperative surveillance of pathologic T2-T4 renal cell carcinoma after nephrectomy for curative intent. MATERIALS AND METHODS: A retrospective single-institution cohort study with 603 subjects undergoing partial or radical nephrectomy of T2-T4 renal cell carcinoma with curative intent was conducted from January 1, 2000, through December 31, 2015. Clinical and imaging (CT or MRI) follow-up findings were evaluated in a prospectively maintained registry to determine the timing and location of recurrent and metastatic disease...
May 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29487884/-ex-vivo-study-in-nephroureterectomy-specimens-defining-the-role-of-3-d-upper-urinary-tract-visualization-using-optical-coherence-tomography-and-endoluminal-ultrasound
#18
Mieke T J Bus, Paul Cernohorsky, Daniel M de Bruin, Sybren L Meijer, Geert J Streekstra, Dirk J Faber, Guido M Kamphuis, Patricia J Zondervan, Marcel van Herk, Maria P Laguna Pes, Maik J Grundeken, Martin J Brandt, Theo M de Reijke, Jean J M C H de la Rosette, Ton G van Leeuwen
Minimal invasive endoscopic treatment for upper urinary tract urothelial carcinoma (UUT-UC) is advocated in patients with low-risk disease and limited tumor volume. Diagnostic ureterorenoscopy combined with biopsy is the diagnostic standard. This study aims to evaluate two alternative diagnostic techniques for UUT-UC: optical coherence tomography (OCT) and endoluminal ultrasound (ELUS). Following nephroureterectomy, OCT, ELUS, and computed tomography (CT) were performed of the complete nephroureterectomy specimen...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29429165/-clinicopathologic-features-with-collecting-duct-carcinoma-of-kidney-report-of-10-cases
#19
J X Zhou, X R He, G X Song, Z G Zou, L H Wang, R Hu, H X Li
Objective: To study the pathological features, immunophenotypes, differential diagnoses and prognostic parameters of collecting duct carcinoma of the kidney (CDC). Methods: Clinical imaging, histopathology, immunohistochemistry, and survival data of 10 patients at First Affiliated Hospital of Nanjing Medical University from January 2009 to August 2017 were retrospectively analyzed along with a review of literatures. Results: The clinical symptoms of CDC were not specific, and image examinations showed space-occupying mass lesions...
February 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29343916/effects-of-tumor-size-and-location-on-survival-in-upper-tract-urothelial-carcinoma-after-nephroureterectomy
#20
Shreyas S Joshi, Laura L Quast, Sam S Chang, Sanjay G Patel
Introduction: Upper Tract Urothelial Carcinoma (UTUC) is a rare disease with few prognostic determinants. We sought to evaluate the impact of tumor size and location on patient survival following nephroureterectomy for UTUC. Materials and Methods: Data on 8284 patients treated with radical nephroureterectomy for UTUC in the United States between 1998 and 2011 were analyzed from the National Cancer Data Base. Univariable survivorship curves were generated based on pT stage, pN stage, grade, tumor size, and tumor site (renal pelvis vs...
January 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
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