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https://www.readbyqxmd.com/read/28422039/-urinary-tract-lymphoepithelial-carcinoma-report-of-two-cases-and-bibliographic-review
#1
Sebastian Valverde Martínez, Waleska Salcedo Mercado, Isabel Rodríguez Cruz, Sara Belén Prieto Nogal, Mario Martín Hernández, Luis Miguel Gómez Tejeda
OBJECTIVE: We report two cases of patients diagnosed with lymphoepithelioma-like carcinomas of the urinary tract. We review the literature of this rare entity. The objective is to clarify the clinical and therapeutic characteristics. METHODS: We present a retrospective review of medical records of two patients diagnosed with lymphoepithelioma-like carcinomas, one in the renal pelvis and the other in the bladder. We review the epidemiology, diagnosis and therapeutic alternatives...
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28391777/remarkable-response-to-fluorouracil-leucovorin-oxaliplatin-and-irinotecan-therapy-in-urothelial-cancer-of-the-renal-pelvis-a-case-report
#2
Takuya Tsujino, Kiyoshi Takahara, Tomohisa Matsunaga, Yuki Yoshikawa, Tomoaki Takai, Taizo Uchimoto, Kenkichi Saito, Naoki Tanda, Hajime Hirano, Hayahito Nomi, Naokazu Ibuki, Teruo Inamoto, Haruhito Azuma
BACKGROUND: No standard chemotherapy regimen for advanced urothelial cancer has been established, except for cisplatin-based regimens. We report the case of a patient with double primary cancer, urothelial carcinoma of the upper urinary tract and colorectal cancer, who underwent oxaliplatin-based chemotherapies. CASE PRESENTATION: A 56-year-old Japanese man presented to our hospital with the diagnosis of a left renal pelvic tumor and rectal cancer. Several examinations including ureteroscopic biopsy and computed tomography-guided biopsy were performed; however, the diagnosis of renal pelvic cancer could not be made...
April 10, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28329636/correlation-between-cancer-incidences-and-google-searches-in-the-united-states
#3
Mackenzie R Wehner, Kevin T Nead, Eleni Linos
IntroductionDespite being highly prevalent, keratinocyte carcinomas (basal cell and squamous cell carcinomas lack nationwide registries. Internet search data has emerged as a new method to evaluate previously difficult to quantify public health outcomes and may be useful in keratinocyte carcinoma research.ObjectiveWe aimed to evaluate whether Google search density correlated with known incidences of common cancers in the United States.MethodsWe used the Center for Disease Control's National Program of Cancer Registries ageTadjusted cancer incidences (2008T2012 ...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28314541/risk-of-subsequent-primary-kidney-cancer-after-another-malignancy-a-population-based-study
#4
Omar Abdel-Rahman
BACKGROUND: Population-based data on the development of kidney cancer as a second malignant neoplasm following the diagnosis of other common malignancies are rare. This clinical scenario has been evaluated within the Surveillance, Epidemiology, and End Results (SEER) database. MATERIALS AND METHODS: The SEER-9 database (1973-2013) was queried using the SEER*Stat program to determine the standardized incidence ratios (SIRs) of kidney cancer development following each one of 10 common invasive malignancies (colorectal, breast, prostate, lung, thyroid, corpus uteri, urinary bladder, kidney/renal pelvis, cutaneous melanoma, and non-Hodgkin lymphoma)...
February 27, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28296764/case-report-of-primary-renal-pelvis-squamous-cell-carcinoma-coexisting-with-long-standing-calculi-in-left-kidney-on-18f-fdg-pet-ct
#5
Shengming Deng, Bin Zhang, Ying Huang, Jihui Li, Shibiao Sang, Wei Zhang
RATIONALE: Primary renal pelvis squamous cell carcinoma (SCC) is an extremely rare neoplasm. In many patients, the SCC was associated with renal calculi. PATIENT CONCERNS: A 61-year-old male presented with intermittent pain at the left lumbar region for 3 days. The PET/CT images demonstrated increased F-FDG uptake in the upper pole of the left kidney and left renal hilar lymph nodes. DIAGNOSES: Pathologic examination revealed well-moderately differentiated renal pelvis SCC with lymphatic metastasis...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28251485/endoscopic-treatment-of-upper-tract-urothelial-carcinoma
#6
REVIEW
Daniel P Verges, Costas D Lallas, Scott G Hubosky, Demetrius H Bagley
PURPOSE OF REVIEW: This study aims to make the reader be aware of recent trends regarding the endoscopic management of upper tract urothelial carcinoma (UTUC) via review of the urologic literature over the past 5 years. Given the rare incidence of this disease, and the lack of level 1 evidence, systematic reviews and meta-analyses were also evaluated. Studies of importance are also considered and outlined in the annotated reference section. RECENT FINDINGS: The PubMed database was queried using the following medical subject headings (MeSH terms): "carcinoma, transitional cell," "ureter," "ureteral neoplasms," "kidney pelvis," "endoscopy," "laser therapy," "ureteroscopy," "urologic surgical procedures," and "ureteroscopes...
April 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28249616/tumor-to-tumor-metastases-papillary-thyroid-carcinoma-into-a-clear-cell-renal-cell-carcinoma
#7
Jin Soo Andy Song, S Mark Taylor, Jonathan Trites, Matthew H Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon, Robert D Hart
BACKGROUND: Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8-3.8% for papillary and 6-20% for follicular variants of well-differentiated thyroid cancers (WDTCs). In rare instances, tumor-to-tumor metastasis between two true primary neoplasms can occurs. This medical phenomenon has previously occurred as a clear cell renal cell carcinoma (CCRCC) spreading to a WDTC...
March 1, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28248052/-endoscopic-removal-of-papillary-tumors-of-upper-urinary-tract
#8
G N Akopyan, Yu G Alyaev, A Z Vinarov, L M Rapoport, M A Gazimiev, D G Tsarichenko, E V Shpot, N I Sorokin, A M Dymov, A M Pshikhachev, V Yu Lekarev, G S Akopyan
AIM: To assess the results of organ-sparing endoscopic treatment of patients with tumors of the upper urinary tract (UUT). MATERIALS AND METHODS: Twenty four patients underwent percutaneous and ureteropyeloscopic interventions for tumors of the upper urinary tract and were followed up at the Urology Clinic, I.M. Sechenov First MSMU. Retrograde removal of benign tumors of the renal pelvis and ureter (tumors sized from 5 to 35 mm), percutaneous removal of papillary carcinoma of renal pelvis of a solitary kidney, percutaneous removal of papillary carcinoma of renal pelvis of only one functioning kidney and percutaneous removal of papillary carcinoma of the lower calyx of the L-shaped kidney were performed in 21, 1, 1 and 1 patients, respectively...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28144859/pulmonary-metastasis-from-urothelial-carcinoma-of-the-upper-urinary-tract-29%C3%A2-years-after-nephrectomy
#9
Koji Kawaguchi, Toshiki Okasaka, Takayuki Fukui, Koichi Fukumoto, Shota Nakamura, Shuhei Hakiri, Naoki Ozeki, Kohei Yokoi
BACKGROUND: Late pulmonary metastasis from urothelial carcinoma (UC) of the upper urinary tract is extremely rare. CASE PRESENTATION: A 76-year-old man was referred to our hospital due to an abnormal shadow on chest X-ray. He had a history of left nephrectomy with a diagnosis of UC in the renal pelvis 29 years previously. Computed tomography showed a mass lesion in the right middle lobe of the lung that measured 4.9 cm in diameter. A transbronchial biopsy revealed the tumor to be metastatic pulmonary UC, and he underwent right middle lobectomy of the lung...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28134806/systemic-immunotherapy-for-urothelial-cancer-current-trends-and-future-directions
#10
REVIEW
Shilpa Gupta, David Gill, Austin Poole, Neeraj Agarwal
Urothelial cancer of the bladder, renal pelvis, ureter, and other urinary organs is the fifth most common cancer in the United States, and systemic platinum-based chemotherapy remains the standard of care for first-line treatment of advanced/metastatic urothelial carcinoma (UC). Until recently, there were very limited options for patients who are refractory to chemotherapy, or do not tolerate chemotherapy due to toxicities and overall outcomes have remained very poor. While the role of immunotherapy was first established in non-muscle invasive bladder cancer in the 1970s, no systemic immunotherapy was approved for advanced disease until the recent approval of a programmed death ligand-1 (PD-L1) inhibitor, atezolizumab, in patients with advanced/metastatic UC who have progressed on platinum-containing regimens...
January 27, 2017: Cancers
https://www.readbyqxmd.com/read/28106244/second-malignancy-risk-in-patients-with-bronchopulmonary-carcinoids-epidemiological-results-from-italian-network-of-cancer-registries
#11
Filippo Lococo, Carla Galeone, Claudio Sacchettini, Giovanni Leuzzi, Alfredo Cesario, Massimiliano Paci, Lucia Mangone
PURPOSE: This epidemiological study aimed to determine the prevalence and characteristics of second tumors (STs) in patients with bronchopulmonary carcinoids (BCs). METHODS: Data on neuroendocrine carcinomas (NECs) from the AIRTUM registry (1975-2011) were used for the analysis. Among 32,325 NECs, we focused our analysis on 3,205 patients (9.9%) affected by BCs. The overall ST number and incidence were calculated. The number of STs was compared with the expected cancer number in the healthy Italian population, and the standardized incidence ratio (SIR) and 95% confidence intervals were calculated...
March 24, 2017: Tumori
https://www.readbyqxmd.com/read/28103449/anatomical-templates-of-lymph-node-dissection-for-upper-tract-urothelial-carcinoma-a-systematic-review-of-the-literature
#12
Riccardo Campi, Andrea Minervini, Andrea Mari, Georgios Hatzichristodoulou, Francesco Sessa, Albero Lapini, Maurizio Sessa, Jurgen Erich Gschwend, Sergio Serni, Marco Roscigno, Marco Carini
Indications and techniques of lymph node dissection (LND) for upper tract urothelial carcinoma (UTUC) are still controversial. Areas covered: In this study, a systematic review of the English-language literature was performed up to 1 July 2016 using the Medline, Scopus, Cochrane Library and Web of Sciences databases to provide a detailed overview of the most commonly dissected surgical templates of LND for UTUC according to laterality and location of the tumor. Overall, sixteen studies were analyzed. Based on the shared experiences in the scientific literature, the LND template typically included: for right-sided tumors of the renal pelvis, upper third and middle third of the ureter, the renal hilar, paracaval, precaval and retrocaval nodes, while for left-sided tumors the renal hilar, paraaortic and preaortic nodes...
March 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28050435/mucinous-cystadenocarcinoma-in-a-horse-shoe-kidney-masquerading-as-giant-hydronephrosis-a-case-report-diagnostic-challenges-lessons-learnt-and-review-of-literature
#13
Leena Dennis Joseph, Sriram Krishnamoorthy, Rajendiran Swaminathan, Gokul Kripesh, Hariharasudhan Sekar
Primary epithelial tumour of the renal pelvis is a rare entity. So far, very few cases are reported in literature. Of these, mucin secreting adenocarcinomas are distinctly rare. However, mucinous cystadenocarcinoma, that too arising in a horse shoe kidney is extremely rare to be reported. Mucinous cystadenomas and carcinomas arising from the renal pelvis are regarded to be secondary to a metaplastic change in the urothelium. Here, we present a case of a 51-year-old male, who complained of abdominal pain, palpable abdominal mass, haematuria along with passage of mucoid material in the urine, with a very poorly functioning kidney...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28031042/transitional-cell-carcinoma-with-extension-of-the-renal-vein-and-ivc-tumor-thrombus-report-of-three-cases-and-literature-review
#14
Mingyang Li, An Shi, Wen Kong, Jin Zhang, Yonghui Chen, Jiwei Huang, Yiran Huang
BACKGROUND: Transitional cell carcinoma (TCC) originating from the renal pelvis with a venous tumor thrombus is a rare entity. However, clinicians should be aware of it because of its high malignancy and poor prognosis. CASE PRESENTATION: Here, we report three cases of pathologically confirmed TCC originating from the renal pelvis with extension into the renal vein or inferior vena cava (IVC). Of these patients, two are males and one is female (58~73 years old)...
December 28, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28005510/case-237-renal-cell-carcinoma-with-osseous-metaplasia
#15
Billy Ming Hei Lai, Solomon Yig Joon Ka, Wai Kuen Kan, Man Wah Lam, Tang Fei Lee, Yun Hoi Lui, Jennifer Lai San Khoo
History A 47-year-old man presented with palpitations and decreased exercise tolerance. A peripheral blood smear revealed anemia, thrombocytopenia, and blast cells, and a diagnosis of acute myeloid leukemia was made. Immunohistochemistry revealed positivity for cluster of differentiation (or CD) markers, which have been reported to be associated with an increased risk of extramedullary leukemic involvement. Thus, contrast material-enhanced computed tomography (CT) of the thorax, abdomen, and pelvis was requested to enable exclusion of any extramedullary extension of leukemia...
January 2017: Radiology
https://www.readbyqxmd.com/read/27994635/diagnostic-utility-of-double-immunostaining-of-a-urine-cytology-preparation-for-cytokeratin-20-p53-expression-in-a-young-woman-with-micropapillary-urothelial-carcinoma-of-the-renal-pelvis-presenting-as-an-unknown-primary-malignancy
#16
Hyun-Jung Kim, Lucky Sung, Jung-Yeon Kim, Kyeongmee Park
Atypical urine cytology (CYT) triggers a cystoscopic or another ancillary investigation that targets urothelial neoplasms. We report a case presenting as an unknown primary malignancy, which illustrated the diagnostic utility of direct double immunostaining for cytokeratin 20 (CK20)/p53 expression in a urine CYT specimen. A 42-year-old woman visited the emergency room for pain in her right lower abdominal quadrant. Computed tomography revealed postrenal obstructive hydronephrosis, and her urine CYT showed malignancy, type undetermined...
2016: CytoJournal
https://www.readbyqxmd.com/read/27987509/-preoperative-prognostic-factors-and-preoperative-risk-stratification-of-upper-tract-urothelial-carcinoma
#17
Y C Xing, G Y Xiong, D Fang, Z Zhang, L Cai, L Zhang, Z S He, X S Li, L Q Zhou
OBJECTIVE: To identify the preoperative prognostic factors of upper tract urothelial carcinoma (UTUC) and construct preoperative risk stratification system. METHODS: A retrospective study including 686 patients who were diagnosed with UTUC and received radical nephroureterectomy or partial ureterectomy in Peking University First Hospital during 2003 and 2013. RESULTS: Of the 686 UTUC patients, 303 (44.2%) were male and 383 (55.8%) female. The postoperative pathological examination showed that 203 (29...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27920701/choroidal-metastasis-as-an-unusual-initial-presentation-of-transitional-cell-carcinoma-of-the-kidney
#18
Jamal Khader, Sara Mheid, Fawzi AbuHijla, Nadi AlKarmi, Yacoub Yousef, Yazan Othman
Metastases of transitional cell carcinoma (TCC) of the renal pelvis to the eye is a very rare event, as only one previous case has been described in the literature. We present a patient with choroidal metastasis secondary to TCC of the renal pelvis, with a review of the relevant literature. A 61-year-old male presented with sudden-onset loss of vision of the left eye. Upon evaluation and assessment, the patient was found to have unilateral choroidal metastasis secondary to TCC of the renal pelvis. He is currently on palliative chemotherapy with carboplatin and gemcitabine...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27908908/double-trouble-pelvi-ureteric-junction-obstruction-and-renal-cell-carcinoma-in-right-to-left-crossed-fused-ectopia
#19
Sumit Saini, Siddharth Yadav, Brusabhanu Nayak
Crossed renal ectopia is a rare occurrence. The majority of the crossed units are fused to their ipsilateral mate. Pelvi-ureteric junction obstruction (PUJO) in crossed fused moieties has been reported very rarely. Similarly, malignancy arising in the crossed over moieties is a rare occurrence too. Only a few cases have been reported earlier. We are here reporting an unusual case with coexistent PUJO and renal cell carcinoma in the crossed over moiety of right to left crossed fused ectopia. To the best of our knowledge, this is the first reported case with both these pathologies, coexisting, in the crossed over moiety...
December 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27896135/thrombus-like-tumor-of-renal-cell-carcinoma-mimicking-transitional-cell-carcinoma-of-kidney-a-case-report
#20
Dyandra Parikesit, Chaidir A Mochtar, Budiana Tanurahardja, Sahat Matondang, Rainy Umbas, Agus Rizal Hamid
Renal cell carcinoma (RCC) is the most common malignancy of the kidney. It is not commonly form tumor thrombus in the ureter or renal pelvis. A 29-year-old woman presented with asymptomatic gross hematuria. Contrast CT study revealed a tumor suspected to be a Transitional Cell Carcinoma (TCC). However, tumor thrombus was found in the renal pelvis and ureter. We performed Nephroureterectomy, bladder cuff excision, and lymph node dissection, and the tumor was diagnosed histopathologically as RCC. We report a very rare case of thrombus-like tumor of renal cell carcinoma mimicking transitional cell carcinoma of kidney...
January 2017: Urology Case Reports
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