keyword
MENU ▼
Read by QxMD icon Read
search

Bovine Tuberculosis

keyword
https://www.readbyqxmd.com/read/28739421/whole-genome-sequencing-of-mycobacterium-bovis-to-obtain-molecular-fingerprints-in-human-and-cattle-isolates-from-baja-california-mexico
#1
Sarai Estrella Sandoval-Azuara, Ricardo Perea-Jacobo, Raquel Muñiz-Salazar, Suelee Robbe-Austerman, Alejandro Perera-Ortiz, Gilberto López-Valencia, Doris M Bravo, Alejandro Sanchez-Flores, Daniela Miranda-Guzmán, Carlos Alberto Flores-López, Roberto Zenteno-Cuevas, Rafael Laniado-Laborín, Fabiola Lafarga de la Cruz, Tod P Stuber
OBJECTIVES: To determine genetic diversity by comparing the whole genome sequences of M. bovis cattle and human isolates from Baja California. METHODS: We used a whole genome sequencing strategy to obtain the molecular fingerprints of 172 isolates of Mycobacterium bovis from Baja California, Mexico, of which 155 were isolated from cattle, and 17 were isolated from humans. We characterized spoligotypes in silico and evaluated single nucleotide polymorphism (SNP) differences between the isolates...
July 21, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28723969/matrixlysis-an-improved-sample-preparation-method-for-recovery-of-mycobacteria-from-animal-tissue-material
#2
Christoph Leth, Ashok Varadharajan, Patrick Mester, Marlis Fischaleck, Peter Rossmanith, Friedrich Schmoll, Maria Fink
Mycobacterium caprae, a member of the Mycobacterium tuberculosis complex, is the main causative agent of bovine tuberculosis in alpine regions. Bacterial culture is the gold standard in bovine tuberculosis diagnostic but takes up to twelve weeks. This increases the time and costs for stocks affected with bovine tuberculosis. Hence this study focused on the implementation of a fast and precise mycobacterial detection method and compared it with currently used methods. Matrix lysis is a chemical lysis using high concentrations of urea to solubilize bovine and red deer tissue and was used to detect even smallest amounts or non-visible lesions of mycobacteria...
2017: PloS One
https://www.readbyqxmd.com/read/28713817/generation-of-monoclonal-antibodies-against-ag85a-antigen-of-mycobacterium-tuberculosis-and-application-in-a-competitive-elisa-for-serodiagnosis-of-bovine-tuberculosis
#3
Zhengzhong Xu, Ting Hu, Aihong Xia, Xin Li, Ze Liu, Jingjing Min, Jingjing He, Chuang Meng, Yuelan Yin, Xiang Chen, Xinan Jiao
The Ag85 complex functions as the main secretory protein of Mycobacterium tuberculosis (M. tuberculosis) and BCG. This complex is composed of the proteins, Ag85A, Ag85B, and Ag85C, with Ag85A thought to play the largest role within the complex. However, the lack of commercially available monoclonal antibodies (mAbs) against Ag85A still hinders the biological and applicative research on this protein. In this study, we developed and identified anti-Ag85A mAbs, and five hybridoma cells were established. Using the indirect immunofluorescence test, we found that two anti-Ag85A mAbs did not cross-react with Ag85B and/or Ag85C...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28693300/investigation-of-bovine-tuberculosis-outbreaks-using-the-trace-back-system-and-molecular-typing-in-korean-hanwoo-beef-cattle
#4
Bok Kyung Ku, Bo-Young Jeon, Jae Myung Kim, Young-Boo Jang, Hyeyoung Lee, Jae Young Choi, Suk Chan Jung, Hyang-Mi Nam, Hun Park, Sang-Nae Cho
Bovine tuberculosis is a chronic contagious disease responsible for major agricultural economic losses. Abattoir monitoring and trace-back systems are an appropriate method to control bovine tuberculosis, particularly in beef cattle. In the present study, a trace-back system was applied to bovine tuberculosis outbreaks of Korean native Hanwoo beef cattle. Bovine tuberculosis was detected in three index beef cattle during abattoir monitoring in Jeonbuk Province, Korea, and the original herds were traced back from each index cattle...
July 10, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28686714/experimental-mycobacterium-bovis-infection-in-three-white-rhinoceroses-ceratotherium-simum-susceptibility-clinical-and-anatomical-pathology
#5
Anita L Michel, Emily P Lane, Lin-Mari de Klerk-Lorist, Markus Hofmeyr, Elisabeth M D L van der Heijden, Louise Botha, Paul van Helden, Michele Miller, Peter Buss
Tuberculosis caused by Mycobacterium bovis is endemic in the African buffalo (Syncerus caffer) population in the Kruger National Park and other conservation areas in South Africa. The disease has been diagnosed in a total of 21 free ranging or semi-free ranging wildlife species in the country with highly variable presentations in terms of clinical signs as well as severity and distribution of tuberculous lesions. Most species are spillover or dead-end hosts without significant role in the epidemiology of the disease...
2017: PloS One
https://www.readbyqxmd.com/read/28686691/use-of-fecal-volatile-organic-compound-analysis-to-discriminate-between-non-vaccinated-and-bcg-vaccinated-cattle-prior-to-and-after-mycobacterium-bovis-challenge
#6
Christine K Ellis, Somchai Rice, Devin Maurer, Randal Stahl, W Ray Waters, Mitchell V Palmer, Pauline Nol, Jack C Rhyan, Kurt C VerCauteren, Jacek A Koziel
Bovine tuberculosis is a zoonotic disease of global public health concern. Development of diagnostic tools to improve test accuracy and efficiency in domestic livestock and enable surveillance of wildlife reservoirs would improve disease management and eradication efforts. Use of volatile organic compound analysis in breath and fecal samples is being developed and optimized as a means to detect disease in humans and animals. In this study we demonstrate that VOCs present in fecal samples can be used to discriminate between non-vaccinated and BCG-vaccinated cattle prior to and after Mycobacterium bovis challenge...
2017: PloS One
https://www.readbyqxmd.com/read/28684564/draft-genome-sequences-of-three-mycobacterium-bovis-strains-identified-in-cattle-and-wildlife-in-france
#7
Maxime Branger, Amandine Hauer, Lorraine Michelet, Claudine Karoui, Thierry Cochard, Krystel De Cruz, Sylvie Henault, María Laura Boschiroli, Franck Biet
Mycobacterium bovis is the etiologic agent of bovine tuberculosis, a chronic infectious disease affecting livestock, wild animals, and sometimes humans. We report here three draft genome sequences of Mycobacterium bovis strains of spoligotypes SB0821 and SB0134, isolated from wildlife but circulating in wildlife-livestock multihost systems, and SB0121, circulating exclusively in cattle.
July 6, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28680043/molecular-epidemiology-of-mycobacterium-bovis-in-cameroon
#8
N F Egbe, A Muwonge, L Ndip, R F Kelly, M Sander, V Tanya, V Ngu Ngwa, I G Handel, A Novak, R Ngandalo, S Mazeri, K L Morgan, A Asuquo, B M de C Bronsvoort
We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201 and 179 cattle with and without bTB-like lesions respectively out of 2,346 cattle slaughtered at Bamenda, Ngaoundere, Garoua and Maroua abattoirs between 2012-2013. Two hundred and fifty-five M. bovis were isolated, identified and genotyped using deletion analysis, Hain® Genotype MTBC, spoligotyping and MIRU-VNTR...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28671497/use-of-whole-genome-sequencing-and-evaluation-of-the-apparent-sensitivity-and-specificity-of-antemortem-tuberculosis-tests-in-the-investigation-of-an-unusual-outbreak-of-mycobacterium-bovis-infection-in-a-michigan-dairy-herd
#9
Colleen S Bruning-Fann, Suelee Robbe-Austerman, John B Kaneene, Bruce V Thomsen, John D Tilden, Jean S Ray, Richard W Smith, Scott D Fitzgerald, Steven R Bolin, Daniel J O'Brien, Thomas P Mullaney, Tod P Stuber, James J Averill, David Marks
OBJECTIVE To describe use of whole-genome sequencing (WGS) and evaluate the apparent sensitivity and specificity of antemortem tuberculosis tests during investigation of an unusual outbreak of Mycobacterium bovis infection in a Michigan dairy herd. DESIGN Bovine tuberculosis (bTB) outbreak investigation. ANIMALS Cattle, cats, dog, and wildlife. PROCEDURES All cattle in the index dairy herd were screened for bTB with the caudal fold test (CFT), and cattle ≥ 6 months old were also screened with a γ-interferon (γIFN) assay...
July 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28669385/il-10-suppression-of-ifn-%C3%AE-responses-in-tuberculin-stimulated-whole-blood-from-mycobacterium-bovis-infected-cattle
#10
Michael P Sheridan, John A Browne, Mairead B Doyle, Tara Fitzsimons, Kevina McGill, Eamonn Gormley
The measurement of bovine interferon-gamma (IFN-γ) forms the basis of a diagnostic test for bovine tuberculosis where Mycobacterium bovis sensitised effector T cells produce IFN-γ following in vitro stimulation with tuberculin antigens. In cattle infected with M. bovis it is also known that the anti-inflammatory IL-10 cytokine can inhibit in vitro production of IFN-γ leading to a reduced response in the IFN-γ diagnostic test. In order to investigate this in greater detail, whole blood samples from tuberculin skin test positive and negative cattle were stimulated with bovine and avian tuberculin antigens and in parallel with a neutralising anti-IL-10 monoclonal antibody...
July 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28657858/screening-for-bovine-tuberculosis-in-african-buffalo-syncerus-caffer-in-ngorongoro-conservation-area-northern-tanzania-implications-for-public-health
#11
Bugwesa Z Katale, Robert D Fyumagwa, Eblate E Mjingo, Kuya Sayalel, Emmanuel K Batamuzi, Mecky I Matee, Julius D Keyyu, Justice Muumba, Maulid Mdaki, Erasto V Mbugi, Mark M Rweyemamu, Donald G Mpanduji
In the Ngorongoro Conservation Area (NCA), Tanzania, where wildlife and livestock interaction is intense, greater potential for intra- and interspecies disease transmission is expected. We assessed the prevalence of bovine tuberculosis in African buffalo (Syncerus caffer) residing on the valley floor of the crater in the NCA. Apparently healthy animals were randomly selected from herds in nine sites of the Ngorongoro Crater. Syncerus caffer buffalo herds were located using very high-frequency radio-aided rangers positioned in various observation points around the crater in the NCA...
June 28, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28646151/optimal-surveillance-strategies-for-bovine-tuberculosis-in-a-low-prevalence-country
#12
Kimberly VanderWaal, Eva A Enns, Catalina Picasso, Julio Alvarez, Andres Perez, Federico Fernandez, Andres Gil, Meggan Craft, Scott Wells
Bovine tuberculosis (bTB) is a chronic disease of cattle that is difficult to control and eradicate in part due to the costly nature of surveillance and poor sensitivity of diagnostic tests. Like many countries, bTB prevalence in Uruguay has gradually declined to low levels due to intensive surveillance and control efforts over the past decades. In low prevalence settings, broad-based surveillance strategies based on routine testing may not be the most cost-effective way for controlling between-farm bTB transmission, while targeted surveillance aimed at high-risk farms may be more efficient for this purpose...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28640908/evaluating-diagnostic-tests-for-bovine-tuberculosis-in-the-southern-part-of-germany-a-latent-class-analysis
#13
Valerie-Beau Pucken, Gabriela Knubben-Schweizer, Dörte Döpfer, Andreas Groll, Angela Hafner-Marx, Stefan Hörmansdorfer, Carola Sauter-Louis, Reinhard K Straubinger, Pia Zimmermann, Sonja Hartnack
Germany has been officially free of bovine tuberculosis since 1996. However, in the last years there has been an increase of bovine tuberculosis cases, particularly in the southern part of Germany, in the Allgäu region. As a consequence a one-time tuberculosis surveillance program was revisited with different premortal and postmortal tests. The aim of this paper was to estimate diagnostic sensitivities and specificities of the different tests used within this surveillance program. In the absence of a perfect test with 100% sensitivity and 100% specificity, thus in the absence of a gold standard, a Bayesian latent class approach with two different datasets was performed...
2017: PloS One
https://www.readbyqxmd.com/read/28622866/pathology-and-genetic-findings-in-a-rare-case-of-mycobacterium-caprae-infection-in-a-sow
#14
Benedetta Amato, Teresa Maria Capucchio, Elena Biasibetti, Elena Mangano, Beatrice Maria Boniotti, Lodovica Maria Pacciarini, Sergio Migliore, Maria Vitale, Michele Fiasconaro, Vincenzo Di Marco Lo Presti
Bovine tuberculosis, a reemerging zoonosis in diverse ecological scenarios, has been reported in the autochthonous Nebrodi black pig breed population used for meat production in Italy. During a routine abattoir inspection in 2013, 24 of 299 carcasses (8%) of Nebrodi black pigs presented tuberculosis-like lesions at pathologic examination. Mycobacterium bovis was isolated from 23 animals and M. caprae from a 3-year-old sow. The sow showed severe diffuse lesions involving the visceral organs, right coxofemoral joint, and mammary glands...
June 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28610788/evaluation-of-antigen-specific-interleukin-1%C3%AE-as-a-biomarker-to-detect-cattle-infected-with-mycobacterium-bovis
#15
Mahmoud M Elnaggar, Gaber S Abdellrazeq, Alaa Elsisy, Asmaa H Mahmoud, Abdelrazeq Shyboub, Martina Sester, Samy A Khaliel, Mahavir Singh, Helmy A Torky, William C Davis
Bovine tuberculosis (bTB) is a major world-wide health problem that has been difficult to control, due to the lack of an effective vaccine and limited ability of the tuberculin skin test (TST) and the ancillary whole blood interferon-gamma (IFN-γ) release assay (IGRA) to detect all infected animals. A 6 h cytokine flow cytometric IFN-γ (CFC) assay was developed in effort to overcome these limitations and expand methods for studying the mechanisms of bTB immunopathogenesis. The present study was conducted to evaluate IL-1β as a biomarker to use in conjunction with the IFN-γ CFC assay to improve the diagnostic accuracy for bTB...
July 2017: Tuberculosis
https://www.readbyqxmd.com/read/28592322/potential-for-rapid-antibody-detection-to-identify-tuberculous-cattle-with-non-reactive-tuberculin-skin-test-results
#16
Ray W Waters, Martin H Vordermeier, Shelley Rhodes, Bhagwati Khatri, Mitchell V Palmer, Mayara F Maggioli, Tyler C Thacker, Jeffrey T Nelson, Bruce V Thomsen, Suelee Robbe-Austerman, Doris M Bravo Garcia, Mark A Schoenbaum, Mark S Camacho, Jean S Ray, Javan Esfandiari, Paul Lambotte, Rena Greenwald, Adrian Grandison, Alina Sikar-Gang, Konstantin P Lyashchenko
BACKGROUND: Bovine tuberculosis (TB) control programs generally rely on the tuberculin skin test (TST) for ante-mortem detection of Mycobacterium bovis-infected cattle. RESULTS: Present findings demonstrate that a rapid antibody test based on Dual-Path Platform (DPP(®)) technology, when applied 1-3 weeks after TST, detected 9 of 11 and 34 of 52 TST non-reactive yet M. bovis-infected cattle from the US and GB, respectively. The specificity of the assay ranged from 98...
June 7, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28591268/diagnosis-of-mycobacteria-in-bovine-milk-an-overview
#17
REVIEW
Carmen Alicia Daza Bolaños, Carolina Lechinski de Paula, Simony Trevizan Guerra, Marília Masello Junqueira Franco, Márcio Garcia Ribeiro
Tuberculosis remains as the world's biggest threat. In 2014, human tuberculosis ranked as a major infectious disease by the first time, overcoming HIV death rates. Bovine tuberculosis is a chronic disease of global distribution that affects animals and can be transmitted to humans by the consumption of raw milk, representing a serious public health concern. Despite the efforts of different countries to control and eradicate bovine tuberculosis, the high negative economic impact on meat and milk production chains remains, given the decreased production efficiency (approximately 25%), the high number of condemned carcasses, and increased animal culling rates...
June 5, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28585299/mycobacterium-bovis-hosted-by-free-living-amoebae-permits-their-long-term-persistence-survival-outside-of-host-mammalian-cells-and-remain-capable-of-transmitting-disease-to-mice
#18
Andrea Sanchez-Hidalgo, Andrés Obregón-Henao, William H Wheat, Mary Jackson, Mercedes Gonzalez-Juarrero
Bovine tuberculosis (TB) is a zoonotic disease caused by Mycobacterium bovis. Despite intensive TB control campaigns, there are sporadic outbreaks of bovine TB in regions declared TB-free. It is unclear how M. bovis is able to survive in the environment for long periods of time. We hypothesized that Free-living amoebae (FLA), as ubiquitous inhabitants of soil and water, may act as long-term reservoirs of M. bovis in the environment. In our model, M. bovis would be taken up by amoebal trophozoites, which are the actively feeding, replicating and mobile form of FLA...
June 5, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28553557/factors-affecting-herd-status-for-bovine-tuberculosis-in-dairy-cattle-in-northern-thailand
#19
Tawatchai Singhla, Sukolrat Boonyayatra, Veerasak Punyapornwithaya, Kimberly L VanderWaal, Julio Alvarez, Srinand Sreevatsan, Somphorn Phornwisetsirikun, Jamnong Sankwan, Mongkol Srijun, Scott J Wells
The objective of this case-control study was to identify farm-level risk factors associated with bovine tuberculosis (bTB) in dairy cows in northern Thailand. Spatial analysis was performed to identify geographical clustering of case-farms located in Chiang Mai and Chiang Rai provinces in northern Thailand. To identify management factors affecting bTB status, a matched case-control study was conducted with 20 case-farms and 38 control-farms. Case-farms were dairy farms with at least single intradermal tuberculin test- (SIT-) reactor(s) in the farms during 2011 to 2015...
2017: Veterinary Medicine International
https://www.readbyqxmd.com/read/28532992/assessment-of-concurrent-infection-with-bovine-viral-diarrhoea-virus-bvdv-and-mycobacterium-bovis-a-herd-level-risk-factor-analysis-from-northern-ireland
#20
A W Byrne, M Guelbenzu-Gonzalo, S A J Strain, S McBride, J Graham, A Lahuerta-Marin, R Harwood, D A Graham, S McDowell
Bovine viral diarrhoea virus (BVDV) is a significant pathogen of cattle, leading to severe economic and animal-welfare impacts. Furthermore, the pathogen has been associated with impacting the progression or spread of other pathogens (e.g. Mycobacterium bovis, the causative agent of bovine tuberculosis (bTB)). During this study we investigated (i) risk factors for BVDV at a herd-level and (ii) whether there was any association between BVDV and herd-level bTB risk. The data for this study were gathered from a voluntary BVDV control programme in Northern Ireland (2013-2015) based on the identification of virus positive animals through tissue tag testing of calves...
June 1, 2017: Preventive Veterinary Medicine
keyword
keyword
96142
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"