keyword
MENU ▼
Read by QxMD icon Read
search

Analyst

keyword
https://www.readbyqxmd.com/read/28749563/a-probabilistic-framework-for-risk-analysis-of-widespread-flood-events-a-proof-of-concept-study
#1
Klaus Schneeberger, Matthias Huttenlau, Benjamin Winter, Thomas Steinberger, Stefan Achleitner, Johann Stötter
This article presents a flood risk analysis model that considers the spatially heterogeneous nature of flood events. The basic concept of this approach is to generate a large sample of flood events that can be regarded as temporal extrapolation of flood events. These are combined with cumulative flood impact indicators, such as building damages, to finally derive time series of damages for risk estimation. Therefore, a multivariate modeling procedure that is able to take into account the spatial characteristics of flooding, the regionalization method top-kriging, and three different impact indicators are combined in a model chain...
July 27, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28748975/correction-ultra-low-fouling-alkylimidazolium-modified-surfaces-for-the-detection-of-her2-in-breast-cancer-cell-lysates
#2
Alexandra Aubé, Shirley Campbell, Andreea R Schmitzer, Audrey Claing, Jean-François Masson
Correction for 'Ultra-low fouling methylimidazolium modified surfaces for the detection of HER2 in breast cancer cell lysates' by Alexandra Aubé et al., Analyst, 2017, 142, 2343-2353.
July 27, 2017: Analyst
https://www.readbyqxmd.com/read/28748567/the-hartung-knapp-modification-for-random-effects-meta-analysis-a-useful-refinement-but-are-there-any-residual-concerns
#3
Dan Jackson, Martin Law, Gerta Rücker, Guido Schwarzer
The modified method for random-effects meta-analysis, usually attributed to Hartung and Knapp and also proposed by Sidik and Jonkman, is easy to implement and is becoming advocated for general use. Here, we examine a range of potential concerns about the widespread adoption of this method. Motivated by these issues, a variety of different conventions can be adopted when using the modified method in practice. We describe and investigate the use of a variety of these conventions using a new taxonomy of meta-analysis datasets...
July 26, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28746071/toward-a-utopian-model-for-teaching-and-nonteaching-services-every-journey-begins-with-a-first-step
#4
Lisa M Bellini, Jack Ende
Nonteaching services are an imperfect step toward enabling inpatient teaching services to transition from an unregulated, natural state, driven solely by the exigencies of patient volume and throughput, to one that is more controlled and intends to achieve the proper balance between service and education. As career educators the authors prefer to view nonteaching services as critical components of an integrated system that enables the best possible patient care and learning, yet they acknowledge that, to meet the needs of patients and learners, teaching and nonteaching services alike must be truly complementary, collaborative, and integrated components of a single system...
July 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28746007/learning-and-doing-working-with-fromm-and-applying-what-i-learned
#5
Michael Maccoby
From 1960 to 1970 Erich Fromm was my teacher, analyst, and colleague. For the next ten years, we regularly corresponded about our work and views of public policy. As my analyst, Fromm had strengths and weaknesses. He influenced my research and practice on leadership and on transforming organizations to further both productivity and human development. His concepts can help us understand the current global political and cultural crisis that, while rooted in profound historic social, economic, and technological change, calls for depth psychological insights...
August 2017: Psychoanalytic Review
https://www.readbyqxmd.com/read/28741808/reconciling-disparate-data-to-determine-the-right-answer-a-grounded-theory-of-meta-analysts-reasoning-in-meta-analysis
#6
Lisa Chan, Mary Ellen Macdonald, Franco A Carnevale, Russ Steele, Ian Shrier
While the systematic review process is intended to maximize objectivity and limit researchers' biases, examples remain of discordant recommendations from meta-analyses. Current guidelines to explore discrepancies assume the variation is produced by methodological differences, and thus focus only on the study process. Since heterogeneity of interpretation also occurs when experts examine the same data, our purpose was to examine if there are 'reasoning' differences, i.e., in how information is processed and valued...
July 25, 2017: Research Synthesis Methods
https://www.readbyqxmd.com/read/28740869/comparing-sequencing-assays-and-human-machine-analyses-in-actionable-genomics-for-glioblastoma
#7
Kazimierz O Wrzeszczynski, Mayu O Frank, Takahiko Koyama, Kahn Rhrissorrakrai, Nicolas Robine, Filippo Utro, Anne-Katrin Emde, Bo-Juen Chen, Kanika Arora, Minita Shah, Vladimir Vacic, Raquel Norel, Erhan Bilal, Ewa A Bergmann, Julia L Moore Vogel, Jeffrey N Bruce, Andrew B Lassman, Peter Canoll, Christian Grommes, Steve Harvey, Laxmi Parida, Vanessa V Michelini, Michael C Zody, Vaidehi Jobanputra, Ajay K Royyuru, Robert B Darnell
OBJECTIVE: To analyze a glioblastoma tumor specimen with 3 different platforms and compare potentially actionable calls from each. METHODS: Tumor DNA was analyzed by a commercial targeted panel. In addition, tumor-normal DNA was analyzed by whole-genome sequencing (WGS) and tumor RNA was analyzed by RNA sequencing (RNA-seq). The WGS and RNA-seq data were analyzed by a team of bioinformaticians and cancer oncologists, and separately by IBM Watson Genomic Analytics (WGA), an automated system for prioritizing somatic variants and identifying drugs...
August 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28740320/rigorous-evaluation-of-chemical-measurement-uncertainty-liquid-chromatographic-analysis-methods-using-detector-response-factor-calibration
#8
Blaza Toman, Michael A Nelson, Mary Bedner
Chemical measurement methods are designed to promote accurate knowledge of a measurand or system. As such, these methods often allow elicitation of latent sources of variability and correlation in experimental data. They typically implement measurement equations that support quantification of effects associated with calibration standards and other known or observed parametric variables. Additionally, multiple samples and calibrants are usually analyzed to assess accuracy of the measurement procedure and repeatability by the analyst...
June 2017: Metrologia
https://www.readbyqxmd.com/read/28739387/effect-of-cortex-mori-on-pharmacokinetic-profiles-of-main-isoflavonoids-from-pueraria-lobata-in-rat-plasma
#9
Bingxin Xiao, Zeng Xian Sun, Shu Yang Sun, Jie Dong, Yanli Li, Shan Gao, Jie Pang, Qi Chang
ETHNOPHARMACOLOGICAL RELEVANCE: Radix pueraria (the root of pueraria lobata (Wild.) Ohwi.), which contains a class of isoflavonoids as the main active components, as well as cortex mori (the root bark of Morus Alba L), which contains abundant active alkaloids, have been employed for the treatment of diabetes in traditional Chinese medicine for centuries. In previous studies, pharmacodynamic synergistic reactions have been observed in compatible application of pueraria lobata isoflavonoids extracts (PLF) and cortex mori alkaloids extracts (CME) for inhibiting α-glycosidase activity...
July 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28736045/comparative-effectiveness-of-high-dose-versus-standard-dose-influenza-vaccination-on-numbers-of-us-nursing-home-residents-admitted-to-hospital-a-cluster-randomised-trial
#10
Stefan Gravenstein, H Edward Davidson, Monica Taljaard, Jessica Ogarek, Pedro Gozalo, Lisa Han, Vincent Mor
BACKGROUND: Immune responses to influenza vaccines decline with age, reducing clinical effectiveness. We compared the effect of the more immunogenic high-dose trivalent influenza vaccine with a standard-dose vaccine to identify the effect on reducing hospital admissions of nursing home residents in the USA. METHODS: We did a single-blind, pragmatic, comparative effectiveness, cluster-randomised trial with a 2 × 2 factorial design. Medicare-certified nursing homes in the USA located within 50 miles of a Centers for Disease Control and Prevention influenza reporting city were recruited, so long as the facilities were not located in a hospital, had more than 50 long-stay residents, had less than 20% of the population aged under 65 years, and were not already planning to administer the high-dose influenza vaccine to residents...
July 20, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28728054/an-artificial-neural-network-system-to-identify-alleles-in-reference-electropherograms
#11
Duncan Taylor, Ash Harrison, David Powers
Electropherograms are produced in great numbers in forensic DNA laboratories as part of everyday criminal casework. Before the results of these electropherograms can be used they must be scrutinised by analysts to determine what the identified data tells them about the underlying DNA sequences and what is purely an artefact of the DNA profiling process. This process of interpreting the electropherograms can be time consuming and is prone to subjective differences between analysts. Recently it was demonstrated that artificial neural networks could be used to classify information within an electropherogram as allelic (i...
July 8, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28722247/left-ventricular-function-and-regional-strain-with-subtly-tagged-steady-state-free-precession-feature-tracking
#12
Eric M Schrauben, Brett R Cowan, Andreas Greiser, Alistair A Young
PURPOSE: To provide regional strain and ventricular volume from a single acquisition, using subtly tagged steady-state free precession (SubTag SSFP) feature tracking. MATERIALS AND METHODS: The effects on regional strain of tag strength in gradient recalled echo (GRE) tagging, flip angle in untagged balanced SSFP, and both in SubTag SSFP were examined in the mid left ventricle of 15 healthy volunteers at 3T. Optimal parameters were determined from varying both tag strength and SSFP flip angle using full tag saturation GRE as the reference standard...
July 19, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28716108/esoteric-connective-tissue-therapy-for-chronic-low-back-pain-to-reduce-pain-and-improve-functionality-and-general-well-being-compared-with-physiotherapy-study-protocol-for-a-randomised-controlled-trial
#13
Christoph Schnelle, Steffen Messerschmidt, Eunice J Minford, Kate Greenaway-Twist, Maxine Szramka, Marianna Masiorski, Michelle Sheldrake, Mark Jones
BACKGROUND: Low back pain causes more global disability than any other condition. Once the acute pain becomes chronic, about two-thirds of sufferers will not fully recover after 1-2 years. There is a paucity of effective treatments for non-specific, chronic low back pain. It has been noted that low back pain is associated with changes in the connective tissue in the affected area, and a very low-impact treatment, Esoteric Connective Tissue Therapy (ECTT), has been developed to restore flexibility in connective tissue...
July 17, 2017: Trials
https://www.readbyqxmd.com/read/28714407/update-of-standard-practices-for-new-method-validation-in-forensic-toxicology
#14
Sarah M R Wille, Wim Coucke, Thierry De Baere, Frank T Peters
: International agreement concerning validation guidelines is important as reporting reliable analytical data is the backbone of forensic bioanalytical research and applications. Guidelines such as those provided by the US Food and Drug Administration (FDA), the European Medicines Agency (EMA), the German speaking Gesellschaft für Toxikologie und Forensische Chemie (GTFCH) and the Scientific Working Group of Forensic Toxicology (SWGTOX) provide a standard for fundamental validation parameters such as selectivity, matrix effects, method limits, calibration, accuracy and stability, as well as other parameters such as carryover, dilution integrity and incurred sample reanalysis...
July 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28709406/using-structural-equation-modeling-for-network-meta-analysis
#15
Yu-Kang Tu, Yun-Chun Wu
BACKGROUND: Network meta-analysis overcomes the limitations of traditional pair-wise meta-analysis by incorporating all available evidence into a general statistical framework for simultaneous comparisons of several treatments. Currently, network meta-analyses are undertaken either within the Bayesian hierarchical linear models or frequentist generalized linear mixed models. Structural equation modeling (SEM) is a statistical method originally developed for modeling causal relations among observed and latent variables...
July 14, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28707154/personality-and-the-intergenerational-transmission-of-educational-attainment-evidence-from-germany
#16
Renee Ryberg, Shawn Bauldry, Michael A Schultz, Annekatrin Steinhoff, Michael Shanahan
Research based in the United States, with its relatively open educational system, has found that personality mediates the relationship between parents' and child's educational attainment and this mediational pattern is especially beneficial to students from less-educated households. Yet in highly structured, competitive educational systems, personality characteristics may not predict attainment or may be more or less consequential at different points in the educational career. We examine the salience of personality in the educational attainment process in the German educational system...
July 13, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28705058/standardized-approach-for-roi-based-measurements-of-proton-density-fat-fraction-and-r2-in-the-liver
#17
Camilo A Campo, Diego Hernando, Tilman Schubert, Candice A Bookwalter, Andrew J Van Pay, Scott B Reeder
OBJECTIVE: The purpose of this study was to evaluate the reproducibility (interreviewer agreement) and repeatability (intrareviewer agreement) of ROI sampling strategies to measure chemical shift-encoded (CSE) MRI-based liver proton density fat fraction (PDFF) and R2* (1 / T2*). A secondary purpose was to standardize ROI-based liver PDFF and R2* measurements by providing a compromise between measurement reproducibility and repeatability and time burden for image analysts. MATERIALS AND METHODS: CSE data from two cohorts were retrospectively analyzed...
July 13, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28691578/a-hybrid-clustering-and-classification-approach-for-predicting-crash-injury-severity-on-rural-roads
#18
Seyed Hessam-Allah Hasheminejad, Mohsen Zahedi, Seyed Mohammad Hossein Hasheminejad
As a threat for transportation system, traffic crashes have a wide range of social consequences for governments. Traffic crashes are increasing in developing countries and Iran as a developing country is not immune from this risk. There are several researches in the literature to predict traffic crash severity based on artificial neural networks (ANNs), support vector machines and decision trees. This paper attempts to investigate the crash injury severity of rural roads by using a hybrid clustering and classification approach to compare the performance of classification algorithms before and after applying the clustering...
July 10, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28686809/decision-making-in-nice-single-technological-appraisals-how-does-nice-incorporate-patient-perspectives
#19
Ferhana Hashem, Michael W Calnan, Patrick R Brown
CONTEXT: The National Institute for Health and Care Excellence (NICE) has an explicit mandate to include patient and public involvement in the appraisal of medicines to be available for funding on the NHS. NICE involves an appraisal committee who are required to take on board experiential evidence from patient experts alongside population-based evidence on clinical and cost-effectiveness when making a decision whether to fund a drug. OBJECTIVE: This paper considers how NICE Single Technological Appraisal (STA) committees attempt to incorporate the views of patients in making decisions about funding medicines on the NHS...
July 7, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28684380/quantum-gravity-and-taoist-cosmology-exploring-the-ancient-origins-of-phenomenological-string-theory
#20
REVIEW
Steven M Rosen
This paper carries forward the author's contribution to PBMP's previous special issue on Integral Biomathics (Rosen 2015). In the earlier paper, the crisis in contemporary theoretical physics was described and it was demonstrated that the problem can be addressed effectively only by shifting the foundations of physics from objectivist Cartesian philosophy to phenomenological philosophy. To that end, a phenomenological string theory was proposed based on qualitative topology and hypercomplex numbers. The current presentation takes this further by delving into the ancient Chinese origin of phenomenological string theory...
July 3, 2017: Progress in Biophysics and Molecular Biology
keyword
keyword
96140
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"