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https://www.readbyqxmd.com/read/29771314/use-of-bibloc-and-monobloc-oral-appliances-in-obstructive-sleep-apnoea-a-multicentre-randomized-blinded-parallel-group-equivalence-trial
#1
Göran Isacsson, Eva Nohlert, Anette M C Fransson, Anna Bornefalk-Hermansson, Eva Wiman Eriksson, Eva Ortlieb, Livia Trepp, Anna Avdelius, Magnus Sturebrand, Clara Fodor, Thomas List, Mohamad Schumann, Åke Tegelberg
Background: The clinical benefit of bibloc over monobloc appliances in treating obstructive sleep apnoea (OSA) has not been evaluated in randomized trials. We hypothesized that the two types of appliances are equally effective in treating OSA. Objective: To compare the efficacy of monobloc versus bibloc appliances in a short-term perspective. Patients and methods: In this multicentre, randomized, blinded, controlled, parallel-group equivalence trial, patients with OSA were randomly assigned to use either a bibloc or a monobloc appliance...
May 16, 2018: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29766747/a-seat-around-the-table-participatory-data-analysis-with-people-living-with-dementia
#2
Charlotte L Clarke, Heather Wilkinson, Julie Watson, Jane Wilcockson, Lindsay Kinnaird, Toby Williamson
The involvement of "people with experience" in research has developed considerably in the last decade. However, involvement as co-analysts at the point of data analysis and synthesis has received very little attention-in particular, there is very little work that involves people living with dementia as co-analysts. In this qualitative secondary data analysis project, we (a) analyzed data through two theoretical lenses: Douglas's cultural theory of risk and Tronto's Ethic of Care, and (b) analyzed data in workshops with people living with dementia...
May 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29762095/ct-based-visual-classification-of-emphysema-association-with-mortality-in-the-copdgene-study
#3
David A Lynch, Camille M Moore, Carla Wilson, Dipti Nevrekar, Theodore Jennermann, Stephen M Humphries, John H M Austin, Philippe A Grenier, Hans-Ulrich Kauczor, MeiLan K Han, Elizabeth A Regan, Barry J Make, Russell P Bowler, Terri H Beaty, Douglas Curran-Everett, John E Hokanson, Jeffrey L Curtis, Edwin K Silverman, James D Crapo
Purpose To determine whether visually assessed patterns of emphysema at CT might provide a simple assessment of mortality risk among cigarette smokers. Materials and Methods Of the first 4000 cigarette smokers consecutively enrolled between 2007 and 2011 in this COPDGene study, 3171 had data available for both visual emphysema CT scores and survival. Each CT scan was retrospectively visually scored by two analysts using the Fleischner Society classification system. Severity of emphysema was also evaluated quantitatively by using percentage lung volume occupied by low-attenuation areas (voxels with attenuation of -950 HU or less) (LAA-950)...
May 15, 2018: Radiology
https://www.readbyqxmd.com/read/29752251/the-importance-of-nonlinear-transformations-use-in-medical-data-analysis
#4
Netta Shachar, Alexis Mitelpunkt, Tal Kozlovski, Tal Galili, Tzviel Frostig, Barak Brill, Mira Marcus-Kalish, Yoav Benjamini
BACKGROUND: The accumulation of data and its accessibility through easier-to-use platforms will allow data scientists and practitioners who are less sophisticated data analysts to get answers by using big data for many purposes in multiple ways. Data scientists working with medical data are aware of the importance of preprocessing, yet in many cases, the potential benefits of using nonlinear transformations is overlooked. OBJECTIVE: Our aim is to present a semi-automated approach of symmetry-aiming transformations tailored for medical data analysis and its advantages...
May 11, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29750430/a-practical-guide-to-conducting-a-systematic-review-and-meta-analysis-of-health-state-utility-values
#5
Stavros Petrou, Joseph Kwon, Jason Madan
Economic analysts are increasingly likely to rely on systematic reviews and meta-analyses of health state utility values to inform the parameter inputs of decision-analytic modelling-based economic evaluations. Beyond the context of economic evaluation, evidence from systematic reviews and meta-analyses of health state utility values can be used to inform broader health policy decisions. This paper provides practical guidance on how to conduct a systematic review and meta-analysis of health state utility values...
May 10, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29750350/living-in-two-worlds-how-jungian-am-i
#6
Helen Morgan
As a so-called 'Developmental Jungian' the author of this paper was raised bilingual - speaking both psychoanalytic and Jungian languages. Early on in her training an analysand brought a dream which seemed to capture an inherent tension regarding the analyst's role in the analytic relationship. The paper is a personal exploration of the potentially creative nature of this tension through focussing on the dream and the work with the dreamer.
June 2018: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/29750345/paradoxical-affinities-otherness-and-ambivalence-as-creative-pathways
#7
Jan Wiener
Referring to her own background as the child of Jewish refugees forced to leave their countries of origin before the second World War, the author describes how her attitude towards Jung and his ideas has evolved. The role of paradoxical affinities that have affected the author's life and identity as a Jungian analyst are considered, alongside the impact of experiences of otherness whilst supervising and teaching abroad, particularly in Eastern Europe.
June 2018: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/29750344/introduction-to-special-edition-of-jap-on-the-who-is-my-jung-conference-held-at-the-british-library-in-october-2017-to-mark-the-40-th-anniversary-of-the-foundation-of-the-association-of-jungian-analysts-aja
#8
Ruth Williams
The paper reviews the processes which went into the creation of an exceptionally comprehensive conference on Jungian analysis and psychology. The conference brought together all five of the constituent societies based in London of the International Association for Analytical Psychology (IAAP). The personal nature of the conference contributions is highlighted together with observations about the passage from spoken to written modes. The idea of 'conference space' is reviewed and this leads to a discussion of the often overlooked benign role of conferences in professional life...
June 2018: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/29743081/residential-scene-classification-for-gridded-population-sampling-in-developing-countries-using-deep-convolutional-neural-networks-on-satellite-imagery
#9
Robert F Chew, Safaa Amer, Kasey Jones, Jennifer Unangst, James Cajka, Justine Allpress, Mark Bruhn
BACKGROUND: Conducting surveys in low- and middle-income countries is often challenging because many areas lack a complete sampling frame, have outdated census information, or have limited data available for designing and selecting a representative sample. Geosampling is a probability-based, gridded population sampling method that addresses some of these issues by using geographic information system (GIS) tools to create logistically manageable area units for sampling. GIS grid cells are overlaid to partition a country's existing administrative boundaries into area units that vary in size from 50 m × 50 m to 150 m × 150 m...
May 9, 2018: International Journal of Health Geographics
https://www.readbyqxmd.com/read/29742125/optimized-generation-of-high-resolution-phantom-images-using-cgan-application-to-quantification-of-ki67-breast-cancer-images
#10
Caglar Senaras, Muhammad Khalid Khan Niazi, Berkman Sahiner, Michael P Pennell, Gary Tozbikian, Gerard Lozanski, Metin N Gurcan
In pathology, Immunohistochemical staining (IHC) of tissue sections is regularly used to diagnose and grade malignant tumors. Typically, IHC stain interpretation is rendered by a trained pathologist using a manual method, which consists of counting each positively- and negatively-stained cell under a microscope. The manual enumeration suffers from poor reproducibility even in the hands of expert pathologists. To facilitate this process, we propose a novel method to create artificial datasets with the known ground truth which allows us to analyze the recall, precision, accuracy, and intra- and inter-observer variability in a systematic manner, enabling us to compare different computer analysis approaches...
2018: PloS One
https://www.readbyqxmd.com/read/29741960/ecological-interface-design-for-computer-network-defense
#11
Kevin B Bennett, Adam Bryant, Christen Sushereba
OBJECTIVE: A prototype ecological interface for computer network defense (CND) was developed. BACKGROUND: Concerns about CND run high. Although there is a vast literature on CND, there is some indication that this research is not being translated into operational contexts. Part of the reason may be that CND has historically been treated as a strictly technical problem, rather than as a socio-technical problem. METHODS: The cognitive systems engineering (CSE)/ecological interface design (EID) framework was used in the analysis and design of the prototype interface...
May 1, 2018: Human Factors
https://www.readbyqxmd.com/read/29741570/caver-analyst-2-0-analysis-and-visualization-of-channels-and-tunnels-in-protein-structures-and-molecular-dynamics-trajectories
#12
Adam Jurcik, David Bednar, Jan Byska, Sergio M Marques, Katarina Furmanova, Lukas Daniel, Piia Kokkonen, Jan Brezovsky, Ondrej Strnad, Jan Stourac, Antonin Pavelka, Martin Manak, Jiri Damborsky, Barbora Kozlikova
Motivation: Studying the transport paths of ligands, solvents, or ions in transmembrane proteins and proteins with buried binding sites is fundamental to the understanding of their biological function. A detailed analysis of the structural features influencing the transport paths is also important for engineering proteins for biomedical and biotechnological applications. Results: CAVER Analyst 2.0 is a software tool for quantitative analysis and real-time visualization of tunnels and channels in static and dynamic structures...
May 8, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29733301/applying-intelligent-algorithms-to-automate-the-identification-of-error-factors
#13
Haizhe Jin, Qingxing Qu, Masahiko Munechika, Masataka Sano, Chisato Kajihara, Vincent G Duffy, Han Chen
OBJECTIVES: Medical errors are the manifestation of the defects occurring in medical processes. Extracting and identifying defects as medical error factors from these processes are an effective approach to prevent medical errors. However, it is a difficult and time-consuming task and requires an analyst with a professional medical background. The issues of identifying a method to extract medical error factors and reduce the extraction difficulty need to be resolved. METHODS: In this research, a systematic methodology to extract and identify error factors in the medical administration process was proposed...
May 3, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29732922/patient-perspectives-on-a-text-messaging-program-to-support-asthma-management-a-qualitative-study
#14
Reina Doyle, Karen Albright, Laura P Hurley, Catia Chávez, Melanie Stowell, Suzanne Dircksen, Edward P Havranek, Mark Anderson
INTRODUCTION: This study investigated participants' acceptance of a short messaging service (SMS) intervention designed to support asthma management, including suggestions regarding program delivery and message content. METHODS: Individual and group interviews were conducted with patients from a safety-net health care system in Denver, Colorado. Eligible participants were English or Spanish speakers between the ages of 13 and 40 years, with diagnosed persistent asthma...
May 1, 2018: Health Promotion Practice
https://www.readbyqxmd.com/read/29726412/the-effect-of-latent-binary-variables-on-the-uncertainty-of-the-prediction-of-a-dichotomous-outcome-using-logistic-regression-based-propensity-score-matching
#15
Szabolcs Szekér, Ágnes Vathy-Fogarassy
Logistic regression based propensity score matching is a widely used method in case-control studies to select the individuals of the control group. This method creates a suitable control group if all factors affecting the output variable are known. However, if relevant latent variables exist as well, which are not taken into account during the calculations, the quality of the control group is uncertain. In this paper, we present a statistics-based research in which we try to determine the relationship between the accuracy of the logistic regression model and the uncertainty of the dependent variable of the control group defined by propensity score matching...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29725046/unsupervised-scalable-statistical-method-for-identifying-influential-users-in-online-social-networks
#16
A Azcorra, L F Chiroque, R Cuevas, A Fernández Anta, H Laniado, R E Lillo, J Romo, C Sguera
Billions of users interact intensively every day via Online Social Networks (OSNs) such as Facebook, Twitter, or Google+. This makes OSNs an invaluable source of information, and channel of actuation, for sectors like advertising, marketing, or politics. To get the most of OSNs, analysts need to identify influential users that can be leveraged for promoting products, distributing messages, or improving the image of companies. In this report we propose a new unsupervised method, Massive Unsupervised Outlier Detection (MUOD), based on outliers detection, for providing support in the identification of influential users...
May 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29724076/greening-reversed-phase-liquid-chromatography-methods-using-alternative-solvents-for-pharmaceutical-analysis
#17
REVIEW
Moussa Yabré, Ludivine Ferey, Issa Touridomon Somé, Karen Gaudin
The greening of analytical methods has gained increasing interest in the field of pharmaceutical analysis to reduce environmental impacts and improve the health safety of analysts. Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most widely used analytical technique involved in pharmaceutical drug development and manufacturing, such as the quality control of bulk drugs and pharmaceutical formulations, as well as the analysis of drugs in biological samples. However, RP-HPLC methods commonly use large amounts of organic solvents and generate high quantities of waste to be disposed, leading to some issues in terms of ecological impact and operator safety...
May 2, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29723427/a-robust-approach-to-risk-assessment-based-on-species-sensitivity-distributions
#18
Gianna S Monti, Peter Filzmoser, Roland C Deutsch
The guidelines for setting environmental quality standards are increasingly based on probabilistic risk assessment due to a growing general awareness of the need for probabilistic procedures. One of the commonly used tools in probabilistic risk assessment is the species sensitivity distribution (SSD), which represents the proportion of species affected belonging to a biological assemblage as a function of exposure to a specific toxicant. Our focus is on the inverse use of the SSD curve with the aim of estimating the concentration, HCp, of a toxic compound that is hazardous to p% of the biological community under study...
May 3, 2018: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29723300/increased-resistance-to-sudden-noise-by-audio-stimulation-during-early-ontogeny-in-german-shepherd-puppies
#19
Helena Chaloupková, Ivona Svobodová, Pavel Vápeník, Luděk Bartoš
The period of early ontogeny constitutes a time when the physical immaturity of an organism is highly susceptible to external stimuli. Thus, early development plays a major role in shaping later adult behavior. The aim of the study was to check whether stimulating puppies at this early stage in life with sound would improve their responsiveness towards unfamiliar noises during the selection process of the police behavioral test for puppies. The cohort comprised 37 puppies from the litters of three mothers. At the commencement of the experiment the dogs were aged 16 days, rising to the age of 32 days at its close...
2018: PloS One
https://www.readbyqxmd.com/read/29719309/capabilities-and-advantages-of-cloud-computing-in-the-implementation-of-electronic-health-record
#20
Maryam Ahmadi, Nasim Aslani
Background: With regard to the high cost of the Electronic Health Record (EHR), in recent years the use of new technologies, in particular cloud computing, has increased. The purpose of this study was to review systematically the studies conducted in the field of cloud computing. Methods: The present study was a systematic review conducted in 2017. Search was performed in the Scopus, Web of Sciences, IEEE, Pub Med and Google Scholar databases by combination keywords...
2018: Acta Informatica Medica: AIM
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