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Miguel José Francisco, Antonio Rahal, Fabio Augusto Cardillo Vieira, Paulo Savoia Dias da Silva, Marcelo Buarque de Gusmão Funari
Ultrasound examination of the chest has advanced in recent decades. This imaging modality is currently used to diagnose several pathological conditions and provides qualitative and quantitative information. Acoustic barriers represented by the aerated lungs and the bony framework of the chest generate well-described sonographic artifacts that can be used as diagnostic aids. The normal pleural line and A, B, C, E and Z lines (also known as false B lines) are artifacts with specific characteristics. Lung consolidation and pneumothorax sonographic patterns are also well established...
July 2016: Einstein
Ana Paula Limongi Richardelli Veloso, Karla Garcez Cusmanich
Background: Obesity can affect the thorax, diaphragm, and alterations in respiratory function even if the lungs are within normality. The respiratory compliance is very reduced by the increase in fat mass. Aim: To evaluate the effect of the physical therapeutic respiratory exercises on the thoracoabdominal mobility of obese individuals in pre-bariatric surgery. Methods: Cross-sectional and descriptive study, which used the cirtometry (axillary, xiphoid and abdominal) to evaluate the mobility of 74 individuals, 27 men and 47 women, in pre-bariatric surgery, assisted by the team EMAD, after eight weeks of physiotherapy, following a protocol of exercises, reevaluating and compared the measures pre and post intervention...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Vedat Bakan, Ergül Belge Kurutaş, Harun Çıralık, Mustafa Gül, Ahmet Çelik
BACKGROUND: The present objective was to investigate endogen erythropoietin (EPO) level and relationship to oxidative stress within the first 24 hours of blunt chest trauma-induced pulmo-nary contusion (PCn) in a rat model. METHODS: Thirty-five rats were divided into 3 groups. In the baseline control group (BC, n=7), rats were uninjured and untreated. In the positive control group (PC, n=21) rats were injured but untreated. In the EPO-24 group (n=7), rats were injured and a single dose of intra-peritoneal EPO (5000 IU/kg) was administered immediately after lung injury...
July 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
Ana Muñoz-Vera, Jose Matías Peñas Castejón, Gregorio García
The effects of an abandoned mining area, exploited for centuries in the mining district of Cartagena-La Union, result in a continuous supply of heavy metals into the Mar Menor coastal lagoon after rain episodes. As a consequence, concentration of trace elements in water column and sediments of this ecosystem is usually higher than in other areas. For monitoring ecosystem health, this study assessed the ability of Rhizostoma pulmo to bioaccumulate trace elements. A total of 57 individuals were sampled at eight different sampling stations during the summer of 2012...
September 15, 2016: Marine Pollution Bulletin
Burak Derkus, Yavuz Emre Arslan, Kaan C Emregul, Emel Emregul
In the present study, we describe the sonochemical isolation of nano-sized spherical hydroxyapatite (nHA) from egg shell and application towards thrombin aptasensing. In addition to the sonochemical method, two conventional methods present in literature were carried out to perform a comparative study. Various analysis methods including Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), Energy-Dispersive Analysis of X-Rays (EDAX), and Thermal Gravimetric Analysis (TGA) have been applied for the characterization of nHA and its nanocomposite with marine-derived collagen isolated from Rhizostoma pulmo jellyfish...
September 1, 2016: Talanta
P Del Negro, S Ciriaco, B Cataletto, G M Delogu, F Kokelj
Following in-depth analysis and examination, jellyfish toxins have been found to consist of a mixture of proteins, carbohydrates, and other non-proteinaceous components. What remains to be clarified is the specific chemical nature of jellyfish toxins due to their heat lability. This paper reviews current knowledge of the toxic properties of the most common Mediterranean scyphozoans (A. aurita, C. hysoscella, C. tuberculata, P. noctiluca, R. pulmo) and the activity of their venom.
May 5, 2016: Central Nervous System Agents in Medicinal Chemistry
Wakako Fukuda, Mari Chiyoya, Satoshi Taniguchi, Kazuyuki Daitoku, Ikuo Fukuda
PURPOSE: The risk of venous thromboembolism (VTE) is high during pregnancy. Although most patients with VTE are safely treated via medications, the optimal treatment for massive pulmonary embolism remains controversial. To evaluate the safety and efficacy of VTE management during pregnancy, we report our single center experience of treating VTE in pregnant women. METHODS: Case records were retrospectively reviewed from seven patients who underwent treatment for venous thromboembolism between 2002 and 2014...
June 2016: General Thoracic and Cardiovascular Surgery
Giuseppe Catalfo, Luciana Crea, Tiziana Lo Castro, Francesca Magnano San Lio, Giuseppe Minutolo, Gherardo Siscaro, Noemi Vaccino, Nunzio Crimi, Eugenio Aguglia
BACKGROUND: Several clinical studies suggest common underlying pathogenetic mechanisms of COPD and depressive/anxiety disorders. We aim to evaluate psychopathological and physical effects of aerobic exercise, proposed in the context of pulmonary rehabilitation, in a sample of COPD patients, through the correlation of some psychopathological variables and physical/pneumological parameters. METHODS: Fifty-two consecutive subjects were enrolled. At baseline, the sample was divided into two subgroups consisting of 38 depression-positive and 14 depression-negative subjects according to the Hamilton Depression Rating Scale (HAM-D)...
2016: International Journal of Chronic Obstructive Pulmonary Disease
Yu-Min Sun, Jun Wang, Xing-Biao Qiu, Fang Yuan, Ruo-Gu Li, Ying-Jia Xu, Xin-Kai Qu, Hong-Yu Shi, Xu-Min Hou, Ri-Tai Huang, Song Xue, Yi-Qing Yang
Congenital heart disease (CHD) is the most common developmental abnormality, and is the leading noninfectious cause of mortality in neonates. Increasing evidence demonstrates that genetic defects play an important role in the pathogenesis of CHD. However, CHD exhibits substantial heterogeneity, and the genetic determinants for CHD remain unknown in the overwhelming majority of cases. In the current study, the coding exons and flanking introns of the HAND2 gene, which encodes a basic helix-loop-helix transcription factor essential for normal cardiovascular development, were sequenced in 192 unrelated patients with CHD, and a novel heterozygous mutation, p...
2016: G3: Genes—Genomes—Genetics
Gang Yang, Bing Yang, Youquan Wei, Fengxiang Zhang, Weizhu Ju, Hongwu Chen, Mingfang Li, Kai Gu, Yazhou Lin, Benqi Wang, Kejiang Cao, Pipin Kojodjojo, Minglong Chen
BACKGROUND: The high incidence of postprocedural atrial tachycardia reduces the absolute arrhythmia-free success rate of extensive ablation strategies to treat nonparoxysmal atrial fibrillation (NPAF). We hypothesized that a strategy of targeting low-voltage zones and sites with abnormal electrograms during sinus rhythm (SR-AEs) in the left atrium after circumferential pulmonary vein isolation and cavotricuspid isthmus ablation in patients with NPAF is superior. METHODS AND RESULTS: A total of 86 consecutive patients with NPAF were enrolled in study group...
February 2016: Circulation. Arrhythmia and Electrophysiology
Thenappan Thenappan, Kurt W Prins, Marc R Pritzker, John Scandurra, Karl Volmers, E Kenneth Weir
The normal pulmonary circulation is a low-pressure, high-compliance system. Pulmonary arterial compliance decreases in the presence of pulmonary hypertension because of increased extracellular matrix/collagen deposition in the pulmonary arteries. Loss of pulmonary arterial compliance has been consistently shown to be a predictor of increased mortality in patients with pulmonary hypertension, even more so than pulmonary vascular resistance in some studies. Decreased pulmonary arterial compliance causes premature reflection of waves from the distal pulmonary vasculature, leading to increased pulsatile right ventricular afterload and eventually right ventricular failure...
February 2016: Annals of the American Thoracic Society
L Fidler, K J Keen, Z Touma, S Mittoo
OBJECTIVES: This study examines the effect of pulmonary disease on patient-reported outcomes (PROs) and patient-performed outcome (PPO) in systemic lupus erythematosus (SLE) patients at a single tertiary referral center. METHODS: Pulmonary function tests (PFTs), chest imaging, SLE-related damage, and disease activity were examined in 110 SLE patients. Presence was noted of abnormal PFTs, pleural disease, pulmonary hypertension (PH), pulmonary infarction, interstitial lung disease (ILD), and shrinking lung syndrome (SLS)...
August 2016: Lupus
Lalita Fernandes, Nandani Gulati, Anthony M Mesquita, Mahesh Sardesai, Yasmin Fernandes
BACKGROUND AND OBJECTIVES: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with small airway inflammation and emphysema. Emphysema is permanent enlargement of air spaces distal to terminal bronchioles accompanied by destruction of alveolar walls. These morphological changes can be studied on quantitative computed tomography (CT). METHODS: Thirty-four patients diagnosed to have COPD as per Global Initiative for Chronic Obstructive Lung Disease guidelines underwent chest CT using full inspiration with low dose radiation protocol...
July 2015: Indian Journal of Chest Diseases & Allied Sciences
Jochen D Schipke, Malte Kelm, Klaus Siegmund, Thomas Muth, Burkhard Sievers, Stephan Steiner
There is a complex interaction between the heart and the lungs. We report on a healthy female who performs breath hold diving at a high, international level. In order to optimize pressure equalization during diving and to increase oxygen available, apneists employed a special breathing maneuver, so called "lung packing". Based on cardiac MRI we could demonstrate impressive effects of this maneuver on left ventricular geometry and hemodynamics. Beyond the fact, that our findings support the concept of pulmonary -cardiac interrelationship, it should be emphasized, that the reported, extreme breathing maneuver could have detrimental consequences due to reduction of stroke volume and cardiac output...
2015: Respiratory Medicine Case Reports
Jenny Carolina Rodríguez-Villalobos, Thierry Martin Work, Luis Eduardo Calderon-Aguilera, Héctor Reyes-Bonilla, Luis Hernández
Coral reefs rival rainforest in biodiversity, but are declining in part because of disease. Tissue loss lesions, a manifestation of disease, are present in dominant Pocillopora along the Pacific coast of Mexico. We characterized tissue loss in 7 species of Pocillopora from 9 locations (44 sites) spanning southern to northern Mexico. Corals were identified to species, and tissue loss lesions were photographed and classified as those explainable by predation and those that were unexplained. A focal predation study was done concurrently at 3 locations to confirm origin of explained lesions...
October 16, 2015: Diseases of Aquatic Organisms
M R Timofeeva, S A Lukina
The study presents a comprehensive of the metabolism and the fractional composition of li- pids surfactant, water balance, hemostatic activity of the lungs in neyrodegeneration substantia nigra of the brain induced by stereotaxic microinjection of 6--hydroxydopamine and systemic administration of haloperidol. It is shown that a breach of dopaminergic neurotransmission leads to deterioration of surface-active properties of the alveolar lining of the complex against a decrea- se of phospholipids, cholesterol, phosphatidylcholine and lysophospholipids enhance the pulmo- nary surfactant in the activation of phospholipase hydrolysis and lipid peroxidation...
June 2015: Rossiĭskii Fiziologicheskiĭ Zhurnal Imeni I.M. Sechenova
Afroditi K Boutou, Zaid Zoumot, Arjun Nair, Claire Davey, David M Hansell, Athanasios Jamurtas, Michael I Polkey, Nicholas S Hopkinson
Dynamic hyperinflation (DH) is a pathophysiologic hallmark of Chronic Obstructive Pulmonary Disease (COPD). The aim of this study was to investigate the impact of emphysema distribution on DH during a maximal cardiopulmonary exercise test (CPET) in patients with severe COPD. This was a retrospective analysis of prospectively collected data among severe COPD patients who underwent thoracic high-resolution computed tomography, full lung function measurements and maximal CPET with inspiratory manouvers as assessment for a lung volume reduction procedure...
2015: COPD
Antonella Leone, Raffaella Marina Lecci, Miriana Durante, Federica Meli, Stefano Piraino
Jellyfish are recorded with increasing frequency and magnitude in many coastal areas and several species display biological features comparable to the most popular Asiatic edible jellyfish. The biochemical and antioxidant properties of wild gelatinous biomasses, in terms of nutritional and nutraceutical values, are still largely unexplored. In this paper, three of the most abundant and commonly recorded jellyfish species (Aurelia sp.1, Cotylorhiza tuberculata and Rhizostoma pulmo) in the Mediterranean Sea were subject to investigation...
August 2015: Marine Drugs
Marc Righini, Grégoire Le Gal
The diagnosis of venous thromboembolism relies on the sequential use of diagnostic tests, in validated diagnostic algorithms, based on the prior assessment of the pretest probability. Main diagnostic tests are D-Dimer and lower limb vein compression ultrasonography for deep vein thrombosis; and D-Dimer, computed tomography pulmonary angiography or lung ventilation perfusion scan for pulmonary embolism. These diagnostic strategies allow avoiding the use of the historical reference tests for venous thromboembolism, i...
February 2015: La Revue du Praticien
Elżbieta Katarzyna Biernacka, Ewa Piotrowicz, Aneta Fronczak, Magdalena Mazgaj, Marcin Demkow, Witold Rużyłło, Mateusz Śpiewak, Mirosław Kowalski, Ryszard Piotrowicz, Krzysztof Weroński, Piotr Hoffman
BACKGROUND: The aim of the study was to evaluate the role of cardiopulmonary exercise testing (CPET) parameters in assessing exercise capacity improvement after percutaneous pulmonary valve implantation (PPVI). Additionally, it aimed to determine if there are any baseline characteristics influencing that change. METHODS AND RESULTS: The study comprised 32 patients (mean age 26 ± 9); 53% males; diagnosis: tetralogy of Fallot (n = 18), pulmonary atresia (n = 6), Ross procedure (n = 4), other (transposition of great arteries, pulmonary stenosis, double outlet right ventricle, common arterial trunk type II--n = 4) who underwent successful PPVI due to right ventricular out-flow tract dysfunction (predominant pulmonary regurgitation--n = 17, predominant pulmonary stenosis--n = 15)...
2015: Cardiology Journal
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