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https://www.readbyqxmd.com/read/28741862/in-vivo-comparison-of-jellyfish-and-bovine-collagen-sponges-as-prototype-medical-devices
#1
Jonathan P Widdowson, Alex J Picton, Valerie Vince, Chris J Wright, Andrew Mearns-Spragg
Jellyfish have emerged as a source of next generation collagen that is an attractive alternative to existing sources, such as bovine and porcine, due to a plentiful supply and providing a safer source through lack of bovine spongiform encephalopathy (BSE) transmission risk and potential viral vectors, both of which could be transmitted to humans. Here we compare collagen implantable sponges derived for the first time from the Rhizostoma pulmo jellyfish. A further novelty for the research was that there was a comparison for sponges that were either uncrosslinked or crosslinked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), and an assessment on how this affected resorption, as well as their biocompatibility compared to bovine type I collagen sponges...
July 25, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28601877/-successful-treatment-of-neonatal-respiratory-transitional-disorder-with-pulmo-vivianit-comp-in-2-cases
#2
Benedikt M Huber, Dirk Bassler
BACKGROUND: Disorders of the respiratory transition at birth are major reasons for neonates being admitted to intensive care units and separated from their mothers. This has potential long-lasting consequences for the mother-infant interaction as well as the long-term development of the child. There is an urgent need for effective preventive and therapeutic measures for this frequent disorder. CASE REPORT: We report the cases of 2 newborn infants with respiratory transitional disorder treated off-label with the anthroposophic medicament Pulmo/Vivianit comp...
2017: Complementary Medicine Research
https://www.readbyqxmd.com/read/28599394/pulmo-uterinus-a-history-of-ideas-on-fetal-respiration
#3
REVIEW
Michael Obladen
Theories about fetal respiration began in antiquity. Aristotle characterized pneuma as warm air, but also as the enabler of vital functions and instrument of the soul. In Galen's system of physiology, the vital spirit was carried by the umbilical arteries, the nutrients by the umbilical vein from the placenta to the fetus. In 1569 Aranzio postulated that the maternal and fetal vasculatures are distinct. From 1670 to 1690, a century before the discovery of oxygen, researchers understood that during respiration some form of exchange with the air must occur, naming the substance biolychnium, phlogiston, sal-nitro, or nitro-aerial particles...
May 24, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28538775/a-murine-model-of-elastase-and-cigarette-smoke-induced-emphysema
#4
Rubia Rodrigues, Clarice Rosa Olivo, Juliana Dias Lourenço, Alyne Riane, Daniela Aparecida de Brito Cervilha, Juliana Tiyaki Ito, Milton de Arruda Martins, Fernanda Degobbi Tenório Quirino Dos Santos Lopes
Objective: To describe a murine model of emphysema induced by a combination of exposure to cigarette smoke (CS) and instillation of porcine pancreatic elastase (PPE). Methods: A total of 38 C57BL/6 mice were randomly divided into four groups: control (one intranasal instillation of 0.9% saline solution); PPE (two intranasal instillations of PPE); CS (CS exposure for 60 days); and CS + PPE (two intranasal instillations of PPE + CS exposure for 60 days). At the end of the experimental protocol, all animals were anesthetized and tracheostomized for calculation of respiratory mechanics parameters...
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28396155/partial-purification-and-identification-of-a-metalloproteinase-with-anticoagulant-activity-from-rhizostoma-pulmo-barrel-jellyfish
#5
Akriti Rastogi, Angshuman Sarkar, Dibakar Chakrabarty
Rhizostoma pulmo (Barrel Jellyfish) is one of the commonly found jellyfishes on the South-Goan coast of India. Here we present characterization of R. pulmo tentacle extract. The tentacle extracts were found to be capable of affecting the hemostatic system at three different levels, as it exhibited fibrinogenolysis, fibrinolysis and inhibition of ADP induced platelet aggregation. It preferentially cleaved the Aα chain of fibrinogen, followed by the Bβ chain and the γ chain. The tentacle extract also showed significant hemolytic activity against human RBCs and strong proteolytic activity for substrates like (azo) casein and gelatin...
June 15, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28380189/extracorporeal-respiratory-support-in-adult-patients
#6
Thiago Gomes Romano, Pedro Vitale Mendes, Marcelo Park, Eduardo Leite Vieira Costa
In patients with severe respiratory failure, either hypoxemic or hypercapnic, life support with mechanical ventilation alone can be insufficient to meet their needs, especially if one tries to avoid ventilator settings that can cause injury to the lungs. In those patients, extracorporeal membrane oxygenation (ECMO), which is also very effective in removing carbon dioxide from the blood, can provide life support, allowing the application of protective lung ventilation. In this review article, we aim to explore some of the most relevant aspects of using ECMO for respiratory support...
January 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28235909/crying-a-river-how-much-salt-laden-jelly-can-a-leatherback-turtle-really-eat
#7
John Davenport
Leatherback turtles (Dermochelys coriacea) are capital breeders that accumulate blubber (33 kJ g(-1) wet mass) by hyperphagia on a gelatinous diet at high latitudes; they breed in the tropics. A jellyfish diet is energy poor (0.1-0.2 kJ g(-1) wet mass) so leatherbacks must ingest large quantities. Two published estimates of feeding rate [50% body mass day(-1) (on Rhizostoma pulmo) and 73% body mass day(-1) (on Cyanea capillata)] have been criticised as too high. Jellyfish have high salt and water contents that must be removed to access organic material and energy...
May 1, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28000727/evidence-of-cnidarians-sensitivity-to-sound-after-exposure-to-low-frequency-noise-underwater-sources
#8
Marta Solé, Marc Lenoir, José Manuel Fontuño, Mercè Durfort, Mike van der Schaar, Michel André
Jellyfishes represent a group of species that play an important role in oceans, particularly as a food source for different taxa and as a predator of fish larvae and planktonic prey. The massive introduction of artificial sound sources in the oceans has become a concern to science and society. While we are only beginning to understand that non-hearing specialists like cephalopods can be affected by anthropogenic noises and regulation is underway to measure European water noise levels, we still don't know yet if the impact of sound may be extended to other lower level taxa of the food web...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27759836/advances-in-lung-ultrasound
#9
Miguel José Francisco, Antonio Rahal, Fabio Augusto Cardillo Vieira, Paulo Savoia Dias da Silva, Marcelo Buarque de Gusmão Funari
Ultrasound examination of the chest has advanced in recent decades. This imaging modality is currently used to diagnose several pathological conditions and provides qualitative and quantitative information. Acoustic barriers represented by the aerated lungs and the bony framework of the chest generate well-described sonographic artifacts that can be used as diagnostic aids. The normal pleural line and A, B, C, E and Z lines (also known as false B lines) are artifacts with specific characteristics. Lung consolidation and pneumothorax sonographic patterns are also well established...
July 2016: Einstein
https://www.readbyqxmd.com/read/27683774/evaluation-of-the-thoracoabdominal-mobility-of-obese-subjects-in-pre-bariatric-surgery
#10
Ana Paula Limongi Richardelli Veloso, Karla Garcez Cusmanich
Background: Obesity can affect the thorax, diaphragm, and alterations in respiratory function even if the lungs are within normality. The respiratory compliance is very reduced by the increase in fat mass. Aim: To evaluate the effect of the physical therapeutic respiratory exercises on the thoracoabdominal mobility of obese individuals in pre-bariatric surgery. Methods: Cross-sectional and descriptive study, which used the cirtometry (axillary, xiphoid and abdominal) to evaluate the mobility of 74 individuals, 27 men and 47 women, in pre-bariatric surgery, assisted by the team EMAD, after eight weeks of physiotherapy, following a protocol of exercises, reevaluating and compared the measures pre and post intervention...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27598602/endogenous-erythropoietin-level-and-effects-of-exogenous-erythropoietin-in-a-rat-model-of-blunt-chest-trauma-induced-pulmonary-contusion
#11
Vedat Bakan, Ergül Belge Kurutaş, Harun Çıralık, Mustafa Gül, Ahmet Çelik
BACKGROUND: The present objective was to investigate endogen erythropoietin (EPO) level and relationship to oxidative stress within the first 24 hours of blunt chest trauma-induced pulmo-nary contusion (PCn) in a rat model. METHODS: Thirty-five rats were divided into 3 groups. In the baseline control group (BC, n=7), rats were uninjured and untreated. In the positive control group (PC, n=21) rats were injured but untreated. In the EPO-24 group (n=7), rats were injured and a single dose of intra-peritoneal EPO (5000 IU/kg) was administered immediately after lung injury...
July 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/27376999/patterns-of-trace-element-bioaccumulation-in-jellyfish-rhizostoma-pulmo-cnidaria-scyphozoa-in-a-mediterranean-coastal-lagoon-from-se-spain
#12
Ana Muñoz-Vera, Jose Matías Peñas Castejón, Gregorio García
The effects of an abandoned mining area, exploited for centuries in the mining district of Cartagena-La Union, result in a continuous supply of heavy metals into the Mar Menor coastal lagoon after rain episodes. As a consequence, concentration of trace elements in water column and sediments of this ecosystem is usually higher than in other areas. For monitoring ecosystem health, this study assessed the ability of Rhizostoma pulmo to bioaccumulate trace elements. A total of 57 individuals were sampled at eight different sampling stations during the summer of 2012...
September 15, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27343583/enhancement-of-aptamer-immobilization-using-egg-shell-derived-nano-sized-spherical-hydroxyapatite-for-thrombin-detection-in-neuroclinic
#13
Burak Derkus, Yavuz Emre Arslan, Kaan C Emregul, Emel Emregul
In the present study, we describe the sonochemical isolation of nano-sized spherical hydroxyapatite (nHA) from egg shell and application towards thrombin aptasensing. In addition to the sonochemical method, two conventional methods present in literature were carried out to perform a comparative study. Various analysis methods including Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), Energy-Dispersive Analysis of X-Rays (EDAX), and Thermal Gravimetric Analysis (TGA) have been applied for the characterization of nHA and its nanocomposite with marine-derived collagen isolated from Rhizostoma pulmo jellyfish...
September 1, 2016: Talanta
https://www.readbyqxmd.com/read/27147270/toxicity-of-mediterranean-scyphomedusae-an-overview
#14
REVIEW
Paola Del Negro, Ciriaco Saul, Cataletto Bruno, Delogu G Maria, Kokelj Franco
Following in-depth analysis and examination, jellyfish toxins have been found to consist of a mixture of proteins, carbohydrates, and other non-proteinaceous components. What remains to be clarified is the specific chemical nature of jellyfish toxins due to their heat lability. This paper reviews current knowledge of the toxic properties of the most common Mediterranean scyphozoans (A. aurita, C. hysoscella, C. tuberculata, P. noctiluca, R. pulmo) and the activity of their venom.
2016: Central Nervous System Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/26965421/management-of-deep-vein-thrombosis-and-pulmonary-embolism-venous-thromboembolism-during-pregnancy
#15
Wakako Fukuda, Mari Chiyoya, Satoshi Taniguchi, Kazuyuki Daitoku, Ikuo Fukuda
PURPOSE: The risk of venous thromboembolism (VTE) is high during pregnancy. Although most patients with VTE are safely treated via medications, the optimal treatment for massive pulmonary embolism remains controversial. To evaluate the safety and efficacy of VTE management during pregnancy, we report our single center experience of treating VTE in pregnant women. METHODS: Case records were retrospectively reviewed from seven patients who underwent treatment for venous thromboembolism between 2002 and 2014...
June 2016: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26929612/depression-body-mass-index-and-chronic-obstructive-pulmonary-disease-a-holistic-approach
#16
COMPARATIVE STUDY
Giuseppe Catalfo, Luciana Crea, Tiziana Lo Castro, Francesca Magnano San Lio, Giuseppe Minutolo, Gherardo Siscaro, Noemi Vaccino, Nunzio Crimi, Eugenio Aguglia
BACKGROUND: Several clinical studies suggest common underlying pathogenetic mechanisms of COPD and depressive/anxiety disorders. We aim to evaluate psychopathological and physical effects of aerobic exercise, proposed in the context of pulmonary rehabilitation, in a sample of COPD patients, through the correlation of some psychopathological variables and physical/pneumological parameters. METHODS: Fifty-two consecutive subjects were enrolled. At baseline, the sample was divided into two subgroups consisting of 38 depression-positive and 14 depression-negative subjects according to the Hamilton Depression Rating Scale (HAM-D)...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/26865696/a-hand2-loss-of-function-mutation-causes-familial-ventricular-septal-defect-and-pulmonary-stenosis
#17
Yu-Min Sun, Jun Wang, Xing-Biao Qiu, Fang Yuan, Ruo-Gu Li, Ying-Jia Xu, Xin-Kai Qu, Hong-Yu Shi, Xu-Min Hou, Ri-Tai Huang, Song Xue, Yi-Qing Yang
Congenital heart disease (CHD) is the most common developmental abnormality, and is the leading noninfectious cause of mortality in neonates. Increasing evidence demonstrates that genetic defects play an important role in the pathogenesis of CHD. However, CHD exhibits substantial heterogeneity, and the genetic determinants for CHD remain unknown in the overwhelming majority of cases. In the current study, the coding exons and flanking introns of the HAND2 gene, which encodes a basic helix-loop-helix transcription factor essential for normal cardiovascular development, were sequenced in 192 unrelated patients with CHD, and a novel heterozygous mutation, p...
2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/26857907/catheter-ablation-of-nonparoxysmal-atrial-fibrillation-using-electrophysiologically-guided-substrate-modification-during-sinus-rhythm-after-pulmonary-vein-isolation
#18
COMPARATIVE STUDY
Gang Yang, Bing Yang, Youquan Wei, Fengxiang Zhang, Weizhu Ju, Hongwu Chen, Mingfang Li, Kai Gu, Yazhou Lin, Benqi Wang, Kejiang Cao, Pipin Kojodjojo, Minglong Chen
BACKGROUND: The high incidence of postprocedural atrial tachycardia reduces the absolute arrhythmia-free success rate of extensive ablation strategies to treat nonparoxysmal atrial fibrillation (NPAF). We hypothesized that a strategy of targeting low-voltage zones and sites with abnormal electrograms during sinus rhythm (SR-AEs) in the left atrium after circumferential pulmonary vein isolation and cavotricuspid isthmus ablation in patients with NPAF is superior. METHODS AND RESULTS: A total of 86 consecutive patients with NPAF were enrolled in study group...
February 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/26848601/the-critical-role-of-pulmonary-arterial-compliance-in-pulmonary-hypertension
#19
REVIEW
Thenappan Thenappan, Kurt W Prins, Marc R Pritzker, John Scandurra, Karl Volmers, E Kenneth Weir
The normal pulmonary circulation is a low-pressure, high-compliance system. Pulmonary arterial compliance decreases in the presence of pulmonary hypertension because of increased extracellular matrix/collagen deposition in the pulmonary arteries. Loss of pulmonary arterial compliance has been consistently shown to be a predictor of increased mortality in patients with pulmonary hypertension, even more so than pulmonary vascular resistance in some studies. Decreased pulmonary arterial compliance causes premature reflection of waves from the distal pulmonary vasculature, leading to increased pulsatile right ventricular afterload and eventually right ventricular failure...
February 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/26846692/impact-of-pulmonary-disease-on-patient-reported-outcomes-and-patient-performed-functional-testing-in-systemic-lupus-erythematosus
#20
L Fidler, K J Keen, Z Touma, S Mittoo
OBJECTIVES: This study examines the effect of pulmonary disease on patient-reported outcomes (PROs) and patient-performed outcome (PPO) in systemic lupus erythematosus (SLE) patients at a single tertiary referral center. METHODS: Pulmonary function tests (PFTs), chest imaging, SLE-related damage, and disease activity were examined in 110 SLE patients. Presence was noted of abnormal PFTs, pleural disease, pulmonary hypertension (PH), pulmonary infarction, interstitial lung disease (ILD), and shrinking lung syndrome (SLS)...
August 2016: Lupus
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