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Shear wave elastography carotid

Erik Widman, Elira Maksuti, Carolina Amador, Matthew W Urban, Kenneth Caidahl, Matilda Larsson
Five small porcine aortas were used as a human carotid artery model, and their stiffness was estimated using shear wave elastography (SWE) in the arterial wall and a stiffened artery region mimicking a stiff plaque. To optimize the SWE settings, shear wave bandwidth was measured with respect to acoustic radiation force push length and number of compounded angles used for motion detection with plane wave imaging. The mean arterial wall and simulated plaque shear moduli varied from 41 ± 5 to 97 ± 10 kPa and from 86 ± 13 to 174 ± 35 kPa, respectively, over the pressure range 20-120 mmHg...
October 2016: Ultrasound in Medicine & Biology
Erika Iwamoto, Megumi Minakami, Ryohei Nagaoka, Toru Neki, Keigo Taniguchi, Masaki Katayose
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Chris L de Korte, Stein Fekkes, Aart J Nederveen, Rashindra Manniesing, Hendrik Rik H G Hansen
Cardiovascular disease (CVD) is a leading cause of death and is in the majority of cases due to the formation of atherosclerotic plaques in arteries. Initially, thickening of the inner layer of the arterial wall occurs. Continuation of this process leads to plaque formation. The risk of a plaque to rupture and thus to induce an ischemic event is directly related to its composition. Consequently, characterization of the plaque composition and its proneness to rupture are of crucial importance for risk assessment and treatment strategies...
October 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Zhaojun Li, Lianfang Du, Feng Wang, Xianghong Luo
AIM: Arterial wall elasticity including the circumferential and longitudinal modulus is a measure of sub-clinical cardiovascular disease; the circumferential modulus is increased in acute ischemic stroke (AIS). There are still no reports of non-invasive measurement of longitudinal elastic modulus of arterial wall and its prospect of clinical application. In this study, the longitudinal elastic modulus of the arterial wall was assessed using real-time shear wave elastography in patients with AIS...
June 2016: Medical Ultrasonography
F Ozkan, D Ozel, B D Ozel
No abstract text is available yet for this article.
February 2016: Ultraschall in der Medizin
Steven Huntzicker, Rohit Nayak, Marvin M Doyley
Quantitative sparse array vascular elastography visualizes the shear modulus distribution within vascular tissues, information that clinicans could use to reduce the number of strokes each year. However, the low transmit power sparse array (SA) imaging could hamper the clinical usefulness of the resulting elastograms. In this study, we evaluated the performance of modulus elastograms recovered from simulated and physical vessel phantoms with varying attenuation coefficients (0.6, 1.5, and [Formula: see text]) and modulus contrasts ([Formula: see text], [Formula: see text], and [Formula: see text]) using SA imaging relative to those obtained with conventional linear array (CLA) and plane-wave (PW) imaging techniques...
July 2014: Journal of Medical Imaging
J W Garrard, P Ummur, S Nduwayo, B Kanber, T C Hartshorne, K P West, D Moore, T G Robinson, K V Ramnarine
PURPOSE: There is a need to develop methods that reliably quantify characteristics associated with vulnerable carotid plaque. Greyscale median (GSM) and shear wave elastography (SWE) are two techniques that may improve individual plaque risk stratification. SWE, which quantifies Young's Modulus (YM) to estimate tissue stiffness, has been researched in the liver, breast, thyroid and prostate, but its use in carotid plaques is novel. MATERIALS AND METHODS: The aim of this study was to quantify YM and GSM of plaques and compare to histology...
August 2015: Ultraschall in der Medizin
E Widman, E Maksuti, D Larsson, M W Urban, A Bjällmark, M Larsson
Determining plaque vulnerability is critical when selecting the most suitable treatment for patients with atherosclerotic plaque. Currently, clinical non-invasive ultrasound-based methods for plaque characterization are limited to visual assessment of plaque morphology and new quantitative methods are needed. In this study, shear wave elastography (SWE) was used to characterize hard and soft plaque mimicking inclusions in six common carotid artery phantoms by using phase velocity analysis in static and dynamic environments...
April 21, 2015: Physics in Medicine and Biology
Kumar V Ramnarine, James W Garrard, Baris Kanber, Sarah Nduwayo, Timothy C Hartshorne, Thompson G Robinson
BACKGROUND: Shear Wave Elastography (SWE) imaging is a novel ultrasound technique for quantifying tissue elasticity. Studies have demonstrated that SWE is able to differentiate between diseased and normal tissue in a wide range clinical applications. However its applicability to atherosclerotic carotid disease has not been established. The aim of this study was to assess the feasibility and potential clinical benefit of using SWE imaging for the assessment of carotid plaques. METHODS: Eighty-one patients (mean age 76 years, 51 male) underwent greyscale and SWE imaging...
2014: Cardiovascular Ultrasound
Marjan Razani, Timothy W H Luk, Adrian Mariampillai, Peter Siegler, Tim-Rasmus Kiehl, Michael C Kolios, Victor X D Yang
In this work, we explored the potential of measuring shear wave propagation using optical coherence elastography (OCE) in an inhomogeneous phantom and carotid artery samples based on a swept-source optical coherence tomography (OCT) system. Shear waves were generated using a piezoelectric transducer transmitting sine-wave bursts of 400 μs duration, applying acoustic radiation force (ARF) to inhomogeneous phantoms and carotid artery samples, synchronized with a swept-source OCT (SS-OCT) imaging system. The phantoms were composed of gelatin and titanium dioxide whereas the carotid artery samples were embedded in gel...
March 1, 2014: Biomedical Optics Express
Massimiliano Andrioli, Luca Persani
Thyroid nodules are very common with malignancies accounting for about 5 %. Fine-needle biopsy is the most accurate test for thyroid cancer diagnosis. Elastography, a new technology directly evaluating the elastic property of the tissue, has been recently added to the diagnostic armamentarium of the endocrinologists as noninvasive predictor of thyroid malignancy. In this paper, we critically reviewed characteristics and applications of elastographic methods in thyroid gland. Elastographic techniques can be classified on the basis of the following: source-of-tissue compression (free-hand, carotid vibration, ultrasound pulses), processing time (real-time, off-line), stiffness expression (qualitative, semi-quantitative, or quantitative)...
August 2014: Endocrine
Kumar V Ramnarine, James W Garrard, Katie Dexter, Sarah Nduwayo, Ronney B Panerai, Thompson G Robinson
This study assessed inter- and intra-observer reproducibility of shear wave elastography (SWE) measurements in vessel phantoms simulating soft and hard carotid plaque under steady and pulsatile flow conditions. Supersonic SWE was used to acquire cine-loop data and quantify Young's modulus in cryogel vessel phantoms. Data were acquired by two observers, each performing three repeat measurements. Mean Young's modulus was quantified within 2-mm regions of interest averaged across five frames and, depending on vessel model and observer, ranged from 28 to 240 kPa...
January 2014: Ultrasound in Medicine & Biology
J W Garrard, K Ramnarine
No abstract text is available yet for this article.
February 2014: Ultraschall in der Medizin
H Monpeyssen, J Tramalloni, S Poirée, O Hélénon, J-M Correas
Thyroid nodules are very common, while thyroid cancer is rare and has a very good prognosis. Thyroid nodule ultrasound characterization performed by experienced clinicians allows the selection of the tumours to be punctured and guiding fine needle aspiration (FNA). FNA provide cytology information able to differentiate benign tumours from cancer in approximately 80% of cases. However, it remains difficult to identify thyroid cancers with ultrasound imaging, as demonstrated by the very low rate of cancers detected in all of the carried out FNA (approximately 5%)...
May 2013: Diagnostic and Interventional Imaging
Sanghamithra Korukonda, Rohit Nayak, Nancy Carson, Giovanni Schifitto, Vikram Dogra, Marvin M Doyley
Stroke may occur when an atherosclerotic plaque ruptures in the carotid artery. Noninvasive vascular elastography (NIVE) visualizes the strain distribution within the carotid artery, which is related to its mechanical properties that govern plaque rupture. Strain elastograms obtained from the transverse plane of the carotid artery are difficult to interpret, because strain is estimated in Cartesian coordinates. Sparsearray (SA) elastography overcomes this problem by transforming shear and normal strain to polar coordinates...
February 2013: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
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