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https://www.readbyqxmd.com/read/18387605/the-action-of-extracellular-nad-in-the-liver-of-healthy-and-tumor-bearing-rats-model-analysis-of-the-tumor-induced-modified-response
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Anacharis Babeto de Sá-Nakanishi, Fabrício Bracht, Nair Seiko Yamamoto, Fábio Padilha, Ana Maria Kelmer-Bracht, Adelar Bracht
The chronic inflammatory state induced by cancer is expected to affect the actions of extracellular NAD(+) in the liver because these are largely mediated by eicosanoids. Under this assumption the present work was planned to investigate the influence of the Walker-256 tumor on the action of extracellular NAD(+) on metabolism and hemodynamics in the perfused rat liver. The experiments were done with livers from healthy and tumor-bearing rats with measurements of gluconeogenesis from lactate, pyruvate production, oxygen consumption and portal pressure...
June 2008: Experimental and Molecular Pathology
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