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https://www.readbyqxmd.com/read/28606470/mechanistic-evaluation-of-gastroprotective-effects-of-kangfuxin-on-ethanol-induced-gastric-ulcer-in-mice
#1
Yongmei Shen, Jia Sun, Chao Niu, Dongdong Yu, Zhiwei Chen, Weitao Cong, Funeng Geng
This study was designed to evaluate the gastroprotective effect of Kangfuxin (KFX), a Chinese patent medicine constituent isolated from American cockroach, on ethanol-induced gastric ulcer in mice and to elucidate the potential mechanisms of the effect involved. According to the results, mice treated with alcohol appeared obvious gastric mucosal injury, while treatment with Cimetidine (a positive control) and KFX significantly relieved the damage, along with decreased oxidative stress and apoptosis indexes...
June 9, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28573241/mechanisms-underlying-action-of-xinmailong-injection-a-traditional-chinese-medicine-in-cardiac-function-improvement
#2
Zhengtao Li, Sujuan Li, Lin Hu, Fang Li, Alex Chun Cheung, Weizai Shao, Yuling Que, George Pek-Heng Leung, Cui Yang
BACKGROUND: As a bioactive composite extracted from American cockroach, Xinmailong injection (XML) is used for the treatment of congestive heart failure (CHF) in China. Clinical data has provided evidence that XML has positive inotropic properties. The objective of this study was to assess the mechanisms involved in the therapeutical effect of XML on CHF. MATERIALS AND METHODS: The effects of XML on the cardiac function in isolated rat heart were measured. A Ca(2+) imaging technology was used in rat cardiomyocytes (H9c2 cells) to reveal the role of XML on Ca(2+) channels...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28548451/molecular-and-functional-characterization-of-the-american-cockroach-periplaneta-americana-rab5-the-first-exopterygotan-low-molecular-weight-ovarian-gtpase-during-oogenesis
#3
Mohamed Elmogy, Amr A Mohamed, Muhammad Tufail, Tomohide Uno, Makio Takeda
The small Rab GTPases are key regulators of membrane vesicle trafficking. Ovaries of Periplaneta americana (Linnaeus) (Blattodea: Blattidae) have small molecular weight GTP/ATP-binding proteins during early and late vitellogenic periods of oogenesis. However, the identification and characterization of the detected proteins have not been yet reported. Herein, we cloned a cDNA encoding Rab5 from the American cockroach, P. americana, ovaries (PamRab5). It comprises 796 bp, encoding a protein of 213 amino acid residues with a predicted molecular weight of 23...
May 26, 2017: Insect Science
https://www.readbyqxmd.com/read/28506564/contamination-of-cockroaches-insecta-blattaria-to-medically-fungi-a-systematic-review-and-meta-analysis
#4
REVIEW
H Nasirian
INTRODUCTION: Fungal infections have emerged worldwide. Cockroaches have been proved vectors of medically fungi. METHODS: A systematic meta-analysis review about cockroach fungal contamination was investigated. Relevant topics were collected between January 2016 and January 2017. After a preliminary review among 392 collected papers, 156 were selected to become part of the detailed systematic meta-analysis review. RESULTS: Cockroaches contaminated to 38 fungi species belonging to 19 families and 12 orders...
May 11, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28475112/insect-active-toxins-with-promiscuous-pharmacology-from-the-african-theraphosid-spider-monocentropus-balfouri
#5
Jennifer J Smith, Volker Herzig, Maria P Ikonomopoulou, Sławomir Dziemborowicz, Frank Bosmans, Graham M Nicholson, Glenn F King
Many chemical insecticides are becoming less efficacious due to rising resistance in pest species, which has created much interest in the development of new, eco-friendly bioinsecticides. Since insects are the primary prey of most spiders, their venoms are a rich source of insect-active peptides that can be used as leads for new bioinsecticides or as tools to study molecular receptors that are insecticidal targets. In the present study, we isolated two insecticidal peptides, µ/ω-TRTX-Mb1a and -Mb1b, from venom of the African tarantula Monocentropus balfouri...
May 5, 2017: Toxins
https://www.readbyqxmd.com/read/28433752/serotonergic-transmission-and-gap-junctional-coupling-in-proventricular-muscle-cells-in-the-american-cockroach-periplaneta-americana
#6
Ryoichi Yoshimura, Taeko Suetsugu, Yasuhisa Endo
The visceral muscle tissues of insects consist of striated muscle cells. The mechanisms responsible for delivering signals to the contractile muscles in the insect digestive tract remain unclear. We found that serotonergic nerves innervate the hemocoel surfaces of foregut and midgut muscles in the American cockroach. Electron microscopy of the neuromuscular junctions in the proventriculus (gizzard) revealed typical synaptic structures, the accumulation of large core/cored vesicles (neuropeptides) and small clear vesicle (neurotransmitter) at presynapses, and synaptic clefts...
April 19, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28429621/the-distribution-and-movement-of-american-cockroaches-in-urban-niches-of-new-orleans
#7
John C Carlson, Felicia A Rabito, Derek Werthmann, Mark Fox
American cockroaches are an important source of household allergens in tropical and semitropical climates. To determine which outdoor niches produce American cockroaches, traps were placed at 40 homes in New Orleans to collect nymphs. Nymphs were collected from the sewers, yards, and within the homes themselves. To compare sewers and yards as sources of cockroaches entering homes, adult cockroaches were collected, marked, and released into yards and sewers. No sewer-released cockroaches were collected in homes...
April 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28426402/molecular-identification-of-thelandros-scleratus-and-thelastoma-icemi-nematoda-oxyruida-using-mitochondrial-cox-1-sequences
#8
Anshu Chaudhary, Garima Kansal, Neetu Singh, Kumari Shobhna, Manu Verma, Hridaya S Singh
Two species of parasitic nematodes collected from the intestine of Brook's House Gecko, Hemidactylus brooki and American cockroach, Periplaneta americana L. The parasites were identified as Thelandros scleratus and Thelastoma icemi by PCR amplification method. Subsequently, sequence analysis of mt cox1 (504 and 540 bp) for T. scleratus and T. icemi respectively revealed that these sequences showed maximum similarity of 90% (in case of T. scleratus), 77% (in case of T. icemi), to nematode sequences available on GenBank...
June 1, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/28404730/not-flying-blind-a-comparative-study-of-photoreceptor-function-in-flying-and-non-flying-cockroaches
#9
Roman V Frolov, Atsuko Matsushita, Kentaro Arikawa
Flying is often associated with superior visual performance since good vision is crucial for detection and implementation of rapid visually-guided aerial movements. To understand the evolution of insect visual systems it is therefore important to compare phylogenetically related species with different investments into flight capability. Here, we describe and compare morphological and electrophysiological properties of photoreceptors from the habitually flying green cockroach Panchlora nivea, and the American cockroach Periplaneta americana, which flies only at high ambient temperatures...
April 12, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28331632/group-housed-females-promote-production-of-asexual-ootheca-in-american-cockroaches
#10
Ko Katoh, Masazumi Iwasaki, Shouhei Hosono, Atsushi Yoritsune, Masanori Ochiai, Makoto Mizunami, Hiroshi Nishino
BACKGROUND: Facultative parthenogenesis, seen in many animal phyla, is a reproductive strategy in which females are able to generate offspring when mating partners are unavailable. In some subsocial and eusocial insects, parthenogenesis is often more prevalent than sexual reproduction. However, little is known about how social cooperation is linked to the promotion of parthenogenesis. The domiciliary cockroach Periplaneta americana is well-suited to addressing this issue as this species belongs to the superfamily Blattoidea, which diverged into eusocial termites and shows facultative parthenogenesis...
2017: Zoological Letters
https://www.readbyqxmd.com/read/28317204/cockroach-allergen-serine-proteinases-isolation-sequencing-and-signalling-via-proteinase-activated-receptor-2
#11
D J Polley, K Mihara, R Ramachandran, H Vliagoftis, B Renaux, M Saifeddine, M O Daines, S Boitano, M D Hollenberg
BACKGROUND: Allergy to the German cockroach (Blattella germanica) is a significant asthma risk factor for inner-city communities. Cockroach, like other allergens, contains trypsin-like enzyme activity that contributes to allergenicity and airway inflammation by activating proteinase-activated receptors (PARs). To date, the enzymes responsible for the proteolytic activity of German cockroach allergen have not been characterized. OBJECTIVES: We aimed to identify, isolate and characterize the trypsin-like proteinases in German cockroach allergen extracts used for clinical skin tests...
March 20, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28228922/parasitic-gregarine-blattarum-found-infecting-american-cockroaches-periplaneta-americana-in-a-population-in-pulau-pinang-malaysia
#12
Zary Shariman Yahaya, Nik Ahmad Irwan Izzaudin, Ainul Farhana Abdul Razak
A study on the prevalence of a common endoparasite in the wild population of the American cockroach was conducted in Penang Island using a trapping method at several sampling sites on the island. Gregarine blattarum was found in the digestive tract in 5 out of 115, or 4.35%, of the wild American cockroaches, Periplaneta americana, that were sampled. This is the first report in Malaysia of Gregarine blattarum in local American cockroaches.
January 2017: Tropical Life Sciences Research
https://www.readbyqxmd.com/read/28188710/-prevalence-of-sensitization-to-inhalant-allergens-in-the-immunology-department-from-hospital-de-especialidades-pedi%C3%A3-tricas-mar%C3%A3-a-honduras-2016
#13
Victoria Alejandra Gonzales-González, Adolfo Martín Díaz-Flores, Karla Zobeyda Fernández-Zelaya, María Félix Rivera-Reyes
BACKGROUND: Allergic diseases are a public health problem; estimates indicate that between 30% and 40% of the world population is affected by some allergy. Knowing the prevalence of allergen sensitization allows for adequate diagnoses and treatments to be offered. In Honduras there are no studies available in pediatric patients. OBJECTIVE: The purpose of this research was to identify the most common types of sensitization in children and their correlation with the most common allergic diseases in patients on immunotherapy at the Maria Hospital of Pediatric Specialties...
January 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28183995/structure-of-a-eukaryotic-voltage-gated-sodium-channel-at-near-atomic-resolution
#14
Huaizong Shen, Qiang Zhou, Xiaojing Pan, Zhangqiang Li, Jianping Wu, Nieng Yan
Voltage-gated sodium (Nav) channels are responsible for the initiation and propagation of action potentials. They are associated with a variety of channelopathies and are targeted by multiple pharmaceutical drugs and natural toxins. Here, we report the cryo-EM structure of a putative Nav channel from American cockroach (designated NavPaS) at 3.8-Å resolution. The voltage sensing domains (VSDs) of the four repeats exhibit distinct conformations. The entrance to the asymmetric selectivity filter vestibule is guarded by heavily glycosylated and disulfide bond-stabilized extracellular loops...
February 9, 2017: Science
https://www.readbyqxmd.com/read/28173695/the-american-cockroach-peptide-periplanetasin-2-blocks-clostridium-difficile-toxin-a-induced-cell-damage-and-inflammation-in-the-gut
#15
Ji Hong, Peng Zhang, I Na Yoon, Jae Sam Hwang, Jin Ku Kang, Ho Kim
Clostridium difficile, which causes pseudomembranous colitis, releases toxin A and toxin B. These toxins are considered to be the main causative agents for the disease pathogenesis, and their expression is associated with a marked increase of apoptosis in mucosal epithelial cells. Colonic epithelial cells are believed to form a physical barrier between the lumen and the submucosa, and abnormally increased mucosal epithelial cell apoptosis is considered to be an initial step in gut inflammation responses. Therefore, one approach to treating pseudomembranous colitis would be to develop agents that block the mucosal epithelial cell apoptosis caused by toxin A, thus restoring barrier function and curing inflammatory responses in the gut...
April 28, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28081263/molecular-and-functional-characterization-of-three-odorant-binding-protein-from-periplaneta-americana
#16
Zhao-Qun Li, Peng He, Ya-Nan Zhang, Shuang-Lin Dong
The American cockroach, Periplaneta americana, is a vector of many pathogenic organisms associated with human diseases. Olfaction plays a crucial role in guiding cockroach behaviors and contributes to their ability to transmit pathogens. Odorant binding proteins (OBPs), abundant in the insect olfactory sensilla, are important for insect olfaction. In this study, three OBP genes, PameOBP1, 2 and 3, were cloned from P. americana. Sequence alignment and phylogenetic analysis revealed that PameOBP1, 2 and 3 belong to the Minus-C OBP, Classic OBP, and Plus-C OBP subfamilies, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28032104/isolation-and-purification-of-an-antibacterial-protein-from-immune-induced-haemolymph-of-american-cockroach-periplaneta-americana
#17
Hamid Reza Basseri, Amir Dadi-Khoeni, Ronak Bakhtiari, Mandan Abolhassani, Reza Hajihosseini-Baghdadabadi
BACKGROUND: Antimicrobial peptides play a role as effectors substances in the immunity of vertebrate and invertebrate hosts. In the current study, antimicrobial peptide was isolated from the haemolymph of the American cockroach, Periplaneta americana. METHODS: Micrococcus luteus as Gram-positive bacteria and Escherichia coli as Gram-negative bacteria were candidate for injection. Induction was done by injecting both bacteria into the abdominal cavity of two groups of cockroaches separately...
December 2016: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/28028170/influences-of-temperature-and-ootheca-age-on-the-life-history-of-the-cockroach-ootheca-parasitoid-aprostocetus-hagenowii-hymenoptera-eulophidae
#18
Hui-Siang Tee, Chow-Yang Lee
The influences of ootheca age and temperature on the life history of Aprostocetus hagenowii (Ratzeburg) (Hymenoptera: Eulophidae), a gregarious ootheca parasitoid of the American cockroach Periplaneta americana (L.) (Dictyoptera: Blattidae), were evaluated. Oothecae were incubated at 20, 25, and 30 °C to produce oothecae aged 1-60, 1-40, and 1-30 d old, respectively. Fitness traits (development time, percentage emergence, number of progeny, percentage female progeny, and female body size) of A. hagenowii developing in these different-aged oothecae were determined...
February 1, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28007552/the-potential-subunits-involved-in-two-subtypes-of-%C3%AE-bgt-resistant-nachrs-in-cockroach-dorsal-unpaired-median-dum-neurons
#19
Huahua Sun, Yang Liu, Jian Li, Xinzhu Cang, Haibo Bao, Zewen Liu
The american cockroach (Periplaneta americana) dorsal unpaired median (DUM) neurons provide an native tool to analyze the functional and pharmacological properties of ion channels and membrane receptors, such as nicotine acetylcholine receptors (nAChRs). Here the imidacloprid-activated nAChR subtypes were examined in DUM neurons by the patch-clamp technique and the potential subunits involved in important subtypes were analyzed by combining with RNA interference (RNAi) technique. Imidacloprid exerted agonist activities on one subtype in α-Bgt-sensitive nAChRs and another subtype in α-Bgt-resistant nAChRs, in which the α-Bgt-resistant subtype showed much higher sensitivity to imidacloprid than the α-Bgt-sensitive subtype, with the difference close to 200-fold...
February 2017: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27979025/atopy-patch-test-in-children-with-atopic-dermatitis
#20
Nualanong Visitsunthorn, Sunsanee Chatpornvorarux, Punchama Pacharn, Orathai Jirapongsananuruk
BACKGROUND: Atopic dermatitis is frequently associated with food and/or aeroallergen allergy. OBJECTIVE: To evaluate atopy patch tests (APTs) and skin prick tests (SPTs) in children with atopic dermatitis, using allergen extracts from locally lyophilized foods (cow's milk, egg white, egg yolk, wheat, soy, and shrimp), Dermatophagoides pteronyssinus, Dermatophagoides farinae, and American cockroach. METHODS: This study was a prospective, self-controlled study in children with atopic dermatitis...
December 2016: Annals of Allergy, Asthma & Immunology
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