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https://www.readbyqxmd.com/read/28081509/in-silico-prediction-of-toxicity-of-phenols-to-tetrahymena-pyriformis-by-using-genetic-algorithm-and-decision-tree-based-modeling-approach
#1
Fatemeh Abbasitabar, Vahid Zare-Shahabadi
Risk assessment of chemicals is an important issue in environmental protection; however, there is a huge lack of experimental data for a large number of end-points. The experimental determination of toxicity of chemicals involves high costs and time-consuming process. In silico tools such as quantitative structure-toxicity relationship (QSTR) models, which are constructed on the basis of computational molecular descriptors, can predict missing data for toxic end-points for existing or even not yet synthesized chemicals...
January 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28059482/aquatic-toxicity-of-photo-degraded-insensitive-munition-101-imx-101-constituents
#2
Alan J Kennedy, Aimee R Poda, Nicolas L Melby, Lee C Moores, Shinita M Jordan, Kurt A Gust, Anthony J Bednar
Insensitive munitions (IMs) are desirable alternatives to historically used formulations, such as 2,4,6-trinitrotoluene (TNT), due to their "insensitivity" to unintended detonation. The insensitive munition IMX-101 is a mixture of 2,4-dinitroanisole (DNAN), 3-nitro-1,2,4-triazol-5-one (NTO), and nitroguanidine (NQ). Environmental releases of munitions may be from production wastewaters or training; these munitions may be exposed to Ultraviolet light. Therefore, it is useful to understand the relative toxicity of IMX-101 and its constituents both before and after photo-degradation...
January 6, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28029183/temporal-monitoring-of-pfos-accumulation-in-aquatic-biota-downstream-of-historical-aqueous-film-forming-foam-use-areas
#3
Heather A Lanza, Rebecca S Cochran, Joseph F Mudge, Adric D Olson, Brett R Blackwell, Jonathan D Maul, Christopher J Salice, Todd A Anderson
Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic organisms and in regions of exposure to Aqueous Film Forming Foams (AFFFs). Air Force bases historically applied AFFFs in the interest of fire training exercises and have since expressed concern for PFAS contamination in biota from water bodies surrounding former fire training areas. We monitored six PFASs, including perfluorooctane sulfonate (PFOS), in aquatic species from eight bayou locations at Barksdale Air Force Base in Bossier City, Louisiana over the course of one year...
December 28, 2016: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/27999319/exercise-and-beta-glucan-consumption-saccharomyces-cerevisiae-improve-the-metabolic-profile-and-reduce-the-atherogenic-index-in-type-2-diabetic-rats-hfd-stz
#4
Eric Francelino Andrade, Andressa Ribeiro Veiga Lima, Ingrid Edwiges Nunes, Débora Ribeiro Orlando, Paula Novato Gondim, Márcio Gilberto Zangeronimo, Fernando Henrique Ferrari Alves, Luciano José Pereira
Physical activity and the ingestion of dietary fiber are non-drug alternatives commonly used as adjuvants to glycemic control in diabetic individuals. Among these fibers, we can highlight beta-glucans. However, few studies have compared isolated and synergic effects of physical exercise and beta-glucan ingestion, especially in type 2 diabetic rats. Therefore, we evaluated the effects beta-glucan (Saccharomyces cerevisiae) consumption, associated or not to exercise, on metabolic parameters of diabetic Wistar rats...
December 17, 2016: Nutrients
https://www.readbyqxmd.com/read/27992070/exercise-for-haemophilia
#5
REVIEW
Karen Strike, Kathy Mulder, Rojer Michael
BACKGROUND: Haemophilia is a bleeding disorder associated with haemorrhaging into joints and muscles. Exercise is often used to aid recovery after bleeds, and to improve joint function in the presence of arthropathy. OBJECTIVES: Our objective was to systematically review the available evidence on the safety and effectiveness of exercise for people with haemophilia. SEARCH METHODS: We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Coagulopathies Trials Register and electronic databases PubMed, OVID-Embase, and CINAHL...
19, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27989691/aquatic-exercise-training-is-effective-in-maintaining-exercise-performance-in-trained-heart-failure-patients-a-randomised-crossover-pilot-trial
#6
Julie Adsett, Norman Morris, Suzanne Kuys, Rita Hwang, Robert Mullins, Mohsina Khatun, Jennifer Paratz, Alison Mudge
BACKGROUND: Providing flexible models and a variety of exercise options are fundamental to supporting long-term exercise participation for patients with heart failure (HF). The aim of this pilot study was to determine the feasibility and efficacy of aquatic exercise training during a maintenance phase for a clinical heart failure population. METHODS: In this 2 x 2 crossover design trial, individuals who had previously completed HF rehabilitation were randomised into either a land-based or aquatic training program once per week for six weeks, after which time they changed to the alternate exercise training protocol for an additional six weeks...
November 30, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27987463/a-taxonomy-of-chemicals-of-emerging-concern-based-on-observed-fate-at-water-resource-recovery-facilities
#7
Steven M Jones, Zaid K Chowdhury, Michael J Watts
As reuse of municipal water resource recovery facility (WRRF) effluent becomes vital to augment diminishing fresh drinking water resources, concern exists that conventional barriers may prove deficient, and the upcycling of chemicals of emerging concern (CECs) could prove harmful to human health and aquatic species if more effective and robust treatment barriers are not in place. A multiple month survey, of both primary and secondary effluents, from three (3) WRRFs, for 95 CECs was conducted in 2014 to classify CECs by their persistence through conventional water reclamation processes...
March 2017: Chemosphere
https://www.readbyqxmd.com/read/27965017/structure-and-functionalities-of-the-human-c-reactive-protein-compared-to-the-zebrafish-multigene-family-of-c-reactive-like-proteins
#8
REVIEW
Melissa Bello-Perez, Alberto Falco, Regla Medina, Jose Antonio Encinar, Beatriz Novoa, Luis Perez, Amparo Estepa, Julio Coll
Because of the recent discovery of multiple c-reactive protein (crp)-like genes in zebrafish (Danio rerio) with predicted heterogeneous phospholipid-binding amino acid sequences and heterogeneous transcript expression levels in viral survivors and adaptive-deficient mutants, zebrafish constitute an attractive new model for exploring the evolution of these protein's functions, including their possible participation in fish trained immunity. Circulating human CRP belongs to the short pentraxin family of oligomeric proteins that are characteristic of early acute-phase innate responses and is widely used as a clinical inflammation marker...
December 10, 2016: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/27914646/in-the-eye-of-the-beholder-assessing-the-water-quality-of-shoreline-parks-around-the-island-of-montreal-through-citizen-science
#9
D Lévesque, A Cattaneo, G Deschamps, C Hudon
As a part of the FreshWater Watch project aiming to promote volunteers' water monitoring in 25 cities around the world, St. Lawrence River water quality was characterized at 28 public shoreline parks around Montreal Island, Quebec, Canada. This involved training of 69 citizen scientists by researchers of the Université de Montréal in five one-day sessions. Shoreline sampling yielded 174 data points over three summers (May 2013 to November 2015). Water turbidity, nitrate and phosphate concentrations were measured in situ, together with the thickness and type of beach-cast vegetation, and the relative abundance of different types of beach litter...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27889766/telencephalic-neuronal-activation-associated-with-spatial-memory-in-the-terrestrial-toad-rhinella-arenarum-participation-of-the-medial-pallium-during-navigation-by-geometry
#10
María Inés Sotelo, M Florencia Daneri, Verner Peter Bingman, Rubén N Muzio
Amphibians are central to discussions of vertebrate evolution because they represent the transition from aquatic to terrestrial life, a transition with profound consequences for the selective pressures shaping brain evolution. Spatial navigation is one class of behavior that has attracted the interest of comparative neurobiologists because of the relevance of the medial pallium/hippocampus, yet, surprisingly, in this regard amphibians have been sparsely investigated. In the current study, we trained toads to locate a water goal relying on the boundary geometry of a test environment (Geometry-Only) or boundary geometry coupled with a prominent, visual feature cue (Geometry-Feature)...
November 26, 2016: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/27886151/micro-doppler-based-classification-of-human-aquatic-activities-via-transfer-learning-of-convolutional-neural-networks
#11
Jinhee Park, Rios Jesus Javier, Taesup Moon, Youngwook Kim
Accurate classification of human aquatic activities using radar has a variety of potential applications such as rescue operations and border patrols. Nevertheless, the classification of activities on water using radar has not been extensively studied, unlike the case on dry ground, due to its unique challenge. Namely, not only is the radar cross section of a human on water small, but the micro-Doppler signatures are much noisier due to water drops and waves. In this paper, we first investigate whether discriminative signatures could be obtained for activities on water through a simulation study...
November 24, 2016: Sensors
https://www.readbyqxmd.com/read/27852157/acute-and-chronic-effects-of-aquatic-treadmill-training-on-land-treadmill-running-kinematics-a-cross-over-and-single-subject-design-approach
#12
Eadric Bressel, Talin J Louder, James P Hoover, Luke C Roberts, Dennis G Dolny
The aim of this study was to determine if selected kinematic measures (foot strike index [SI], knee contact angle and overstride angle) were different between aquatic treadmill (ATM) and land treadmill (LTM) running, and to determine if these measures were altered during LTM running as a result of 6 weeks of ATM training. Acute effects were tested using 15 competitive distance runners who completed 1 session of running on each treadmill type at 5 different running speeds. Subsequently, three recreational runners completed 6 weeks of ATM training following a single-subject baseline, intervention and withdrawal experiment...
November 17, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27847147/a-novel-single-parameter-approach-for-forecasting-algal-blooms
#13
Xi Xiao, Junyu He, Haomin Huang, Todd R Miller, George Christakos, Elke S Reichwaldt, Anas Ghadouani, Shengpan Lin, Xinhua Xu, Jiyan Shi
Harmful algal blooms frequently occur globally, and forecasting could constitute an essential proactive strategy for bloom control. To decrease the cost of aquatic environmental monitoring and increase the accuracy of bloom forecasting, a novel single-parameter approach combining wavelet analysis with artificial neural networks (WNN) was developed and verified based on daily online monitoring datasets of algal density in the Siling Reservoir, China and Lake Winnebago, U.S.A. Firstly, a detailed modeling process was illustrated using the forecasting of cyanobacterial cell density in the Chinese reservoir as an example...
January 1, 2017: Water Research
https://www.readbyqxmd.com/read/27830479/acute-aquatic-toxicity-of-organic-solvents-modeled-by-qsars
#14
A Levet, C Bordes, Y Clément, P Mignon, C Morell, H Chermette, P Marote, P Lantéri
To limit in vivo experiments, the use of quantitative structure-activity relationships (QSARs) is advocated by REACH regulation to predict the required fish, invertebrate, and algae EC50 for chemical registration. The aim of this work was to develop reliable QSARs in order to model both invertebrate and algae EC50 for organic solvents, regardless of the mechanism of toxic action involved. EC50 represents the concentration producing the 50 % immobilization of invertebrates or the 50 % growth inhibition of algae...
December 2016: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/27807516/the-morphological-and-functional-effects-of-exercise-in-the-aquatic-environment-performed-before-and-or-after-sciatic-nerve-compression-in-wistar-rats
#15
Camila Mayumi Martin Kakihata, Jéssica Aline Malanotte, Jhenifer Karvat, Rose Meire Costa Brancalhão, Lucinéia de Fátima Chasko Ribeiro, Gladson Ricardo Flor Bertolini
The aim of this study was to evaluate the effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats on morphological and functional parameters. Twenty-five Wistar rats were divided into the following groups: control (C), lesion (L), trained+lesion (TL), lesion+exercise (LE), and training+lesion+exercise (TLE), who underwent right sciatic nerve compression on day 21 of the experiment. The TL and TLE groups were submitted to a jumping exercise in a water environment for 20 days prior to injury and the LE and TLE groups after injury...
October 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/27779918/producing-interdisciplinary-competent-professionals-integrating-one-health-core-competencies-into-the-veterinary-curriculum-at-the-university-of-rwanda
#16
Hellen J Amuguni, Melissa Mazan, Robert Kibuuka
Infectious diseases of grave concern to human health are emerging from wildlife and livestock populations in multiple regions of the world. Responding effectively to these emerging pandemics requires engagement of multidisciplinary groups of professionals. Using a One Health approach, One Health Central and Eastern Africa (OHCEA), a network of seven schools of public health and seven veterinary schools, with the support of the United States Agency for International Development (USAID), has engaged in curriculum review with the aim of building the skills of multidisciplinary groups of professionals to improve their capacity to respond to emerging infectious diseases...
October 25, 2016: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/27710837/the-influence-of-the-aquatic-environment-on-the-control-of-postural-sway
#17
Andresa R Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C Verrier, Milos R Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain...
January 2017: Gait & Posture
https://www.readbyqxmd.com/read/27669180/reliability-and-accuracy-of-a-standardized-shallow-water-running-test-to-determine-cardiorespiratory-fitness
#18
Elizabeth F Nagle, Mary E Sanders, Bethany B Gibbs, Barry A Franklin, Jacquelyn A Nagle, Philip J Prins, Caleb D Johnson, Robert J Robertson
A standardized fitness assessment is critical for the development of an individualized exercise prescription. Although the benefits of aquatic exercise have been well established, there remains the need for a standardized non-swimming protocol to accurately assess cardiorespiratory fitness (CRF) in shallow water. The present investigation was designed to assess: 1) reliability of a standardized Shallow Water Run (SWR) test of CRF; and 2) accuracy of a standardized SWR compared with a land-based treadmill test (LTM)...
September 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27668720/prediction-of-acute-toxicity-of-phenol-derivatives-using-multiple-linear-regression-approach-for-tetrahymena-pyriformis-contaminant-identification-in-a-median-size-database
#19
Karel Dieguez-Santana, Hai Pham-The, Pedro J Villegas-Aguilar, Huong Le-Thi-Thu, Juan A Castillo-Garit, Gerardo M Casañola-Martin
In this article, the modeling of inhibitory grown activity against Tetrahymena pyriformis is described. The 0-2D Dragon descriptors based on structural aspects to gain some knowledge of factors influencing aquatic toxicity are mainly used. Besides, it is done by some enlarged data of phenol derivatives described for the first time and composed of 358 chemicals. It overcomes the previous datasets with about one hundred compounds. Moreover, the results of the model evaluation by the parameters in the training, prediction and validation give adequate results comparable with those of the previous works...
December 2016: Chemosphere
https://www.readbyqxmd.com/read/27666160/effectiveness-of-aquatic-exercise-in-improving-lower-limb-strength-in-musculoskeletal-conditions-a-systematic-review-and-meta-analysis
#20
REVIEW
Sophie Heywood, Jodie McClelland, Benjamin Mentiplay, Paula Geigle, Ann Rahmann, Ross Clark
OBJECTIVE: To investigate the effectiveness of aquatic exercise in improving lower limb strength in people with musculoskeletal conditions. DATA SOURCES: A systematic search used 5 databases, including MEDLINE, CINAHL, Embase, SPORTDiscus, and The Cochrane Library. STUDY SELECTION: Randomized controlled trials evaluating aquatic exercise with a resistance training component for adults with musculoskeletal conditions compared with no intervention or land-based exercise were identified...
January 2017: Archives of Physical Medicine and Rehabilitation
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