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Transcranial sonography

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https://www.readbyqxmd.com/read/28207907/argon-does-not-affect-cerebral-circulation-or-metabolism-in-male-humans
#1
Frank Grüne, Stephan Kazmaier, Sanne Elisabeth Hoeks, Robert Jan Stolker, Marc Coburn, Andreas Weyland
OBJECTIVE: Accumulating data have recently underlined argon´s neuroprotective potential. However, to the best of our knowledge, no data are available on the cerebrovascular effects of argon (Ar) in humans. We hypothesized that argon inhalation does not affect mean blood flow velocity of the middle cerebral artery (Vmca), cerebral flow index (FI), zero flow pressure (ZFP), effective cerebral perfusion pressure (CPPe), resistance area product (RAP) and the arterio-jugular venous content differences of oxygen (AJVDO2), glucose (AJVDG), and lactate (AJVDL) in anesthetized patients...
2017: PloS One
https://www.readbyqxmd.com/read/28193836/post-subdural-hematoma-transient-ischemic-attacks-hypoperfusion-mechanism-supported-by-quantitative-electroencephalography-and-transcranial-doppler-sonography
#2
Ayham M Alkhachroum, Guadalupe Fernandez-Baca Vaca, Sophia Sundararajan, Michael DeGeorgia
No abstract text is available yet for this article.
February 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28187816/multimodal-neurologic-monitoring
#3
G Korbakis, P M Vespa
Neurocritical care has two main objectives. Initially, the emphasis is on treatment of patients with acute damage to the central nervous system whether through infection, trauma, or hemorrhagic or ischemic stroke. Thereafter, attention shifts to the identification of secondary processes that may lead to further brain injury, including fever, seizures, and ischemia, among others. Multimodal monitoring is the concept of using various tools and data integration to understand brain physiology and guide therapeutic interventions to prevent secondary brain injury...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28181956/extrapyramidal-symptoms-in-schizophrenia-evidence-of-blunted-cerebral-hemodynamics-during-a-planning-task
#4
Daniel Schuepbach, Matthias Michel, Gert Wagner, Stefan Duschek, Sabine C Herpertz
Acute extrapyramidal symptoms (EPS) occur frequently in schizophrenia, mostly caused by antidopaminergic substances. There have been no published reports on the impact of acute EPS on cerebral blood flow (CBF) or related measures. In the following study, we examined schizophrenic patients with and without EPS during a planning task and measurements of CBF velocity. Sixteen patients with chronic schizophrenia and 16 healthy participants performed a planning paradigm during bilateral functional transcranial Doppler sonography of the middle cerebral arteries...
February 8, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28127789/transcranial-doppler-monitoring-in-carotid-endarterectomy-a-systematic-review-and-meta-analysis
#5
Reshmi Udesh, Piruthiviraj Natarajan, Karthy Thiagarajan, Lawrence R Wechsler, Donald J Crammond, Jeffrey R Balzer, Parthasarathy D Thirumala
OBJECTIVES: To evaluate the efficacy of intraoperative transcranial Doppler monitoring in predicting perioperative strokes after carotid endarterectomy (CEA). METHODS: An electronic search of PubMed, Embase, and Web of Science databases was conducted for studies on transcranial Doppler monitoring in CEA published from January 1970 through September 2015. All titles and abstracts were independently screened on the basis of predetermined inclusion criteria, which included randomized clinical trials and prospective or retrospective cohort reviews, patients who underwent CEA with intraoperative transcranial Doppler monitoring (either middle cerebral artery velocity [MCAV] or cerebral microembolic signals [MES]) and postoperative neurologic assessments up to 30 days after the surgery, and studies including an abstract, published in English on adult humans 18 years and older with a sample size of 50 or greater...
January 27, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28108264/iron-accumulation-and-microglia-activation-contribute-to-substantia-nigra-hyperechogenicity-in-the-6-ohda-induced-rat-model-of-parkinson-s-disease
#6
Yaqin Zhu, Bao Wang, Kai Tao, Hengli Yang, Yixiao Wang, Tian Zhou, Yilin Yang, Lijun Yuan, Xi Liu, Yunyou Duan
INTRODUCTION: This study aims to explain the mechanisms for the formation of sonographic features of Parkinson's disease (PD) using a 6-hydroxydopamine (6-OHDA) rat model of PD. The iron chelator deferiprone (DFP) was used in the PD model rat to examine the relationship between iron and the echo signal. METHODS: Rat models were created using stereotactic injections of 6-OHDA. DFP was administered intragastrically. Transcranial sonography (TCS) was performed to observe the substantia nigra (SN) echo signal of the brain...
January 6, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28094105/sonographic-alteration-of-substantia-nigra-is-related-to-parkinsonism-predominant-course-of-x-linked-dystonia-parkinsonism
#7
Uwe Walter, Raymond Rosales, Alessandro Rocco, Ana Westenberger, Aloysius Domingo, Criscely L Go, Norbert Brüggemann, Christine Klein, Lillian V Lee, Dirk Dressler
INTRODUCTION: X-linked recessive dystonia-parkinsonism (XDP, DYT3) is highly prevalent in the Philippines and manifests with varying phenotype. We sought to evaluate the significance of transcranial brain sonography as a biomarker for parkinsonism-predominant phenotype. METHODS: 90 Filipino participants were enrolled into a cross-sectional study: 39 patients with XDP, 21 asymptomatic first-degree relatives of XDP patients, and 30 healthy control subjects. Echogenicity of the substantia nigra and the lenticular nuclei was digitally quantified...
January 10, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28088127/cerebral-laterality-for-language-is-related-to-adult-salivary-testosterone-levels-but-not-digit-ratio-2d-4d-in-men-a-functional-transcranial-doppler-ultrasound-study
#8
Marietta Papadatou-Pastou, Maryanne Martin
The adequacy of three competing theories of hormonal effects on cerebral laterality are compared using functional transcranial Doppler sonography (fTCD). Thirty-three adult males participated in the study (21 left-handers). Cerebral lateralization was measured by fTCD using an extensively validated word generation task. Adult salivary testosterone (T) and cortisol (C) concentrations were measured by luminescence immunoassay and prenatal T exposure was indirectly estimated by the somatic marker of 2nd to 4th digit length ratio (2D:4D)...
January 11, 2017: Brain and Language
https://www.readbyqxmd.com/read/28025360/patterns-of-cerebral-blood-flow-modulation-during-painful-stimulation-in-fibromyalgia-a-transcranial-doppler-sonography-study
#9
Casandra I Montoro, Stefan Duschek, Cristina Muñóz Ladrón de Guevara, Gustavo A Reyes Del Paso
OBJECTIVE: This study analyzed the temporal dynamics of cerebral blood flow (CBF) modulations, during painful stimulation in fibromyalgia syndrome (FMS), using functional transcranial Doppler sonography. METHOD: Blood flow velocities were recorded bilaterally in the anterior (ACA) and middle (MCA) cerebral arteries of 24 FMS patients and 20 healthy individuals during exposure to painful pressure stimulation. Participants were presented with two stimulation blocks: a) fixed pressure (2...
December 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27903331/biomarkers-in-prodromal-parkinson-disease-a-qualitative-review
#10
Christine A Cooper, Lama M Chahine
BACKGROUND: Over the past several years, the concept of prodromal Parkinson disease (PD) has been increasingly recognized. This term refers to individuals who do not fulfill motor diagnostic criteria for PD, but who have clinical, genetic, or biomarker characteristics suggesting risk of developing PD in the future. Clinical diagnosis of prodromal PD has low specificity, prompting the need for objective biomarkers with higher specificity. In this qualitative review, we discuss objectively defined putative biomarkers for PD and prodromal PD...
November 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27898200/transcranial-sonography-in-idiopathic-rem-sleep-behavior-disorder-and-multiple-system-atrophy
#11
Xudong Li, Shuang Xue, Shuhong Jia, Zhi Zhou, Yanan Qiao, Chunlei Hou, Kun Wei, Wenjing Zheng, Pei Rong, Jinsong Jiao
AIM: We investigated preclinical abnormalities as revealed by transcranial sonography (TCS) in patients with idiopathic rapid eye movement sleep behavior disorder (iRBD) compared with those revealed in patients with multiple system atrophy (MSA) or Parkinson's disease (PD) and in normal controls. METHODS: Twenty-two patients with iRBD, 21 patients with MSA, 22 patients with PD, and 21 normal controls were included in this study. All participants underwent one night of video-polysomnography monitoring, and the sleep parameters were analyzed using P olysmith software and by visual analysis...
November 29, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27888722/a-pilot-study-on-predictors-of-brainstem-raphe-abnormality-in-patients-with-major-depressive-disorder
#12
Milutin Kostić, Ana Munjiza, Danilo Pesic, Amir Peljto, Ivana Novakovic, Valerija Dobricic, Dusica Lecic Tosevski, Milija Mijajlovic
BACKGROUND: Hypo/anechogenicity of the brainstem raphe (BR) structures has been suggested as a possible transcranial parenchymal sonography (TCS) marker associated with depression. AIM: The aim of this study was to analyze possible association of the abnormal BR echogenicity in patients with major depression when compared to healthy controls, and to evaluate its clinical and genetic correlates. METHODS: TCS was performed in 53 patients diagnosed as major depressive disorder (MDD) without psychotic symptoms and in 54 healthy matched controls...
February 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27857051/elevation-of-the-acth-cortisol-ratio-in-female-opioid-dependent-patients-a-biomarker-of-aging-and-correlate-of-metabolic-and-immune-activation
#13
Albert Stuart Reece, Gary Kenneth Hulse
BACKGROUND: Whilst the hypothalamic-pituitary-adrenal (HPA) Axis is a major stress axis, and is necessarily perturbed in opioid dependency, and stress is a major contributor to aging mechanisms, the HPA axis has not been studied in opioid dependency in an age-dependent manner. OBJECTIVE: Hypothesis - Differences in age dependent levels of HPA components. DESIGN: Cross-sectional comparison of general medical and opioid dependent patients (ODP, GMP)...
September 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/27837189/middle-cerebral-artery-diameter-changes-during-rhythmic-handgrip-exercise-in-humans
#14
J Verbree, Agt Bronzwaer, M A van Buchem, Mjap Daemen, J J van Lieshout, Mjp van Osch
Transcranial Doppler (TCD) sonography is a frequently employed technique for quantifying cerebral blood flow by assuming a constant arterial diameter. Given that exercise increases arterial pressure by sympathetic activation, we hypothesized that exercise might induce a change in the diameter of large cerebral arteries. Middle cerebral artery (MCA) cross-sectional area was assessed in response to handgrip exercise by direct magnetic resonance imaging (MRI) observations. Twenty healthy subjects (11 female) performed three 5 min bouts of rhythmic handgrip exercise at 60% maximum voluntary contraction, alternated with 5 min of rest...
November 11, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27812167/usefulness-of-cardiac-mibg-scintigraphy-olfactory-testing-and-substantia-nigra-hyperechogenicity-as-additional-diagnostic-markers-for-distinguishing-between-parkinson-s-disease-and-atypical-parkinsonian-syndromes
#15
Hiroaki Fujita, Keisuke Suzuki, Ayaka Numao, Yuji Watanabe, Tomoyuki Uchiyama, Tomoyuki Miyamoto, Masayuki Miyamoto, Koichi Hirata
BACKGROUND: We aimed to evaluate the utility of the combined use of cardiac 123I-metaiodobenzylguanidine (MIBG) scintigraphy, olfactory testing, and substantia nigra (SN) hyperechogenicity on transcranial sonography (TCS) in differentiating Parkinson's disease (PD) from atypical parkinsonian syndromes (APSs), such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). METHODS: Cardiac MIBG scintigraphy, card-type odor identification testing (Open Essence (OE), Wako, Japan), and TCS were performed with 101 patients with PD and 38 patients with APSs (MSA and PSP)...
2016: PloS One
https://www.readbyqxmd.com/read/27790125/a-case-of-turner-syndrome-with-multiple-embolic-infarcts
#16
Cindy W Yoon, Eungseok Lee, Byung-Nam Yoon, Hee-Kwon Park, Joung-Ho Rha
Only a few cases of Turner syndrome (TS) with ischemic stroke have been reported. Various arteriopathies of the cerebral arteries, including fibromuscular dysplasia, congenital hypoplasia, moyamoya syndrome, and premature atherosclerosis have been assumed to be the cause of ischemic stroke in TS. There has been no case report of a TS patient presenting with an embolic stroke pattern without any cerebral arteriopathy. A 28-year-old woman with TS was referred to our hospital because of abnormal brain magnetic resonance imaging (MRI) findings...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/27750247/transcranial-sonography-and-datscan-in-early-stage-parkinson-s-disease-and-essential-tremor
#17
Joana Jesus-Ribeiro, António Freire, João Sargento-Freitas, Mário Sousa, Fernando Silva, Fradique Moreira, Maria João Cunha, Uwe Walter, Cristina Januário
BACKGROUND: The diagnosis of Parkinson's disease (PD) can sometimes be a challenge in the early stages of the disease. Both transcranial sonography (TCS) and DaTSCAN are recommended as auxiliary examinations for the differential diagnosis of PD; however, only few data exist regarding their diagnostic accuracy in the early stage of PD and essential tremor (ET). METHODS: We evaluated patients with clinically suspected diagnosis of PD at early stages (Hoehn and Yahr ≤2) or ET...
2016: European Neurology
https://www.readbyqxmd.com/read/27740993/ultrasound-in-neurology
#18
Georgios Tsivgoulis, Andrei V Alexandrov
PURPOSE OF REVIEW: Low cost, avoidance of irradiation, and high temporal resolution are inherent advantages of ultrasound imaging that translate into multiple clinical uses in many domains of neurology. This article presents clinical uses of ultrasound examination in cerebrovascular, neurodegenerative, and peripheral nervous system diseases. RECENT FINDINGS: Modern treatment and prevention of ischemic stroke rely on prompt diagnosis. Ultrasonography has found a place as a noninvasive screening test and bedside technique that provides estimates of the degree of stenosis as well as hemodynamic and structural information about intracranial and extracranial vessels in real time...
October 2016: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/27731537/transcranial-sonography-in-dopa-responsive-dystonia
#19
M Svetel, A Tomić, M Mijajlović, V Dobričić, I Novaković, T Pekmezović, L Brajković, V S Kostić
BACKGROUND AND PURPOSE: Mutations in the GCH1 gene, encoding GTP cyclohydrolase 1, the enzyme critically important for dopamine production in nigrostriatal neurons, are the most common cause of dopa-responsive dystonia (DRD), characterized predominantly by limb dystonia, although parkinsonian features may also be present. It has been suggested that DRD is a neurochemical rather than neurodegenerative disorder. METHODS: Transcranial brain sonography, which might be a risk marker for nigral injury, was obtained from 141 subjects divided into four groups: (i) 11 patients with genetically confirmed DRD; (ii) 55 consecutive patients with Parkinson's disease (PD); (iii) 30 patients diagnosed as isolated adult-onset focal dystonia; and (iv) 45 healthy controls (HCs)...
January 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27699751/-diagnostic-prognostic-and-therapeutic-implications-of-transcranial-color-coded-duplex-sonography-in-acute-ischemic-stroke-tibi-and-cogif-scores-validation
#20
P Sobrino-Garcia, A Garcia-Pastor, A Garcia-Arratibel, R Dominguez-Rubio, P M Rodriguez-Cruz, A M Iglesias-Mohedano, F Diaz-Otero, P Vazquez-Alen, Y Fernandez-Bullido, J A Villanueva-Osorio, A Gil-Nunez
AIM: To describe the information provided by transcranial color-coded duplex (TCCD) sonography for therapeutic decision-making in patients with acute ischemic stroke and to analyze the relationship between TCCD findings and the severity and prognosis of stroke. PATIENTS AND METHODS: TCCD performed within the six first hours after an acute ischemic stroke were analyzed in our institution. The presence of an arterial occlusion and its location were collected using TIBI (Thrombolysis in Brain Ischemia) and COGIF (Consensus on Grading Intracranial Flow Obstruction) criteria...
October 16, 2016: Revista de Neurologia
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