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subjective organ function assessment

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https://www.readbyqxmd.com/read/28430717/multilateral-functional-alterations-of-human-neutrophils-in-sepsis-from-the-point-of-diagnosis-to-the-seventh-day
#1
Akira Endo, Miko Okamura, Shunsuke Yoshikawa, Yasuhiro Otomo, Tomohiro Morio
Neutrophil functional changes caused by sepsis itself and their time-course variation have not been fully elucidated because previous studies targeted patients who had received therapeutic interventions. We explored the multilateral functions of circulating neutrophils in patients with severe sepsis or septic shock who had not yet undergone interventions, and followed their changes. Patients were treated based on the Surviving Sepsis Campaign Guidelines 2012. Neutrophil functions were evaluated on days 0 (before therapeutic intervention), 3, and 7 in fifty-nine sepsis patients...
April 20, 2017: Shock
https://www.readbyqxmd.com/read/28415121/p1113relationship-between-left-atrium-and-hypertensive-retinopathy-in-patients-with-systemic-hypertension-a-real-time-three-dimensional-echocardiography-based-study
#2
B Kanar, H S Kanar, A Karatay, M K Tigen
Background: The fundoscopic examination of hypertensive patients, which is an established hypertension-related target organ damage (TOD), tends to be underutilized in clinical practice. We sought to investigate the relationship between retinal alterations and left atrium (LA) volumes by means of real-time, three-dimensional echocardiography (RT3DE), which is the most pivotal predictor of diastolic dysfunction. Methods: Our population consisted of 88 consecutive essential hypertensive patients (age 59...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28401633/functional-soil-metagenomics-elucidation-of-polycyclic-aromatic-hydrocarbon-degradation-potential-following-12-years-of-in-situ-bioremediation
#3
Márcia Duarte, Agnes Nielsen, Amélia Camarinha-Silva, Ramiro Vilchez-Vargas, Thomas Bruls, Melissa L Wos-Oxley, Ruy Jauregui, Dietmar H Pieper
A culture-independent function-based screening approach was used to assess the microbial aerobic catabolome for polycyclic aromatic hydrocarbons degradation of a soil subjected to 12 years of in situ bioremediation. A total of 422,750 fosmid clones were screened for key aromatic ring-cleavage activities using 2,3-dihydroxybiphenyl as substrate. Most of the genes encoding ring-cleavage enzymes on the 768 retrieved positive fosmids could not be identified using primer-based approaches and, thus, 205 fosmid inserts were sequenced...
April 12, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28377150/developmental-changes-in-autonomic-responses-are-associated-with-future-reward-punishment-expectations-a-study-of-sympathetic-skin-responses-in-the-markov-decision-task
#4
Hiromi Hosaka, Kakuro Aoyagi, Yoshimi Kaga, Hideaki Kanemura, Kanji Sugita, Masao Aihara
OBJECTIVE: Autonomic nervous system activity is recognized as a major component of emotional responses. Future reward/punishment expectations depend upon the process of decision making in the frontal lobe, which is considered to play an important role in executive function. The aim of this study was to investigate the relationship between autonomic responses and decision making during reinforcement tasks using sympathetic skin responses (SSR). METHODS: Nine adult and 9 juvenile (mean age, 10...
April 1, 2017: Brain & Development
https://www.readbyqxmd.com/read/28376835/indoor-air-pollution-and-its-association-with-poor-lung-function-microalbuminuria-and-variations-in-blood-pressure-among-kitchen-workers-in-india-a-cross-sectional-study
#5
Amarnath Singh, Chandrasekharan Nair Kesavachandran, Ritul Kamal, Vipin Bihari, Afzal Ansari, Parappurath Abdul Azeez, Prem Narain Saxena, Anil Kumar Ks, Altaf Hussain Khan
BACKGROUND: The present study is an attempt to explore the association between kitchen indoor air pollutants and physiological profiles in kitchen workers with microalbuminuria (MAU) in north India (Lucknow) and south India (Coimbatore). METHODS: The subjects comprised 145 control subjects, 233 kitchen workers from north India and 186 kitchen workers from south India. Information related to the personal and occupational history and health of the subjects at both locations were collected using a custom-made questionnaire...
April 4, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28366286/effect-of-paracetamol-acetaminophen-on-body-temperature-in-acute-stroke-a-meta-analysis
#6
Junjie Fang, Chensong Chen, Hongsen Cheng, Ren Wang, Linhao Ma
PURPOSE: The objective of this study was to assess the efficacy of paracetamol (acetaminophen) on body temperature in acute stroke. METHODS: Medline, Cochrane Central Register of Controlled Trials, EMBASE, Chinese BioMedical Literature Database, China National Knowledge Infrastructure, and the World Health Organization (WHO) International Clinical Trials Registry Platform were searched electronically. Relevant journals and references of studies included were hand-searched for randomized controlled trials (RCT) and controlled clinical trials (CCT) regarding the efficacy of paracetamol (acetaminophen) on body temperature in acute stroke...
March 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28360350/myocardial-viability-survival-mechanisms-and-molecular-imaging-targets-in-acute-and-chronic-ischemia
#7
REVIEW
Henry Gewirtz, Vasken Dilsizian
Myocardial responses to acute ischemia/reperfusion and to chronic ischemic conditions have been studied extensively at all levels of organization. These include subcellular (eg, mitochondria in vitro); intact, large animal models (eg, swine with chronic coronary stenosis); as well as human subjects. Investigations in humans have used positron emission tomographic metabolic and myocardial blood flow measurements, assessment of gene expression and anatomic description of myocardium obtained at the time of coronary artery revascularization, ventricular assist device placement, or heart transplantation...
March 31, 2017: Circulation Research
https://www.readbyqxmd.com/read/28351601/-organic-troubles-with-psychiatric-symptoms-what-is-the-appropriate-childhood-and-adolescence-psychiatric-care-reflections-on-disimmune-encephalitis-cases
#8
R Ozelle, A Doudard, A-L Bodin, S Gueden, P Duverger, E Riquin
Organic mental disorders are different and further revealed by increasingly advanced research. They are nevertheless misunderstood, without consensus, and raise clinical, diagnostic, and therapeutic questions. These disorders require effective collaboration between practitioners such as pediatricians and child psychiatrists. The subject should not disappear behind the complexity related to the clinical expression of these symptoms. Based on three cases of autoimmune encephalitis, we offer a reflection on the management and assessment of these diseases by a multidisciplinary team with the intention of providing optimal management...
May 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28348547/altered-cervical-vestibular-evoked-myogenic-potential-in-children-with-attention-deficit-and-hyperactivity-disorder
#9
Valeria Isaac, Diego Olmedo, Francisco Aboitiz, Paul H Delano
OBJECTIVE: Emerging evidence suggests that children with attention deficit and hyperactivity disorder (ADHD) present more difficulties in standing and walking balance than typically developing children. Most of previous studies have assessed these functions using postural and sensory organization tests showing differences in balance performance between control and ADHD children. However, to date, it is unknown whether these balance alterations are accompanied with vestibular dysfunction...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28345784/quality-of-life-in-cervical-cancer-survivors-and-healthy-women-thai-urban-population-study
#10
Pichita Prasongvej, Tongta Nanthakomon, Kankamol Jaisin, Athita Chanthasenanont, Supapen Lertvutivivat, Chamnan Tanprasertkul, Kornkarn Bhamarapravatana, Komsun Suwannarurk
Background : To determine a baseline quality of life (QoL) in cervical cancer survivors compared to that of healthy subjects in the tertiary Thammasat University Hospital, Thailand. Materials and Methods: The investigation was conducted at the outpatient gynecological department of Thammasat University Hospital between January and June 2016. A total of 192 women were entered into the study (97 cervical cancer survivors; 37 after radical hysterectomy (RH), 43 with concurrent chemoradiation (CRT), and 17 featuring both RH and CRT; and 95 control subjects from the same outpatient department with no history of malignancy)...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28339994/a-longitudinal-cohort-study-of-the-anti-synthetase-syndrome-increased-severity-of-interstitial-lung-disease-in-black-patients-and-patients-with-anti-pl7-and-anti-pl12-autoantibodies
#11
Iago Pinal-Fernandez, Maria Casal-Dominguez, Julio A Huapaya, Jemima Albayda, Julie J Paik, Cheilonda Johnson, Leann Silhan, Lisa Christopher-Stine, Andrew L Mammen, Sonye K Danoff
Objective.: The aim was to study the prevalence, rate of appearance and severity of clinical features in patients with different anti-synthetase syndrome (ASyS) autoantibodies. Methods.: All Johns Hopkins Myositis Longitudinal Cohort subjects positive for any ASyS autoantibodies were included. Clinical information, including symptoms, signs, strength, creatine kinase concentrations and pulmonary function tests, were prospectively collected. The standardized mortality and cancer rates and the rate of appearance and intensity of the different organ manifestations were assessed using univariate and multivariate analysis and compared between ASyS autoantibodies...
March 4, 2017: Rheumatology
https://www.readbyqxmd.com/read/28337552/clinical-utility-of-resting-state-functional-connectivity-magnetic-resonance-imaging-for-mood-and-cognitive-disorders
#12
REVIEW
T Takamura, T Hanakawa
Although functional magnetic resonance imaging (fMRI) has long been used to assess task-related brain activity in neuropsychiatric disorders, it has not yet become a widely available clinical tool. Resting-state fMRI (rs-fMRI) has been the subject of recent attention in the fields of basic and clinical neuroimaging research. This method enables investigation of the functional organization of the brain and alterations of resting-state networks (RSNs) in patients with neuropsychiatric disorders. Rs-fMRI does not require participants to perform a demanding task, in contrast to task fMRI, which often requires participants to follow complex instructions...
March 23, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28336261/methane-rescues-retinal-ganglion-cells-and-limits-retinal-mitochondrial-dysfunction-following-optic-nerve-crush
#13
Ruobing Wang, Qinglei Sun, Fangzhou Xia, Zeli Chen, Jiangchun Wu, Yuelu Zhang, Jiajun Xu, Lin Liu
Secondary degeneration is a common event in traumatic central nervous system disorders, which involves neuronal apoptosis and mitochondrial dysfunction. Exogenous methane exerts the therapeutic effects in many organ injury. Our study aims to investigate the potential neuroprotection of methane in a rat model of optic nerve crush (ONC). Adult male Sprague-Dawley rats were subjected to ONC and administrated intraperitoneally with methane-saturated or normal saline (10 ml/kg) once per day for one week after ONC...
March 20, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28325448/diagnosis-of-autism-through-eeg-processed-by-advanced-computational-algorithms-a-pilot-study
#14
Enzo Grossi, Chiara Olivieri, Massimo Buscema
BACKGROUND: Multi-Scale Ranked Organizing Map coupled with Implicit Function as Squashing Time algorithm(MS-ROM/I-FAST) is a new, complex system based on Artificial Neural networks (ANNs) able to extract features of interest in computerized EEG through the analysis of few minutes of their EEG without any preliminary pre-processing. A proof of concept study previously published showed accuracy values ranging from 94%-98% in discerning subjects with Mild Cognitive Impairment and/or Alzheimer's Disease from healthy elderly people...
April 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28325028/tracking-intrinsic-connectivity-brain-network-features-during-successive-pseudo-resting-states-and-interoceptive-task-fmri
#15
Behnaz Jarrahi, Dante Mantini
Advanced multivariate analyses of functional magnetic resonance imaging (fMRI) data based on blood oxygen level-dependent (BOLD) contras have revealed that the human brain organizes its activities into multiple intrinsic connectivity networks (ICNs). Several fMRI studies have evaluated the modulations of these networks during different cognitive or emotional tasks using blind source separation techniques particularly the independent component analysis (ICA). In this exploratory study, we applied ICA methodology to examine ICN modulations under different interoceptive conditions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28317909/the-active-side-of-stereopsis-fixation-strategy-and-adaptation-to-natural-environments
#16
Agostino Gibaldi, Andrea Canessa, Silvio P Sabatini
Depth perception in near viewing strongly relies on the interpretation of binocular retinal disparity to obtain stereopsis. Statistical regularities of retinal disparities have been claimed to greatly impact on the neural mechanisms that underlie binocular vision, both to facilitate perceptual decisions and to reduce computational load. In this paper, we designed a novel and unconventional approach in order to assess the role of fixation strategy in conditioning the statistics of retinal disparity. We integrated accurate realistic three-dimensional models of natural scenes with binocular eye movement recording, to obtain accurate ground-truth statistics of retinal disparity experienced by a subject in near viewing...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28293731/physical-function-and-health-related-quality-of-life-in-patients-undergoing-surgical-treatment-for-malignant-pleural-mesothelioma
#17
Takashi Tanaka, Shinichiro Morishita, Masaki Hashimoto, Yusuke Itani, Satoshi Mabuchi, Norihiko Kodama, Seiki Hasegawa, Kazuhisa Domen
INTRODUCTION: Malignant pleural mesothelioma (MPM) is a rare cancer that affects the thin cell wall lining of internal organs and structures. Studies have shown that patients with lung cancer have decreased pulmonary function and exercise capacity after pneumonectomy. However, to date, physical function and health-related quality of life (HRQOL) in surgically treated MPM patients have not been evaluated in detail. The aim of this study was to assess physical function and HRQOL of MPM patients following pleurectomy/decortication (P/D)...
March 14, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28287916/the-effect-of-contrast-medium-on-radiation-dose-in-ct-part-ii-a-systematic-evaluation-across-58-patient-models
#18
Pooyan Sahbaee, Ehsan Abadi, W Paul Segars, Daniele Marin, Rendon C Nelson, Ehsan Samei
Purpose To estimate the radiation dose as a result of contrast medium administration in a typical abdominal computed tomographic (CT) examination across a library of contrast material-enhanced computational patient models. Materials and Methods In part II of this study, first, the technique described in part I of this study was applied to enhance the extended cardiac-torso models with patient-specific iodine-time profiles reflecting the administration of contrast material. Second, the patient models were deployed to assess the patient-specific organ dose as a function of time in a typical abdominal CT examination using Monte Carlo simulation...
March 13, 2017: Radiology
https://www.readbyqxmd.com/read/28285656/relationships-of-insulin-like-growth-factor-1-its-binding-proteins-and-cardiometabolic-risk-in-hypertensive-perimenopausal-women
#19
Agnieszka Olszanecka, Aneta Dragan, Kalina Kawecka-Jaszcz, Danuta Fedak, Danuta Czarnecka
PURPOSE: During the transition from premenopause to postmenopause, many women experience weight gain and central fat deposition; therefore, we hypothesized that circulating growth factors can play a role in the pathogenesis of hypertension, metabolic syndrome, and subclinical organ damage in perimenopausal women. BASIC PROCEDURES: The study included 192 women aged 40 to 60years; 152 had newly diagnosed essential hypertension that had never been treated, and 40 were normotensive age-matched controls...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28280402/psychometric-properties-and-validation-of-the-italian-version-of-the-family-assessment-measure-third-edition-short-version-in-a-nonclinical-sample
#20
Monica Pellerone, Tiziana Ramaci, Santa Parrello, Paola Guariglia, Flavio Giaimo
BACKGROUND: Family functioning plays an important role in developing and maintaining dysfunctional behaviors, especially during adolescence. The lack of indicators of family functioning, as determinants of personal and interpersonal problems, represents an obstacle to the activities aimed at developing preventive and intervention strategies. The Process Model of Family Functioning provides a conceptual framework organizing and integrating various concepts into a comprehensive family assessment; this model underlines that through the process of task accomplishment, each family meets objectives central to its life as a group...
2017: Psychology Research and Behavior Management
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