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subjective organ function assessment

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https://www.readbyqxmd.com/read/29043698/gene-polymorphism-of-matrix-metalloproteinase-9-in-asthenozoospermic-male-subjects
#1
Sina Mohagheghi, Iraj Khodadadi, Manoochehr Karami, Iraj Amiri, Heidar Tavilani
Background: Matrix metalloproteinase (MMPs) play important roles in the structural and functional properties of reproductive organs. The aim of this study is to determine the prevalence of C-1562T MMP-9 (rs3918242) gene polymorphism in fertile and infertile men. In addition, we aim to determine the association between C-1562T MMP-9 and G-1575A MMP-2 gene polymorphisms. MATERIALS AND METHODS: A total of 400 subjects, including 200 fertile and 200 infertile men, were recruited for this casecontrol study...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29041938/development-of-breath-test-for-pneumoconiosis-a-case-control-study
#2
Hsiao-Yu Yang, Ruei-Hao Shie, Che-Jui Chang, Pau-Chung Chen
BACKGROUND: Lipid peroxidation plays an important role in the pathogenesis of pneumoconiosis. Volatile organic compounds (VOCs) generated from lipid peroxidation might be used to detect pneumoconiosis. The objective of this study was to develop a breath test for pneumoconiosis. METHODS: A case-control study was designed. Breath and ambient air were analysed by gas chromatography/mass spectrometry. After blank correction to prevent contamination from ambient air, we used canonical discriminant analysis (CDA) to assess the discrimination accuracy and principal component analysis (PCA) to generate a prediction score...
October 17, 2017: Respiratory Research
https://www.readbyqxmd.com/read/29030999/molecular-characterizations-of-dna-methyltransferase-3-and-its-roles-in-temperature-tolerance-in-the-whitefly-bemisia-tabaci-mediterranean
#3
T-M Dai, Z-C Lü, Y-S Wang, W-X Liu, X-Y Hong, F-H Wan
The Bemisia tabaci Mediterranean (MED) cryptic species is an invasive pest, distributed worldwide, with high ecological adaptability and thermotolerance. DNA methylation (a reversible chromatin modification) is one possible change that may occur within an organism subjected to environmental stress. To assess the effects of temperature stress on DNA methyltransferase 3 (Dnmt3) in MED, we cloned and sequenced BtDnmt3 and identified its functions in response to high and low temperatures. The full-length cDNA of BtDnmt3 was 3913 bp, with an open reading frame of 1962 bp, encoding a 73...
October 14, 2017: Insect Molecular Biology
https://www.readbyqxmd.com/read/29019365/blueberry-supplementation-attenuates-oxidative-stress-within-monocytes-and-modulates-immune-cell-levels-in-adults-with-metabolic-syndrome-a-randomized-double-blind-placebo-controlled-trial
#4
Anand R Nair, Nithya Mariappan, April J Stull, Joseph Francis
BACKGROUND: Blueberries (BB) have been shown to improve insulin sensitivity and endothelial function in obese and pre-diabetic humans, and decrease oxidative stress and inflammation, and ameliorate cardio-renal damage in rodents. This indicates that blueberries have a systemic effect and are not limited to a particular organ system. In order for blueberries to exert beneficial effects on the whole body, the mechanism would logically have to operate through modulation of cellular humoral factors...
October 11, 2017: Food & Function
https://www.readbyqxmd.com/read/28989049/individual-variability-of-the-human-cerebral-cortex-identified-using-intraoperative-mapping
#5
Johan Pallud, Marc Zanello, Grégory Kuchcinski, Alexandre Roux, Jun Muto, Charles Mellerio, Edouard Dezamis, Catherine Oppenheim
BACKGROUND: The intraoperative functional cortical mapping using direct electrical stimulation may show a wider individual variability than those suggested by non-invasive imaging data on healthy subjects. METHODS: We assessed the intraoperative variability of the frontal eye fields and of the speech arrest sites in adult patients having undergone a wide-awake craniotomy with direct electrostimulation for diffuse gliomas located within eloquent regions and we compared with the human cortical parcellation of the Human Connectome Project (Glasser, Nature, 2016)...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28988490/the-measurement-of-functioning-using-the-international-classification-of-functioning-disability-and-health-comparing-qualifier-ratings-with-existing-health-status-instruments
#6
Birgit Prodinger, Gerold Stucki, Michaela Coenen, Alan Tennant
BACKGROUND: The International Classification of Functioning, Disability and Health is the international standard for describing and monitoring functioning. While the categories, the units of the classification, were not designed with measurement in mind, the hierarchical structure of the classification lends itself to the possibility of summating categories into some higher order domain. Focusing on the chapters of d4 Mobility, d5 Self-Care and d6 Domestic Life, this study seeks to ascertain if qualifiers rating of categories (0-No problem to 4-Complete problem) within those chapters can be summated, and whether such derived measurement is consistent with estimates obtained from well-known instruments which purport to measure the same constructs...
October 8, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28988251/efficacy-and-safety-of-a-generic-rosuvastatin-in-a-real-world-setting-prospective-observational-clinical-study-in-lebanese-patients
#7
Mohamad Betto, Jocelyne Fares, Nada Saliba, Hajar Ballout
BACKGROUND: No published studies have assessed the efficacy and safety of rosuvastatin generics. OBJECTIVES: Primary objective to assess the safety and efficacy of a generic rosuvastatin in reducing plasma low-density-lipoprotein cholesterol (LDL-C) in Lebanese dyslipidemic patients. Changes in high-density lipoprotein cholesterol, triglycerides and adverse effects were secondary objectives. DESIGN: Prospective, observational, non-comparative...
September 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28971436/long-term-survival-of-women-with-breast-cancer-overview-supportive-care-needs-assessment-instruments
#8
Parthenopi Ktistaki, Nephely Alevra, Maria Voulgari
INTRODUCTION: Worldwide, breast cancer is the fifth leading cause of cancer death (after lung, stomach, liver and colon cancer), while among women it is first on the list. The incidence of breast cancer has made a dramatic increase since 1970 which is partly interpreted by the modern western life standards. The expected risk of breast cancer throughout a lifespan of an average is 1 in 11 women. The five-year survival rates for breast cancer are at 80% if it has not spread, and only at 40% for the metastatic type of cancer...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28968754/influences-on-the-test-retest-reliability-of-functional-connectivity-mri-and-its-relationship-with-behavioral-utility
#9
Stephanie Noble, Marisa N Spann, Fuyuze Tokoglu, Xilin Shen, R Todd Constable, Dustin Scheinost
Best practices are currently being developed for the acquisition and processing of resting-state magnetic resonance imaging data used to estimate brain functional organization-or "functional connectivity." Standards have been proposed based on test-retest reliability, but open questions remain. These include how amount of data per subject influences whole-brain reliability, the influence of increasing runs versus sessions, the spatial distribution of reliability, the reliability of multivariate methods, and, crucially, how reliability maps onto prediction of behavior...
September 12, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28964638/phonation-analysis-combined-with-3d-reconstruction-of-the-thyroarytenoid-muscle-in-aged-ovine-ex-vivo-larynx-models
#10
Claus Gerstenberger, Michael Döllinger, Stefan Kniesburges, Vladimir Bubalo, Michael Karbiener, Hansjörg Schlager, Hossein Sadeghi, Olaf Wendler, Markus Gugatschka
OBJECTIVE: The aim of the study was to establish a basic data set of combined functional and anatomical measures of aged sheep larynges using ex vivo models. Combining these two approaches in one and the same larynx is an unmet goal so far yet is important as newer treatment strategies aim to preserve the organ structure and new assessment tools are required. Ovine larynges were used as their dimensions, and muscle fiber type distribution highly resemble the human larynx. STUDY DESIGN: Ex vivo animal study...
September 27, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28957708/removal-of-the-veterinary-antimicrobial-sulfamethazine-in-a-horizontal-flow-anaerobic-immobilized-biomass-haib-reactor-subjected-to-step-changes-in-the-applied-organic-loading-rate
#11
G H D Oliveira, A J Santos-Neto, M Zaiat
A bench-scale horizontal-flow anaerobic immobilized biomass (HAIB) reactor treating synthetic swine wastewater was operated under different applied organic loading rates (OLR) through both variations in feed strength and in hydraulic retention time (HRT). The influence of step changes in OLR on the removal of the veterinary antimicrobial sulfamethazine (SMZ) was assessed. The highest observed SMZ removal efficiency, 75 ± 6%, was achieved with an OLR of 2.7 ± 0.4 kg O2 m(-3) d(-1) when a significant increase in COD removal rate was observed...
December 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28953613/surgical-management-of-female-pelvic-organ-prolapse-with-and-without-urinary-incontinence-a-single-center-experience
#12
Luigi Cormio, Vito Mancini, Giuseppe Liuzzi, Nicola d'Altilia, Giuseppe Carrieri
The study reports a single center experience with surgical management of female pelvic organ prolapse (POP) with and without urinary incontinence.Between January 2006 and July 2016, 93 consecutive patients with anterior and/or apical symptomatic POP underwent abdominal sacrocolpopexy (ASC) or laparoscopic sacrocolpopexy (LSC) or pubovaginal cystocele sling (PCS); 25 patients had concomitant stress urinary incontinence (SUI). Subjective outcome was assessed by the Pelvic Floor Impact Questionnaire (short form) (PFIQ-7) investigating bladder, bowel and vaginal functions, sexual activity, and daily life...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28950909/systemic-impact-on-secondary-brain-aggravation-due-to-ischemia-reperfusion-injury-in-post-cardiac-arrest-syndrome-a-prospective-observational-study-using-high-mobility-group-box-1-protein
#13
Atsunori Sugita, Kosaku Kinoshita, Atsushi Sakurai, Nobutaka Chiba, Junko Yamaguchi, Tsukasa Kuwana, Nami Sawada, Satoshi Hori
BACKGROUND: Ischemia/reperfusion injury (I/R) is an important pathophysiology of post-cardiac arrest syndrome (PCAS) against multiple organ dysfunction and mortality. The inflammatory response in PCAS causes systemic I/R. The purpose of this study was to demonstrate the pathophysiology of systemic I/R for secondary brain damage using the biomarkers high-mobility group box 1 (HMGB1), neuron-specific enolase (NSE), and interleukin-6 (IL-6). METHODS: This study was designed as a single-institution prospective observational study...
September 26, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28932370/clinical-evaluation-of-vasomotor-system-functionality-in-type-2-diabetic-patients
#14
Mehdi Maghbooli, Hossein Chiti, Sakineh Taheri, Masoud Asadi-Khiavi
BACKGROUND: Autonomic neuropathy and vital organ dysfunctions are the known complications in type 2 diabetes Mellitus (DM). Genetic endowments involving individuals make subtle differences in physiological systems, particularly at the time of sickness. Hence, the presented study was designed to evaluate the vasomotor system in healthy people and type 2 DM cases for determining any functionality differences between the mentioned groups. METHODS: Sixty patients with type 2 diabetes (case group) and sixty healthy subjects (control group) matched for age and sex were enrolled in the study...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28919825/abdominal-sacrocolpopexy-with-pelvicol-xenograft-and-concomitant-burch-colposuspension
#15
Sameh Hijazi, Dieter Echtle, Omar M Aboumarzouk, Elmar Heinrich
PURPOSE: To evaluate the efficacy of Pelvicol xenograft use during abdominal sacrocolpopexy to repair pelvic organ prolapse (POP). PATIENTS AND METHODS: A total of 27 consecutive women with symptomatic POP were included in this study. A POP-quantification system and International Continence Society classification were used. Functional and anatomical outcomes were assessed. Subjective outcomes and physical activity after surgery were evaluated due to modified quality of life questionnaire...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28912675/deceptive-but-not-honest-manipulative-actions-are-associated-with-increased-interaction-between-middle-and-inferior-frontal-gyri
#16
Maxim Kireev, Alexander Korotkov, Natalia Medvedeva, Ruslan Masharipov, Svyatoslav Medvedev
The prefrontal cortex is believed to be responsible for execution of deceptive behavior and its involvement is associated with greater cognitive efforts. It is also generally assumed that deception is associated with the inhibition of default honest actions. However, the precise neurophysiological mechanisms underlying this process remain largely unknown. The present study was aimed to use functional magnetic resonance imaging to reveal the underlying functional integration within the prefrontal cortex during the task which requires that subjects to deliberately mislead an opponent through the sequential execution of deceptive and honest claims...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28911273/memory-enhancement-of-fresh-ginseng-on-deficits-induced-by-chronic-restraint-stress-in-mice
#17
Liming Dong, Yi Wang, Jingwei Lv, Hongxia Zhang, Ning Jiang, Cong Lu, Pan Xu, Xinmin Liu
OBJECTIVES: Chronic stress exposure can disrupt the balance of organisms, result in learning and memory impairments and induce oxidative stress. However, there is a lack of safe and effective long-term therapeutic agents for stress-related injuries. Fresh ginseng (FG), an unprocessed raw root of ginseng, has antioxidant and neuroprotective activities and has been used as functional health food in Asian countries for many years. The aim of this study was to verify the protective effects of FG on chronic restraint stress (CRS)-induced learning and memory impairments as well as oxidative stress damage in mice...
September 15, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28910997/paediatric-nuclear-medicine-imaging
#18
Lorenzo Biassoni, Marina Easty
Background: Nuclear medicine imaging explores tissue viability and function by using radiotracers that are taken up at cellular level with different mechanism. This imaging technique can also be used to assess blood flow and transit through tubular organs. Nuclear medicine imaging has been used in paediatrics for decades and this field is continuously evolving. Sources of data: The data presented comes from clinical experience and some milestone papers on the subject...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28878462/effect-of-task-oriented-activities-on-hand-functions-cognitive-functions-and-self-expression-of-elderly-patients-with-dementia
#19
Bo-Young Son, Yo-Soon Bang, Min-Ji Hwang, Eun-Ju Oh
[Purpose] This study investigates the effects of task-oriented activities on hand function, cognitive function, and self-expression of the elderly with dementia, and then identify the influencing factors on self-expression in sub-factors of dependent variables. [Subjects and Methods] Forty elderly persons were divided into two groups: intervention group (n=20) and control group (n=20). The interventions were applied to the subjects 3 times a week, 50 minutes per each time, for a total of five weeks. We measured the jamar hand dynamometer test for grip strength, the jamar hydraulic pinch gauge test for prehension test, nine-hole pegboard test for coordination test, and Loewenstein Occupational Therapy Cognitive Assessment-Geriatric Population for cognitive function, and self-expression rating scale for self-expression test...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28871354/putting-pop-q-to-the-test-does-c%C3%A2-%C3%A2-d%C3%A2-%C3%A2-cervical-length
#20
Kathryn S Williams, Lisa Rosen, Marjorie L Pilkinton, Laura Dhariwal, Harvey A Winkler
INTRODUCTION AND HYPOTHESIS: We investigated the correlation between calculated cervical length (CCL) and gross specimen cervical length (GCL) after total vaginal hysterectomy (TVH) at the time of surgery for pelvic organ prolapse (POP). METHODS: This was a retrospective chart review of patients who had undergone TVH with reconstructive surgery for POP between 2013 and 2015. Patients without an intact specimen or documented cervical length in the pathology report were excluded...
September 4, 2017: International Urogynecology Journal
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