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subjective organ function assessment

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https://www.readbyqxmd.com/read/29209503/a-comparative-cross-sectional-study-of-some-hematological-parameters-of-hypertensive-and-normotensive-individuals-at-the-university-of-gondar-hospital-northwest-ethiopia
#1
Bamlaku Enawgaw, Nigist Adane, Betelihem Terefe, Fikir Asrie, Mulugeta Melku
Background: Hypertension is a major health problem worldwide. It can lead to cardiovascular disease and also leads to functional disturbances including hematological parameters. The abnormalities of haematological parameters may enhance an end-organ damage. Therefore, the aim of this study was to assess some hematological parameters of hypertensive individuals in comparison with normotensive individuals at University of Gondar hospital, northwest Ethiopia. Methods: A cross sectional comparative study was conducted from October to November 2015 on a total of 126 hypertensive and 126 normotensive individuals at University of Gondar Hospital...
2017: BMC Hematology
https://www.readbyqxmd.com/read/29197793/native-plant-amendments-and-topsoil-addition-enhance-soil-function-in-post-mining-arid-grasslands
#2
Tayla Kneller, Richard J Harris, Amber Bateman, Miriam Muñoz-Rojas
One of the most critical challenges faced in restoration of disturbed arid lands is the limited availability of topsoil. In post-mining restoration, alternative soil substrates such as mine waste could be an adequate growth media to alleviate the topsoil deficit, but these materials often lack appropriate soil characteristics to support the development and survival of seedlings. Thus, addition of exogenous organic matter may be essential to enhance plant survival and soil function. Here, we present a case study in the arid Pilbara region (north-west Western Australia), a resource-rich area subject to intensive mining activities...
November 30, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29196702/spatial-statistical-modelling-of-capillary-non-perfusion-in-the-retina
#3
Ian J C MacCormick, Yalin Zheng, Silvester Czanner, Yitian Zhao, Peter J Diggle, Simon P Harding, Gabriela Czanner
Manual grading of lesions in retinal images is relevant to clinical management and clinical trials, but it is time-consuming and expensive. Furthermore, it collects only limited information - such as lesion size or frequency. The spatial distribution of lesions is ignored, even though it may contribute to the overall clinical assessment of disease severity, and correspond to microvascular and physiological topography. Capillary non-perfusion (CNP) lesions are central to the pathogenesis of major causes of vision loss...
December 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29196484/effect-of-herbal-extract-granules-combined-with-otilonium-bromide-on-irritable-bowel-syndrome-with-diarrhoea-a-study-protocol-for-a-randomised-controlled-trial
#4
Joong Il Kim, Pumsoo Kim, Jin-Hyun Lee, Yoo-Jin Kim, Na-Rae Yang, Myong Ki Baeg, Ja Sung Choi, Hye-Jung Kim, Jayoung Kim, Yun-Young Sunwoo, Jung-Han Lee, Hyekyung Ha, Tae-Yong Park
INTRODUCTION: Irritable bowel syndrome (IBS), known as a functional and organic gastrointestinal disorder, is a collection of symptoms that occur together and generally include pain or discomfort in the abdomen and changes in bowel movement patterns. Due to the limitations of conventional treatments, alternative IBS treatments are used by many patients worldwide. Samryungbaekchulsan (SRS), a herbal formula, has long been used for alleviating diarrhoea-predominant IBS (D-IBS) in traditional Korean medicine...
December 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/29193423/assessing-body-awareness-and-autonomic-reactivity-factor-structure-and-psychometric-properties-of-the-body-perception-questionnaire-short-form-bpq-sf
#5
Ana Cabrera, Jacek Kolacz, Guillem Pailhez, Andrea Bulbena-Cabre, Antonio Bulbena, Stephen W Porges
Body awareness and reactivity dysfunction are characteristic of a range of psychiatric disorders. Although the neural pathways communicating between the body and brain that contribute to these experiences involve the autonomic nervous system, few research tools for studying subjective bodily experiences have been informed by these neural circuits. This paper describes the factor structure, reliability, and convergent validity of the Body Awareness and Autonomic Reactivity subscales of the Body Perception Questionnaire-Short Form (BPQ-SF)...
November 28, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/29193065/stereological-assessment-of-the-blood-air-barrier-and-the-surfactant-system-after-mesenchymal-stem-cell-pretreatment-in-a-porcine-non-heart-beating-donor-model-for-lung-transplantation
#6
Anke Schnapper, Astrid Christmann, Lars Knudsen, Parwis Rahmanian, Yeong-Hoon Choi, Mohamed Zeriouh, Samira Karavidic, Klaus Neef, Anja Sterner-Kock, Maria Guschlbauer, Florian Hofmaier, Alexandra C Maul, Thorsten Wittwer, Thorsten Wahlers, Christian Mühlfeld, Matthias Ochs
More frequent utilization of non-heart-beating donor (NHBD) organs for lung transplantation has the potential to relieve the shortage of donor organs. In particular with respect to uncontrolled NHBD, concerns exist regarding the risk of ischaemia/reperfusion (IR) injury-related graft damage or dysfunction. Due to their immunomodulating and tissue-remodelling properties, bone-marrow-derived mesenchymal stem cells (MSCs) have been suspected of playing a beneficial role regarding short- and long-term survival and function of the allograft...
November 28, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/29191225/landscape-and-evolution-of-tissue-specific-alternative-polyadenylation-across-drosophila-species
#7
Piero Sanfilippo, Jiayu Wen, Eric C Lai
BACKGROUND: Drosophila melanogaster has one of best-described transcriptomes of any multicellular organism. Nevertheless, the paucity of 3'-sequencing data in this species precludes comprehensive assessment of alternative polyadenylation (APA), which is subject to broad tissue-specific control. RESULTS: Here, we generate deep 3'-sequencing data from 23 developmental stages, tissues, and cell lines of D. melanogaster, yielding a comprehensive atlas of ~ 62,000 polyadenylated ends...
November 30, 2017: Genome Biology
https://www.readbyqxmd.com/read/29191171/self-assessment-of-the-mental-health-status-in-older-adults-in-poland-a-cross-sectional-study
#8
Mateusz Cybulski, Lukasz Cybulski, Elzbieta Krajewska-Kulak, Urszula Cwalina
BACKGROUND: Demographic aging of society poses numerous challenges, including the provision of health care to the elderly population. According to World Health Organization data, the most frequent mental disorders in the senior population are: dementia, depression, and drug and alcohol addiction. The aim of this study was to subjectively assess mental health status (the severity of non-psychotic symptoms of mental functions and depressive symptoms) in older adults of Bialystok (Poland)...
December 1, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29187794/reliability-of-ckd-epi-predictive-equation-in-estimating-chronic-kidney-disease-prevalence-in-the-croatian-endemic-nephropathy-area
#9
Mirjana Fuček, Živka Dika, Sandra Karanović, Ivana Vuković Brinar, Vedran Premužić, Jelena Kos, Ante Cvitković, Maja Mišić, Josip Samardžić, Dunja Rogić, Bojan Jelaković
Introduction: Chronic kidney disease (CKD) is a significant public health problem and it is not possible to precisely predict its progression to terminal renal failure. According to current guidelines, CKD stages are classified based on the estimated glomerular filtration rate (eGFR) and albuminuria. Aims of this study were to determine the reliability of predictive equation in estimation of CKD prevalence in Croatian areas with endemic nephropathy (EN), compare the results with non-endemic areas, and to determine if the prevalence of CKD stages 3-5 was increased in subjects with EN...
February 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/29182088/perinatal-maternal-mortality-in-sickle-cell-anemia-two-case-reports-and-review-of-the-literature
#10
Sanaa Rizk, Elizabeth D Pulte, David Axelrod, Samir K Ballas
As outcomes of patients with sickle cell anemia improve and survival into adulthood with good quality of life and expectation of long-term survival becomes more common, challenges have developed, including issues related to reproduction. Pregnancy is frequently complicated in patients with sickle cell anemia with mortality up to 4.0%. Here we report maternal perinatal mortality in two women with sickle cell anemia who died post-partum due to acute chest syndrome (ACS), caused by bone marrow fat embolism and review the literature pertinent to this subject...
November 28, 2017: Hemoglobin
https://www.readbyqxmd.com/read/29177906/experimental-study-of-statistical-stability-of-cardiointerval-samples
#11
V G Zilov, A A Khadartsev, V V Eskov, V M Eskov
In 1947 M. A. Bernstein proposed a hypothesis about "repetition without repetition" in biomechanics that was confirmed in psychophysiology by the Eskov-Zinchenko effect. This effect can be applied to all parameters (except the parameters of the neuromuscular system) of human body homeostasis. For instance, this instability can be demonstrated for repeated samples of cardiointerval parameters (and other homeostasis parameters) of the human cardiorespiratory system. Within the framework of the new theory of chaos and self-organization, a method is proposed for calculation of matrices of paired comparisons of cardiointerval samples for assessing the physiological status of the human body and changes in homeostasis...
November 25, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29175291/testing-competing-models-of-injunctive-and-descriptive-norms-for-proximal-and-distal-reference-groups-on-alcohol-attitudes-and-behavior
#12
Andrew Lac, Candice D Donaldson
INTRODUCTION: Injunctive norms represent perceptions regarding the extent that others approve of a behavior, whereas descriptive norms represent perceptions of the extent that others engage in a behavior. This study evaluated competing path models, varying in the representation of injunctive and descriptive norm constructs, to forecast alcohol attitudes and use. METHODS: College students (N=326) answered questions about their normative perceptions regarding three relevant reference groups (typical students, friends, and parents) in the form of alcohol injunctive and descriptive norms...
November 14, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29172879/circadian-rhythms-in-visual-responsiveness-in-the-behaviorally-arrhythmic-drosophila-clock-mutant-clkjrk
#13
Olivia M Nippe, Alex R Wade, Christopher J H Elliott, Sangeeta Chawla
An organism's biological day is characterized by a pattern of anticipatory physiological and behavioral changes that are governed by circadian clocks to align with the 24-h cycling environment. Here, we used flash electroretinograms (ERGs) and steady-state visually evoked potentials (SSVEPs) to examine how visual responsiveness in wild-type Drosophila melanogaster and the circadian clock mutant ClkJrk varies over circadian time. We show that the ERG parameters of wild-type flies vary over the circadian day, with a higher luminance response during the subjective night...
November 1, 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29171842/-assessment-of-work-environment-vs-feeling-of-threat-and-aggravation-of-stress-in-job-of-a-high-risk-an-attempt-of-organizational-intervention
#14
Marta Stasiła-Sieradzka, Agata Chudzicka-Czupała, Damian Grabowski, Małgorzata Dobrowolska
BACKGROUND: The main purpose of this article was to examine, whether and to what extend an assessment of work environment and feeling of threat are associated with stress at work performed in health- and life-threatening conditions. Previous studies of the determinants of occupational stress have been carried out in relation to representatives of different occupational groups that are not, however, representatives of one organization. The research was also meant to provide practical guidance for a particular employer...
November 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/29164117/active-aging-in-very-old-age-and-the-relevance-of-psychological-aspects
#15
Constança Paúl, Laetitia Teixeira, Oscar Ribeiro
Background: Active aging encompasses a socially and individually designed mix of different domains that range from personal and familial, to social and professional. In being a key policy concept often focused on the young-old individuals, efforts in studying its dimensions in advanced ages have seldom been made. Nevertheless, there is a recognized need to promote adequate responses to the growing number of individuals reaching advanced ages and to recognize their specific dependability on health-related aspects, services attendance, social interactions, or on psychological characteristics for what it means to "age actively...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29162614/discovery-and-validation-of-pyridoxic-acid-and-homovanillic-acid-as-novel-endogenous-plasma-biomarkers-of-organic-anion-transporter-oat-1-and-oat3-in-cynomolgus-monkeys
#16
Hong Shen, David M Nelson, Regina V Oliveira, Yueping Zhang, Colleen A Mcnaney, Xiaomei Gu, Weiqi Chen, Ching Su, Michael D Reily, Petia A Shipkova, Jinping Gan, Yurong Lai, Punit Marathe, W Griffith Humphreys
Perturbation of OAT1- and OAT3-mediated transport can alter the exposure, efficacy, and safety of drugs. Although these have been reports of the endogenous biomarkers for OAT1/3, none of these have all of the characteristics required for a clinical useful biomarker. Cynomolgus monkeys were treated with intravenous probenecid (PROB) at a dose of 40 mg/kg in this study. As expected, PROB increased the AUC of co-administered furosemide (FSM), a known substrate of OAT1 and OAT3, by 4.1-fold, consistent with the values reported in humans (3...
November 21, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29161295/cardiac-and-renal-dysfunction-is-associated-with-progressive-hearing-loss-in-patients-with-fabry-disease
#17
Maria Köping, Wafaa Shehata-Dieler, Mario Cebulla, Kristen Rak, Daniel Oder, Jonas Müntze, Peter Nordbeck, Christoph Wanner, Rudolf Hagen, Sebastian Schraven
BACKGROUND: Fabry disease (FD) is an X-linked recessive hereditary lysosomal storage disorder which results in the accumulation of globotriaosylceramid (Gb3) in tissues of kidney and heart as well as central and peripheral nervous system. Besides prominent renal and cardiac organ involvement, cochlear symptoms like high-frequency hearing loss and tinnitus are frequently found with yet no comprehensive data available in the literature. OBJECTIVE: To examine hearing loss in patients with FD depending on cardiac and renal function...
2017: PloS One
https://www.readbyqxmd.com/read/29159665/functional-rostro-caudal-gradient-in-the-human-posterior-lateral-frontal-cortex
#18
Céline Amiez, Michael Petrides
The present study examined the hypothesis that the posterior motor/premotor region of the lateral frontal cortex is functionally organized along a rostro-caudal axis. During functional magnetic resonance imaging scanning, the subjects performed various tasks assessing basic saccadic eye or hand actions and also tasks requiring the cognitive selection between competing hand or eye movements based on previously learned conditional relations (if A, select movement X, but if B select movement Y). Subject-by-subject analysis demonstrated precise relationships between the foci of functional activity and specific sulci...
November 20, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29155552/reliably-modeling-the-mechanical-stability-of-rigid-and-flexible-metal-organic-frameworks
#19
Sven M J Rogge, Michel Waroquier, Veronique Van Speybroeck
Over the past two decades, metal-organic frameworks (MOFs) have matured from interesting academic peculiarities toward a continuously expanding class of hybrid, nanoporous materials tuned for targeted technological applications such as gas storage and heterogeneous catalysis. These oft-times crystalline materials, composed of inorganic moieties interconnected by organic ligands, can be endowed with desired structural and chemical features by judiciously functionalizing or substituting these building blocks...
November 20, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29150155/the-association-of-functional-capacity-with-right-atrial-deformation-in-patients-with-pulmonary-arterial-hypertension-a-study-with-two-dimensional-speckle-tracking
#20
Weiwei Liu, Yueheng Wang, Jinling Zhou, Hui Bai, Feng Wang, Ju Wang
BACKGROUND: The purpose of this study was to assess right atrial (RA) myocardial mechanics in pulmonary hypertension (PH) patients using two-dimensional speckle tracking (2D-STE), and define the relationship between RA function and exercise capacity in PH patients. METHODS: Thirty-eight consecutive PH patients were studied and compared with a control group of 25 healthy volunteers. Peak atrial longitudinal strain (PALS), RA strain rate were measured in all subjects...
April 13, 2017: Heart, Lung & Circulation
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