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Head and Neck AND cancer AND nutrition

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https://www.readbyqxmd.com/read/27875286/new-immunomodulatory-oral-nutrition-formula-for-use-prior-to-surgery-in-patients-with-head-and-neck-cancer-an-exploratory-study
#1
Samara Palma-Milla, Bricia López-Plaza, Beatriz Santamaría, Álvaro de Arriba-Sánchez, Laura M Bermejo, Carmen Gómez-Candela
BACKGROUND: The perioperative use of immunomodulatory nutrition formulas in patients with head and neck cancer reduces the number of postoperative infections and the length of hospital stay. OBJECTIVE: An exploratory, randomized, controlled, blind, clinical trial was designed to examine the effect of the preoperative consumption of a new, immunomodulatory, oral nutrition formula in patients with head and neck cancer. METHODS: Thirty-eight patients were randomized to receive either 400 mL/d of either the new immunomodulatory formula (IF) or that commonly used in clinical practice (CF) over 10 days prior to surgery...
November 10, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27875280/malnutrition-identified-by-the-academy-of-nutrition-and-dietetics-and-american-society-for-parenteral-and-enteral-nutrition-consensus-criteria-and-other-bedside-tools-is-highly-prevalent-in-a-sample-of-individuals-undergoing-treatment-for-head-and-neck-cancer
#2
Urvashi Mulasi, David M Vock, Adam J Kuchnia, Gautam Jha, Naomi Fujioka, Venkatesh Rudrapatna, Manish R Patel, Levi Teigen, Carrie P Earthman
BACKGROUND: Using the Academy of Nutrition and Dietetics and American Society for Parenteral and Enteral Nutrition (Academy/ASPEN) Consensus malnutrition definition, we estimated malnutrition prevalence in a sample of individuals with head and neck cancer (HNC) and compared it with the Patient-Generated Subjective Global Assessment (PG-SGA). We also investigated the utility of the 50-kHz phase angle (PA) and 200-kHz/5-kHz impedance ratio (IR) to identify malnutrition. MATERIALS AND METHODS: Nineteen individuals (18 males, 1 female) scheduled to undergo chemoradiotherapy were seen at 5 time points during and up to 3 months after treatment completion...
October 7, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27865369/feasibility-of-using-head-and-neck-ct-imaging-to-assess-skeletal-muscle-mass-in-head-and-neck-cancer-patients
#3
Justin E Swartz, Ajit J Pothen, Inge Wegner, Ernst J Smid, Karin M A Swart, Remco de Bree, Loek P H Leenen, Wilko Grolman
OBJECTIVES: Patients with head and neck cancer (HNC) have a higher risk of malnutrition and sarcopenia, which is associated with adverse clinical outcome. As abdominal CT-imaging is often used to detect sarcopenia, such scans are rarely available in HNC patients, possibly explaining why no studies investigate the effect of sarcopenia in this population. We correlated skeletal muscle mass assessed on head and neck CT-scans with abdominal CT-imaging. METHODS: Head and neck, and abdominal CT-scans of trauma (n=51) and HNC-patients (n=52) were retrospectively analyzed...
November 2016: Oral Oncology
https://www.readbyqxmd.com/read/27847115/pre-therapeutic-nutritional-assessment-for-predicting-severe-adverse-events-in-patients-with-head-and-neck-cancer-treated-by-radiotherapy
#4
Takeyuki Kono, Koji Sakamoto, Seiichi Shinden, Kaoru Ogawa
BACKGROUND & AIMS: Malnutrition is common in patients with head and neck cancer (HNSCC). It may be related to severe adverse toxicity as a result of radiotherapy. The aim was to investigate nutritional screening factors for severe adverse events. METHODS: A retrospective chart review of 101 patients who underwent radiotherapy from 2009 to 2013 was performed. The relationships among severe adverse events and pretreatment nutritional parameters, including static variables (serum albumin, total protein, total lymphocyte counts, body mass index), dynamic variables (retinol-binding protein, transferrin, pre-albumin), and nutritional screening tools (Onodera's Prognostic Nutrition Index [O-PNI]; Nutrition Risk Index; Controlling Nutritional Status [CONUT] score; Nutritional Risk Screening 2002) were evaluated in addition to patient and treatment factors...
November 5, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27812016/circulating-vitamin-d-in-relation-to-cancer-incidence-and-survival-of-the-head-and-neck-and-oesophagus-in-the-epic-cohort
#5
Anouar Fanidi, David C Muller, Øivind Midttun, Per Magne Ueland, Stein Emil Vollset, Caroline Relton, Paolo Vineis, Elisabete Weiderpass, Guri Skeie, Magritt Brustad, Domenico Palli, Rosario Tumino, Sara Grioni, Carlotta Sacerdote, H B As Bueno-de-Mesquita, Petra H Peeters, Marie-Christine Boutron-Ruault, Marina Kvaskoff, Claire Cadeau, José María Huerta, Maria-José Sánchez, Antonio Agudo, Cristina Lasheras, J Ramón Quirós, Saioa Chamosa, Elio Riboli, Ruth C Travis, Heather Ward, Neil Murphy, Kay-Tee Khaw, Antonia Trichopoulou, Pagona Lagiou, Eleni-Maria Papatesta, Heiner Boeing, Tilman Kuehn, Verena Katzke, Annika Steffen, Anders Johansson, Paul Brennan, Mattias Johansson
Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs of the head and neck and oesophagus, as well as 443 additional controls. Circulating 25(OH)D3 were measured in pre-diagnostic samples and evaluated in relation to HNC and oesophagus cancer risk and post-diagnosis all-cause mortality...
November 4, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27803609/bioelectrical-impedance-phase-angle-as-a-prognostic-indicator-of-survival-in-head-and-neck-cancer
#6
M S Władysiuk, R Mlak, K Morshed, W Surtel, A Brzozowska, T Małecka-Massalska
BACKGROUND: Phase angle could be an alternative to subjective global assessment for the assessment of nutrition status in patients with head-and-neck cancer. METHODS: We prospectively evaluated a cohort of 75 stage iiib and iv head-and-neck patients treated at the Otolaryngology Department, Head and Neck Surgery, Medical University of Lublin, Poland. Bioelectrical impedance analysis was performed in all patients using an analyzer that operated at 50 kHz. The phase angle was calculated as reactance divided by resistance (Xc/R) and expressed in degrees...
October 2016: Current Oncology
https://www.readbyqxmd.com/read/27765549/factors-influencing-postoperative-complications-in-reconstructive-microsurgery-for-head-and-neck-cancer
#7
Shih-Lun Lo, Yu-Hsiu Yen, Pi-Jung Lee, Charles Chih-Ho Liu, Chi-Ming Pu
PURPOSE: The present study aimed to analyze multiple variables and to determine the factors influencing postoperative complications in reconstructive microsurgeries for head and neck cancer. MATERIALS AND METHODS: This was a retrospective review of the medical records of patients with head and neck cancer who underwent free flap reconstruction after ablation surgery at the Cathay General Hospital (Taipei, Taiwan) from January 2010 to December 2014. Clinical and surgical procedure-related factors were retrieved from a database and analyzed...
September 23, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27734748/cost-analysis-of-cetuximab-erbitux-plus-radiotherapy-ert-versus-concomitant-cisplatin-plus-radiotherapy-crt-within-an-nhs-oncology-unit-single-institution-a-pilot-study
#8
Brammer Caroline, Yahya Sundus, Dawson Dawn, Glaister Carol, Merrick Susan
OBJECTIVE: The aim of this feasibility study is to define the resource effectiveness of cetuximab vs cisplatin given concomitantly with radiotherapy for squamous cell carcinoma within a National Health Service clinical oncology unit. METHODS: 20 patients with Stage 3 or 4 head and neck squamous cell cancers were randomized to receive either cetuximab with radiotherapy (ERT) or cisplatin with radiotherapy concurrent with external beam radiotherapy 70 Gy in 35 fractions on a 1 : 1 basis over a 12-month duration...
December 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27677662/quality-of-life-and-functional-status-of-terminally-ill-head-and-neck-cancer-patients-a-nation-wide-prospective-observational-study-at-tertiary-cancer-centers-in-japan
#9
Takeshi Shinozaki, Mitsuru Ebihara, Satoru Iwase, Takuhiro Yamaguchi, Hitoshi Hirakawa, Wataru Shimbashi, Tomoyuki Kamijo, Makito Okamoto, Takeshi Beppu, Junichiro Ohori, Kazuto Matsuura, Motoyuki Suzuki, Hiroshi Nishino, Yuichiro Sato, Hiroto Ishiki
BACKGROUND: Little is known about quality of life and functional status of patients with terminally ill head and neck cancers. METHODS: We conducted a multicenter, prospective, observational study to examine quality of life and functional status in terminally ill head and neck cancer patients. RESULTS: Of the 100 patients meeting inclusion criteria, 72 were observed until death. There was no significant difference in the quality of life score between baseline and Week 3...
September 27, 2016: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27635865/artificial-nutrition-dependence-after-cetuximab-versus-cisplatin-combined-with-radiotherapy-for-advanced-head-and-neck-cancer-a-propensity-score-matched-analysis
#10
Miho Ishimaru, Sachiko Ono, Sayaka Suzuki, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
BACKGROUND: The purpose of this study was to compare the effect of cetuximab-based radiotherapy (RT) with cisplatin-based concomitant chemoradiotherapy (CCRT) on artificial nutrition dependence in locoregional advanced head and neck cancer. METHODS: We identified patients treated with cetuximab-based RT or CCRT between 2012 and 2014 in a Japanese national database, and used propensity score-matched analyses to evaluate artificial nutrition dependence for 30 days after starting chemotherapy and at hospital discharge...
September 16, 2016: Head & Neck
https://www.readbyqxmd.com/read/27595312/dose-volume-analysis-of-radiation-induced-trismus-in-head-and-neck-cancer-patients
#11
Maria Gebre-Medhin, Mahnaz Haghanegi, Lotta Robért, Elisabeth Kjellén, Per Nilsson
INTRODUCTION: Trismus is a treatment-related late side effect in patients treated for cancer in the head and neck region (HNC). The condition can have a considerable negative impact on nutrition, dental hygiene, ability to speak and quality of life. We have previously studied trismus within the frame of a randomized phase 3 study of HNC patients treated with mainly three-dimensional (3D) conformal radiotherapy (CRT) and found a strong association to mean radiation dose to the mastication muscles, especially the ipsilateral masseter muscle (iMAS)...
November 2016: Acta Oncologica
https://www.readbyqxmd.com/read/27588193/effects-of-nutritional-intervention-in-head-and-neck-cancer-patients-undergoing-radiotherapy-a-prospective-randomized-clinical-trial
#12
Wen-Xing Kang, Wentao Li, Shi-Gao Huang, Yazhang Dang, Hongxiang Gao
Head and neck malignant tumors have numerous locations of the disease. After patients receive radiotherapy, their nutritional status is very poor, thus the curative effect is unsatisfactory. The aims of the present study were to investigate and analyze the nutritional status of patients with head and neck cancer undergoing radiotherapy (RT) in order to provide positive nutrition intervention for assisting the radiotherapy effect. A total of 40 patients with head and neck cancer were selected using a method of subjective global assessment (SGA) to assess nutritional status, including calorie intake and energy expenditure...
September 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27568350/intensive-nutritional-care-for-patients-treated-with-radiotherapy-in-head-and-neck-cancer-a-randomized-study-and-meta-analysis
#13
Lise-Marie Roussel, Emmanuel Micault, Damien Peyronnet, David Blanchard, Séverine Guarnieri, Olivier Choussy, Bernard Géry, Arnaud Béquignon, Corinne Joubert, Jean-Jacques Parienti, Emmanuel Babin
Nutritional care improves quality of life (QOL) in head and neck cancer patients treated with radiotherapy. The aim of our study was to determine whether intensive nutritional care (INC) would further improve QOL. In addition to a control group based on European and American guidelines, patients included in the INC group received six meetings with a dietitian. QOL was measured after radiotherapy using the EORTC QLQ-C30. We performed a meta-analysis to determine the best nutritional care. In the 87 patients, the QOL scores, weight, energy, and protein intakes were similar between the INC group (n = 43) and the control group (n = 44)...
August 27, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27551409/towards-a-pain-free-hospital-an-in-depth-qualitative-analysis-of-the-pain-experiences-of-head-and-neck-cancer-patients-undergoing-radiotherapy
#14
Natalie Pattison, Matthew Rd Brown, Anthony Gubbay, Janet Peacock, Joy R Ross, Suzanne Chapman, Odile Sauzet, John Williams
BACKGROUND: Treatment for head and neck cancer can frequently be a painful experience with implications for patients in terms of quality of life, nutrition and ultimately treatment outcomes. Pain may arise for a number of reasons in this patient group including the influence of localised tissue damage from radiotherapy, the effects of chemotherapeutic agents as well as the disease process itself. Early identification of cancer pain, through screening and early analgesic and pain management are thought to be the most appropriate approaches to the problem...
February 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27524909/the-effect-of-clove-based-herbal-mouthwash-on-radiation-induced-oral-mucositis-in-patients-with-head-and-neck-cancer-a-single-blind-randomized-preliminary-study
#15
Moonkyoo Kong, Deok-Sang Hwang, Seong Woo Yoon, Jinsung Kim
PURPOSE: This study was performed to evaluate the efficacy and safety of clove-based herbal mouthwash in ameliorating radiation-induced oral mucositis in patients with head and neck cancer. METHODS: Fourteen patients were prospectively enrolled in this study and randomized to either an experimental group or a control group. The patients of the experimental group swished their mouths with a clove-based herbal mouthwash during radiotherapy (RT), while the patients of the control group swished with clear water...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27512573/the-provision-of-enteral-nutritional-support-during-definitive-chemoradiotherapy-in-head-and-neck-cancer-patients
#16
REVIEW
Sarah Bishop, Warren Michael Reed
Combination chemoradiation is the gold standard of management for locally advanced squamous cell carcinomas of the head and neck. One of the most significant advantages of this approach to treatment is organ preservation which may not be possible with radical surgery. Unfortunately, few treatments are without side-effects and the toxicity associated with combined modality treatment causes meaningful morbidity. Patients with head and neck cancer (HNC) may have difficulties meeting their nutritional requirements as a consequence of tumour location or size or because of the acute toxicity associated with treatment...
December 2015: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/27505401/peg-insertion-in-patients-with-dementia-does-not-improve-nutritional-status-and-has-worse-outcomes-as-compared-with-peg-insertion-for-other-indications
#17
Ayman Abu R, Tawfik Khoury, Jonah Cohen, Shmuel Chen, Shaul Yaari, Saleh Daher, Ariel A Benson, Meir Mizrahi
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) tubes are commonly utilized as a method of enteral feeding in patients unable to obtain adequate oral nutrition. Although some studies have shown improved mortality in select populations, the safety and effectiveness of PEG insertion in patients with dementia compared with those with other neurological diseases or head and neck malignancy remains less well defined. OBJECTIVE: To evaluate the nutritional effectiveness, rate of rehospitalization, and risk of mortality among patients with dementia compared with patients with other neurological diseases or head and neck cancers who undergo PEG placement...
August 8, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27456260/-detection-and-evaluation-of-malnutrition-in-oncology-what-tools-what-type-of-cancer-and-for-what-purposes
#18
REVIEW
Sylvie Khan, Taher Arif Alibay, Mansouria Merad, Mario DiPalma, Bruno Raynard, Sami Antoun
Malnutrition is frequently observed in oncology. The consequences on patient survival, chemotherapy toxicities and quality of life need to be identified and treated appropriately. A set of tools are available that enable clinicians to diagnose and detect malnutrition. Each tool must consider three items: the patient's current nutritional status, reduced food intake and the characteristics of the underlying disease. The parameters and thresholds used to detect malnutrition differ according to the objective pursued...
September 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27433937/high-hospitalization-rates-in-survivors-of-childhood-cancer-a-longitudinal-follow-up-study-using-medical-record-linkage
#19
Elske Sieswerda, Anna Font-Gonzalez, Johannes B Reitsma, Marcel G W Dijkgraaf, Richard C Heinen, Monique W Jaspers, Helena J van der Pal, Flora E van Leeuwen, Huib N Caron, Ronald B Geskus, Leontien C Kremer
Hospitalization rates over time of childhood cancer survivors (CCS) provide insight into the burden of unfavorable health conditions on CCS and health care resources. The objective of our study was to examine trends in hospitalizations of CCS and risk factors in comparison with the general population. We performed a medical record linkage study of a cohort of 1564 ≥five-year CCS with national registers. We obtained a random sample of the general population matched on year of birth, gender and calendar year per CCS retrieved...
2016: PloS One
https://www.readbyqxmd.com/read/27424150/adipose-mesenchymal-stromal-cells-minimize-and-repair-radiation-induced-oral-mucositis
#20
Osama Muhammad Maria, Mostafa Shalaby, Alasdair Syme, Nicoletta Eliopoulos, Thierry Muanza
BACKGROUND AIMS: Mesenchymal stromal cells (MSCs) have been used to minimize and repair radiation-induced normal tissue injury in the intestine, salivary gland, liver, skin, lungs and cardiac muscle. This study investigated the ability of adipose tissue-derived MSCs (aMSCs) to minimize and/or repair single dose radiation-induced oral mucositis (RIOM). METHODS: Syngenic phenotypically and functionally characterized BALB/c mouse aMSCs were implanted intraperitoneally in a RIOM mouse model with different dosing protocols...
September 2016: Cytotherapy
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