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Depression plant extract

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https://www.readbyqxmd.com/read/27908257/ginkgo-biloba-as-an-alternative-medicine-in-the-treatment-of-anxiety-in-dementia-and-other-psychiatric-disorders
#1
Sandeep Kumar Singh, George E Barreto, Gjumrakch Aliev, Valentina Echeverria
BACKGROUND: Mental disorders are the most common health problems in the worldwide population. Current medicines against these conditions have undesired side effects or limited effectiveness. These disadvantageous pharmacological and therapeutic characteristics provoke a low adherence to treatment in an important percentage of patients with mental disorders. Since ancient times, ethnically different groups have been using plants extracts as medicines for the treatment of mental conditions including dementia, depression and anxiety disorders...
December 1, 2016: Current Drug Metabolism
https://www.readbyqxmd.com/read/27769218/in-vivo-sedative-activity-of-methanolic-extract-of-stericulia-villosa-roxb-leaves
#2
Md Forhad Hossain, Bashudeb Talukder, Mohammad Nasiruddin Rana, Refat Tasnim, Tanzina Sharmin Nipun, S M Naim Uddin, S M Moazzem Hossen
BACKGROUND: This plant is very popular ingredient of local made drinks during hot summer. After drinking this drink people feels fresh, relaxed and can enjoy sound sleep. Present study was aimed to assess the sedative properties of a plant Sterculia villosa leaves. Therefore, we tried to find out the methanolic extract from the leaves of Sterculia villosa leaves having any sedative activity or not. METHODS: The extract were subjected to various in vivo methods like hole cross test, open field test, elevated plus-maze (EPM) test, thiopental sodium induced sleeping time test...
October 21, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27765361/aralia-elata-var-mandshurica-rupr-maxim-j-wen-an-overview-of-pharmacological-studies
#3
Alexander N Shikov, Olga N Pozharitskaya, Valery G Makarov
PURPOSE: Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen syn. A. mandshurica Rupr. & Maxim is evaluated for its medicinal application. The aim of this study is to analyze pharmacological studies on A. elata var. mandshurica published until December 2015. METHODS: The information regarding the chemistry, safety, effectiveness, and pharmacological and clinical effects of A. elata was systematically collected from the scientific literature through library catalogs; online services such as E-library...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27761214/antidepressant-activity-of-enicostemma-littorale-blume-in-shp2-protein-tyrosine-phosphatase-inhibited-animal-model-of-depression
#4
V A Doss, Dharaniyambigai Kuberapandian
BACKGROUND: The objective of this study is to develop a new animal model based on signaling pathways to understand the pathophysiology, therapy of depression, and to investigate the antidepressant activity of Enicostemma littorale which is not yet established. METHODS: Animal models of depression were raised by physical methods and administration of methyl isobutyl ketone (100 mg/kg b.w., i.p.,) and a protein tyrosine phosphatase inhibitor, sodium orthovanadate (30 mg/kg b...
2016: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/27731836/review-glycyrrhiza-glabra-l-liquorice
#5
Ghulam Dastagir, Muhammad Afzal Rizvi
Medicinal plants are being used for treating various diseases. According to World Health Organization 80% of the world population depends on indigenous medicinal plant remedies. Herbal medicine employs fruits, vegetables, as dry materials or their extracts for the treatment of different diseases and health maintenance. Glycyrrhiza glabra (Liquorice) has been used in Europe since prehistoric times. It is well documented in written form starting with the ancient Greeks. Glycyrrhizin is the major active constituent obtained from liquorice roots, one of the most widely used in herbal preparations for the treatment of liver complaints...
September 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27731825/anxiolytic-and-antidepressant-activity-of-different-methanolic-extracts-of-melia-azedarach-linn
#6
Humera Ishaq
Present study was planned to search for neuropharmacological properties of methanolic extracts of different parts of Melia azedarach Linn. because conventional medicine shows adverse effects. Recently natural products are studied worldwide, as safer alternatives, which are not duly supported with scientifically proved data. Melia azedarach (Bakayan, China berry tree) is medium sized tree belonging to family Meliaceae. Traditional use of plant is as anthelmintic, antilithic and diuretic. Topical application of oil for cramps and rheumatism is beneficial...
September 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27720849/beneficial-effect-of-commercial-rhodiolaextract-in-rats-with-scopolamine-induced-memory-impairment-on-active-avoidance
#7
Liliya V Vasileva, Damianka P Getova, Nina D Doncheva, Andrey S Marchev, Milen I Georgiev
: Rhodiola rosea L., family Crassulaceae also known as Golden Root or Arctic root is one of the most widely used medicinal plants with effect on cognitive dysfunction, psychological stress and depression. The aim of the study was to examine the effect of a standardized commercial Rhodiola extract on learning and memory processes in naive rats as well as its effects in rats with scopolamine-induced memory impairment. MATERIALS AND METHODS: Sixty male Wistar rats were used in the study...
October 5, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27695263/effect-of-musa-sapientum-stem-extract-on-animal-models-of-depression
#8
Aditya J Reddy, Shailendra S Handu, Ashok Kumar Dubey, Pramod Kumari Mediratta, Rimi Shukla, Qazi Mushtaq Ahmed
BACKGROUND: Musa sapientum, the banana plant, has shown to possess antioxidant activity in previous studies. Oxidative stress has been linked to the pathogenesis of major depressive disorder (MDD) with evidence of increased serum levels of oxidative stress biomarkers in MDD patients. OBJECTIVE: The present study aimed to evaluate the antidepressant activity of M. sapientum stem extract (MSSE) in experimental models in mice. MATERIALS AND METHODS: Forced swim test (FST) and tail suspension test (TST) were carried out in five different groups (n = 6/group) of mice...
October 2016: Pharmacognosy Research
https://www.readbyqxmd.com/read/27695258/in-vivo-study-on-depressant-effects-and-muscle-coordination-activity-of-galphimia-glauca-stem-methanol-extract
#9
Baba Shankar Rao Garige, Srisailam Keshetti, Uma Maheshwara Rao Vattikuti
BACKGROUND: Galphimia glauca is an evergreen shrub found across peninsular India, belonging to family Malpighiaceae. OBJECTIVE: The objective of this study was to assess the in vivo depressant effects and muscle coordination activity of G. glauca stem methanol extract (GGSME). MATERIALS AND METHODS: The stem methanol extract was administered in Swiss albino mice in 1 day to study the central nervous system (CNS) depressant and muscle coordination activity employing animal models such as sodium pentobarbital-induced sleep test, hole-board test, open field test, pentylenetetrazole (PTZ)-induced convulsions, picrotoxin-induced convulsions, grip strengthening test in mice, and Rota-rod test...
October 2016: Pharmacognosy Research
https://www.readbyqxmd.com/read/27668874/global-analysis-of-type-three-secretion-system-and-quorum-sensing-inhibition-of-pseudomonas-savastanoi-by-polyphenols-extracts-from-vegetable-residues
#10
Carola Biancalani, Matteo Cerboneschi, Francesco Tadini-Buoninsegni, Margherita Campo, Arianna Scardigli, Annalisa Romani, Stefania Tegli
Protection of plants against bacterial diseases still mainly relies on the use of chemical pesticides, which in Europe correspond essentially to copper-based compounds. However, recently plant diseases control is oriented towards a rational use of molecules and extracts, generally with natural origin, with lower intrinsic toxicity and a reduced negative environmental impact. In this work, polyphenolic extracts from vegetable no food/feed residues of typical Mediterranean crops, as Olea europaea, Cynara scolymus, and Vitis vinifera were obtained and their inhibitory activity on the Type Three Secretion System (TTSS) and the Quorum Sensing (QS) of the Gram-negative phytopathogenic bacterium Pseudomonas savastanoi pv...
2016: PloS One
https://www.readbyqxmd.com/read/27563412/papaver-rhoeas-l-hydroalcoholic-extract-exacerbates-forced-swimming-test-induced-depression-in-mice
#11
Naser Osanloo, Akram Najafi-Abedi, Fatemeh Jafari, Farshid Javid, Mohsen Pirpiran, Mohammad-Reza Memar Jafari, Seyed Ali Mousavi Khosravi, Mohammad Rahimzadeh Behzadi, Mina Ranjbaran, Hedayat Sahraei
INTRODUCTION: Depression is one of the most frequent psychiatric disorders in the world with occurs with higher incidence in women. In the present study, the effect of water-alcoholic extract of Papaver rhoeas L. on forced swimming test (FST) in Swiss-Webster mice were examined. METHODS: We used Swiss-Webster mice (20-25 g) to execute FST on them. The plant extract (1, 10, 30, and 100 mg/kg) was injected to the animals 30 minutes before each session. Fluoxetine (20 mg/kg) was used as standard antidepressant drug...
July 2016: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/27540320/recent-updates-in-neuroprotective-and-neuroregenerative-potential-of-centella-asiatica
#12
REVIEW
Yogeswaran Lokanathan, Norazzila Omar, Nur Nabilah Ahmad Puzi, Aminuddin Saim, Ruszymah Hj Idrus
Centella asiatica, locally well known in Malaysia as pegaga, is a traditional herb that has been used widely in Ayurvedic medicine, traditional Chinese medicine, and in the traditional medicine of other Southeast Asian countries including Malaysia. Although consumption of the plant is indicated for various illnesses, its potential neuroprotective properties have been well studied and documented. In addition to past studies, recent studies also discovered and/or reconfirmed that C. asiatica acts as an antioxidant, reducing the effect of oxidative stress in vitro and in vivo...
January 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27516722/caffeoylquinic-acid-derivatives-extract-of-erigeron-multiradiatus-alleviated-acute-myocardial-ischemia-reperfusion-injury-in-rats-through-inhibiting-nf-kappab-and-jnk-activations
#13
Zhifeng Zhang, Yuan Liu, Xuecong Ren, Hua Zhou, Kaishun Wang, Hao Zhang, Pei Luo
Erigeron multiradiatus (Lindl.) Benth. has been used in Tibet folk medicine to treat various inflammatory diseases. The aim of this study was to investigate antimyocardial ischemia and reperfusion (I/R) injury effect of caffeoylquinic acids derivatives of E. multiradiatus (AE) in vivo and to explain underling mechanism. AE was prepared using the whole plant of E. multiradiatus and contents of 6 caffeoylquinic acids determined through HPLC analysis. Myocardial I/R was induced by left anterior descending coronary artery occlusion for 30 minutes followed by 24 hours of reperfusion in rats...
2016: Mediators of Inflammation
https://www.readbyqxmd.com/read/27484193/endocannabinoid-system-role-in-depression-reward-and-pain-control-review
#14
Wen-Juan Huang, Wei-Wei Chen, Xia Zhang
Depression and pain co-exist in almost 80% of patients and are associated with impaired health-related quality of life, often contributing to high mortality. However, the majority of patients who suffer from the comorbid depression and pain are not responsive to pharmacological treatments that address either pain or depression, making this comorbidity disorder a heavy burden on patients and society. In ancient times, this depression-pain comorbidity was treated using extracts of the Cannabis sativa plant, known now as marijuana and the mode of action of Δ9‑tetrahydrocannabinol, the active cannabinoid ingredient of marijuana, has only recently become known, with the identification of cannabinoid receptor type 1 (CB1) and CB2...
October 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27467225/celery-root-extract-as-an-inducer-of-mania-induction-in-a-patient-on-venlafaxine-and-st-john-s-wort
#15
Zaira Khalid, Ferdnand C Osuagwu, Bilal Shah, Nikita Roy, James E Dillon, Ronald Bradley
Celery root belongs to a group of plants classified as the umbelliferous family, which contains phytoestrogens. Phytoestrogens are structurally similar to estrogen as they share a pair of hydroxyl groups and phenolic ring, which enables them to bind to estrogen receptors directly, making them a herbal remedy for low estrogen states such as menopause. We present a case of a female patient with depression who was stabilized on venlafaxine and St John's Wort, and who developed a manic episode due to elevated serum venlafaxine levels after she started taking celery extracts for menopausal related issues...
September 2016: Postgraduate Medicine
https://www.readbyqxmd.com/read/27462333/neuroprotective-activity-of-hypericum-perforatum-and-its-major-components
#16
REVIEW
Ana I Oliveira, Cláudia Pinho, Bruno Sarmento, Alberto C P Dias
Hypericum perforatum is a perennial plant, with worldwide distribution, commonly known as St. John's wort. It has been used for centuries in traditional medicine for the treatment of several disorders, such as minor burns, anxiety, and mild to moderate depression. In the past years, its antidepressant properties have been extensively studied. Despite that, other H. perforatum biological activities, as its neuroprotective properties have also been evaluated. The present review aims to provide a comprehensive summary of the main biologically active compounds of H...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27445814/antioxidant-antinociceptive-and-cns-activities-of-viscum-orientale-and-high-sensitive-quantification-of-bioactive-polyphenols-by-uplc
#17
Amina Khatun, Mahmudur Rahman, Md Mahfizur Rahman, Hemayet Hossain, Ismet A Jahan, Mst Luthfun Nesa
Viscum orientale Willd. (Loranthaceae) has long been used in traditional medicine to treat pain, neuropharmacological disorders and various forms of tumor but not yet been reported. The aim of this study is to rationalize the traditional medicinal use of this plant by evaluating the methanol extract of V. orientale leaves (MEVOL) for anti-nociceptive, CNS depressant and antioxidant activities and to quantify the bioactive polyphenols present in this plant. Five polyphenolic compounds namely gallic acid, vanillic acid, caffeic acid, ellagic acid, and quercetin (17...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27428009/cannabinoids-for-fibromyalgia
#18
REVIEW
Brian Walitt, Petra Klose, Mary-Ann Fitzcharles, Tudor Phillips, Winfried Häuser
BACKGROUND: This review is one of a series on drugs used to treat fibromyalgia. Fibromyalgia is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue affecting approximately 2% of the general population. People often report high disability levels and poor health-related quality of life (HRQoL). Drug therapy focuses on reducing key symptoms and disability, and improving HRQoL. Cannabis has been used for millennia to reduce pain and other somatic and psychological symptoms...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27413314/comparison-between-the-effect-of-lawsonia-inermis-and-flubendazole-on-strongyloides-species-using-scanning-electron-microscopy
#19
Khadiga Ahmed Ismail, Ayman Nabil Ibrahim, Mona Abdel-Fattah Ahmed, Mona Hafez Hetta
Strongyloides species is a helminth of worldwide distribution primarily in tropical and subtropical regions. It is the only soil-transmitted helminth with the ability for autoinfection so; it may lead to severe systemic manifestations especially in immunosuppressed patients. Chemotherapy is currently considered the best therapeutic option for strongyloidiasis but some drugs are expensive and others have side effects as nausea, diarrhea and headache. Strongyloides larva is resistant to most chemical agents so, search for plant extracts may provide other effective but less expensive treatment...
June 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27358651/behavioural-studies-on-the-ethanol-leaf-extract-of-grewia-carpinifolia-in-wistar-rats
#20
Olamide E Adebiyi, Funmilayo E Olopade, James O Olopade, Funsho O Olayemi
BACKGROUND: Grewia carpinifolia is a plant commonly used in the tropics to manage various central nervous system (CNS) disorders. However, despite its widespread use no scientific work has been reported to validate these claims. OBJECTIVES: To evaluate the activity of G. carpinifolia as it affects behaviour using animal model. METHODS: Twenty five adult Wistar rats were randomly divided into five groups (A-E). Group A served as control (given only distilled water), Groups B, C, D and E were administered with single oral dose of ethanol extract of G...
March 2016: African Health Sciences
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