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https://www.readbyqxmd.com/read/28644158/radiology-case-of-the-month-idiopathic-cd4-lymphocytopenia
#1
Chris Malone, Neel D Gupta, Amit Kothari, Enrique Palacios, Harold Neitzschman
A 39 year-old male with a history of diabetes, retinitis pigmentosa, and genital warts presented with intractable occipital headaches accompanied with nausea and vomiting. The patient had markedly depressed CD4 counts. Furthermore the patient tested negative for HIV and HTLV 1/2 and had normal immunoglobulin levels. During hospital course the patient underwent a lumbar puncture and multiple imaging exams, including both CT and MR. Except for occasional nausea and vomiting controlled by therapeutic lumbar punctures, phenergan, and dilaudid the patient's hospital course was uncomplicated...
May 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28634662/hiv-stigma-and-substance-use-among-hiv-positive-russians-with-risky-drinking
#2
E Jennifer Edelman, Karsten Lunze, Debbie M Cheng, Dmitry A Lioznov, Emily Quinn, Natalia Gnatienko, Carly Bridden, Christine E Chaisson, Alexander Y Walley, Evgeny M Krupitsky, Anita Raj, Jeffrey H Samet
The link between HIV stigma with substance use is understudied. We characterized individuals with high HIV stigma and examined whether HIV stigma contributes to substance use among HIV-positive Russians reporting risky alcohol use. We analyzed data from HERMITAGE, a randomized controlled trial of 700 people living with HIV/AIDS (PLWHA) with past 6-month risky sex and risky alcohol use in St. Petersburg, Russia (2007-2011). Participants who were female and reported depressive symptoms and lower social support were more likely to endorse high HIV stigma (all p's < 0...
June 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28634661/depression-and-art-initiation-among-hiv-serodiscordant-couples-in-kenya-and-uganda
#3
Jennifer Velloza, Connie Celum, Jessica E Haberer, Kenneth Ngure, Elizabeth Irungu, Nelly Mugo, Jared M Baeten, Renee Heffron
Depression is a known barrier for antiretroviral therapy (ART) adherence, but less is understood about its effects on ART initiation. We followed 1013 HIV-infected individuals participating in the Partners Demonstration Project, an open-label study of integrated pre-exposure prophylaxis (PrEP) and ART delivery for HIV serodiscordant couples in Kenya and Uganda. Associations between depression, measured annually with the Hopkins Symptoms Checklist-Depression (HSCL-D), and ART initiation were assessed with Cox proportional hazards regression...
June 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28632809/acquired-epidermodysplasia-verruciformis-occurring-in-a-renal-transplant-recipient
#4
Jill K Henley, Eric W Hossler
Acquired epidermodysplasia verruciformis (EDV) is a rare condition occurring in patients with depressed cellular immunity, particularly individuals with human immunodeficiency virus (HIV). Acquired EDV is less commonly reported in recipients of stem cell or solid organ transplantation. This condition typically manifests within 5 years of initial immunosuppression and can present as multiple hypopigmented to red, tinea versicolor-like macules or as multiple verrucous, flat-topped papules distributed over the trunk, arms, and legs...
May 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28632477/antiretroviral-therapy-adherence-and-self-efficacy-among-people-living-with-hiv-and-a-history-of-drug-use-in-vietnam
#5
Li Li, Chunqing Lin, Sung-Jae Lee, Le Anh Tuan, Nan Feng, Nguyen Anh Tuan
People living with HIV with a history of drug use face additional psychosocial challenges that could compromise their adherence to antiretroviral therapy (ART). This study examined ART treatment adherence and adherence self-efficacy among people living with HIV with a history of drug use in Vietnam. We used cross-sectional baseline data collected between October 2014 and February 2015 from a randomized controlled trial in Vietnam. Of the 900 persons with a history of drug use in the trial, a sample of 109 people living with HIV currently on ART were included in the study...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28626358/psychosocial-correlates-of-patient-provider-family-planning-discussions-among-hiv-infected-pregnant-women-in-south-africa
#6
Violeta J Rodriguez, Ryan R Cook, Stephen M Weiss, Karl Peltzer, Deborah L Jones
Patient-provider family planning discussions and preconception counseling can reduce maternal and neonatal risks by increasing adherence to provider recommendations and antiretroviral medication. However, HIV-infected women may not discuss reproductive intentions with providers due to anticipation of negative reactions and stigma. This study aimed to identify correlates of patient-provider family planning discussions among HIV-infected women in rural South Africa, an area with high rates of antenatal HIV and suboptimal rates of prevention of mother-to-child transmission (PMTCT) of HIV...
2017: Open Access J Contracept
https://www.readbyqxmd.com/read/28623361/burden-of-sleep-disturbances-and-associated-risk-factors-a-cross-sectional-survey-among-hiv-infected-persons-on-antiretroviral-therapy-across-china
#7
Xiaojie Huang, Huiqin Li, Kathrine Meyers, Wei Xia, Zhihao Meng, Chongxi Li, Jinsong Bai, Shenghua He, Weiping Cai, Chengyu Huang, Shuiqing Liu, Hui Wang, Xuemei Ling, Ping Ma, Daling Tan, Fuxiang Wang, Lianguo Ruan, Hongxin Zhao, Hongxia Wei, Yanfen Liu, Jianhua Yu, Hongzhou Lu, Min Wang, Tong Zhang, Hui Chen, Hao Wu
This study evaluated the prevalence and factors associated with sleep disturbance in a large cohort of HIV-infected patients across China. A cross-sectional study was conducted among HIV-infected patients on antiretroviral therapy at 20 AIDS clinics. The Pittsburgh Sleep Quality Index was self-administered by subjects. Socio-demographic characteristics, medical history and HIV-related clinical data were collected. 4103 patients had complete data for analysis. Sleep disturbances were observed in 43.1% of patients...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28622034/the-experiences-of-newly-diagnosed-men-who-have-sex-with-men-entering-the-hiv-care-cascade-in-lima-peru-2015-2016-a-qualitative-analysis-of-counselor-participant-text-message-exchanges
#8
Erik Bayona, Luis Menacho, Eddy R Segura, Gitau Mburu, Fernando Roman, Consuelo Tristan, Elizabeth Bromley, Robinson Cabello
Mobile phone technology (mHealth) is a promising tool that has been used to improve HIV care in high-risk populations worldwide. Understanding patient perspectives of newly diagnosed men who have sex with men (MSM) in Lima, Peru during linkage and engagement in the HIV care continuum can help close the gaps in care following initial HIV diagnosis and ensure retention in continuous care. From June 2015 to March 2016, as part of a randomized controlled trial, 40 MSM participants were linked to care with an mHealth intervention within 3 months of HIV diagnosis at Via Libre clinic...
June 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28619295/effects-of-massage-therapy-on-anxiety-depression-hyperventilation-and-quality-of-life-in-hiv-infected-patients-a-randomized-controlled-trial
#9
Reychler Gregory, Caty Gilles, Arcq Aude, Lebrun Laurie, Belkhir Leïla, Yombi Jean-Cyr, Marot Jean-Christophe
INTRODUCTION: HIV infection is often preceded or accompanied by psychiatric comorbidities. These disorders improve with complementary therapies. The aim of this study was to measure the effect of massage therapy on anxiety, depression, hyperventilation and quality of life in HIV infected patients. METHOD: Adult HIV-infected patients were randomized (n=29) in massage therapy group (one hour a week during four weeks) and control group. Anxiety and depression (HADS-A and HADS-D), hyperventilation (Nijmegen questionnaire) and quality of life (WHOQOL-HIV) were evaluated at inclusion and after 4 weeks...
June 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28609401/randomized-controlled-trial-of-caregiver-training-for-hiv-infected-child-neurodevelopment-and-caregiver-well-being
#10
Judith K Bass, Robert Opoka, Itziar Familiar, Noeline Nakasujja, Alla Sikorskii, Jorem Awadu, Deborah Givon, Cilly Shohet, Sarah M Murray, Jura Augustinavicius, Tamar Mendelson, Michael Boivin
OBJECTIVES: HIV infection places children at neurodevelopmental risk; for young children in poverty, risk is compounded by compromised caregiving quality. The Mediational Intervention for Sensitizing Caregivers (MISC) program trained caregivers on fostering daily interactions with young children. We hypothesized that MISC could (1) enhance neurodevelopment of rural Ugandan HIV-infected children and (2) improve mental health outcomes of their caregivers, which might mediate improved caregiving quality...
June 12, 2017: AIDS
https://www.readbyqxmd.com/read/28608294/internalized-homophobia-and-drug-use-in-a-national-cohort-of-gay-and-bisexual-men-examining-depression-sexual-anxiety-and-gay-community-attachment-as-mediating-factors
#11
Raymond L Moody, Tyrel J Starks, Christian Grov, Jeffrey T Parsons
The minority stress process of internalized homophobia (IH) has been associated with a range of adverse health outcomes among gay and bisexual men (GBM). However, evidence is mixed regarding the effect of IH on drug use, suggesting the potential role of multiple mediated pathways. Researchers have linked depression, sexual anxiety, and gay community attachment with IH. Depression, sexual anxiety, and gay community attachment have also been linked with drug use and drug-related problems suggesting potential mediating roles...
June 12, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28606206/antenatal-depressed-mood-and-child-cognitive-and-physical-growth-at-18-months-in-south-africa-a-cluster-randomised-controlled-trial-of-home-visiting-by-community-health-workers
#12
M Tomlinson, M J Rotheram-Borus, A Scheffler, I le Roux
AIM: To examine the child outcomes at 18-months post-birth of a population cohort of women with antenatal depressed mood, half of whom were randomly chosen to receive perinatal home visits from community health workers during pregnancy. METHOD: Pregnant women in 24 neighbourhoods (98% participation) were randomised by neighbourhood to: (1) standard clinic care (SC; 12 neighbourhoods; n = 594) or (2) the Philani Intervention Program, a home visiting intervention plus standard care (12 neighbourhoods; n = 644)...
June 13, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28598903/self-reported-difficulties-with-everyday-function-cognitive-symptoms-and-cognitive-function-in-people-with-hiv
#13
Rosanna Laverick, Lewis Haddow, Marina Daskalopoulou, Fiona Lampe, Richard Gilson, Andrew Speakman, Andrea Antinori, Tina Bruun, Anna Vassilenko, Simon Collins, Alison Rodger
BACKGROUND: We determined factors associated with self-reported decline in activities of daily living (ADLs) and symptoms of cognitive impairment in HIV positive (HIV+) adults in five European clinics. METHODS: HIV+ adults underwent computerized and pen-and-paper neuropsychological tests and questionnaires of cognitive symptoms and ADLs. We considered cognitive function in five domains, psychosocial factors and clinical parameters as potentially associated with symptoms...
June 7, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28598791/croi-2017-neurologic-complications-of-hiv-infection
#14
Serena S Spudich, Beau M Ances
The brain is a major target for HIV infection and is a potential viral reservoir even in virologically well-controlled HIV-infected individuals. Data presented at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) suggested that during early HIV infection, CD4+ T cells in the meninges and choroid plexus serve as an important early site of HIV infection in the central nervous system (CNS), with brain macrophages and microglial cells becoming an important source of viral replication with advancing disease...
May 2017: Topics in Antiviral Medicine
https://www.readbyqxmd.com/read/28593797/suicidal-behaviors-among-newly-diagnosed-people-living-with-hiv-in-changsha-china
#15
Ying Liu, Lu Niu, Min Wang, Xi Chen, Shuiyuan Xiao, Dan Luo
Newly-diagnosed people living with HIV (NPLWH) are at high risk of suicide. We aimed to evaluate the prevalence of suicidal behaviors among NPLWH, and explore the relationships between HIV-related stress, depression, anxiety, and social support and suicidal ideation after diagnosed with HIV infection. A cross-sectional study was conducted using a standard set of questionnaires during 1 March 2013 and 30 September 2014 in the HIV/AIDS Voluntary Counseling and Testing Clinic of the Changsha Center for Disease Control and Prevention...
June 8, 2017: AIDS Care
https://www.readbyqxmd.com/read/28593404/association-between-depressive-symptom-patterns-and-clinical-profiles-among-persons-living-with-hiv
#16
N E Kelso-Chichetto, C N Okafor, R L Cook, A G Abraham, R Bolan, M Plankey
To describe patterns of depressive symptoms across 10-years by HIV status and to determine the associations between depressive symptom patterns, HIV status, and clinical profiles of persons living with HIV from the Multicenter AIDS Cohort Study (N = 980) and Women's Interagency HIV Study (N = 1744). Group-based trajectory models were used to identify depressive symptoms patterns between 2004 and 2013. Multinomial logistic regressions were conducted to determine associations of depression risk patterns. A 3-group model emerged among HIV-negative women (low: 58%; moderate: 31%; severe: 11%); 5-groups emerged among HIV-positive women (low: 28%; moderate: 31%; high: 25%; decreased: 7%; severe: 9%)...
June 7, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28589252/manifestations-of-hiv-stigma-and-their-impact-on-retention-in-care-for-people-transitioning-from-prisons-to-communities
#17
Rebecca Kemnitz, Theresa C Kuehl, Karli R Hochstatter, Emily Barker, Anna Corey, Elizabeth A Jacobs, Michael D Repplinger, William J Ehlenbach, David W Seal, James M Sosman, Ryan P Westergaard
BACKGROUND: While most people living with HIV who are incarcerated in United States receive appropriate HIV care while they are in prison, interruptions in antiretroviral therapy and virologic failure are extremely common after they are released. The purpose of this study was to describe whether and how HIV stigma influences continuity of care for people living with HIV while they transition from prison to community settings. METHODS: We conducted semi-structured, telephone-based interviews with 32 adults who received HIV care while residing in a Wisconsin state prison, followed by a second interview 6 months after they returned to their home community...
December 2017: Health & Justice
https://www.readbyqxmd.com/read/28588979/determinants-of-adherence-to-antiretroviral-therapy-among-hiv-positive-adults-in-sub-saharan-africa-a-systematic-review
#18
Tessa Heestermans, Joyce L Browne, Susan C Aitken, Sigrid C Vervoort, Kerstin Klipstein-Grobusch
OBJECTIVE: The rapid scale up of antiretroviral treatment (ART) in sub-Saharan Africa (SSA) has resulted in an increased focus on patient adherence. Non-adherence can lead to drug-resistant HIV caused by failure to achieve maximal viral suppression. Optimal treatment requires the identification of patients at high risk of suboptimal adherence and targeted interventions. The aim of this review was to identify and summarise determinants of adherence to ART among HIV-positive adults. DESIGN: Systematic review of adherence to ART in SSA from January 2002 to October 2014...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28587607/design-of-a-syndemic-based-intervention-to-facilitate-care-for-men-who-have-sex-with-men-with-high-risk-behaviour-the-syn-bas-in-randomized-controlled-trial
#19
Roel C A Achterbergh, Jannie J van der Helm, Wim van den Brink, Henry J C de Vries
BACKGROUND: Men who have sex with men (MSM) constitute a risk group for sexual transmitted infections (STIs), including HIV. Despite counselling interventions, risk behaviour remains high. Syndemic theory holds that psychosocial problems often co-occur, interact and mutually reinforce each other, thereby increasing high risk behaviours and co-occurring diseases. Therefore, if co-occurring psychosocial problems were assessed and treated simultaneously, this might decrease high risk behaviour and disease...
June 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28586534/working-alliance-interpersonal-problems-and-depressive-symptoms-in-tele-interpersonal-psychotherapy-for-hiv-infected-rural-persons-evidence-for-indirect-effects
#20
Timothy Anderson, Andrew S McClintock, Shannon S McCarrick, Timothy G Heckman, Bernadette D Heckman, John C Markowitz, Mark Sutton
OBJECTIVE: Interpersonal psychotherapy (IPT) has demonstrated efficacy for the treatment of depression, yet little is known about its therapeutic mechanisms. As a specific treatment, IPT has been shown to directly reduce depressive symptoms, although it is unclear whether these reductions occur via interpersonal changes. Within IPT, the potential role of the working alliance, a common factor, as a predictor of depression and interpersonal changes is also unclear. METHOD: Participants were 147 depressed persons living with HIV in rural communities of 28 U...
June 6, 2017: Journal of Clinical Psychology
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