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https://www.readbyqxmd.com/read/29474119/description-and-outcomes-of-a-buprenorphine-maintenance-treatment-program-integrated-within-prevention-point-philadelphia-an-urban-syringe-exchange-program
#1
Marcus A Bachhuber, Cole Thompson, Ann Prybylowski, José Benitez, Silvana Mazzella, David Barclay
BACKGROUND: Syringe exchange programs are uniquely positioned to offer treatment services to interested clients. Prevention Point Philadelphia recently expanded to offer buprenorphine maintenance treatment through its Stabilization, Treatment, and Engagement Program (STEP). OBJECTIVE: To describe the STEP model of care and report treatment outcomes. METHODS: Retrospective chart review of patients enrolled in STEP (October 2011-August 2014)...
February 23, 2018: Substance Abuse
https://www.readbyqxmd.com/read/29471677/association-between-coping-strategies-social-support-and-depression-and-anxiety-symptoms-among-rural-ugandan-women-living-with-hiv-aids
#2
Victoria Seffren, Itziar Familiar, Sarah M Murray, Jura Augustinavicius, Michael J Boivin, Noeline Nakasujja, Robert Opoka, Judith Bass
Poor mental health detrimentally affects quality of life among women living with HIV/AIDS. An improved understanding of how coping and social support relate to depression and anxiety in this population can facilitate the design and implementation of appropriate mental health treatment and support services. Secondary analysis was conducted on baseline data from 288 HIV-positive women enrolled in a parenting intervention in Uganda. Depression and anxiety symptoms, social support, and coping were assessed with the Hopkins Symptom Checklist and adapted versions of the Multidimensional Scale for Perceived Social Support and Ways of Coping Questionnaire...
February 22, 2018: AIDS Care
https://www.readbyqxmd.com/read/29470532/psychosocial-health-and-suicidal-ideation-among-people-living-with-hiv-aids-a-cross-sectional-study-in-nanjing-china
#3
Wei Wang, Chenchang Xiao, Xing Yao, Yinmei Yang, Hong Yan, Shiyue Li
BACKGROUND: Suicide is a serious cause of mortality worldwide and is considered as a psychiatric emergency. People living with HIV/AIDS (PLWHA) have higher rates of suicidal behavior than the general population. This study assessed the prevalence and verified the syndemic effect of psychosocial health conditions on suicidal ideation among PLWHA in China. METHODS: An institutional-based cross-sectional study was conducted from July to August 2016 in Nanjing, China, using a self-report questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29470512/association-between-hiv-status-and-depressive-symptoms-among-children-and-adolescents-in-the-southern-highlands-zone-tanzania-a-case-control-study
#4
Abraham Lwidiko, Stephen Matthew Kibusi, Azan Nyundo, Bonaventura C T Mpondo
BACKGROUND: Children and adolescents continue to have HIV/AIDS in southern Saharan Africa. Scaling up of HIV services has significantly improved access to ARV and consequently improved on morbidity and mortality related to HIV/AIDS including opportunistic infection. Despite the above efforts, non-communicable conditions including mental disorders such as depression have been observed to contribute to the burden of disabilities about which little is documented. This study, therefore, aimed to determine the magnitude of depressive symptoms and the associated factors among HIV-infected children and adolescents...
2018: PloS One
https://www.readbyqxmd.com/read/29468493/facilitators-and-barriers-to-pre-exposure-prophylaxis-prep-use-among-black-individuals-in-the-united-states-results-from-the-national-survey-on-hiv-in-the-black-community-nshbc
#5
Bisola O Ojikutu, Laura M Bogart, Molly Higgins-Biddle, Sannisha K Dale, Wanda Allen, Tiffany Dominique, Kenneth H Mayer
This study explores willingness to use PrEP among Black individuals in the US. From February to April 2016, an online survey was administered to a nationally representative sample of Black individuals. 855 individuals who were HIV negative by self-report participated [mean age: 33.6 (SD 9.2); 45.5% male]. Among all respondents, 14.5% were aware of, and 26.0% would be willing to use PrEP. Among high-risk individuals (N = 327), 19.8% knew about and 35.1% would be willing to use PrEP. The most common reason for lack of willingness among high-risk individuals was low self-perceived risk (65...
February 21, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29466531/association-of-increased-chronicity-of-depression-with-hiv-appointment-attendance-treatment-failure-and-mortality-among-hiv-infected-adults-in-the-united-states
#6
Brian W Pence, Jon C Mills, Angela M Bengtson, Bradley N Gaynes, Tiffany L Breger, Robert L Cook, Richard D Moore, David J Grelotti, Conall O'Cleirigh, Michael J Mugavero
Importance: Depression commonly affects adults with HIV and complicates the management of HIV. Depression among individuals with HIV tends to be chronic and cyclical, but the association of this chronicity with HIV outcomes (and the related potential for screening and intervention to shorten depressive episodes) has received little attention. Objective: To examine the association between increased chronicity of depression and multiple HIV care continuum indicators (HIV appointment attendance, treatment failure, and mortality)...
February 21, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29466443/burnout-and-self-reported-suboptimal-patient-care-amongst-health-care-workers-providing-hiv-care-in-malawi
#7
Maria H Kim, Alick C Mazenga, Katie Simon, Xiaoying Yu, Saeed Ahmed, Phoebe Nyasulu, Peter N Kazembe, Stanley Ngoma, Elaine J Abrams
BACKGROUND: The well-documented shortages of health care workers (HCWs) in sub-Saharan Africa are further intensified by the increased human resource needs of expanding HIV treatment programs. Burnout is a syndrome of emotional exhaustion (EE), depersonalization (DP), and a sense of low personal accomplishment (PA). HCWs' burnout can negatively impact the delivery of health services. Our main objective was to examine the prevalence of burnout amongst HCWs in Malawi and explore its relationship to self-reported suboptimal patient care...
2018: PloS One
https://www.readbyqxmd.com/read/29463102/social-and-behavioral-factors-associated-with-failing-second-line-art-results-from-a-cohort-study-at-the-themba-lethu-clinic-johannesburg-south-africa
#8
Denise Evans, Sara Dahlberg, Rebecca Berhanu, Tembeka Sineke, Caroline Govathson, Ingrid Jonker, Elisabet Lönnermark, Matthew P Fox
Poor adherence is a main challenge to successful second-line ART in South Africa. Studies have shown that patients can re-suppress their viral load following intensive adherence counselling. We identify factors associated with failure to re-suppress on second-line ART. The study was a retrospective cohort study which included HIV-positive adults who experienced an elevated viral load ≥400 copies/ml on second-line ART between January 2013-July 2014, had completed an adherence counselling questionnaire and had a repeat viral load result recorded within 6 months of intensive adherence counselling...
February 21, 2018: AIDS Care
https://www.readbyqxmd.com/read/29461096/associations-among-trajectories-of-sleep-disturbance-depressive-symptomology-and-24-hour-urinary-cortisol-in-hiv-women-following-a-stress-management-intervention
#9
Roger McIntosh, Michael Antoni, Julia Seay, Mary Ann Fletcher, Gail Ironson, Nancy Klimas, Mahendra Kumar, Neil Schneiderman
OBJECTIVE: The burden of sleep disturbance and depressive symptomology is high for persons living with HIV and particularly so for women. While cognitive behavioral stress management (CBSM) is shown to reduce symptoms of depression and 24-hr urinary free cortisol output (CORT) in HIV+ men, less is known about the effects of CBSM on mood and concomitant sleep disturbance in HIV+ women. The study aim is to model longitudinal change in sleep disturbance, depressive symptomology, and CORT for HIV+ women exposed to a 12-week CBSM intervention or control condition...
February 20, 2018: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/29460107/assessing-psychiatric-symptoms-in-youth-affected-by-hiv-comparing-a-brief-self-administered-rating-scale-with-a-structured-diagnostic-interview
#10
Miriam Chernoff, Konstantia Nadia Angelidou, Paige L Williams, Pim Brouwers, Meredith Warshaw, Sharon Nachman
Brief psychiatric assessment tools are needed for evaluating children affected by HIV for emotional and behavioral problems. We compared a self-administered symptom rating scale (CASI-4R) to a semi-structured diagnostic interview (DICA-P) in 136 U.S. children affected by HIV. Agreement and performance measures for the two instruments were computed for attention deficit hyperactivity disorder, depression, anxiety, and disruptive behavior. Correlations and regression analyses were conducted to compare the two instruments, and to evaluate their associations with social, academic, and global function...
February 19, 2018: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/29454927/syndemics-among-individuals-enrolled-in-the-prep-brasil-study
#11
Raquel B De Boni, Iona K Machado, Mauricio T L De Vasconcellos, Brenda Hoagland, Esper G Kallas, José Valdez Madruga, Nilo M Fernandes, Natalia B Cerqueira, Ronaldo I Moreira, Silvia P Goulart, Valdilea G Veloso, Beatriz Grinsztejn, Paula M Luz
BACKGROUND: Concurrent psychosocial problems may synergistically increase the risk of HIV infection (syndemics), representing a challenge for prevention. We aimed to evaluate the prevalence and associated factors of syndemics among men who have sex with men (MSM) and transgender women (TGW) enrolled in the Brazilian pre-exposure prophylaxis demonstration study (PrEP Brasil Study). METHODS: Secondary cross-sectional analysis of the PrEP Brasil Study was performed...
February 10, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29452219/increased-cd4-counts-pain-and-depression-are-correlates-of-lower-sleep-quality-in-treated-hiv-positive-patients-with-low-baseline-cd4-counts
#12
K N Redman, A S Karstaedt, K Scheuermaier
Poor sleep quality leads to increased immune activation and immune activation leads to worse sleep quality. South African HIV positive patients typically have delayed start of treatment, which has been associated with CD4+ effector T cells being more spontaneously activated in chronically treated patients. This cross-sectional study investigated whether subjective sleep quality was associated with CD4+ T lymphocyte reconstitution in treated South African HIV+ patients. One hundred and thirty-nine treated HIV+ patients (109 F, age average (SD)= 43 (9)) were recruited from Chris Hani Baragwanath Academic Hospital in Soweto, Johannesburg, South Africa...
February 13, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29441001/early-life-stress-related-elevations-in-reaction-time-variability-are-associated-with-brain-volume-reductions-in-hiv-adults
#13
Uraina S Clark, Miguel Arce Rentería, Rachal R Hegde, Susan Morgello
There is burgeoning evidence that, among HIV+ adults, exposure to high levels of early life stress (ELS) is associated with increased cognitive impairment as well as brain volume abnormalities and elevated neuropsychiatric symptoms. Currently, we have a limited understanding of the degree to which cognitive difficulties observed in HIV+ High-ELS samples reflect underlying neural abnormalities rather than increases in neuropsychiatric symptoms. Here, we utilized a behavioral marker of cognitive function, reaction time intra-individual variability (RT-IIV), which is sensitive to both brain volume reductions and neuropsychiatric symptoms, to elucidate the unique contributions of brain volume abnormalities and neuropsychiatric symptoms to cognitive difficulties in HIV+ High-ELS adults...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29440761/intimate-partner-violence-correlates-with-a-higher-hiv-incidence-among-msm-a-12-month-prospective-cohort-study-in-shenyang-china
#14
Hong-Yi Wang, Ning Wang, Zhen-Xing Chu, Jing Zhang, Xiang Mao, Wen-Qing Geng, Yong-Jun Jiang, Hong Shang, Jun-Jie Xu
Intimate partner violence (IPV) and HIV are highly prevalent worldwide among MSM. However, the association between IPV and HIV seroconversion is virtually unknown. This 12-month prospective cohort study was conducted among MSM in Shenyang, China to explore the causality between IPV and the incidence of HIV. Adjusted Hazard Ratios (aHRs) of HIV acquisition were derived from a multivariate time-dependent Cox model and applied to calculate population attributable fractions (PAFs). Among 476 HIV-negative MSM subjects, 89(18...
February 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29436331/impact-of-adherence-to-antidepressants-on-long-term-prescription-opioid-use-cessation
#15
Jeffrey F Scherrer, Joanne Salas, Mark D Sullivan, Brian K Ahmedani, Laurel A Copeland, Kathleen K Bucholz, Thomas Burroughs, F David Schneider, Patrick J Lustman
BACKGROUND: Depression contributes to persistent opioid analgesic use (OAU). Treating depression may increase opioid cessation. Aims To determine if adherence to antidepressant medications (ADMs) v. non-adherence was associated with opioid cessation in patients with a new depression episode after >90 days of OAU. METHOD: Patients with non-cancer, non-HIV pain (n = 2821), with a new episode of depression following >90 days of OAU, were eligible if they received ≥1 ADM prescription from 2002 to 2012...
February 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29435953/role-of-noncommunicable-diseases-ncds-in-resource-limited-settings-rls
#16
REVIEW
Mosepele Mosepele, Elizabeth Botsile
PURPOSE OF REVIEW: As access to effective antiretroviral therapy (ART) expands globally, a decline in AIDS-related morbidity and mortality has been complicated by rising rates of noncommunicable diseases (NCDs). This review provides a brief description of NCDs and existing gaps on knowledge about NCDs among HIV-infected adults mostly in Africa. RECENT FINDINGS: Recent reports show that one in every five persons living with HIV has a chronic illness, predominantly diabetes and/or hypertension, depression, and most of these conditions are either not diagnosed or not being managed...
February 12, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29432228/growth-and-pubertal-development-in-hiv-infected-adolescents
#17
Paige L Williams, Julie Jesson
PURPOSE OF REVIEW: We present an overview of recent research in the inter-related areas of growth and pubertal development among adolescents with HIV. Growth deficits early in childhood can lead to delayed puberty, with subsequent effects on pubertal growth spurts and bone health. RECENT FINDINGS: Impaired growth remains a critical concern, particularly in low-resource settings, where stunting, wasting and underweight remain pervasive. Antiretroviral treatment (ART) initiation results in improved growth, with greatest growth recovery in the first years and more improvement in weight than in height...
February 9, 2018: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29430957/anxiety-depression-and-health-related-quality-of-life-in-aging-people-living-with-hiv-compared-to-diabetes-patients-and-patients-with-minor-health-conditions-a-longitudinal-study
#18
Joram Ronel, Andreas Dinkel, Eva Wolf, Birgitt Marten-Mittag, Birgit Mueck, Christoph Mayr, Christian Hoffmann, Martin Karwat, Knud Schewe, Axel Baumgarten, Hans Jaeger
HIV infection has evolved from a fatal to a treatable condition, leading to an increase in the rate of elderly People Living with HIV (PLWH). However, little is known about the psychosocial burden of elderly PLWH. Thus, the aim of this longitudinal multi-center cohort study was to investigate whether elderly PLWH experience more anxiety and depression and reduced health related quality of life (HRQOL) compared to elderly patients with other chronic conditions. PLWH were compared to diabetes patients (DM) and patients with minor health conditions (MHC), e...
February 11, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29428881/childhood-adversity-increases-the-risk-of-onward-transmission-from-perinatal-hiv-infected-adolescents-and-youth-in-south-africa
#19
Rachel Kidman, Sharon Nachman, Janan Dietrich, Afaaf Liberty, Avy Violari
Repeated exposure to childhood adversity (abuse, neglect and other traumas experienced before age 18) can have lifelong impacts on health. For HIV-infected adolescents and youth, such impacts may include onward transmission of HIV. To evaluate this possibility, the current study measured the burden of childhood adversity and its influence on risky health behaviors among perinatally-infected adolescents and youth. We surveyed 250 perinatally-infected adolescents and youth (13-24 years) receiving care in Soweto, South Africa...
February 8, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29427232/does-maternal-hiv-disclosure-self-efficacy-enhance-parent-child-relationships-and-child-adjustment
#20
Lisa Armistead, Nada Goodrum, Marya Schulte, William Marelich, Rebecca LeCroix, Debra A Murphy
Nondisclosure of maternal HIV status to young children can negatively impact child functioning; however, many mothers do not disclose due to lack of self-efficacy for the disclosure process. This study examines demographic variations in disclosure self-efficacy, regardless of intention to disclose, and assesses the relationship between self-efficacy and child adjustment via the parent-child relationship among a sample of HIV+ mothers and their healthy children (N = 181 pairs). Mothers completed demographic and self-efficacy measures; children completed measures assessing the parent-child relationship and child adjustment (i...
February 9, 2018: AIDS and Behavior
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