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https://www.readbyqxmd.com/read/28445088/predicting-the-need-for-third-line-antiretroviral-therapy-by-identifying-patients-at-high-risk-for-failing-second-line-antiretroviral-therapy-in-south-africa
#1
Dorina Onoya, Cornelius Nattey, Eric Budgell, Liudmyla van den Berg, Mhairi Maskew, Denise Evans, Kamban Hirasen, Lawrence C Long, Matthew P Fox
Although third-line antiretroviral therapy (ART) is available in South Africa's public sector, its cost is substantially higher than first and second line. Identifying risk factors for failure on second-line treatment remains crucial to reduce the need for third-line drugs. We conducted a case-control study including 194 adult patients (≥18 years; 70 cases and 124 controls) who initiated second-line ART in Johannesburg, South Africa. Unconditional logistic regression was used to assess predictors of virologic failure (defined as 2 consecutive viral load measures ≥1000 copies/mL, ≥3 months after switching to second line)...
April 26, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28444470/sexual-orientation-differences-in-health-and-wellbeing-among-women-living-with-hiv-in-canada-findings-from-a-national-cohort-study
#2
Carmen H Logie, Ashley Lacombe-Duncan, Ying Wang, Angela Kaida, Alexandra de Pokomandy, Kath Webster, Tracey Conway, Mona Loutfy
Sexual orientation differences in health and wellbeing among women living with HIV (WLH) are underexplored. Limited research available, however, suggests that sexual minority WLH may experience barriers to HIV care. Cross-sectional baseline data was analyzed from a Canadian cohort study with WLH (sexual minority women [SMW]: n = 180; heterosexual women: n = 1240). SMW (median age 38 years, IQR 13) included bisexual (58.9%), lesbian (17.8%) and other sexualities (23.3%). In multivariable analyses adjusting for age, poverty, education, and ethnicity, SMW identity was associated with increased odds of: clinical (80% vs...
April 25, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28444004/relation-between-hiv-status-risky-sexual-behavior-and-mental-health-in-an-msm-sample-from-three-chilean-cities
#3
Fabiola Gómez, Jaime Barrientos, Manuel Cárdenas
Objective: To explore the association among HIV status; negative psychological symptoms (anxiety, depression, and hostility); and risky sexual behaviors (multiple sexual partners and unprotected sexual intercourse) in a Chilean sample of men who have sex with men (MSM). Methods: This study had a cross-sectional design and a sample of 325 MSM whose ages ranged from 18 to 64 years (mean: 30.8; standard deviation: 9.8). Association tests (chi-squared) and group mean comparisons (Student's t-tests and F-tests) were performed...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28439754/association-between-depression-and-antiretroviral-therapy-use-among-people-living-with-hiv-a-meta-analysis
#4
REVIEW
Jun Tao, Sten H Vermund, Han-Zhu Qian
Depression is common among people living with HIV (PLHIV). Studies on the relationship between depression and use of antiretroviral therapy (ART) are inconclusive. A meta-analysis was conducted to summarize the relationship between depression and ART use among PLHIV. Ten electronic databases, conference abstracts, and dissertations were searched. A random effects meta-analysis was performed to pool the odds ratio estimates from eligible studies. Subgroup analyses and meta-regression were conducted for moderator analysis...
April 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28438030/non-specialist-psychosocial-support-interventions-for-women-living-with-hiv-a-systematic-review
#5
Laura K Beres, Manjulaa Narasimhan, Jennifer Robinson, Alice Welbourn, Caitlin E Kennedy
Many women living with HIV experience a range of physical, social, and psychological challenges linked to their HIV status. Psychosocial support interventions may help women cope with these challenges and may allow women to make better decisions around their sexual and reproductive health (SRH), yet no reviews have summarized the evidence for the impact of such interventions on well-being and SRH decision-making among women living with HIV. We systematically reviewed the evidence for non-specialist delivered psychosocial support interventions for women living with HIV, which are particularly relevant in low-resource settings...
April 24, 2017: AIDS Care
https://www.readbyqxmd.com/read/28436758/amphetamine-type-stimulants-ats-use-and-homosexuality-related-enacted-stigma-are-associated-with-depression-among-men-who-have-sex-with-men-msm-in-two-major-cities-in-vietnam-in-2014
#6
Nga Thi Thu Vu, Martin Holt, Huong Thi Thu Phan, Lan Thi La, Gioi Minh Tran, Tung Thanh Doan, Trang Nguyen Nhu Nguyen, John de Wit
BACKGROUND: Men who have sex with men (MSM) are disproportionately affected by mental health concerns, including depression. Amphetamine-type-stimulants (ATS) use and homosexuality-related stigma and discrimination have been found associated with depression among MSM. OBJECTIVES: To assess the prevalence of depression and its associations with ATS use and homosexuality-related stigma and discrimination among MSM in Vietnam. METHODS: 622 MSM were conveniently recruited in Hanoi and Ho Chi Minh city, Vietnam, from September to December 2014...
April 24, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28434253/risky-sexual-behaviors-as-correlates-of-depression-and-suicidal-ideation-among-male-hiv-test-seekers-at-a-voluntary-counseling-and-testing-facility-in-taiwan
#7
Chia-Chun Lin, Yuan-Ti Lee, Hao-Jan Yang
This study aims at determining the level of depression and suicidal status of adult HIV test-seekers. Of the total enrolled 850 males, almost 50% reported some risk behaviors, 38.9% experienced depression, and 7.2% had suicidal ideation. Subjects with risky sexual behaviors in terms of repeated HIV test, had a history of sexually transmitted disease, engaged in one-night stands, or did not use condoms all the time with causal sexual partners were more likely to have depression. Furthermore, subjects who were bisexual/homosexual, engaged in Internet sex, engaged in one-night stands, or used addictive drugs within the past 6 months were more likely to experience suicidal ideation...
April 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28430844/effects-of-antiretroviral-therapy-and-depressive-symptoms-on-all-cause-mortality-among-hiv-infected-women
#8
Jonathan V Todd, Stephen R Cole, Brian W Pence, Catherine R Lesko, Peter Bacchetti, Mardge H Cohen, Daniel J Feaster, Stephen Gange, Michael E Griswold, Wendy Mack, Anna Rubtsova, Cuiwei Wang, Jeremy Weedon, Kathryn Anastos, Adaora A Adimora
Depression affects up to 30% of human immunodeficiency virus (HIV)-infected individuals. We estimated joint effects of antiretroviral therapy (ART) initiation and depressive symptoms on time to death using a joint marginal structural model and data from a cohort of HIV-infected women from the Women's Interagency HIV Study (conducted in the United States) from 1998-2011. Among 848 women contributing 6,721 years of follow-up, 194 participants died during follow-up, resulting in a crude mortality rate of 2.9 per 100 women-years...
April 18, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28429290/association-of-long-term-patterns-of-depressive-symptoms-and-attention-executive-function-among-older-men-with-and-without-human-immunodeficiency-virus
#9
Nicole M Armstrong, Pamela J Surkan, Glenn J Treisman, Ned C Sacktor, Michael R Irwin, Linda A Teplin, Ron Stall, Eileen M Martin, James T Becker, Cynthia Munro, Andrew J Levine, Lisa P Jacobson, Alison G Abraham
Older HIV-infected men are at higher risk for both depression and cognitive impairments, compared to HIV-uninfected men. We evaluated the association between longitudinal patterns of depressive symptoms and attention/executive function in HIV-infected and HIV-uninfected men aged 50+ years to understand whether HIV infection influenced the long-term effect of depression on attention/executive function. Responses to the Center for Epidemiologic Studies-Depression scale and attention/executive function tests (Trail Making Test Part B and Symbol Digit Modalities Test) were collected semiannually from May 1986 to April 2015 in 1611 men...
April 20, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28429289/the-nature-and-consequences-of-cognitive-deficits-among-tobacco-smokers-with-hiv-a-comparison-to-tobacco-smokers-without-hiv
#10
Joseph D Harrison, Jessica A Dochney, Sonja Blazekovic, Frank Leone, David Metzger, Ian Frank, Robert Gross, Anita Hole, Karam Mounzer, Steven Siegel, Robert A Schnoll, Rebecca L Ashare
HIV-infected smokers lose more years of life to tobacco-related disease than HIV. Since neurocognitive deficits are common among those with HIV and are associated with smoking persistence, these deficits may be a unique barrier to smoking cessation among HIV-infected smokers. Documenting unique differences in and correlates of cognition among HIV-infected smokers is a critical step towards developing a population-specific tobacco cessation treatment. We compared neurocognitive function between HIV-infected (n = 103) and HIV-uninfected smokers (n = 70), accounting for demographic and smoking-related variables...
April 20, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28426532/impact-of-co-morbidity-and-aging-on-health-related-quality-of-life-in-hiv-positive-and-hiv-negative-individuals
#11
N Langebeek, K W Kooij, F W Wit, I G Stolte, M A G Sprangers, P Reiss, P T Nieuwkerk
BACKGROUND: HIV-infected individuals may be at risk for the premature onset of age-associated non-communicable co-morbidities. Being HIV-positive, having comorbidities and being of higher age may adversely impact health-related quality of life (HRQL). We investigated the possible contribution of HIV infection, co-morbidities, and age on HRQL and depression. METHODS: HIV-infected individuals and uninfected controls from the AGEhIV Cohort Study were screened for the presence of co-morbidities...
April 19, 2017: AIDS
https://www.readbyqxmd.com/read/28426364/patterns-of-mood-and-personality-factors-and-associations-with-sti-hiv-related-drug-and-sex-risk-among-african-american-male-inmates
#12
Joy D Scheidell, Carl W Lejuez, Carol E Golin, Adaora A Adimora, David A Wohl, Larry D Keen, Michael Hammond, Selena Judon-Monk, Maria R Khan
BACKGROUND: Research on the association between antisocial personality disorder (ASPD) with comorbid mental disorders and sexually transmitted infection (STI)/HIV risk among inmates is scant despite the high prevalence of psychopathology and of STI/HIV in this population. METHODS: We used baseline data from Project DISRUPT, a cohort study conducted among incarcerated African American men (n = 207), to measure associations between ASPD and STI/HIV risk. We also conducted latent class analyses (LCAs) to identify subgroups defined by ASPD with comorbid stress, depression, and borderline personality disorder symptoms and measured associations between latent class membership and STI/HIV risk...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28422615/understanding-how-sexual-and-gender-minority-stigmas-influence-depression-among-trans-women-and-men-who-have-sex-with-men-in-india
#13
Venkatesan Chakrapani, Pandara Purayil Vijin, Carmen H Logie, Peter A Newman, Murali Shunmugam, Murugesan Sivasubramanian, Miriam Samuel
PURPOSE: Few studies have assessed how sexual and gender minority stigmas affect the mental health of trans women and self-identified men who have sex with men (MSM) in India, populations with a high HIV burden. We tested whether social support and resilient coping act as mediators of the effect of sexual and gender minority stigmas on depression as proposed by Hatzenbuehler's psychological mediation framework, or as moderators based on Meyer's minority stress theory. METHODS: We conducted a cross-sectional survey among trans women (n = 300) and MSM (n = 300) recruited from urban and rural sites in India...
April 19, 2017: LGBT Health
https://www.readbyqxmd.com/read/28418984/anger-and-quality-of-life-in-patients-co-infected-with-hiv-and-hepatitis-c-virus-a-cross-sectional-study-anrs-co13-hepavih
#14
Fabienne Marcellin, Camelia Protopopescu, Laure Esterle, Linda Wittkop, Lionel Piroth, Hugues Aumaitre, Olivier Bouchaud, Cécile Goujard, Daniel Vittecoq, François Dabis, Dominique Salmon-Ceron, Bruno Spire, Perrine Roux, Maria P Carrieri
OBJECTIVE: The aim of this study is to document the relationship between anger dimensions (state, trait, expression, and control) and quality of life (QoL) in patients co-infected with HIV and hepatitis C virus (HCV). PATIENTS AND METHODS: This is a cross-sectional study nested in the ANRS CO13-HEPAVIH French national cohort. Anger and QoL were assessed using self-administered questionnaires in 536 HIV-HCV-co-infected patients. Correlations between anger scores (STAXI-2 scale) and QoL scores (WHOQOL-HIV BREF scale) were assessed using Spearman's coefficients...
April 17, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28417433/investigating-responses-to-food-insecurity-among-hiv-positive-people-in-resource-rich-settings-a-systematic-review
#15
REVIEW
F H McKay, K Lippi, M Dunn
Many of the 36.7 million people living with HIV are also assumed to be food insecure. The implications of food insecurity in people living with HIV are significant, with food insecurity associated with an increased likelihood of tobacco, alcohol, and illicit drug use, experiences of depression or depressive symptoms, poor adherence and delayed uptake of HIV medication, nutritional vulnerability leading to interference of medication, and the uptake of risky behaviours as a way to gain access to food resources...
April 17, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28412229/characteristics-and-factors-associated-with-pain-in-older-homeless-individuals-results-from-the-hope-home-study
#16
John C Landefeld, Christine Miaskowski, Lina Tieu, Claudia Ponath, Christopher T Lee, David Guzman, Margot Kushel
Individuals experiencing homelessness in the United States are aging; little is known about chronic pain in this population. In a cross-sectional, population-based study, we interviewed 350 homeless individuals aged 50 and older to describe pain experienced by older persons experiencing homelessness and to assess factors associated with chronic moderate to severe pain, defined as pain lasting ≥3 months, with a past week average severity score of 5-10 (scale 0-10). The median age of participants was 58 years...
April 12, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28410973/the-influence-of-relationship-power-and-partner-communication-on-the-syndemic-factor-among-hispanic-women
#17
Rosa M Gonzalez-Guarda, Brian E McCabe, Esther Mathurin, Summer D DeBastiani, Nilda Peragallo Montano
BACKGROUND: This study expands research on the substance abuse, intimate partner violence, human immunodeficiency virus (HIV), and depression syndemic theory for Hispanic women. We hypothesized relationship power and partner communication would be related to the syndemic. METHODS: Data were used from the baseline assessment of an effectiveness trial of SEPA (Salud/Health, Educación/Education, Prevención/Prevention, and Autocuidado/Self-care), an HIV/sexually transmitted infection risk reduction program for Hispanic women...
April 11, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28407737/pain-in-amaxhosa-women-living-with-hiv-aids-a-cross-sectional-study-of-ambulant-outpatients
#18
Romy Parker, Jennifer Jelsma, Dan J Stein
BACKGROUND: Pain is one of the most commonly reported symptoms in people living with HIV/AIDS, whether or not they are receiving anti-retroviral therapy. A recent systematic review identified a paucity of studies exploring pain in women in low and middle income countries. The prevalence and characteristics of pain in women living with HIV/AIDS may differ from that of men as many chronic pain conditions are more prevalent in women. The aims of this study were to establish pain prevalence, characteristics and management in amaXhosa women living with HIV/AIDS...
April 13, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28406598/factors-associated-with-sex-work-involvement-among-transgender-women-in-jamaica-a-cross-sectional-study
#19
Carmen H Logie, Ying Wang, Ashley Lacombe-Duncan, Nicolette Jones, Uzma Ahmed, Kandasi Levermore, Ava Neil, Tyrone Ellis, Nicolette Bryan, Annecka Marshall, Peter A Newman
INTRODUCTION: Transgender women are disproportionately impacted by HIV. Transgender women involved in sex work may experience exacerbated violence, social exclusion, and HIV vulnerabilities, in comparison with non-sex work-involved transgender women. Scant research has investigated sex work among transgender women in the Caribbean, including Jamaica, where transgender women report pervasive violence. The study objective was to examine factors associated with sex work involvement among transgender women in Jamaica...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28406276/world-health-day-focus-on-hiv-and-depression-a-comorbidity-with-specific-challenges
#20
REVIEW
Lorraine Sherr, Lucie Cluver
No abstract text is available yet for this article.
April 7, 2017: Journal of the International AIDS Society
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