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Endocarditis enterococcus

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https://www.readbyqxmd.com/read/29131251/ischemic-stroke-and-st-elevation-myocardial-infarction-revealing-infective-endocarditis
#1
G-R Joliat, N Halkic, O Pantet, N Ben-Hamouda
In this clinical scenario, we report the case of a patient who presented multiple embolic complications due to mitral infective endocarditis (IE). A 68-year-old woman had extended right hepatectomy for hilar cholangiocarcinoma. Unfortunately, she had multiple postoperative complications and had to be transferred to the Intensive Care Unit. During this stay, we have diagnosed an Enterococcus faecium IE after the occurrence of multiple embolic complications (myocardial infarction, ischemic stroke, digital emboli, splenic emboli, and renal emboli)...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29059358/daptomycin
#2
Mohsen Heidary, Azar Dohkt Khosravi, Saeed Khoshnood, Mohammad Javad Nasiri, Saleh Soleimani, Mehdi Goudarzi
Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of Gram-positive infections including complicated skin and skin structure infections, right-sided infective endocarditis, bacteraemia, meningitis, sepsis and urinary tract infections. Daptomycin has distinct mechanisms of action, disrupting multiple aspects of cell membrane function and inhibiting protein, DNA and RNA synthesis. Although daptomycin resistance in Gram-positive bacteria is uncommon, there are increasing reports of daptomycin resistance in Staphylococcus aureus, Enterococcus faecium and Enterococcus faecalis...
October 20, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29050736/-complicated-transcatheter-aortic-valve-endocarditis-with-abscess-and-pseudoaneurysm-value-of-the-ecg-gated-multidetector-computed-tomography-angiography
#3
S Pichard, G Gibault-Genty, A Vienet-Legue, N Baron, R Convers-Domart, J L Georges, B Livarek
A 80-year-old man was admitted to catheterization room for an acute infero-lateral ST-elevation myocardial infarction (STEMI). Coronary angiography showed a thrombotic occlusion of the second left marginal branch, and normal other coronary arteries. The thrombo-embolic mechanism of the STEMI, and the infectious context in this patient who had had a transcatheter aortic valve implantation (TAVI) two months earlier, led us to suspect a bioprosthesis endocarditis. It was confirmed by transthoracic and transoesophageal echocardiography, which showed an aortic-mitral curtain abscess and aortic bioprosthesis vegetations, associated to Enterococcus faecalis bacteriemia...
November 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29043145/anca-associated-pauci-immune-glomerulonephritis-in-a-patient-with-bacterial-endocarditis-a-challenging-clinical-dilemma
#4
Andrea Cervi, Dylan Kelly, Iakovina Alexopoulou, Nader Khalidi
PURPOSE: We report the case of a 59-year-old man with chronic hepatitis B and C infection presenting with acute kidney injury and enterococcus faecalis-infective endocarditis (IE). An elevated proteinase-3 (PR3)-ANCA and pauci-immune glomerulonephritis (GN) on renal biopsy were discovered, corresponding to ANCA-mediated GN. We conducted a literature review to assess the role of ANCA in IE and treatment implications. METHODS: On systematic review of the literature, we found five previous cases whereby IE caused by streptococcus and bartonella species were related to ANCA vasculitis-associated GN...
2017: Clin Nephrol Case Stud
https://www.readbyqxmd.com/read/29030859/outpatient-parenteral-antimicrobial-therapy-in-enterococcus-faecalis-infective-endocarditis
#5
M V Gil-Navarro, L E Lopez-Cortes, R Luque-Marquez, J Galvez-Acebal, A de Alarcon-Gonzalez
WHAT IS KNOWN AND OBJECTIVE: Enterococcus faecalis is the third most common causal agent of infective endocarditis. Currently, the treatment recommended is a combination of ampicillin (2 g/4 h) plus ceftriaxone (2 g/12 h), so patients must remain hospitalized for almost 6 weeks to receive the treatment. They are not generally included in outpatient parenteral antimicrobial therapy programs because 2 different electronic pumps are required to administer these 2 antibiotics. To enable the treatment of patients with E...
October 13, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28820551/fungal-endocarditis-due-to-aspergillus-oryzae-the-first-case-reported-in-the-literature
#6
Andrea Mazza, Nicola Luciani, Marco Luciani, Federico Cammertoni, Alessia Giaquinto, Natalia Pavone, Piergiorgio Bruno, Massimo Massetti
Infective endocarditis (IE) is a severe disease with high mortality and morbidity. Prosthetic valve endocarditis is a life-threatening complication which can occur in less than 10% of patients with valve prosthesis. A fungal etiology of IE is rare and accounts for only 2-4% of all case of endocarditis, but is associated with a higher mortality and morbidity. Herein is reported the first case of fungal endocarditis of aortic valve prosthesis due to Aspergillus oryzae in a 67-year-old caucasian man who nine years previously underwent mitral and aortic valve replacement with mechanical prostheses, and tricuspid annuloplasty for acute IE due to Enterococcus spp...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28811943/reviewing-the-emergence-of-lactococcus-garvieae-a-case-of-catheter-associated-urinary-tract-infection-caused-by-lactococcus-garvieae-and-escherichia-coli-coinfection
#7
Tatvam T Choksi, Farhan Dadani
Lactococcus garvieae is considered a low virulence organism which is rarely associated with human infections. Most of the reported cases have been associated with bacteremia with or without endocarditis. We report a rare case of catheter associated urinary tract infection (CAUTI) caused by Lactococcus garvieae and Escherichia coli coinfection without any bacteremia in a patient with indwelling urinary catheter placed for benign prostatic hyperplasia (BPH). The patient also had a history of gastroesophageal reflux disease (GERD) with long standing famotidine treatment...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28670302/prevalence-and-genetic-diversity-of-enterococcus-faecalis-isolates-from-mineral-water-and-spring-water-in-china
#8
Lei Wei, Qingping Wu, Jumei Zhang, Weipeng Guo, Moutong Chen, Liang Xue, Juan Wang, Lianying Ma
Enterococcus faecalis is an important opportunistic pathogen which is frequently detected in mineral water and spring water for human consumption and causes human urinary tract infections, endocarditis and neonatal sepsis. The aim of this study was to determine the prevalence, virulence genes, antimicrobial resistance and genetic diversity of E. faecalis from mineral water and spring water in China. Of 314 water samples collected from January 2013 to January 2014, 48 samples (15.3%) were contaminated E. faecalis...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28659548/pathogenicity-of-enterococci
#9
REVIEW
Yasuyoshi Ike
Enterococci belong to the group of lactic acid bacteria (LAB), and inhabit the gastrointestinal tracts of a wide variety of animals from insects and to human, and the commensal organism in humans and animals. The commensal/probiotic role of enterococci has evolved through thousands of years in mutual coexistence. Enterococcus have many favorable traits that have been appreciated in food fermentation and preservation, and many serve as probiotics to promote health. While lactobacillus have been shown to confer numerous benefits on and often regarded as health bringing organisms, enterococci have become more recognized as emerging human pathogens in recent years...
2017: Nihon Saikingaku Zasshi. Japanese Journal of Bacteriology
https://www.readbyqxmd.com/read/28648168/-mitral-valve-endocarditis-diagnosed-after-panophthalmitis-with-enterococcus-faecalis
#10
Kasper Kyhl, Peter Bomholt Hansen, Elin Holm, Torkil Á Steig, Rudi Kollslíð, Shahin Gaïni
An 86-year-old man underwent cataract surgery on the left eye, but suddenly he lost his vision three days after surgery. Topical treatments for panophthalmitis were started according to international guidelines. Later, a broad-range polymerase chain reaction showed Enterococcus faecalis in corpus vitreum, and IV antiobiotic treatment was initiated. To exclude endocarditis an echocardiography was performed, and this showed mitral regurgitation with a small mobile vegetation. Uncertainty concerning a possible causality between panophthalmitis and mitral valve endocarditis remains...
June 26, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28634536/telavancin-a-novel-semisynthetic-lipoglycopeptide-agent-to-counter-the-challenge-of-resistant-gram-positive-pathogens
#11
REVIEW
Biswadeep Das, Chayna Sarkar, Debasmita Das, Amit Gupta, Arnav Kalra, Shubham Sahni
Telavancin (TD-6424), a semisynthetic lipoglycopeptide vancomycin-derivative, is a novel antimicrobial agent developed by Theravance for overcoming resistant Gram-positive bacterial infections, specifically methicillin-resistant Staphylococcus aureus (MRSA). The US Food and Drug Administration (USFDA) had approved telavancin in 2009 for the treatment of complicated skin and skin structure infections (cSSSIs) caused by Gram-positive bacteria, including MRSA (S. aureus, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus anginosus group, or Enterococcus faecalis)...
March 2017: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/28590307/enterococcus-durans-endocarditis
#12
Mustafa Sunbul, Hatun O Cerik, Bugra Cerik, Okan Gulel, Hakan Leblebicioglu
No abstract text is available yet for this article.
May 22, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28567146/virulence-factors-associated-with-enterococcus-faecalis-infective-endocarditis-a-mini-review
#13
REVIEW
Kristian T Madsen, Marianne N Skov, Sabine Gill, Michael Kemp
INTRODUCTION: The enterococci are accountable for up to 20% of all cases of infective endocarditis, with Enterococcus faecalis being the primary causative isolate. Infective endocarditis is a life-threatening infection of the endocardium that results in the formation of vegetations. Based on a literature review, this paper provides an overview of the virulence factors associated with E. faecalis infective endocarditis. Furthermore, it reports the effects of active or passive immunization against some of these involved factors...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28521809/role-of-mitral-valve-repair-in-active-infective-endocarditis-long-term-results
#14
Carlo Rostagno, Enrico Carone, Pier Luigi Stefàno
BACKGROUND: Although mitral valve repair is at present the technique of choice in mitral regurgitation (MR) due to degenerative valve disease, long term results in patients with active mitral infective endocarditis (IE) are still under evaluation. METHODS: In the study were included 34 consecutive patients (22 males; mean age, 60 years; range 32-84 years) referred to our institution between January 1, 2005 to December 31, 2011 who were treated with valve repair for mitral valve (MV) active infective endocarditis...
May 18, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28482820/the-changing-epidemiology-and-clinical-features-of-infective-endocarditis-a-retrospective-study-of-196-episodes-in-a-teaching-hospital-in-china
#15
Wan Zhu, Qian Zhang, Jingping Zhang
BACKGROUND: Infective endocarditis is an uncommon but life-threatening infectious disease. To our knowledge, current investigations of the characteristics of infective endocarditis in our region are scarce. In this study, we aimed to investigate the changes in the epidemiology and clinical features of infective endocarditis. METHODS: A retrospective analysis of clinical data was performed using 196 infective endocarditis cases diagnosed between June 2004 and December 2012 at The First Affiliated Hospital of China Medical University...
May 8, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28439299/substance-p-enhances-lactic-acid-and-tyramine-production-in-enterococcus-faecalis-v583-and-promotes-its-cytotoxic-effect-on-intestinal-caco-2-tc7-cells
#16
Kelly Biaggini, Valérie Borrel, Sabine Szunerits, Rabah Boukherroub, Awa N'Diaye, Arthur Zébré, Maryse Bonnin-Jusserand, Guillaume Duflos, Marc Feuilloley, Djamel Drider, Pierre Déchelotte, Nathalie Connil
BACKGROUND: Enterococcus faecalis, generally considered as a saprophytic bowel commensal, has recently emerged as an important nosocomial pathogen causing severe urinary tract infections, surgical wound infections, bacteremia, and bacterial endocarditis. This bacterium is capable of forming biofilms on various surfaces and its high level of antibiotic resistance contributes to its pathogenicity. The aim of this study was to evaluate the effect on E. faecalis, of Substance P (SP), an antimicrobial peptide that is produced in the gut and skin...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28414678/what-the-eyes-don-t-see-the-heart-does-grieve-over
#17
M Sciaudone, M Dery
INTRODUCTION: A 71 year old Peruvian woman presented with blurry vision and bilateral eye pain and had evidence of bilateral endophthalmitis on eye examination. Her past medical history was notable for multiple abdominal surgeries within the preceding months, including an incarcerated inguinal hernia repair which required an ileostomy placement, and cholecystitis requiring cholecystostomy tube placement. Over her multiple long hospitalizations, she developed bacteremia and fungemia on several occasions, with organisms including Enterobacter cloacae, Klebsiella pneumoniae, Bacteroides fragilis, Pseudomonas aeruginosa, Enterococcus faecium, and Candida albicans...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28390740/a-predictive-model-for-early-mortality-after-surgical-treatment-of-heart-valve-or-prosthesis-infective-endocarditis-the-endoscore
#18
Michele Di Mauro, Guglielmo Mario Actis Dato, Fabio Barili, Sandro Gelsomino, Pasquale Santè, Alessandro Della Corte, Antonio Carrozza, Ester Della Ratta, Diego Cugola, Lorenzo Galletti, Roger Devotini, Riccardo Casabona, Francesco Santini, Antonio Salsano, Roberto Scrofani, Carlo Antona, Luca Botta, Claudio Russo, Samuel Mancuso, Mauro Rinaldi, Carlo De Vincentiis, Andrea Biondi, Cesare Beghi, Giangiuseppe Cappabianca, Vincenzo Tarzia, Gino Gerosa, Michele De Bonis, Alberto Pozzoli, Francesco Nicolini, Filippo Benassi, Francesco Rosato, Elena Grasso, Ugolino Livi, Sponga Sandro, Davide Pacini, Roberto Di Bartolomeo, Andrea De Martino, Uberto Bortolotti, Francesco Onorati, Giuseppe Faggian, Roberto Lorusso, Enrico Vizzardi, Gabriele Di Giammarco, Daniele Marinelli, Emmanuel Villa, Giovanni Troise, Marco Picichè, Francesco Musumeci, Domenico Paparella, Vito Margari, Francesco Tritto, Girolamo Damiani, Giuseppe Scrascia, Salvatore Zaccaria, Attilio Renzulli, Giuseppe Serraino, Giovanni Mariscalco, Daniele Maselli, Massimiliano Foschi, Alessandro Parolari, Giannantonio Nappi
BACKGROUND: The aim of this large retrospective study was to provide a logistic risk model along an additive score to predict early mortality after surgical treatment of patients with heart valve or prosthesis infective endocarditis (IE). METHODS: From 2000 to 2015, 2715 patients with native valve endocarditis (NVE) or prosthesis valve endocarditis (PVE) were operated on in 26 Italian Cardiac Surgery Centers. The relationship between early mortality and covariates was evaluated with logistic mixed effect models...
August 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28329161/surgery-for-prosthetic-valve-endocarditis-a-retrospective-study-of-a-national-registry
#19
Alessandro Della Corte, Michele Di Mauro, Guglielmo Actis Dato, Fabio Barili, Diego Cugola, Sandro Gelsomino, Pasquale Santè, Antonio Carozza, Ester Della Ratta, Lorenzo Galletti, Roger Devotini, Riccardo Casabona, Francesco Santini, Antonio Salsano, Roberto Scrofani, Carlo Antona, Carlo De Vincentiis, Andrea Biondi, Cesare Beghi, Giangiuseppe Cappabianca, Michele De Bonis, Alberto Pozzoli, Francesco Nicolini, Filippo Benassi, Davide Pacini, Roberto Di Bartolomeo, Andrea De Martino, Uberto Bortolotti, Roberto Lorusso, Enrico Vizzardi, Gabriele Di Giammarco, Daniele Marinelli, Emmanuel Villa, Giovanni Troise, Domenico Paparella, Vito Margari, Francesco Tritto, Girolamo Damiani, Giuseppe Scrascia, Salvatore Zaccaria, Attilio Renzulli, Giuseppe Serraino, Giovanni Mariscalco, Daniele Maselli, Alessandro Parolari, Giannantonio Nappi
OBJECTIVES: We described clinical-epidemiological features of prosthetic valve endocarditis (PVE) and assessed the determinants of early surgical outcomes in multicentre design. METHODS: Data regarding 2823 patients undergoing surgery for endocarditis at 19 Italian Centers between 1979 and 2015 were collected in a database. Of them, 582 had PVE: in this group, the determinants of early mortality and complications were assessed, also taking into account the different chronological eras encompassed by the study...
July 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28320712/efficacy-of-telavancin-alone-and-in-combination-with-ampicillin-in-a-rat-model-of-enterococcus-faecalis-endocarditis
#20
Truc T Tran, Vincent H Tam, Barbara E Murray, Cesar A Arias, Kavindra V Singh
We first assessed telavancin (TLV) pharmacokinetics in rats after a single subcutaneous dose of 35 mg/kg of body weight. The pharmacokinetic data were used to predict a TLV dose that simulates human exposure, and the efficacy of TLV was then evaluated using a TLV dose of 21 mg/kg every 12 h against Enterococcus faecalis OG1RF (TLV MIC of 0.06 μg/ml) in a rat endocarditis model with an indwelling catheter. Therapy was given for 3 days with TLV, daptomycin (DAP), or ampicillin (AMP) monotherapy and with combinations of TLV plus AMP, AMP plus gentamicin (GEN), and AMP plus ceftriaxone (CRO); rats were sacrificed 24 h after the last dose...
June 2017: Antimicrobial Agents and Chemotherapy
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