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Endocarditis enterococcus

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https://www.readbyqxmd.com/read/27916708/relationship-between-enterococcus-faecalis-infective-endocarditis-and-colorectal-neoplasm-preliminary-results-from-a-cohort-of-154-patients
#1
Juan M Pericàs, Juan Corredoira, Asunción Moreno, M José García-País, Carlos Falces, Ramón Rabuñal, Carlos A Mestres, M Pilar Alonso, Francesc Marco, Eduard Quintana, Manel Almela, Juan C Paré, Jaume Llopis, Antoni Castells, José M Miró
INTRODUCTION AND OBJECTIVES: The association between Streptococcus bovis group infective endocarditis and colorectal neoplasm (CRN) is well-known. However, no studies have assessed the association between Enterococcus faecalis infective endocarditis (EFIE) and CRN. We aimed to determine whether the prevalence of CRN is higher in patients with EFIE and an unclear source of infection than in patients with EFIE and a known source of infection or in the general population. METHODS: Retrospective analysis of a cohort of 154 patients with definite EFIE (109 with an unclear source of infection and 45 with an identified source) from 2 Spanish teaching hospitals to determine the prevalence of CRN and other colorectal diseases...
December 1, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27914083/antibody-guided-molecular-imaging-of-infective-endocarditis
#2
Kenneth L Pinkston, Peng Gao, Kavindra V Singh, Ali Azhdarinia, Barbara E Murray, Eva M Sevick-Muraca, Barrett R Harvey
In this protocol, we describe the application of using a high affinity monoclonal antibody generated against the major pilin protein component of the pilin structure of Enterococcus faecalis as a PET imaging agent for enterococcal endocarditis detection. The anti-pilin -mAb 64Cu conjugate was able to specifically label enterococcal endocarditis vegetation in vivo in a rodent endocarditis model. By targeting pili, a covalently linked surface antigen extending from the bacterial surface, we provided evidence that gram-positive pilin represent a logical surface antigen to define or target an infectious agent for molecularly guided imaging...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27904114/two-cases-of-proteinase-3-anti-neutrophil-cytoplasmic-antibody-pr3-anca-related-nephritis-in-infectious-endocarditis
#3
Kazuya Hirai, Naoto Miura, Masabumi Yoshino, Kanyu Miyamoto, Hironobu Nobata, Takuhito Nagai, Keisuke Suzuki, Shogo Banno, Hirokazu Imai
We herein report two cases of proteinase 3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)-related nephritis in infectious endocarditis. In both cases, the patients were middle-aged men with proteinuria and hematuria, hypoalbuminemia, decreased kidney function, anemia, elevated C-reactive protein (CRP) levels, and PR3-ANCA positivity. Each had bacteremia, due to Enterococcus faecium in one and Streptococcus bovis in the other. One patient received aortic valve replacement therapy for aortic regurgitation with vegetation, and the other underwent tricuspid valve replacement therapy and closure of a ventricular septic defect to treat tricuspid regurgitation with vegetation...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27891372/experience-with-splenic-abscess-from-southern-india
#4
Mallikarjuna Shetty, Swaroopa Deme, Knkj Mohan, Krishna Prasad Adiraju, Nageswar Rao Modugu, Naval Chandra, Amvr Narendra, Sathyanarayana Raju Yadati
INTRODUCTION: Splenic abscess is a rare entity with potentially life threatening complications. Sparse recent published data are available documenting the aetiological profile and management of patients with splenic abscess from India. AIM: To study the clinical profile of splenic abscess. MATERIALS AND METHODS: We retrospectively collected data from case records of admitted patients with splenic abscesses, to Nizam's Institute of Medical Sciences and Hospital which is a multispecialty, tertiary care referral hospital over a period of 15 months (from March 2014 to May 2015) and parameters studied were age, sex, symptoms, signs, risk factors, investigations like Ultrasound, CT scan, blood & microbiological culture, treatment and outcome...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27797843/endocarditis-and-monocular-blindness
#5
Jack Andrews, Shyamanga Borooah
A man aged 77 years with postrenal transplant lymphoproliferative disease was admitted with high fever, elevated inflammatory markers and a heart murmur. Blood cultures grew Enterococcus faecalis and he was found to have mitral valve endocarditis on echocardiogram and subsequently started on appropriate antibiotics. 5 days into treatment, he developed ocular symptoms and 3 days later, he had irreversible monocular visual loss. He was seen by the ophthalmology team who diagnosed endogenous endopthalmitis secondary to bacteraemic spread from his endocarditis...
October 26, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27795476/a-decennium-of-etiology-and-antimicrobial-susceptibility-patterns-in-patients-with-infective-endocarditis-at-a-university-hospital-thailand
#6
Chotirat Nakaranurack, Chankit Puttilerpong, Gompol Suwanpimolkul
Infective endocarditis is an infection with a high mortality rate. Antimicrobial therapy is important in treatment but data on antimicrobial susceptibilities are limited. This retrospective study analyzed the data of causative microorganisms and antimicrobial susceptibility patterns in patients with infective endocarditis who were aged 18 years or older and received inpatient care between 2006 and 2015 at King Chulalongkorn Memorial Hospital. A total of 213 patients fulfilled the inclusion criteria. Streptococcus spp...
October 31, 2016: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27689100/daptomycin-vancomycin-resistant-enterococcus-faecium-native-valve-endocarditis-successfully-treated-with-off-label-quinupristin-dalfopristin
#7
Khandakar Hussain, Saad Ullah, Hassan Tahir, Waseem Zaid Alkilani, Muhammad Naeem, Nagadarshini Ramagiri Vinod, Samuel Massoud
Multidrug-resistant enterococcal nosocomial invasive infections are a rising concern faced by the medical community. Not many options are available to treat these highly virulent organisms. Risk factors for developing these highly resistant organisms include prolonged hospital stay, previous antibiotic use, and immunosuppression. In this article, we report a case of daptomycin-resistant enterococcal native infective endocarditis treated with off-label use of quinupristin-dalfopristin.
July 2016: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/27629895/comparison-of-pcr-electrospray-ionization-mass-spectrometry-with-16s-rrna-pcr-and-amplicon-sequencing-for-detection-of-bacteria-in-excised-heart-valves
#8
Bart Peeters, Paul Herijgers, Kurt Beuselinck, Willy E Peetermans, Marie-Christin Herregods, Stefanie Desmet, Katrien Lagrou
Identification of the causative pathogen of infective endocarditis is crucial for adequate management and therapy. A broad range PCR/electrospray ionization mass spectrometry (PCR/ESI-MS) technique was compared with broad-spectrum 16S rRNA PCR and amplicon sequencing (16S rRNA PCR) for detecting bacterial pathogens in 40 heart valves obtained from 34 definite infective endocarditis patients according to the modified Duke Criteria and six non-endocarditis patients. Concordance between both molecular techniques was 98% for being positive or negative, 97% for concordant identification up to genus level and 77% for concordant identification up to species level...
September 14, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27617012/dispersion-of-the-vancomycin-resistance-genes-vana-and-vanc-of-enterococcus-isolated-from-nile-tilapia-on-retail-sale-a-public-health-hazard
#9
Kamelia M Osman, Mohamed N Ali, Ismail Radwan, Fatma ElHofy, Ahmed H Abed, Ahmed Orabi, Nehal M Fawzy
Although normally regarded harmless commensals, enterococci may cause a range of different infections in humans, including urinary tract infections, sepsis, and endocarditis. The acquisition of vancomycin resistance by enterococci (VRE) has seriously affected the treatment and infection control of these organisms. VRE are frequently resistant to all antibiotics that are effective treatment for vancomycin-susceptible enterococci, which leaves clinicians treating VRE infections with limited therapeutic options...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27523465/enterococcus-durans-prosthetic-valve-endocarditis-a-previously-unreported-clinical-entity
#10
Alkesh Zala, Nicholas Collins
No abstract text is available yet for this article.
October 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27500132/prosthetic-aortic-valve-endocarditis-with-left-main-coronary-artery-embolism-a-case-report-and-review-of-the-literature
#11
Hafeez Ul Hassan Virk, Faisal Inayat, Salman Farooq, Ali Raza Ghani, Ghazi A Mirrani, Muhammed Waqas Athar
CONTEXT: Coronary embolization is potentially a fatal sequela of endocarditis. Although the primary cause of acute coronary syndrome is atherosclerotic disease, it is imperative to consider septic embolism as an etiological factor. CASE REPORT: Herein, we report a case of ventricular fibrillation and ST-segment depression myocardial infarction occurring in a patient who initially presented with fever and increased urinary frequency. Coronary angiography revealed new 99% occlusion of the left main coronary artery (LMCA)...
June 2016: North American Journal of Medical Sciences
https://www.readbyqxmd.com/read/27488025/daptomycin-for-the-treatment-of-major-gram-positive-infections-after-cardiac-surgery
#12
A Kornberger, B Luchting, F Kur, M Weis, F Weis, U A Stock, A Beiras-Fernandez
BACKGROUND: Infection is a main cause of morbidity and mortality after heart surgery, with multi-resistant pathogens increasingly representing a challenge. Daptomycin provides bactericidal activity against gram-positive organisms that are resistant to standard treatment including vancomycin. METHODS: A cohort of cardiac surgical patients, treated with daptomycin for major infection at two tertiary care centers, were retrospectively studied with a particular focus on the type of infection, causative pathogens and co-infections, daptomycin dosage, adverse events and outcome in order to provide evidence for the efficiency and safety of daptomycin in a distinct high-risk patient population...
August 4, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27464216/colorectal-adenomas
#13
LETTER
Ester Castellsagué, Barbara Rivera, William D Foulkes
No abstract text is available yet for this article.
July 28, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27464215/colorectal-adenomas
#14
LETTER
Steven H Itzkowitz, David A Ahlquist
No abstract text is available yet for this article.
July 28, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27464214/colorectal-adenomas
#15
LETTER
Juan M Pericàs, Juan Corredoira, José M Miró
No abstract text is available yet for this article.
July 28, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27464213/colorectal-adenomas
#16
LETTER
Williamson B Strum
No abstract text is available yet for this article.
July 28, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27463203/new-insights-into-the-enterococcus-faecium-and-streptococcus-gallolyticus-subsp-gallolyticus-host-interaction-mechanisms
#17
Ana María Sánchez-Díaz, Beatriz Romero-Hernández, Elisa Conde-Moreno, Young-Keun Kwak, Javier Zamora, Patricia Colque-Navarro, Roland Möllby, Patricia Ruiz-Garbajosa, Rafael Cantón, Laura García-Bermejo, Rosa Del Campo
Enterococcus faecium and Streptococcus gallolyticus subsp. gallolyticus (S. gallolyticus) were classically clustered into the Lancefield Group D streptococci and despite their taxonomic reclassification still share a similar genetic content and environment. Both species are considered as opportunistic pathogens. E. faecium is often associated with nosocomial bacteraemia, and S. gallolyticus is sporadically found in endocarditis of colorectal cancer patients. In both cases, the source of infection is commonly endogenous with a translocation process that launches through the intestinal barrier...
2016: PloS One
https://www.readbyqxmd.com/read/27460295/bacteremia-due-to-streptococcus-tigurinus-a-case-report-and-literature-review
#18
Jun Hirai, Daisuke Sakanashi, Mao Hagihara, Shusaku Haranaga, Kohei Uechi, Hideo Kato, Hiroyuki Hamada, Naoya Nishiyama, Yusuke Koizumi, Hiroyuki Suematsu, Yuka Yamagishi, Jiro Fujita, Hiroshige Mikamo
Gene sequence analysis methods, including 16S rRNA identification, allows accurate identification of Streptococcus species, which include phenotypically closely related species that are difficult to differentiate using conventional chemical methods. We report a case of bacteremia due to Streptococcus tigurinus, identified by 16S rRNA, in a 72-year-old woman with gastrointestinal cancer and ascites. She was hospitalized to undergo elective tumor-related surgery. Five days prior to undergoing surgery, she developed a fever with no obvious source of infection...
July 23, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/27391962/bacteraemia-during-transurethral-resection-of-the-prostate-what-are-the-risk-factors-and-is-it-more-common-than-we-think
#19
Amar Raj Mohee, Deborah Gascoyne-Binzi, Robert West, Selina Bhattarai, Ian Eardley, Jonathan A T Sandoe
The aim of this work was to investigate the microbial causes, incidence, duration, risk factors and clinical implications of bacteraemia occurring during transurethral resection of the prostate (TURP) surgery to better inform prophylaxis strategies. An ethically approved, prospective, cohort study of patients undergoing TURP was conducted. Clinical information and follow-up details were collected using standardized data collection sheets. Blood was obtained for culture at 6 different time points peri-procedure...
2016: PloS One
https://www.readbyqxmd.com/read/27374863/a-case-of-infective-endocarditis-and-pyogenic-spondylitis-after-transrectal-ultrasound-guided-prostate-biopsy
#20
Yoshiki Hiyama, Satoshi Takahashi, Teruhisa Uehara, Koji Ichihara, Jiro Hashimoto, Naoya Masumori
We report a patient with infective endocarditis and pyrogenic spondylitis occurring simultaneously. The patient was a 59-year-old man. He was suspected of having prostate cancer due to a high prostate-specific antigen concentration noted in a checkup. He then underwent a transrectal ultrasound guided prostate biopsy with cefotiam as antimicrobial prophylaxis. He had a fever higher than 38 °C and lumbar pain for a few days after the biopsy. Enterococcus faecalis was isolated from 2 sets of blood culture. Magnetic resonance imaging revealed an abnormal image at C7/Th1 with a signal decrease in T1-weighted sequences and signal increase in T2-weighted sequences that were suspected to be due to bone destruction...
June 28, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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