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Chronic obsructive pulmonary disease

Zafar Zafari, Kristian Thorlund, J Mark FitzGerald, Carlo A Marra, Mohsen Sadatsafavi
OBJECTIVE: To evaluate the impact of using two evidence-synthesis paradigms, pairwise meta-analysis (PMA) vs. network meta-analysis (NMA), on the expected value of information (EVI) outcomes, using pharmacotherapy of chronic obstructive pulmonary disease as a case study. METHODS: Bayesian random-effects PMAs were performed for each pharmacotherapy vs. placebo, and a Bayesian random-effects NMA was performed combining both placebo-controlled and head-to-head trials...
October 2014: PharmacoEconomics
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