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https://www.readbyqxmd.com/read/29872338/morning-blood-pressure-surge-pathophysiology-clinical-relevance-and-therapeutic-aspects
#1
REVIEW
Grzegorz Bilo, Andrea Grillo, Valentina Guida, Gianfranco Parati
Morning hours are the period of the day characterized by the highest incidence of major cardiovascular events including myocardial infarction, sudden death or stroke. They are also characterized by important neurohormonal changes, in particular, the activation of sympathetic nervous system which usually leads to a rapid increase in blood pressure (BP), known as morning blood pressure surge (MBPS). It was hypothesized that excessive MBPS may be causally involved in the pathogenesis of cardiovascular events occurring in the morning by inducing hemodynamic stress...
2018: Integrated Blood Pressure Control
https://www.readbyqxmd.com/read/29848864/-thermal-and-lighting-housing-environments-and-circadian-blood-pressure-variability-findings-from-the-heijo-kyo-cohort
#2
Kenji Obayashi, Keigo Saeki
The purpose of this short review is to describe the influence of housing environment temperature and lighting on circadian blood pressure (BP) variability using data from the HEIJO-KYO cohort, a community-based cohort study launched in 2010. Increased excess mortality from cardiovascular disease in winter is a worldwide problem. Previous studies showed higher conventional BP and higher daytime ambulatory BP in winter; however, the relationship between indoor cold exposure and circadian BP variability remained unknown...
2018: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
https://www.readbyqxmd.com/read/29800067/association-of-cardiovascular-outcomes-with-masked-hypertension-defined-by-home-blood-pressure-monitoring-in-a-japanese-general-practice-population
#3
Takeshi Fujiwara, Yuichiro Yano, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario
Importance: The clinical outcomes associated with masked hypertension defined by home blood pressure monitoring (HBPM) in clinical settings remain uncertain. Objective: To assess the association between masked hypertension and cardiovascular disease events in clinical settings. Design, Setting, and Participants: This observational cohort study used data from 4261 outpatients treated at 71 primary practices or university hospitals throughout Japan who were enrolled in the Japan Morning Surge-Home Blood Pressure study between January 1, 2005, and December 31, 2012...
May 23, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29790794/association-of-morning-blood-pressure-surge-with-carotid-intima-media-thickness-and-cardiac-dysfunction-in-patients-with-cardiac-syndrome-x
#4
Ragab A Mahfouz, Mohammad Goda, Islam Galal, Mohamed S Ghareb
Background & hypothesis: We hypothesized that exaggerated morning blood pressure surge, may contribute in cardiac dysfunction and arterial stiffness in patients with cardiac syndrome X. Thus we investigated the impact of morning blood pressure surge on cardiac function and carotid intima-media thickness in subjects with cardiac syndrome X. METHODS: We studied patients with cardiac syndrome X using ambulatory blood pressure monitoring and investigated the association of morning blood pressure surge with carotid intima thickness, left atrial volume index and left ventricular filling (E/e')...
May 23, 2018: Blood Pressure
https://www.readbyqxmd.com/read/29790788/no-association-of-moon-phase-with-stroke-occurrence
#5
Jori O Ruuskanen, Jussi O T Sipilä, Päivi Rautava, Ville Kytö
Stroke occurrence shows strong correlations with sleep disorders and even subtle sleep disturbances have been shown to affect ischemic stroke (IS) occurrence. Chronobiology also exerts effects, like the morning surge in IS occurrence. Lunar cycles have also been shown to affect sleep and other physiological processes, but studies on moon phases and its possible association with occurrence of stroke are rare and nonconclusive. Therefore, we studied the effects of moon phases on stroke hospitalizations and in-hospital mortality nationwide in Finland in 2004-2014...
May 23, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29789641/diurnal-blood-pressure-changes
#6
REVIEW
Kei Asayama, Michihiro Satoh, Masahiro Kikuya
The definition of diurnal blood pressure changes varies widely, which can be confusing. Short-term blood pressure variability during a 24-h period and the dipping status of diurnal blood pressure can be captured by ambulatory blood pressure monitoring, and these metrics are reported to have prognostic significance for cardiovascular complications. Morning blood pressure surge also indicates this risk, but its effect may be limited to populations with specific conditions. Meanwhile, the combined use of conventional office blood pressure and out-of-office blood pressure allows us to identify people with white-coat and masked hypertension...
May 23, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29738355/morning-blood-pressure-surge-is-associated-independently-with-orthostatic-hypotension-in-hypertensive-patients-under-treatment
#7
Hakan Caf, Yurdaer Dönmez, Emel Çeliker Güler, Onur Kaypakli, Yahya Kemal İçen, Mevlüt Koç
OBJECTIVE: Morning blood pressure surge (MBPS) and orthostatic hypotension (OH) play a role in the occurrence of cardiovascular events. We aimed to investigate the association between MBPS and OH in hypertensive patients under treatment. PATIENTS AND METHODS: We prospectively included 297 patients (mean age: 53.8±10.7 years, male/female: 101/196) with essential hypertension. Tilt table testing was performed for the diagnosis of OH. OH was classified into three groups as initial OH (0-15 s), classical OH (15 s to 3 min), and delayed OH (3-30 min)...
May 7, 2018: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29605539/integrated-flow-mediated-vasodilation-response-predicts-cardiovascular-events-in-elderly-patients-with-cardiovascular-risk-factors-the-japan-morning-surge-home-blood-pressure-study
#8
Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario
The integrated flow-mediated vasodilation (FMD) response has been associated with cardiovascular (CV) risk factors, but the association between the integrated FMD response and subsequent CV events has been unclear. We enrolled 555 patients who had at least one CV risk factor (hypertension, dyslipidemia, diabetes, or smoking). We measured the peak percentage change in diameter (ΔFMD), and integrated FMD response calculated as the area under the dilation curve over a 120-second dilation period (FMD-AUC120 )...
May 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29536281/there-is-a-significant-relationship-between-morning-blood-pressure-surge-and-increased-abdominal-aortic-intima-media-thickness-in-hypertensive-patients
#9
Ayse Selcan Koc, Ferıde Fatma Gorgulu, Yurdaer Donmez, Yahya Kemal Icen
PURPOSE: There are limited data about increased aortic intima-media thickness (A-IMT) in the presence of subclinical target organ damage in hypertensive (HT) patients. In this study, we aimed to determine the frequency of increased A-IMT, the parameters determining increased A-IMT, and the relationship between increased A-IMT and other vascular IMT measurements. MATERIALS AND METHODS: We prospectively included 265 patients (mean age 54.1 ± 10.6 years, male/female 91/174) with essential HT...
March 13, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29489529/finding-the-fertile-phase-low-cost-luteinizing-hormone-sticks-versus-electronic-fertility-monitor
#10
Mary Lee Barron, Kaitlin Vanderkolk, Kathleen Raviele
PURPOSE: To investigate if generic Wondfo ovulation sticks (WLH) are sufficiently sensitive to the luteinizing hormone (LH) surge in urine when used with the Marquette Fertility Algorithm. The electronic hormonal fertility monitor (EHFM) is highly accurate in detecting the LH surge but cost of the monitor and the accompanying test sticks has increased over the last several years. The EHFM is sensitive to detect the LH surge at 20 milli-international units per milliliter (mIU/mL); the WLH sticks are slightly less sensitive at 25 mIU/mL...
May 2018: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/29450967/carotid-atherosclerosis-and-the-association-between-nocturnal-blood-pressure-dipping-and-cardiovascular-events
#11
Praew Kotruchin, Satoshi Hoshide, Kazuomi Kario
The impact of a nondipping blood pressure (BP) pattern, defined as (awake systolic BP - sleep systolic BP)/awake systolic BP < 0.1, on cardiovascular events in populations with different degrees of carotid atherosclerosis is uncertain. The authors hypothesized that a nondipping BP pattern would show differential predictive power for cardiovascular events, including total cardiovascular death, sudden death, nonfatal cardiovascular events, and nonfatal stroke, between populations with and without carotid atherosclerosis...
March 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29385702/altered-circadian-timing-system-mediated-non-dipping-pattern-of-blood-pressure-and-associated-cardiovascular-disorders-in-metabolic-and-kidney-diseases
#12
REVIEW
Asadur Rahman, Arif Ul Hasan, Akira Nishiyama, Hiroyuki Kobori
The morning surge in blood pressure (BP) coincides with increased cardiovascular (CV) events. This strongly suggests that an altered circadian rhythm of BP plays a crucial role in the development of CV disease (CVD). A disrupted circadian rhythm of BP, such as the non-dipping type of hypertension (i.e., absence of nocturnal BP decline), is frequently observed in metabolic disorders and chronic kidney disease (CKD). The circadian timing system, controlled by the central clock in the suprachiasmatic nucleus of the hypothalamus and/or by peripheral clocks in the heart, vasculature, and kidneys, modulates the 24 h oscillation of BP...
January 30, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29380730/hurry-up-it-s-quiet-in-the-emergency-department
#13
E Ter Avest, B T Onnes, T van der Vaart, M J Land
INTRODUCTION: Emergency department (ED) crowding is a contemporary problem. Solutions are multiple, but often involve a lengthy implementation process and/or substantial funding. Therefore, it is important that in the meanwhile, we aim to identify simple strategies, focussing on optimising efficiency of the available resources, which can be adopted in the ED here and now. METHODS: We made a careful analysis of inflow, throughput and outflow data of all 24,823 patients visiting the ED of a large teaching hospital in the year 2015, and looked in more detail at the 10 days with the longest average throughput times...
January 2018: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/29380409/morning-surge-in-blood-pressure-using-a-random-effects-multiple-component-cosinor-model
#14
J M Madden, L D Browne, X Li, P M Kearney, A P Fitzgerald
Blood pressure (BP) fluctuates throughout the day. The pattern it follows represents one of the most important circadian rhythms in the human body. For example, morning BP surge has been suggested as a potential risk factor for cardiovascular events occurring in the morning, but the accurate quantification of this phenomenon remains a challenge. Here, we outline a novel method to quantify morning surge. We demonstrate how the most commonly used method to model 24-hour BP, the single cosinor approach, can be extended to a multiple-component cosinor random-effects model...
May 10, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29338119/management-of-morning-hypertension-a-consensus-statement-of-an-asian-expert-panel
#15
REVIEW
Ji-Guang Wang, Kazuomi Kario, Chen-Huan Chen, Jeong-Bae Park, Satoshi Hoshide, Yong Huo, Hae-Young Lee, Yan Li, Masaki Mogi, Masanori Munakata, Sungha Park, Dingliang Zhu
Morning blood pressure (BP) surge is an important aspect of hypertension research. Morning BP monitoring could be a clinically relevant concept in the therapeutic management of hypertension and in the prevention of cardiovascular complications by defining and treating morning hypertension. Because antihypertensive medication is often taken in the morning, uncontrolled morning BP during the trough effect hours could be a hallmark of inadequate choice of antihypertensive regimen, such as the use of short- or intermediate-acting drugs, underdosing of drugs, or no use or underuse of combination therapy...
January 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316213/comparative-effects-of-valsartan-plus-either-cilnidipine-or-hydrochlorothiazide-on-home-morning-blood-pressure-surge-evaluated-by-information-and-communication-technology-based-nocturnal-home-blood-pressure-monitoring
#16
Takeshi Fujiwara, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario
The authors tested the hypothesis that a valsartan/cilnidipine combination would suppress the home morning blood pressure (BP) surge (HMBPS) more effectively than a valsartan/hydrochlorothiazide combination in patients with morning hypertension, defined as systolic BP (SBP) ≥135 mm Hg or diastolic BP ≥85 mm Hg assessed by a self-measuring information and communication technology-based home BP monitoring device more than three times before either combination's administration. This was an 8-week prospective, multicenter, randomized, open-label clinical trial...
January 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29223957/prognostic-utility-of-morning-blood-pressure-surge-for-20-year-all-cause-and-cardiovascular-mortalities-results-of-a-community-based-study
#17
Hao-Min Cheng, Chung-Li Wu, Shih-Hsien Sung, Jia-Chun Lee, Kazuomi Kario, Chern-En Chiang, Chi-Jung Huang, Pai-Feng Hsu, Shao-Yuan Chuang, Edward G Lakatta, Frank C P Yin, Pesus Chou, Chen-Huan Chen
BACKGROUND: Morning blood pressure (BP) surge (MS), defined by the MS amplitude, is an independent prognostic factor of cardiovascular outcomes in some, but not all, populations. METHOD AND RESULTS: We enrolled 2020 participants (1029 men; aged 30-79 years) with 24-hour ambulatory BP data. During a median 19.7-year follow-up, 607 deaths (182 by cardiovascular causes) were confirmed from the National Death Registry. The amplitude of sleep-trough MS (STMS) was derived from the difference between morning systolic BP (SBP) and lowest nighttime SBP...
December 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29153058/induction-of-the-lh-surge-in-premenarchal-girls-confirms-early-maturation-of-the-hypothalamic-pituitary-ovarian-axis
#18
Polina Rovner, Julia Keltz, Amanda Allshouse, Barbara Isaac, Cheryl Hickmon, Jennifer Lesh, Justin Chosich, Nanette Santoro
PURPOSE: To determine whether premenarchal girls exhibit positive estradiol feedback similar to regularly cycling adult women when given exogenous estradiol. METHODS: This was a prospective clinical cohort study at 2 institutions. Nine girls and 6 women received a 7-day course of transdermal estradiol designed to produce physiologic, mid-cycle circulating estradiol levels. Participants collected daily morning urine for luteinizing hormone (LH), estradiol metabolites (E1c), and progesterone metabolites (Pdg), corrected for creatinine...
January 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29133364/day-by-day-variability-of-home-blood-pressure-and-incident-cardiovascular-disease-in-clinical-practice-the-j-hop-study-japan-morning-surge-home-blood-pressure
#19
Satoshi Hoshide, Yuichiro Yano, Hiroyuki Mizuno, Hiroshi Kanegae, Kazuomi Kario
We assessed the relationship between day-by-day home blood pressure (BP) variability and incident cardiovascular disease (CVD) in clinical practice. J-HOP study (Japan Morning Surge-Home Blood Pressure) participants underwent home BP monitoring in the morning and evening for a 14-day period, and their BP levels and BP variability independent of the mean (VIM) were assessed. Incident CVD events included coronary heart disease and stroke. Cox models were fitted to assess the home BP variability-CVD risk association...
January 2018: Hypertension
https://www.readbyqxmd.com/read/28956652/association-between-sleep-disorders-and-morning-blood-pressure-in-hypertensive-patients
#20
Xinran Li, Jiangbo Li, Kai Liu, Shenzhen Gong, Rufeng Shi, Pei Pan, Yujie Yang, Xiaoping Chen
Sleep disorders are known to increase the risk of hypertension, yet few studies have investigated the relation between sleep disorders and morning blood pressure (BP). This study aimed to determine, whether the morning BP is associated with sleep quality and sleep-disordered breathing. A total of 144 hypertensive patients were included in this cross-sectional study. Each subject underwent anthropometric measurements, biochemical testing, 24-h ambulatory BP monitoring, and polysomnography (PSG). Sleep quality and sleep-disordered breathing were determined by PSG parameters of sleep architecture and sleep respiratory...
2018: Clinical and Experimental Hypertension: CHE
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