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https://www.readbyqxmd.com/read/29605539/integrated-flow-mediated-vasodilation-response-predicts-cardiovascular-events-in-elderly-patients-with-cardiovascular-risk-factors-the-japan-morning-surge-home-blood-pressure-study
#1
Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario
The integrated flow-mediated vasodilation (FMD) response has been associated with cardiovascular (CV) risk factors, but the association between the integrated FMD response and subsequent CV events has been unclear. We enrolled 555 patients who had at least one CV risk factor (hypertension, dyslipidemia, diabetes, or smoking). We measured the peak percentage change in diameter (ΔFMD), and integrated FMD response calculated as the area under the dilation curve over a 120-second dilation period (FMD-AUC120 )...
March 21, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29536281/there-is-a-significant-relationship-between-morning-blood-pressure-surge-and-increased-abdominal-aortic-intima-media-thickness-in-hypertensive-patients
#2
Ayse Selcan Koc, Ferıde Fatma Gorgulu, Yurdaer Donmez, Yahya Kemal Icen
PURPOSE: There are limited data about increased aortic intima-media thickness (A-IMT) in the presence of subclinical target organ damage in hypertensive (HT) patients. In this study, we aimed to determine the frequency of increased A-IMT, the parameters determining increased A-IMT, and the relationship between increased A-IMT and other vascular IMT measurements. MATERIALS AND METHODS: We prospectively included 265 patients (mean age 54.1 ± 10.6 years, male/female 91/174) with essential HT...
March 13, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29489529/finding-the-fertile-phase-low-cost-luteinizing-hormone-sticks-versus-electronic-fertility-monitor
#3
Mary Lee Barron, Kaitlin Vanderkolk, Kathleen Raviele
PURPOSE: To investigate if generic Wondfo ovulation sticks (WLH) are sufficiently sensitive to the luteinizing hormone (LH) surge in urine when used with the Marquette Fertility Algorithm. The electronic hormonal fertility monitor (EHFM) is highly accurate in detecting the LH surge but cost of the monitor and the accompanying test sticks has increased over the last several years. The EHFM is sensitive to detect the LH surge at milli-international units per milliliter (mIU/mL); the WLH sticks are slightly less sensitive at 25 mIU/mL...
February 27, 2018: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/29450967/carotid-atherosclerosis-and-the-association-between-nocturnal-blood-pressure-dipping-and-cardiovascular-events
#4
Praew Kotruchin, Satoshi Hoshide, Kazuomi Kario
The impact of a nondipping blood pressure (BP) pattern, defined as (awake systolic BP - sleep systolic BP)/awake systolic BP < 0.1, on cardiovascular events in populations with different degrees of carotid atherosclerosis is uncertain. The authors hypothesized that a nondipping BP pattern would show differential predictive power for cardiovascular events, including total cardiovascular death, sudden death, nonfatal cardiovascular events, and nonfatal stroke, between populations with and without carotid atherosclerosis...
February 16, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29385702/altered-circadian-timing-system-mediated-non-dipping-pattern-of-blood-pressure-and-associated-cardiovascular-disorders-in-metabolic-and-kidney-diseases
#5
REVIEW
Asadur Rahman, Arif Ul Hasan, Akira Nishiyama, Hiroyuki Kobori
The morning surge in blood pressure (BP) coincides with increased cardiovascular (CV) events. This strongly suggests that an altered circadian rhythm of BP plays a crucial role in the development of CV disease (CVD). A disrupted circadian rhythm of BP, such as the non-dipping type of hypertension (i.e., absence of nocturnal BP decline), is frequently observed in metabolic disorders and chronic kidney disease (CKD). The circadian timing system, controlled by the central clock in the suprachiasmatic nucleus of the hypothalamus and/or by peripheral clocks in the heart, vasculature, and kidneys, modulates the 24 h oscillation of BP...
January 30, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29380730/hurry-up-it-s-quiet-in-the-emergency-department
#6
E Ter Avest, B T Onnes, T van der Vaart, M J Land
INTRODUCTION: Emergency department (ED) crowding is a contemporary problem. Solutions are multiple, but often involve a lengthy implementation process and/or substantial funding. Therefore, it is important that in the meanwhile, we aim to identify simple strategies, focussing on optimising efficiency of the available resources, which can be adopted in the ED here and now. METHODS: We made a careful analysis of inflow, throughput and outflow data of all 24,823 patients visiting the ED of a large teaching hospital in the year 2015, and looked in more detail at the 10 days with the longest average throughput times...
January 2018: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/29380409/morning-surge-in-blood-pressure-using-a-random-effects-multiple-component-cosinor-model
#7
J M Madden, L D Browne, X Li, P M Kearney, A P Fitzgerald
Blood pressure (BP) fluctuates throughout the day. The pattern it follows represents one of the most important circadian rhythms in the human body. For example, morning BP surge has been suggested as a potential risk factor for cardiovascular events occurring in the morning, but the accurate quantification of this phenomenon remains a challenge. Here, we outline a novel method to quantify morning surge. We demonstrate how the most commonly used method to model 24-hour BP, the single cosinor approach, can be extended to a multiple-component cosinor random-effects model...
January 29, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29338119/management-of-morning-hypertension-a-consensus-statement-of-an-asian-expert-panel
#8
REVIEW
Ji-Guang Wang, Kazuomi Kario, Chen-Huan Chen, Jeong-Bae Park, Satoshi Hoshide, Yong Huo, Hae-Young Lee, Yan Li, Masaki Mogi, Masanori Munakata, Sungha Park, Dingliang Zhu
Morning blood pressure (BP) surge is an important aspect of hypertension research. Morning BP monitoring could be a clinically relevant concept in the therapeutic management of hypertension and in the prevention of cardiovascular complications by defining and treating morning hypertension. Because antihypertensive medication is often taken in the morning, uncontrolled morning BP during the trough effect hours could be a hallmark of inadequate choice of antihypertensive regimen, such as the use of short- or intermediate-acting drugs, underdosing of drugs, or no use or underuse of combination therapy...
January 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29316213/comparative-effects-of-valsartan-plus-either-cilnidipine-or-hydrochlorothiazide-on-home-morning-blood-pressure-surge-evaluated-by-information-and-communication-technology-based-nocturnal-home-blood-pressure-monitoring
#9
Takeshi Fujiwara, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario
The authors tested the hypothesis that a valsartan/cilnidipine combination would suppress the home morning blood pressure (BP) surge (HMBPS) more effectively than a valsartan/hydrochlorothiazide combination in patients with morning hypertension, defined as systolic BP (SBP) ≥135 mm Hg or diastolic BP ≥85 mm Hg assessed by a self-measuring information and communication technology-based home BP monitoring device more than three times before either combination's administration. This was an 8-week prospective, multicenter, randomized, open-label clinical trial...
January 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29223957/prognostic-utility-of-morning-blood-pressure-surge-for-20-year-all-cause-and-cardiovascular-mortalities-results-of-a-community-based-study
#10
Hao-Min Cheng, Chung-Li Wu, Shih-Hsien Sung, Jia-Chun Lee, Kazuomi Kario, Chern-En Chiang, Chi-Jung Huang, Pai-Feng Hsu, Shao-Yuan Chuang, Edward G Lakatta, Frank C P Yin, Pesus Chou, Chen-Huan Chen
BACKGROUND: Morning blood pressure (BP) surge (MS), defined by the MS amplitude, is an independent prognostic factor of cardiovascular outcomes in some, but not all, populations. METHOD AND RESULTS: We enrolled 2020 participants (1029 men; aged 30-79 years) with 24-hour ambulatory BP data. During a median 19.7-year follow-up, 607 deaths (182 by cardiovascular causes) were confirmed from the National Death Registry. The amplitude of sleep-trough MS (STMS) was derived from the difference between morning systolic BP (SBP) and lowest nighttime SBP...
December 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29153058/induction-of-the-lh-surge-in-premenarchal-girls-confirms-early-maturation-of-the-hypothalamic-pituitary-ovarian-axis
#11
Polina Rovner, Julia Keltz, Amanda Allshouse, Barbara Isaac, Cheryl Hickmon, Jennifer Lesh, Justin Chosich, Nanette Santoro
PURPOSE: To determine whether premenarchal girls exhibit positive estradiol feedback similar to regularly cycling adult women when given exogenous estradiol. METHODS: This was a prospective clinical cohort study at 2 institutions. Nine girls and 6 women received a 7-day course of transdermal estradiol designed to produce physiologic, mid-cycle circulating estradiol levels. Participants collected daily morning urine for luteinizing hormone (LH), estradiol metabolites (E1c), and progesterone metabolites (Pdg), corrected for creatinine...
January 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29133364/day-by-day-variability-of-home-blood-pressure-and-incident-cardiovascular-disease-in-clinical-practice-the-j-hop-study-japan-morning-surge-home-blood-pressure
#12
Satoshi Hoshide, Yuichiro Yano, Hiroyuki Mizuno, Hiroshi Kanegae, Kazuomi Kario
We assessed the relationship between day-by-day home blood pressure (BP) variability and incident cardiovascular disease (CVD) in clinical practice. J-HOP study (Japan Morning Surge-Home Blood Pressure) participants underwent home BP monitoring in the morning and evening for a 14-day period, and their BP levels and BP variability independent of the mean (VIM) were assessed. Incident CVD events included coronary heart disease and stroke. Cox models were fitted to assess the home BP variability-CVD risk association...
January 2018: Hypertension
https://www.readbyqxmd.com/read/28956652/association-between-sleep-disorders-and-morning-blood-pressure-in-hypertensive-patients
#13
Xinran Li, Jiangbo Li, Kai Liu, Shenzhen Gong, Rufeng Shi, Pei Pan, Yujie Yang, Xiaoping Chen
Sleep disorders are known to increase the risk of hypertension, yet few studies have investigated the relation between sleep disorders and morning blood pressure (BP). This study aimed to determine, whether the morning BP is associated with sleep quality and sleep-disordered breathing. A total of 144 hypertensive patients were included in this cross-sectional study. Each subject underwent anthropometric measurements, biochemical testing, 24-h ambulatory BP monitoring, and polysomnography (PSG). Sleep quality and sleep-disordered breathing were determined by PSG parameters of sleep architecture and sleep respiratory...
September 28, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28948098/morning-surge-in-blood-pressure-and-sympathetic-activity-in-mongolians-and-han-chinese-a-multimodality-investigation-of-hypertension-and-dyssomnia
#14
Guanhua Huang, Xiaoming Yang, Jing Huang
BACKGROUND: Hypertension and dyssomnia are increasing significantly in Mongolians, and the related factors of ethnic differences in hypertension and dyssomnia between Mongolians and Han Chinese are unclear. This study examined the relationship of morning surge in blood pressure (MBP) with ethnicity, sleep situation, and sympathetic activity throughout the day. METHODS: Of 692 hypertensive patients screened, 202 subjects with dyssomnia were selected. They were then divided into Mongolian (n = 87) and Han (n = 115) groups...
2017: PeerJ
https://www.readbyqxmd.com/read/28942619/morning-surge-and-nocturnal-dipping-pattern-two-different-entities-or-statistical-gymnastics
#15
Jouni K Johansson, Teemu J Niiranen
No abstract text is available yet for this article.
November 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28854728/a-second-dose-of-kisspeptin-54-improves-oocyte-maturation-in-women-at-high-risk-of-ovarian-hyperstimulation-syndrome-a-phase-2-randomized-controlled-trial
#16
Ali Abbara, Sophie Clarke, Rumana Islam, Julia K Prague, Alexander N Comninos, Shakunthala Narayanaswamy, Deborah Papadopoulou, Rachel Roberts, Chioma Izzi-Engbeaya, Risheka Ratnasabapathy, Alexander Nesbitt, Sunitha Vimalesvaran, Rehan Salim, Stuart A Lavery, Stephen R Bloom, Les Huson, Geoffrey H Trew, Waljit S Dhillo
STUDY QUESTION: Can increasing the duration of LH-exposure with a second dose of kisspeptin-54 improve oocyte maturation in women at high risk of ovarian hyperstimulation syndrome (OHSS)? SUMMARY ANSWER: A second dose of kisspeptin-54 at 10 h following the first improves oocyte yield in women at high risk of OHSS. WHAT IS KNOWN ALREADY: Kisspeptin acts at the hypothalamus to stimulate the release of an endogenous pool of GnRH from the hypothalamus...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28834205/role-of-ambulatory-blood-pressure-monitoring-for-the-management-of-hypertension-in-asian-populations
#17
REVIEW
Satoshi Hoshide, Hao-Min Cheng, Qifang Huang, Sungha Park, Chang-Gyu Park, Chen-Huan Chen, Ji-Gwang Wang, Kazuomi Kario
Out-of-clinic blood pressure (BP) measurement, eg, ambulatory BP monitoring, has a strong association with target organ damage and is a powerful predictor of cardiovascular events compared with clinic BP measurement. Ambulatory BP monitoring can detect masked hypertension or various BP parameters in addition to average 24-hour BP level. Short-term BP variability assessed by standard deviation or average real variability, diminished nocturnal BP fall, nocturnal hypertension, and morning BP surge assessed by ambulatory BP monitoring have all been associated with target organ damage and cardiovascular prognosis...
December 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28834120/the-relationship-between-a-blunted-morning-surge-and-a-reversed-nocturnal-blood-pressure-dipping-or-riser-pattern
#18
Takeshi Fujiwara, Naoko Tomitani, Keiko Sato, Ayako Okura, Noriyuki Suzuki, Kazuomi Kario
The authors sought to determine the association between the blunted morning blood pressure (BP) surge and nocturnal BP dipping of the "riser" pattern in 501 patients with hypertension enrolled in the ACHIEVE-ONE (Ambulatory Blood Pressure Control and Home Blood Pressure [Morning and Evening] Lowering by the N-Channel Blocker Cilnidipine) trial. The patients' sleep-trough morning BP surge and prewaking surge were calculated and then classified according to their nocturnal systolic BP reduction pattern as extreme dippers, dippers, nondippers, and risers...
November 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28734791/association-between-nocturnal-blood-pressure-variation-and-wake-up-ischemic-stroke
#19
Hyuk Sung Kwon, Ji Young Kim, Hojin Choi, Seok Joon Lee, Seong-Ho Koh, Young Joo Lee, Hyun Young Kim, Hee-Tae Kim, Juhan Kim, Young Seo Kim
Ischemic stroke during nocturnal sleep, known as wake-up stroke (WUS), has been reported to have more severe symptoms and worse outcomes than non-WUS. However, studies on risk factors for WUS are scarce and the association between nocturnal blood pressure (BP) and WUS is unclear. In this study, we used ambulatory blood pressure monitoring (ABPM) to examine the association between WUS and variation in nocturnal BP. A total of 369 patients with ischemic stroke within one week were consecutively enrolled. ABPM was applied 1-2weeks after the ictus because of possible reactive increments of BP; antihypertensive medications were delayed until ABPM...
October 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28692393/risk-of-fall-related-injury-due-to-adverse-weather-events-philadelphia-pennsylvania-2006-2011
#20
Kathryn Gevitz, Robbie Madera, Claire Newbern, José Lojo, Caroline C Johnson
OBJECTIVES: Following a surge in fall-related visits to local hospital emergency departments (EDs) after a severe ice storm, the Philadelphia Department of Public Health examined the association between inclement winter weather events and fall-related ED visits during a 5-year period. METHODS: Using a standardized set of keywords, we identified fall-related injuries in ED chief complaint logs submitted as part of Philadelphia Department of Public Health's syndromic surveillance from December 2006 through March 2011...
July 2017: Public Health Reports
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