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fourth ventricular tumour

T Hakan, F V Aker
Rosette-forming glioneuronal tumour (RGNT) of the fourth ventricle is one of the newly described primary tumours of the central nervous system. These tumours have two components of both neurocytic and glial areas but usually the glial component of the tumour predominates. They have biphasic cytoarchitecture with two elements; neurocytic rosettes resembling Homer-Wright rosettes, and astrocytic component resembling a pilocytic astrocytoma. They are low-grade tumours with lack of histopathological signs of malignancy...
2016: Folia Neuropathologica
Sven Bercker, Jürgen Meixensberger, Sven Laudi, Christof Renner
A 33-years-old male patient presented with cardiac arrhythmias, acute shock and multiple organ dysfunction after the surgical removal of a massive epidermoid posterior to the brainstem. The patient initially presented with paraesthesia along the right C6 dermatome due to a big tumour at the brain stem. Surgical removal was performed without adverse events and he was transferred to our intensive care unit (ICU) immediately after the operation. Though initially showing a stable postsurgical course he developed cardiac arrhythmias and a state of acute distributive shock with consecutive multi organ failure...
2016: BMJ Case Reports
Kara O'Donnell, Alpha Tsui, Kate Drummond, Frank Gaillard
Ependymomas are glial series tumours that can occur throughout the neural axis, usually in close proximity to the ventricles or central canal. While the fourth ventricle is a common location for ependymoma, we present a rare case of an entirely intraparenchymal infratentorial tumour, remote from the ventricular surface, and discuss the imaging characteristics that may suggest the diagnosis. The histological features, which remain identical despite the varied morphology of intraventricular versus intraparenchymal tumours, are also considered...
February 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
John E Lawrence, Ramesh Nadarajah, Taryn D Treger, Mark Agius
Colloid cysts account for approximately 2% of primary brain tumours and the majority of cases are identified in the fourth and fifth decade. They are small, gelatinous neoplasms lined by a single layer of mucin-secreting columnar epithelium that are thought to arise from errors in folding of the primitive neuroepithelium. They develop in the rostral aspect of the third ventricle in the foramen of Monro in 99% of cases and despite their benign histology carry a poor prognosis, with a mortality greater than 10% in symptomatic cases...
September 2015: Psychiatria Danubina
Mustafa Akın, Sefika Arzu Ergen, Büge Oz, Gülyüz Atkovar, Ismet Sahinler
BACKGROUND: Ganglioneuroblastomas (GNBs) are rare embryonic neoplasms in the spectrum of neuroblastic tumours and 80% of cases occur in the first decade. In adults, GNBs are usually located in the retroperitoneum, mediastinum and neck but intracranial GNBs are extremely rare. CASE REPORT: A 34-year-old male applied to the Department of Neurology outpatient clinic with a two month history of headache and numbness in his legs. Detailed examinations and cranial CT were performed and showed a mass with a 5 cm diameter running from the third to the fourth ventricle...
June 2014: Balkan Medical Journal
Julián Castro-Castro, D Castro-Bouzas, Pedro Luis Prieto-Casal, Ivana Dolores Carcacia-Hermilla, Montserrat Riu-Lloveras, José Enrique Castro-Gómez
INTRODUCTION. Intracranial subependymomas are rare, slow-growing, noninvasive, benign tumors. They are most often located in the fourth ventricle. Most of these tumors are discovered incidentally during autopsy. Routine medical checkups using neuroimaging techniques have increased their diagnosis. Subependymomas may present with symptoms related to cerebrospinal fluid obstruction or mass effect. CASE REPORT. A 52-year-old man presented with severe headache and mental deterioration with memory disturbances and bradypsychia...
March 16, 2013: Revista de Neurologia
(no author information available yet)
Adjuvant cytotoxic chemotherapy following surgical treatment of nonmetastatic breast cancer usually includes an anthracycline. The addition of trastuzumab should be considered for women whose tumours overexpress HER-2 protein. Trastuzumab has been approved in the European Union since 2006 for adjuvant treatment of breast cancer. In 2011, the indications were further specified to allow the use of adjuvant trastuzumab in both anthracycline-based and non-anthracycline protocols. In 2006, the results of the first 3 trials of adjuvant chemotherapy showed an absolute gain in overall survival of about 4% after 4 years with trastuzumab...
December 2012: Prescrire International
D Reddy, T Gunnarsson, K Scheinemann, J P Provias, S K Singh
BACKGROUND: Choroid plexus papillomas of the third ventricle in newborn infants are quite rare and present a significant surgical challenge. This case report illustrates the utility of endoscopy in facilitating tumor resection. PATIENT: A 6-week-old boy, born prematurely at a gestational age of 35 weeks, presented with hydrocephalus secondary to a choroid plexus papilloma in the third ventricle, extending to the aqueduct of Sylvius and into the fourth ventricle...
October 2011: Minimally Invasive Neurosurgery: MIN
B-Y Zhang, B Yin, Y-X Li, J-S Wu, H Chen, X-Q Wang, Dao-Ying Geng
AIM: To present the neuroradiological and clinical findings of fourth-ventricular meningiomas to increase awareness of this entity. MATERIALS AND METHODS: The computed tomography (CT; n=5), magnetic resonance imaging (MRI; n=9) features and clinical presentations of 10 patients with pathologically documented fourth-ventricular meningiomas were retrospectively analysed. RESULTS: All tumours appeared as well-demarcated masses in the fourth ventricle at CT and MRI...
May 2012: Clinical Radiology
Elżbieta Szwench, Mariola P Czkowska, Krzysztof Marczewski, Anna Klisiewicz, Ilona Micha Owska, Iwona Ciuba, Magdalena Januszewicz, Aleksander Prejbisz, Piotr Hoffman, Andrzej Januszewicz
BACKGROUND. Phaeochromocytomas and paragangliomas are rare, mostly benign catecholamine-producing tumours of chromaffin cells of the adrenal medulla or of extra-adrenal paraganglia. Phaeochromocytoma may occur at any age, the greatest frequency being in the fourth and fifth decades. Only on extremely rare occasions does the tumour develop in the very old patients. METHODS. We are describing an 86-year-old patient with phaeochromocytoma, presenting with reversible myocardial dysfunction. RESULTS. This very old patient with phaeochromocytoma had hypertension characterized by labile blood pressure values and increased daytime blood pressure variability...
December 2011: Blood Pressure
O T Burgan, A Bahl, V Critcher, H S Zaki, P J McMullan, S Sinha
Clear cell meningiomas are rare meningioma variants and are recognized as World Health Organization grade II tumours. They may be difficult to manage given their propensity to recur early especially if present in surgically challenging locations. We describe a rare case of a fourth ventricular clear cell meningioma without dural attachment in a 14-year-old boy with an unusual presentation of failure to thrive. The case is presented in detail and a review of the recent literature is discussed.
2010: Pediatric Neurosurgery
Christopher Palmer, Pratipal Kalsi, David Scoones, Nicholas Bradey, Roger Strachan
Choroid plexus papillomas are rare tumours, which occasionally spread both intracranially and down the spinal canal. Spinal metastasis has been reported infrequently and only once many years since the initial diagnosis. This is the first reported case of late recurrence, metastasis and transformation of a benign to an atypical lesion.
August 2010: British Journal of Neurosurgery
Kimberley A Myers, Kenny K Wong, Marion Tipple, Shubhayan Sanatani
Four cases of pediatric cardiac tumours (PCTs) associated with ventricular arrhythmias are reported. Sudden cardiac death attributable to the tumour occurred in two children. A third child received an implantable cardioverter defibrillator and the fourth had persistent ventricular arrhythmia despite medical therapy. Most PCTs are considered benign; however, the development of malignant arrhythmias may complicate the management of these tumours in some patients. The literature regarding the arrhythmogenic potential of PCTs and the use of implantable cardioverter defibrillators in these patients is reviewed...
February 2010: Canadian Journal of Cardiology
Neilank K Jha, Shanil Ebrahim, Aria Fallah, Aleksa Cenic, Rocco A De Villiers
We report a case of a 22-year-old man presenting with a fourth ventricular tumour and associated chronic obstructive hydrocephalus likely leading to thinning of the cranium. Intraoperatively, he developed an epidural hematoma secondary to a fracture of the temporal bone by application of the three-point skull fixator. This is the second reported adult case of an iatrogenic epidural hematoma secondary to pin-site complications. We advocate the careful placement of the pins and suggest the tightening force be catered individually especially in pediatric patients or patients with chronic hydrocephalus...
April 2009: British Journal of Neurosurgery
C S Hill, A F Khan, S Bloom, S McCartney, D Choi
We document the case of a 69-year-old man presenting with 6 weeks of intractable vomiting. Magnetic Resonance Imaging showed a homogenously enhancing mass in the caudal fourth ventricle. Surgical exploration and biopsy was performed and pathological examination demonstrated a high-grade B-cell lymphoma. The lesion was a primary tumour in an immuno-competent patient. Despite the increasing incidence of primary central nervous system lymphomas this is believed to be only the third ever case to have occurred at this rare site...
June 2009: Journal of Neuro-oncology
Kaushik Roy, Asis Kumar Bhattacharyya, P Tripathy, M K Bhattacharyya, Bibhukalyani Das
Twenty-eight cases of intracranial epidermoids were operated over a period of 10 years at the Bangur Institute of Neurology, Kolkata; 17 of them were male and 11 were female with an age range of 11 to 55 (mean 28.21) years. Their locations include--cerebellopontine angle region (n = 15), fourth ventricle (n = 6), lateral ventricle (n = 3), corpus callosum (n = 2), pineal region (n = 1) and basal cistern near temporal lobe (n = l). Hearing loss and vertigo were commonest features of cerebellopontine angle epidermoids...
July 2008: Journal of the Indian Medical Association
Grazyna M Szpak, Eliza Lewandowska, Bogna Schmidt-Sidor, Elzbieta Pasennik, Joanna Modzelewska, Tomasz Stepień, Grzegorz Zdaniuk, Jerzy Kulczycki, Teresa Wierzba-Bobrowicz
This report presents a case of widespread intramedullary giant cell ependymoma arising from the central canal of the C4 segment of the spinal cord in a 28-year-old man admitted to hospital with tetraplegia and signs of increased intracranial pressure, eight months after surgical spinal cervical decompression without tetraplegia improvement. Magnetic resonance imaging and autopsy revealed a tumour extending from segment C3/C4 of the spinal cord to the lower half of the fourth ventricle with coexisting syringomyelia...
2008: Folia Neuropathologica
Gianpiero Tamburrini, Luca Massimi, Massimo Caldarelli, Concezio Di Rocco
BACKGROUND: The effectiveness of antibiotic pre-treated ventricular catheters in reducing the risk of CSF infections (determined on CSF cultures) resulting from the use of per-operative external ventricular drainages (EVD) and the success rate of post-operative endoscopic third ventriculostomy (ETV) in the management of persistent hydrocephalus after posterior cranial fossa tumour removal are assessed. METHOD: Forty-seven children (group I) were prospectively managed by means of per-operative antibiotic impregnated EVD, post-operative ICP monitoring, and ETV...
October 2008: Acta Neurochirurgica
K Hongo, H Nakagawa, K Tamai, S Kobayashi
Postoperative paraplegia following non-spinal surgical procedures is very rare. We report a rare case of medulloblastoma in which paraplegia occurred after surgery. A 4-year-old boy suffered frequent vomiting and was found to have a tumour in the fourth ventricle associated with obstructive hydrocephalus. The tumour had already disseminated in the upper cervical spinal cord and thoracic cord. After surgical removal of the fourth ventricular tumour in the prone position, the patient developed paraplegia of the lower extremities...
November 1999: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Mi Iddrissu, Tk Dakurah, Gk Wepeba
SummaryEpendymomas are relatively uncommon and present with a spectrum of biological and clinical characteristics that make specific recommendations regarding their treatment difficult and assignment of prognostic factors controversial. The case of fourth ventricular anaplastic epednymoma in a four-year-old child is reported in which the initial presentation was deterioration of the level of consciousness secondary to acute obstructive hydrocephalus. An initial insertion of a ventriculo-peritoneal shunt (V-P) to deal with the acute intracranial hypertension was done...
March 2005: Ghana Medical Journal
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