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Use of calcium excretion

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https://www.readbyqxmd.com/read/28501403/use-of-calcitriol-to-maintain-postpartum-blood-calcium-and-improve-immune-function-in-dairy-cows
#1
A Vieira-Neto, I R P Lima, F Lopes, C Lopera, R Zimpel, L D P Sinedino, K C Jeong, K Galvão, W W Thatcher, C D Nelson, J E P Santos
Our objectives were to determine the effects of an injectable formulation of calcitriol on mineral metabolism and immune function in postpartum Holstein cows that received an acidogenic diet prepartum to minimize hypocalcemia. In experiment 1, cows within 6 h of calving received calcitriol (0, 200, or 300 μg) to determine the dose needed to increase plasma concentrations of Ca; 300 μg was sufficient to sustain Ca for at least 3 d. In experiment 2, multiparous cows were assigned randomly to receive only vehicle (control, n = 25) or 300 μg of calcitriol (n = 25) subcutaneously within the first 6 h after calving...
May 10, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28464092/reducing-mineral-usage-in-feedlot-diets-for-nellore-cattle-ii-impacts-of-calcium-phosphorus-copper-manganese-and-zinc-contents-on-intake-performance-and-liver-and-bone-status
#2
L F Prados, D F T Sathler, B C Silva, D Zanetti, S C Valadares Filho, H M Alhadas, E Detmann, S A Santos, L D S Mariz, M L Chizzotti
Weaned Nellore bulls ( = 36; 274 ± 34 kg) were used in a randomized block design with a 2 × 2 factorial arrangement of treatments to evaluate intake, fecal excretion, and performance with different concentrations of minerals. Experimental diets were formulated with 2 concentrations of Ca and P (macromineral factor; diet supplying 100% of Ca and P according to BR-CORTE () [CaP+] or diet without limestone and dicalcium phosphate [CaP-]) and 2 concentrations of microminerals (micromineral factor; diet with supplementation of microminerals [Zn, Mn, and Cu; CuMnZn+] or diet without supplementation of microminerals [Zn, Mn, and Cu; CuMnZn-])...
April 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28464082/reducing-mineral-usage-in-feedlot-diets-for-nellore-cattle-i-impacts-of-calcium-phosphorus-copper-manganese-and-zinc-contents-on-microbial-efficiency-and-ruminal-intestinal-and-total-digestibility-of-dietary-constituents
#3
D F T Sathler, L F Prados, D Zanetti, B C Silva, S C Valadares Filho, M V C Pacheco, P M Amaral, L N Rennó, M F Paulino
This study evaluated intake, microbial efficiency, and ruminal, small and large intestinal, and total digestibility of DM, OM, CP, and NDF, as well as availability of Ca, P, Mg, Na, K, Cu, Mn, and Zn in Zebu cattle fed with or without supplemental sources of Ca and P or a micromineral premix. Five rumen- and ileum-cannulated Nellore bulls (BW = 200 ± 10.5 kg; 9 mo) were used in the experiment, distributed in a 5 × 5 Latin square design. The experiment was developed in a 2 × 2 + 1 factorial design to measure the effects of mineral supplementation on intake, digestibility, and site of nutrient absorption...
April 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28442523/a-detailed-comparison-of-morning-and-random-urine-specimen-levels-with-24-hour-urinary-excretion-levels-of-seven-biochemical-parameters-with-a-proposed-formula
#4
Ziba Shojaei-Far, Farideh Razi, Fatemeh Bandarian, Camelia Rambod, Mostafa Qorbani
This study aimed to evaluate the validity of the suggested method (SM) to estimate the urinary level of seven biochemical parameters within 24 hours with an innovative formula using morning and random urine specimens. A total of 133 clients referring to the laboratory of the Endocrinology & Metabolism Research Institute, Tehran University of Medical Sciences, participated voluntarily in the investigation with providing three urine samples of 24-hour, morning and random. Seven biochemical parameters (calcium, phosphorus, urea, creatinine, uric acid, microalbumin and protein) were measured in all three samples...
March 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/28441892/changes-in-blood-and-urinary-cadmium-levels-and-bone-mineral-density-according-to-osteoporosis-medication-in-individuals-with-an-increased-cadmium-body-burden
#5
S-Y Eom, D-H Yim, S-M Hong, Y-D Kim, H Kim, B-S Choi, J-D Park, C-H Park, G-B Kim, S-D Yu
The aim of this study was to assess changes in bone mineral density (BMD) and cadmium (Cd) levels in blood and urine in individuals living in a Cd-contaminated area according to the type of osteoporosis medication over a three-year period. This follow-up study included 204 residents living in the vicinity of a closed copper refinery, who had been found to have elevated urinary or blood Cd levels. Cd levels in the blood and urine, as well as BMD, were measured every 6 months. After the first BMD measurement, individuals were prescribed antiresorptives such as alendronate or vitamin D and calcium, according to their BMD...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28422036/physicochemical-factors-of-the-urine-of-children-with-hypercalciuria
#6
Mercedes Ubetagoyena-Arrieta, Jorge Martínez Sáenz de Jubera, María Nieves Corera-Casty, Eduardo González Pérez-Yarza, Irati García-Albizua
OBJECTIVE: Hypercalciuria is a common lithogenic risk factor. The aim of this study was, first, to study the characteristics of urine biochemical factors of children with hypercalciuria (HC) and compare them with those of children without hypercalciuria. Second, to analyze the differences between children with HC and lithiasis (HCL) and children with HC and no lithiasis (HCNL). METHODS: The sample was composed by 111 cases with HC, divided into 2 groups: HCNL group, consisting of 93 cases with no personal history of kidney stones, and HCL group, 18 cases with personal history of kidney stones...
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28410612/milk-protein-based-formulas-containing-different-oils-affect-fatty-acids-balance-in-term-infants-a-randomized-blinded-crossover-clinical-trial
#7
Carolina Oliveira de Souza, Maria Efigênia Q Leite, John Lasekan, Geraldine Baggs, Lorena Silva Pinho, Janice Izabel Druzian, Tereza Cristina M Ribeiro, Ângela P Mattos, José A Menezes-Filho, Hugo Costa-Ribeiro
BACKGROUND: Palm olein is used in infant formula fat blends in order to match the fatty acid profile of human milk. While the effects on fatty acid balance have been evaluated, the use of palm olein in combination with palm kernel oil and supplementation with docosahexaenoic acid (DHA) and arachidonic acid (ARA) has not been similarly assessed in infants. This study evaluated the effects of infant formulas containing different fat compositions on the balance of fat, fatty acids, and calcium...
April 14, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28384348/de-novo-transcriptome-analysis-of-the-excretory-tubules-of-carausius-morosus-phasmatodea-and-possible-functions-of-the-midgut-appendices
#8
Matan Shelomi
The Malpighian tubules are the insect excretory organs, responsible for ion and water homeostasis and elimination of nitrogenous wastes. Post-genomic assays suggest they also metabolize and detoxify xenobiotic compounds and have antimicrobial properties. The Phasmatodea have an additional, unique set of excretory organs referred to predominantly as midgut appendices. Their function and how it compares to phasmid and other insect Malpighian tubules is unknown. Hypotheses include carbonic anhydrase activity, calcium and metal cation sequestration, and xenobiotic transport...
2017: PloS One
https://www.readbyqxmd.com/read/28383779/factors-influencing-pre-operative-urinary-calcium-excretion-in-primary-hyperparathyroidism
#9
Reto M Kaderli, Philipp Riss, Angelika Geroldinger, Andreas Selberherr, Christian Scheuba, Bruno Niederle
OBJECTIVE: Normal or elevated 24-hour urinary calcium (Ca) excretion is a diagnostic marker in primary hyperparathyroidism (PHPT). It is used to distinguish familial hypocalciuric hypercalcaemia (FHH) from PHPT by calculating the Ca/creatinine clearance ratio (CCCR). The variance of CCCR in patients with PHPT is considerable. The aim of this study was to analyse the parameters affecting CCCR in patients with PHPT. DESIGN: The data were collected prospectively. Patients with sporadic PHPT undergoing successful surgery were included in a retrospective analysis...
April 6, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28369876/a-systematic-review-and-meta-analysis-of-hypocalciuria-in-pre-eclampsia
#10
REVIEW
Kristen M McMaster, Andrew M Kaunitz, Prardhana Burbano de Lara, Luis Sanchez-Ramos
BACKGROUND: Small observational studies have demonstrated that pre-eclampsia is associated with hypocalciuria. OBJECTIVES: To compare urinary calcium excretion in pre-eclampsia, gestational hypertension, and chronic hypertension with that in normotensive pregnancies. SEARCH STRATEGY: Online databases were searched through February 2016 using medical subject headings "calcium homeostasis," "calcium excretion," "hypocalciuria," and "pre-eclampsia...
March 31, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28357180/diagnosis-and-treatment-of-dent-disease-in-10-chinese-boys
#11
Guohua He, Hongwen Zhang, Fang Wang, Xiaoyu Liu, Huijie Xiao, Yong Yao
Dent disease is a rare X-linked recessive proximal tubular disorder that affects mostly male patients in childhood or early adult life. Dent disease is clinically characterized by the presence of low molecular weight proteinuria (LMWP), hypercalciuria, medullary nephrocalcinosis, nephrolithiasis, and progressive renal failure. The clinical features, diagnosis, and treatment of Dent disease were examined in 10 Chinese boys. All 10 childhood cases of Dent disease in China presented with tubular proteinuria in the nephrotic range and hypercalciuria...
February 2017: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/28351028/influence-of-feeding-types-during-the-first-months-of-life-on-calciuria-levels-in-healthy-infants-a-secondary-analysis-from-a-randomized-clinical-trial
#12
Natalia Ferré, Carmen Rubio-Torrents, Veronica Luque, Ricardo Closa-Monasterolo, Veit Grote, Berthold Koletzko, Piotr Socha, Dariusz Gruszfeld, Jean Paul Langhendries, Anne Sengier, Elvira Verduci, Joaquin Escribano
BACKGROUND/AIMS: Dietary factors can modify calciuria. We aim to investigate urinary calcium excretion in healthy infants according to their protein. METHODS: Secondary data analysis from a randomized clinical trial where healthy term infants were randomized after birth to a higher (HP) or lower (LP) protein content formula that was consumed until age 1 year. A non-randomized group of breastfed (BF) infants was used for reference. Anthropometry, dietary intakes and calciuria (calcium/creatinine ratios) from spot urine samples were assessed at ages 3 and 6 months...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28340119/the-risk-of-nephrolithiasis-is-causally-related-to-inactive-matrix-gla-protein-a-marker-of-vitamin-k-status-a-mendelian-randomization-study-in-a-flemish-population
#13
Fang-Fei Wei, Lutgarde Thijs, Zhen-Yu Zhang, Lotte Jacobs, Wen-Yi Yang, Erika Salvi, Lorena Citterio, Nicholas Cauwenberghs, Tatiana Kuznetsova, Nadja E A Drummen, Azusa Hara, Paolo Manunta, Yan Li, Peter Verhamme, Karel Allegaert, Daniele Cusi, Cees Vermeer, Jan A Staessen
Background.: Vitamin K (VK)-dependent γ-glutamate carboxylation and serine phosphorylation activate matrix Gla protein (MGP) to a potent locally acting inhibitor of calcification. Nephrolithiasis represents a process of unwanted calcification associated with substantial mortality and high recurrence rates. We hypothesized that the risk of nephrolithiasis increases with VK shortage, as exemplified by higher plasma levels of desphospho-uncarboxylated MGP (dp-ucMGP). Methods...
March 15, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28331214/antihypertensive-medications-and-the-risk-of-kidney-stones-in-older-adults-a-retrospective-cohort-study
#14
R Todd Alexander, Eric McArthur, Racquel Jandoc, Blayne Welk, Jade S Hayward, Arsh K Jain, Branko Braam, Veit Flockerzi, Amit X Garg, Robert Ross Quinn
Antihypertensives are widely prescribed and could influence kidney stone risk by altering urinary calcium excretion. However, the impact of different classes of antihypertensives on kidney stone risk is unknown. To assess this impact, we conducted a retrospective, population-based cohort study using linked health administrative databases. Individuals aged >65 years who initiated one of the four antihypertensive classes (that is, angiotensin-converting enzyme inhibitors (ACEis)/angiotensin receptor blockers (ARBs), beta-blockers, calcium channel blockers or thiazide diuretics) were included...
March 23, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28322159/towards-predicting-the-cytochrome-p450-modulation-from-qsar-to-proteochemometric-modeling
#15
Watshara Shoombuatong, Philip Prathipati, Veda Prachayasittikul, Nalini Schaduangrat, Aijaz Ahmad Malik, Reny Pratiwi, Sompon Wanwimolruk, Jarl E S Wikberg, Matthew Paul Gleeson, Ola Spjuth, Chanin Nantasenamat
Drug metabolism determines the fate of a drug when it enters the human body and is a critical factor in defining their absorption, distribution, metabolism, excretion and toxicity (ADMET) characteristics. Among the various drug metabolizing enzymes, cytochrome P450s (CYP450) constitute an important protein family that aside from functioning in xenobiotic metabolism is also responsible for a diverse array of other roles encompassing steroid and cholesterol biosynthesis, fatty acid metabolism, calcium homeostasis, neuroendocrine functions and growth regulation...
March 20, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28321001/comparative-effects-of-an-angiotensin-ii-receptor-blocker-arb-diuretic-vs-arb-calcium-channel-blocker-combination-on-uncontrolled-nocturnal-hypertension-evaluated-by-information-and-communication-technology-based-nocturnal-home-blood-pressure-monitoring%C3%A3-the
#16
Kazuomi Kario, Naoko Tomitani, Hiroshi Kanegae, Hajime Ishii, Kazuaki Uchiyama, Kayo Yamagiwa, Toshihiko Shiraiwa, Tomohiro Katsuya, Tetsuro Yoshida, Kiyomi Kanda, Shinji Hasegawa, Satoshi Hoshide
BACKGROUND: Nocturnal blood pressure (BP) is an independent risk factor of cardiovascular events. The NOCTURNE study, a multicenter, randomized controlled trial (RCT) using our recently developed information and communication technology (ICT) nocturnal home BP monitoring (HBPM) device, was performed to compare the nocturnal HBP-lowering effects of differential ARB-based combination therapies in 411 Japanese patients with nocturnal hypertension (HT).Methods and Results:Patients with nocturnal BP ≥120/70 mmHg at baseline even under ARB therapy (100 mg irbesartan daily) were enrolled...
March 17, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28302355/effects-of-short-term-calcium-supplementation-in-children-and-adolescents-with-phenylketonuria
#17
Nancy Y Y Tanaka, Marlene F Turcato, Carolina F Nicoletti, Carla B Nonino, Luciana D Martins, Odilon Iannetta, Carlos Tostes Guerreiro, Gisele G Santos, Júlio S Marchini
Reduction of bone mineral density and the risk of osteopenia have been reported to occur in phenylketonuria (PKU) patients. This study aimed to evaluate the short-term effects of calcium supplementation in phenylketonuric children and adolescents. The study included 18 patients with PKU aged 5-18 yr (61% male) under clinical and nutritional treatment. Evaluation of food intake, anthropometry, and biochemical and phalangeal quantitative ultrasound were performed before (phase 1) and after (phase 2) calcium supplementation (1000 mg/d) for 34 d...
March 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28287014/preparation-and-optimization-of-tablets-containing-a-self-nano-emulsifying-drug-delivery-system-loaded-with-rosuvastatin
#18
Heba F Salem, Rasha M Kharshoum, Abdel Khalek A Halawa, Demiana M Naguib
BACKGROUND: Rosuvastatin (ROS) calcium is the latest synthetic drug in the statin group that has an anti-hyperlipidemic activity. It is available as tablets, and its poor aqueous solubility, slow dissolution rate and low-absorption extent result in less than 20% bioavailability and about 80% being excreted unchanged in the feces without absorption. OBJECTIVE: To utilize nanotechnology to reformulate ROS as a self-nano-emulsifying drug delivery system (SNEDDS), and utilizing design optimization to fabricate the SNEDDS as a tablet...
March 13, 2017: Journal of Liposome Research
https://www.readbyqxmd.com/read/28262194/protective-effect-of-propolis-in-proteinuria-crystaluria-nephrotoxicity-and-hepatotoxicity-induced-by-ethylene-glycol-ingestion
#19
Nawal El Menyiy, Noori Al Waili, Meryem Bakour, Hamza Al-Waili, Badiaa Lyoussi
BACKGROUND AND AIMS: Propolis is a natural honeybee product with wide biological activities and potential therapeutic properties. The aim of the study is to evaluate the protective effect of propolis extract on nephrotoxicity and hepatotoxicity induced by ethylene glycol in rats. METHODS: Five groups of rats were used. Group 1 received drinking water, group 2 received 0.75% ethylene-glycol in drinking water, group 3 received 0.75% ethylene-glycol in drinking water along with cystone 500 mg/kg/body weight (bw) daily, group 4 received 0...
October 2016: Archives of Medical Research
https://www.readbyqxmd.com/read/28218647/diabetes-mellitus-and-younger-age-are-risk-factors-for-hyperphosphatemia-in-peritoneal-dialysis-patients
#20
Rameez Imtiaz, Steven Hawken, Brendan B McCormick, Simon Leung, Swapnil Hiremath, Deborah L Zimmerman
Hyperphosphatemia has been associated with adverse outcomes in patients with end stage kidney disease (ESKD). The purpose of this study was to determine risk factors for hyperphosphatemia in ESKD patients treated with peritoneal dialysis (PD). This information will be used to develop a patient specific phosphate binder application to facilitate patient self-management of serum phosphate. Adult PD patients documented their food, beverage, and phosphate binder intake for three days using a dietitian developed food journal...
February 17, 2017: Nutrients
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