Jason Hill, Cailing Liu, Phillip Deardorff, Behrouz Tavakol, William Eddington, Vance Thompson, Dan Gore, Michael Raizman, Desmond C Adler
<u>Purpose</u> : Corneal collagen crosslinking (CXL) through an intact epithelium (epi-on) at high irradiance could potentially improve patient comfort, visual recovery, and clinical workflow compared to conventional epi-off CXL. However, intact epithelium limits stromal delivery of the oxygen, photosensitizer, and ultraviolet-A (UV-A) radiation needed to drive CXL. This ex vivo study evaluated three different epi-on CXL protocols compared to positive and negative controls, specifically focusing on the impact of supplemental oxygen...
September 18, 2019: Current Eye Research