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https://www.readbyqxmd.com/read/27574383/safety-and-effectiveness-of-closure-devices-applied-to-a-stented-common-femoral-artery-a-retrospective-analysis
#1
Nicolas W Shammas, Gail A Shammas, Thomas Harris, Cara M Voelliger, Andrew N Shammas, Michael Jerin
Bailout stenting of the common femoral artery (CFA) may become necessary with failed balloon angioplasty or atherectomy or in case of bleeding requiring a covered stent over the arteriotomy site. Reaccessing the CFA through a previously placed stent may occur during angiography. The safety and effectiveness of applying a closure device, or manual compression to achieve hemostasis through an accessed stented CFA are unknown. All patients in our practice that underwent CFA stenting were identified using billing records for 3 years (January 1, 2010-February 28, 2013)...
September 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/26945253/success-safety-and-efficacy-of-the-mynx-femoral-closure-device-in-a-real-world-cohort-single-center-experience
#2
David Hutchings, Afzal Hayat, Arun Karunakaran, Nadim Malik
BACKGROUND: Femoral artery closure device use following percutaneous cannulation allows earlier mobilization, reduced staff burden, and improved comfort for patients compared with manual compression. The Mynx device (Access Closure, Inc), a novel extravascular closure device, uses a water-soluble non-thrombogenic polyethylene glycol plug. METHODS: We report retrospective analysis of success, complication rates, and associated factors in 432 consecutive patients undergoing elective outpatient coronary angiography in a single United Kingdom center...
March 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/26728544/active-versus-passive-anchoring-vascular-closure-devices-following-percutaneous-coronary-intervention-a-safety-and-efficacy-comparative-analysis
#3
COMPARATIVE STUDY
Nevin C Baker, Ricardo O Escarcega, Michael J Lipinski, Marco A Magalhaes, Edward Koifman, Sarkis Kiramijyan, Smita I Negi, Rebecca Torguson, Ron Waksman
OBJECTIVE: We evaluate the prevalence of complications and failure rates between the most commonly used "active" anchoring vascular closure device (VCD), AngioSeal™ and the "passive" anchoring VCD, Mynx™, in all-comers undergoing percutaneous coronary intervention (PCI). METHODS: A total of 4,074 patients between 2008 and 2014, representing an era when both devices were available, were included. Thirty-two percent were acute coronary syndromes (37% STEMI). VCD choice was at the operator's discretion and included AngioSeal (n = 2,910) or Mynx (1,164)...
February 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/25661765/mynx-vascular-closure-device-achieves-reliable-closure-and-hemostasis-of-percutaneous-transfemoral-venous-access-in-a-porcine-vascular-model
#4
S Sanjay Srivatsa, Arjun Srivatsa, Taylor A Spangler
AIMS: Vascular closure device (VCD)-based venous closure has been anecdotally reported, but systematic evaluation of the reparative response of the vessel wall to venous closure is lacking. The need to control groin complications, and minimize risks associated with postponed sheath removal under conditions of persistent anticoagulation, has generated interest in the role of VCDs for venous access closure. We sought to characterize the vessel wall response to venous closure, both acutely and in delayed fashion at 30 days using angiography, ultrasound, and histology...
February 2015: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/23913615/successful-aspiration-of-mynx-vascular-closure-device-sealant-that-embolized-to-the-popliteal-artery
#5
Siddhartha Rao, Prashant Kaul, George A Stouffer
The Mynx (AccessClosure, Inc) is a vascular closure device that uses extravascular deployment of a self-expanding polyethylene glycol (PEG) sealant delivered during removal of the procedural sheath. An intravascular balloon is inflated at the arteriotomy site to prevent leakage of the sealant into the bloodstream. The complication rate with the Mynx vascular closure device is low, but there have been reports of distal embolization of the sealant. Optimal treatment of this complication is unknown, with limited published data relating only to surgical extraction...
August 2013: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/23868215/safety-and-efficacy-of-percutaneous-femoral-artery-access-followed-by-mynx-closure-in-cerebral-neurovascular-procedures-a-single-center-analysis
#6
Ramesh Grandhi, Hilal Kanaan, Aalap Shah, Gillian Harrison, Christopher Bonfield, Tudor Jovin, Brian Jankowitz, Michael Horowitz
BACKGROUND AND PURPOSE: Percutaneous transfemoral arterial procedures rely on a variety of vascular closure methods. We studied closure success and complications after using the Mynx vascular closure device in cerebral neurovascular procedures. METHODS: We prospectively analyzed patients undergoing diagnostic cerebral angiogram or neurointervention with arteriotomy closure using the Mynx device. Patient demographics and procedural factors were recorded. Statistical analyses compared groups and identified predictors of device failure and complication...
July 2014: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/23155673/distal-embolization-from-mynx-device
#7
Ankur Gupta, Immad Sadiq, Steven Borer
Vascular closure devices are commonly used to obtain arterial access site closure after cardiovascular procedures. They are popular as they decrease time to hemostasis and ambulation while improving patient comfort by eliminating need for compression. However, complications due to vascular closure devices are not uncommon. We report a case of possible intravascular distal embolization of water-soluble PEG polymer that is deployed extravascular using the Mynx vascular closure device.
October 2012: Connecticut Medicine
https://www.readbyqxmd.com/read/22266794/occurrence-of-angiographic-femoral-artery-complications-after-vascular-closure-with-mynx-and-angioseal
#8
Kyle M Fargen, Gregory J Velat, Matthew F Lawson, Charles A Ritchie, Christopher Firment, Brian L Hoh, Jeffery A Bennett, J Mocco
INTRODUCTION: There have been recent reports of high vascular complication rates after the use of the Mynx vascular closure device (VCD). At our institution, vascular complications due to these devices have rarely been encountered. A study was undertaken to retrospectively compare angiographic abnormalities seen after femoral artery closure by both the Mynx and AngioSeal VCDs to provide further insight into the risks associated with VCDs. METHODS: All adult patients who underwent deployment of either a Mynx or AngioSeal VCD and subsequently underwent repeat angiography within the next 30 days between 1 July 2010 and 1 April 2011 were reviewed...
March 2013: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/21990828/a-prospective-randomized-single-blind-trial-of-patient-comfort-following-vessel-closure-extravascular-synthetic-sealant-closure-provides-less-pain-than-a-self-tightening-suture-vascular-compression-device
#9
RANDOMIZED CONTROLLED TRIAL
Kyle M Fargen, Brian L Hoh, J Mocco
BACKGROUND AND PURPOSE: The Mynx M5 (AccessClosure, Inc., Mountain View, California, USA), a novel vascular closure device (VCD) utilizing extravascular synthetic sealant, may effectively seal the arteriotomy while reducing the pain associated with arteriotomy closure seen with other VCDs. To date, no studies exist comparing the pain associated with deployment between differing VCDs as a primary end point. METHODS: A blinded, randomized controlled trial was performed comparing the Mynx and a popular VCD that utilizes a self-tightening suture, the Angio-Seal Evolution (St Jude Medical, St Paul, Minnesota, USA)...
September 2011: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/21142643/a-novel-method-of-ventricular-closure-following-transapical-access
#10
Shishir Murarka, Richard R Heuser
AIM: left ventricular direct access and sheath placement through a minithoracotomy has been utilized to allow minimally invasive valvular surgery. One potential problem encountered is the closure of the ventricular puncture incision in a beating heart. Our aim was to develop a sutureless closure technique that does not leave behind a foreign body exposed on the endocardial surface. MATERIALS & METHODS: we sought to evaluate this concept in vivo in the porcine model...
November 2010: Future Cardiology
https://www.readbyqxmd.com/read/21127366/review-of-vascular-closure-devices
#11
REVIEW
Bryan G Schwartz, Steven Burstein, Christina Economides, Robert A Kloner, David M Shavelle, Guy S Mayeda
Vascular access-site complications are an important cause of morbidity following catheterization procedures. Manual compression is the "gold standard" in achieving hemostasis of an arteriotomy site; however, manual compression is limited by the need to interrupt anticoagulation, prolonged bed rest, patient discomfort and time demands for healthcare providers. Vascular closure devices (VCDs) improve patient comfort, free medical staff resources and shorten the time needed for hemostasis, ambulation and discharge...
December 2010: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/20538826/femoral-artery-complications-associated-with-the-mynx-closure-device
#12
J D Fields, K C Liu, D S Lee, S J Gonda, A Dogan, S H Gultekin, G M Nesbit, B D Petersen, S L Barnwell
BACKGROUND AND PURPOSE: Devices to close a femoral arteriotomy are frequently used after catheterization for interventional radiology and cardiac procedures to decrease the time to hemostasis and ambulation and, potentially, to decrease local complications. The Mynx vascular closure device uses a sealant designed to occlude the access tract, resulting in hemostasis. MATERIALS AND METHODS: We retrospectively reviewed all cases in which the Mynx device was used and for which follow-up angiography was available...
October 2010: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/20484072/successful-reduction-of-surgeries-secondary-to-arterial-access-site-complications-a-retrospective-review-at-a-single-center-with-an-extravascular-closure-device
#13
Sonya Noor, Susan Meyers, Richard Curl
BACKGROUND: Access site complications requiring emergent surgery following femoral catheterization expose patients to additional morbidities and mortality. We observed a significant decrease in such surgeries after the Mynx device was introduced. METHODS: A retrospective review of surgeries performed as a complication of 6F & 7F femoral cardiac and peripheral catheterization was done. Rates of surgeries among 3 closure methods were compared during the study period July 2006 to July 2008 (Mynx, AngioSeal, and manual/mechanical compression)...
July 2010: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/20351388/vascular-complications-after-percutaneous-coronary-intervention-following-hemostasis-with-the-mynx-vascular-closure-device-versus-the-angioseal-vascular-closure-device
#14
COMPARATIVE STUDY
Shah Azmoon, Anthony L Pucillo, Wilbert S Aronow, Ramin Ebrahimi, Joseph Vozzolo, Archana Rajdev, Kumar Kalapatapu, Jae H Ro, Craig Hjemdahl-Monsen
UNLABELLED: We investigated the prevalence of vascular complications after PCI following hemostasis in 190 patients (67% men and 33% women, mean age 64 years) treated with the AngioSeal vascular closure device (St. Jude Medical, Austin, Texas) versus 238 patients (67% men and 33% women, mean age 64 years) treated with the Mynx vascular closure device (AccessClosure, Mountain View, California). RESULTS: Death, myocardial infarction or stroke occurred in none of the 190 patients (0%) treated with the AngioSeal versus none of 238 patients (0%) treated with the Mynx...
April 2010: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/19708082/popliteal-artery-embolization-with-the-mynx-closure-device
#15
M Ashequl Islam, Anil K George, Marc Norris
Several different arterial puncture closure devices are available for use after cardiovascular procedures. The main advantages include decrease need of manual compression, reduce patient discomfort, and the time to ambulation. Access site complications are not rare after vascular closure device use. We report a case of popliteal artery embolization after using an extravascular water soluble plug-mediated vascular puncture closure device.
January 1, 2010: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/19494406/acute-evaluation-of-the-mynx-vascular-closure-device-during-arterial-re-puncture-in-an-ovine-model
#16
Joseph M Garasic, Linda Marin, R David Anderson
BACKGROUND: The Mynx vascular closure device (VCD) (AccessClosure, Inc., Mountain View, California) is used for extravascular closure of the common femoral artery (CFA) after diagnostic or interventional endovascular procedures. Although it is common clinical practice to re-puncture a CFA, for some VCDs, acute repuncture is discouraged, while for other VCDs the safety of direct re-puncture through a previously placed VCD is still in question. The objective of this preclinical study was to evaluate the acute performance of the Mynx device where direct re-puncture has occurred through the hydrogel sealant, followed by delivery of a second Mynx device to close the reaccess puncture site...
June 2009: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/18973504/a-novel-technique-for-14-french-arteriotomy-closure-after-percutaneous-aortic-valvuloplasty-using-two-mynx-closure-devices
#17
Ethan C Korngold, Ignacio Inglessis, Joseph M Garasic
Management of large bore arterial access sites often represents a challenge during interventional procedures, and usually requires prolonged manual compression, though suture-mediated closure techniques have been described. We report our experience in using the Mynx vascular closure device to close a 14 French femoral arteriotomy in two patients undergoing percutaneous balloon aortic valvuloplasty.
April 2009: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/17960627/the-safety-and-efficacy-of-an-extravascular-water-soluble-sealant-for-vascular-closure-initial-clinical-results-for-mynx
#18
MULTICENTER STUDY
D Scheinert, H Sievert, M A Turco, A Schmidt, K E Hauptmann, R Mueller, D Dadourian, H Krankenberg, E Grube
OBJECTIVE: The purpose of this study was to evaluate the hemostatic efficacy and safety of the Mynx extravascular sealant for femoral artery closure. BACKGROUND: The Mynx device is an extra-arterial vascular closure technology utilizing a water-soluble, porous, polyethylene glycol matrix that immediately seals the arteriotomy by rapidly absorbing subcutaneous fluids and expanding in the tissue tract and then, resorbs within 30 days. METHODS: The Mynx study was a prospective, multicenter, single-arm clinical investigation conducted at five European centers...
November 1, 2007: Catheterization and Cardiovascular Interventions
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