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https://www.readbyqxmd.com/read/29790327/-the-effective-educational-interventions-in-the-promotion-of-self-care-in-people-with-heart-failure-a-literature-review
#1
REVIEW
Sara Alberti, Silvia Rossini
INTRODUCTION: Self-care in people with heart failure is subject of recent middle-range and short-range nursing theories and its promotion is recognized as a sensitive nursing outcome, achievable through various strategies including education. PURPOSE: To identify educational interventions that are effective in the promotion of self-care in adults and elderly people with heart failure, evaluating educational methods and tools used and their effectiveness in the medium-long term period...
January 2018: Professioni Infermieristiche
https://www.readbyqxmd.com/read/29771539/psi4numpy-an-interactive-quantum-chemistry-programming-environment-for-reference-implementations-and-rapid-development
#2
Daniel G A Smith, Lori A Burns, Dominic A Sirianni, Daniel R Nascimento, Ashutosh Kumar, Andrew M James, Jeffrey B Schriber, Tianyuan Zhang, Boyi Zhang, Adam S Abbott, Eric J Berquist, Marvin H Lechner, Leonardo A Cunha, Alexander G Heide, Jonathan M Waldrop, Tyler Y Takeshita, Asem Alenaizan, Daniel Neuhauser, Rollin A King, Andrew C Simmonett, Justin M Turney, Henry F Schaefer, Francesco A Evangelista, A Eugene DePrince, T Daniel Crawford, Konrad Patkowski, C David Sherrill
Psi4NumPy demonstrates the use of efficient computational kernels from the open-source Psi4 program through the popular NumPy library for linear algebra in Python to facilitate the rapid development of clear, understandable Python computer code for new quantum chemical methods, while maintaining a relatively low execution time. Using these tools, reference implementations have been created for a number of methods, including self-consistent field (SCF), SCF response, many-body perturbation theory, coupled-cluster theory, configuration interaction, and symmetry-adapted perturbation theory...
May 17, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29753874/simulation-of-patient-flow-in-multiple-healthcare-units-using-process-and-data-mining-techniques-for-model-identification
#3
Sergey V Kovalchuk, Anastasia A Funkner, Oleg G Metsker, Aleksey N Yakovlev
INTRODUCTION: An approach to building a hybrid simulation of patient flow is introduced with a combination of data-driven methods for automation of model identification. The approach is described with a conceptual framework and basic methods for combination of different techniques. The implementation of the proposed approach for simulation of the acute coronary syndrome (ACS) was developed and used in an experimental study. METHODS: A combination of data, text, process mining techniques, and machine learning approaches for the analysis of electronic health records (EHRs) with discrete-event simulation (DES) and queueing theory for the simulation of patient flow was proposed...
May 10, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29736598/photodissociative-cross-linking-of-non-covalent-peptide-peptide-ion-complexes-in-the-gas-phase
#4
Huong T H Nguyen, Prokopis C Andrikopoulos, Lubomír Rulíšek, Christopher J Shaffer, František Tureček
We report a gas-phase UV photodissociation study investigating non-covalent interactions between neutral hydrophobic pentapeptides and peptide ions incorporating a diazirine-tagged photoleucine residue. Phenylalanine (Phe) and proline (Pro) were chosen as the conformation-affecting residues that were incorporated into a small library of neutral pentapeptides. Gas-phase ion-molecule complexes of these peptides with photo-labeled pentapeptides were subjected to photodissociation. Selective photocleavage of the diazirine ring at 355 nm formed short-lived carbene intermediates that underwent cross-linking by insertion into H-X bonds of the target peptide...
May 7, 2018: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/29720358/translating-behavior-change-principles-into-a-blended-exercise-intervention-for-older-adults-design-study
#5
Sumit Mehra, Bart Visser, Tessa Dadema, Jantine van den Helder, Raoul Hh Engelbert, Peter Jm Weijs, Ben Ja Kröse
BACKGROUND: Physical activity can prevent or delay age-related impairments and prolong the ability of older adults to live independently. Community-based programs typically offer classes where older adults can exercise only once a week under the guidance of an instructor. The health benefits of such programs vary. Exercise frequency and the duration of the program play a key role in realizing effectiveness. An auxiliary home-based exercise program can provide older adults the opportunity to exercise more regularly over a prolonged period of time in the convenience of their own homes...
May 2, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29712427/beyond-gene-transfection-with-methacrylate-based-polyplexes-the-influence-of-the-amino-substitution-pattern
#6
Ulrich S Schubert, Tanja Bus, Martin Reifarth, Johannes C Brendel, Stephanie Hoeppener, Anja Traeger, Anne-Kristin Trützschler
Methacrylate-based polymers represent promising non-viral gene delivery vectors, since they offer a large variety of polymer architectures and functionalities, which are beneficial for specific demands in gene delivery. In combination with controlled radical polymerization techniques, such as the reversible addition-fragmentation chain transfer polymerization, the synthesis of well-defined polymers is possible. In this study we prepared a library of defined linear polymers based on (2-aminoethyl)-methacrylate (AEMA), N-methyl-(2-aminoethyl)-methacrylate (MAEMA) and N,N-dimethyl-(2-aminoethyl)-methacrylate (DMAEMA) monomers, bearing pendant primary, secondary and tertiary amino groups, and investigated the influence of the substitution pattern on their gene delivery ability...
May 1, 2018: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/29707800/an-open-library-of-relativistic-core-electron-density-function-for-the-qtaim-analysis-with-pseudopotentials
#7
Wenli Zou, Ziyu Cai, Jiankang Wang, Kunyu Xin
Based on two-component relativistic atomic calculations, a free electron density function (EDF) library has been developed for nearly all the known ECPs of the elements Li (Z = 3) up to Ubn (Z = 120), which can be interfaced into modern quantum chemistry programs to save the .wfx wavefunction file. The applicability of this EDF library is demonstrated by the analyses of the quantum theory of atoms in molecules (QTAIM) and other real space functions on HeCuF, PtO42+, OgF4 , and TlCl3 (DMSO)2 . When a large-core ECP is used, it shows that the corrections by EDF may significantly improve the properties of some density-derived real space functions, but they are invalid for the wavefunction-depending real space functions...
April 29, 2018: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/29701424/perioperative-family-centered-care-nursing-interventions-that-support-child-and-family-s-emotional-management
#8
Dario Antunes, Paula Diogo
INTRODUCTION: Hospitalization is a negative tonality experience for both child and family, being fear and anxiety their emotional mirror. Concerning the surgical experience, the environment, invasiveness, fear of pain, of not waking up from anaesthesia and parental separation are both causes and enhancers of child and family perioperative distress. A study concerning parent's emotional experience of child's submitted to cardiac surgery, refer guilt for their son's cardiopathy, a roller coaster of emotions, impotence and being seated on pins and needles while waiting during the surgery...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29700875/family-functioning-in-the-context-of-an-adult-family-member-with-illness-a-concept-analysis
#9
Yingzi Zhang
AIM: To describe and explain how the concept of family functioning has been used in the targeted sample of health literature on adult family members with illness. BACKGROUND: Understanding the influence of illness on family functioning is central to the provision of patient- and family-centered care. There is lack of consistency in utilizing family functioning which creates confusion about the concept and can interfere with theory development in nursing science...
April 27, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29688430/regulation-of-large-number-of-weak-targets-new-insights-from-twin-micrornas
#10
Yixin Zhao, Pei Lin, Zhongqi Liufu, Hao Yang, Yang Lyu, Xu Shen, Chung-I Wu, Tian Tang
Each animal microRNA (miRNA) targets many genes for repression. Down-regulation of most of these targets is weak and has no detectable individual phenotypic effect. Whether this extensive weak repression is biologically relevant is a central issue in the debate on miRNA functionality. In the "small (target) pool" view, weak repression is non-functional and should be gradually removed during evolution. However, since the selective advantage of removing individual targets is small, testing this hypothesis is a challenge...
April 23, 2018: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29688014/machine-learning-energy-gaps-of-porphyrins-with-molecular-graph-representations
#11
Zheng Li, Noushin Omidvar, Wei Shan Chin, Esther Robb, Amanda J Morris, Luke E K Achenie, Hongliang Xin
Molecular functionalization of porphyrins opens countless new opportunities in tailoring their physicochemical properties for light-harvesting applications. However, the immense materials space spanned by a vast number of substituent ligands and chelating metal ions prohibits high-throughput screening of combinatorial libraries. In this work, machine learning algorithms equipped with the domain knowledge of chemical graph theory were employed for predicting the energy gaps of >12000 porphyrins from the Computational Materials Repository...
April 24, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29656079/theory-and-practice-of-using-solvent-paramagnetic-relaxation-enhancement-to-characterize-protein-conformational-dynamics
#12
Zhou Gong, Charles D Schwieters, Chun Tang
Paramagnetic relaxation enhancement (PRE) has been established as a powerful tool in NMR for investigating protein structure and dynamics. The PRE is usually measured with a paramagnetic probe covalently attached at a specific site of an otherwise diamagnetic protein. The present work provides the numerical formulation for probing protein structure and conformational dynamics based on the solvent PRE (sPRE) measurement, using two alternative approaches. An inert paramagnetic cosolute randomly collides with the protein, and the resulting sPRE manifests the relative solvent exposure of protein nuclei...
April 12, 2018: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/29625623/facilitators-and-barriers-to-the-delivery-of-school-based-smoking-prevention-interventions-for-children-and-young-people-a-protocol-for-a-systematic-review-of-qualitative-studies
#13
Fiona Dobbie, Kathryn Angus, Hannah Littlecott, Karen Allum, Valerie Wells, Amanda Amos, Sally Haw, Linda Bauld
BACKGROUND: Despite a decline in child and adult smoking prevalence, young people who smoke (even occasionally) can rapidly become addicted to nicotine, with most adult smokers initiating smoking before they are 18. Schools have long been a popular setting to deliver youth smoking prevention interventions, but evidence of the effectiveness of school-based prevention programmes is mixed, and outcomes vary by the type of programme delivered. Existing systematic reviews that explore the factors contributing to the success or failure of school-based smoking prevention programmes often exclude qualitative studies, due to a focus on intervention effectiveness which qualitative research cannot answer...
April 6, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29608554/specter-linear-deconvolution-for-targeted-analysis-of-data-independent-acquisition-mass-spectrometry-proteomics
#14
Ryan Peckner, Samuel A Myers, Alvaro Sebastian Vaca Jacome, Jarrett D Egertson, Jennifer G Abelin, Michael J MacCoss, Steven A Carr, Jacob D Jaffe
Mass spectrometry with data-independent acquisition (DIA) is a promising method to improve the comprehensiveness and reproducibility of targeted and discovery proteomics, in theory by systematically measuring all peptide precursors in a biological sample. However, the analytical challenges involved in discriminating between peptides with similar sequences in convoluted spectra have limited its applicability in important cases, such as the detection of single-nucleotide polymorphisms (SNPs) and alternative site localizations in phosphoproteomics data...
April 2, 2018: Nature Methods
https://www.readbyqxmd.com/read/29603550/the-links-between-adult-attachment-and-post-traumatic-stress-a-systematic-review
#15
REVIEW
Natalie Barazzone, Ines Santos, John McGowan, Eloise Donaghay-Spire
PURPOSE: The theory of attachment has informed our understanding of survival and well-being throughout the lifespan. There is a growing interest in the relationship between attachment and symptoms of post-traumatic stress (PTS). Emerging evidence points to important links between attachment and PTS, yet current theoretical and clinical understandings of PTS symptoms and attachment remain relatively disparate. The current systematic review aimed to synthesize, describe, and critique evidence demonstrating the links between attachment and PTS in adults...
March 30, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29600955/finding-fractal-networks-in-literature
#16
Havard R Glattre, Eystein Glattre
This paper is about how fractal connections between words can be identified and hidden fractal word-networks uncovered in corpus texts. The basis for this 'search-and-find' procedure is the hypothesis Complexity Connections in Corpuses (CCIC) consisting of four separate sub-hypotheses, each the basis of a procedure for uncovering a special part of such networks. The validity and applicability of CCIC are demonstrated by showing that each sub-hypothesis holds good for twenty-four masterpieces, selected from the world's great library of novels and treatises...
April 2018: Nonlinear Dynamics, Psychology, and Life Sciences
https://www.readbyqxmd.com/read/29600234/prophylactic-salpingectomy-and-ovarian-cancer-an-evidence-based-analysis
#17
Tricia Dewi Anggraeni, Adly Nanda Al Fattah, Raymond Surya
Introduction: One of the ovarian carcinogenesis theories was the presence of premalignant cells in the epithelium of the fallopian tube. Therefore, the prophylactic salpingectomy during benign gynecological surgery is now expected as the attempt to reduce the ovarian cancer incidence. We studied the effect of prophylactic bilateral salpingectomy (PBS) in reducing the ovarian cancer incidence. Methods: This evidence-based report resulted from critical appraisal of 5 articles...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29571002/multiuser-virtual-worlds-in-healthcare-education-a-systematic-review
#18
REVIEW
Sok Ying Liaw, Guiller Augustin C Carpio, Ying Lau, Seng Chee Tan, Wee Shiong Lim, Poh Sun Goh
BACKGROUND: The use of multiuser virtual worlds (MUVWs) for collaborative learning has generated interest among healthcare educators. Published evidence to support its use is growing, but none has synthesized the evidence to guide future work. OBJECTIVE: This study sought to provide a comprehensive and systematic evaluation of MUVWs in healthcare education. DESIGN: A systematic review METHODS: A systematic search of five databases including CINAHL, Cochrane library, EMBASE, PubMed, and Scopus, was conducted from inception up to January 2017...
February 2, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29530422/focused-psychosocial-interventions-for-children-in-low-resource-humanitarian-settings-a-systematic-review-and-individual-participant-data-meta-analysis
#19
Marianna Purgato, Alden L Gross, Theresa Betancourt, Paul Bolton, Chiara Bonetto, Chiara Gastaldon, James Gordon, Paul O'Callaghan, Davide Papola, Kirsi Peltonen, Raija-Leena Punamaki, Justin Richards, Julie K Staples, Johanna Unterhitzenberger, Mark van Ommeren, Joop de Jong, Mark J D Jordans, Wietse A Tol, Corrado Barbui
BACKGROUND: Results from studies evaluating the effectiveness of focused psychosocial support interventions in children exposed to traumatic events in humanitarian settings in low-income and middle-income countries have been inconsistent, showing varying results by setting and subgroup (eg, age or gender). We aimed to assess the effectiveness of these interventions, and to explore which children are likely to benefit most. METHODS: We did a systematic review and meta-analysis of individual participant data (IPD) from 3143 children recruited to 11 randomised controlled trials of focused psychosocial support interventions versus waiting list...
April 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29495725/passive-acoustic-tracking-using-a-library-of-nearby-sources-of-opportunity
#20
Christopher M A Verlinden, J Sarkar, W S Hodgkiss, W A Kuperman, K G Sabra
A method of localizing unknown acoustic sources using data derived replicas from ships of opportunity has been reported previously by Verlinden, Sarkar, Hodgkiss, Kuperman, and Sabra [J. Acoust. Soc. Am, 138(1), EL54-EL59 (2015)]. The method is similar to traditional matched field processing, but differs in that data-derived measured replicas are used in place of modeled replicas and, in order to account for differing source spectra between library and target vessels, cross-correlation functions are compared instead of comparing acoustic signals directly...
February 2018: Journal of the Acoustical Society of America
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