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https://www.readbyqxmd.com/read/28185369/sensory-overload-a-concept-analysis
#1
REVIEW
Stefan Scheydt, Maria Müller Staub, Fritz Frauenfelder, Gunnar H Nielsen, Johann Behrens, Ian Needham
In the context of mental disorders sensory overload is a widely described phenomenon used in conjunction with psychiatric interventions such as removal from stimuli. However, the theoretical foundation of sensory overload as addressed in the literature can be described as insufficient and fragmentary. To date, the concept of sensory overload has not yet been sufficiently specified or analyzed. The aim of the study was to analyze the concept of sensory overload in mental health care. A literature search was undertaken using specific electronic databases, specific journals and websites, hand searches, specific library catalogues, and electronic publishing databases...
February 9, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/28162090/a-realist-review-of-mobile-phone-based-health-interventions-for-non-communicable-disease-management-in-sub-saharan-africa
#2
Daniel Opoku, Victor Stephani, Wilm Quentin
BACKGROUND: The prevalence of non-communicable diseases (NCDs) is increasing in sub-Saharan Africa. At the same time, the use of mobile phones is rising, expanding the opportunities for the implementation of mobile phone-based health (mHealth) interventions. This review aims to understand how, why, for whom, and in what circumstances mHealth interventions against NCDs improve treatment and care in sub-Saharan Africa. METHODS: Four main databases (PubMed, Cochrane Library, Web of Science, and Google Scholar) and references of included articles were searched for studies reporting effects of mHealth interventions on patients with NCDs in sub-Saharan Africa...
February 6, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28134445/interventions-for-prevention-of-bullying-in-the-workplace
#3
REVIEW
Patricia A Gillen, Marlene Sinclair, W George Kernohan, Cecily M Begley, Ans G Luyben
BACKGROUND: Bullying has been identified as one of the leading workplace stressors, with adverse consequences for the individual employee, groups of employees, and whole organisations. Employees who have been bullied have lower levels of job satisfaction, higher levels of anxiety and depression, and are more likely to leave their place of work. Organisations face increased risk of skill depletion and absenteeism, leading to loss of profit, potential legal fees, and tribunal cases. It is unclear to what extent these risks can be addressed through interventions to prevent bullying...
January 30, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28128950/naphthablins-b-and-c-meroterpenoids-identified-from-the-marine-sediment-derived-streptomyces-sp-cp26-58-using-hela-cell-based-cytological-profiling
#4
Hana Martucci, Scott E Campit, Stephanie R Gee, Walter M Bray, Trevor Gokey, A King Cada, Ten-Yang Yen, Katsuhiko Minoura, Anton B Guliaev, R Scott Lokey, Taro Amagata
HeLa cell-based cytological profiling (CP) was applied to an extract library of marine sediment-derived actinomycetes to discover new cytotoxic secondary metabolites. Among the hit strains, Streptomyces sp. CP26-58 was selected for further investigation to identify its cytotoxic metabolites. CP revealed that the known ionophore tetronasin (1) was responsible for the cytotoxic effect found in the extract. Furthermore, three naphthoquinone meroterpenoids, naphthablin A (2) and two new derivatives designated as naphthablins B (3) and C (4), were isolated from other cytotoxic fractions...
January 27, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28121021/interventions-for-dysarthria-due-to-stroke-and-other-adult-acquired-non-progressive-brain-injury
#5
REVIEW
Claire Mitchell, Audrey Bowen, Sarah Tyson, Zoe Butterfint, Paul Conroy
BACKGROUND: Dysarthria is an acquired speech disorder following neurological injury that reduces intelligibility of speech due to weak, imprecise, slow and/or unco-ordinated muscle control. The impact of dysarthria goes beyond communication and affects psychosocial functioning. This is an update of a review previously published in 2005. The scope has been broadened to include additional interventions, and the title amended accordingly. OBJECTIVES: To assess the effects of interventions to improve dysarthric speech following stroke and other non-progressive adult-acquired brain injury such as trauma, infection, tumour and surgery...
January 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28118011/a-general-sparse-tensor-framework-for-electronic-structure-theory
#6
Samuel Manzer, Evgeny Epifanovsky, Anna I Krylov, Martin Head-Gordon
Linear-scaling algorithms must be developed in order to extend the domain of applicability of electronic structure theory to molecules of any desired size. However, the increasing complexity of modern linear-scaling methods makes code development and maintenance a significant challenge. A major contributor to this difficulty is the lack of robust software abstractions for handling block-sparse tensor operations. We therefore report the development of a highly efficient symbolic block-sparse tensor library in order to provide access to high-level software constructs to treat such problems...
January 24, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28093364/fabrication-of-nanofibrous-electrospun-scaffolds-from-a-heterogeneous-library-of-co-and-self-assembling-peptides
#7
Mahboubeh Maleki, Antonino Natalello, Raffaele Pugliese, Fabrizio Gelain
: Self-assembling (SAPs) and co-assembling peptides (CAPs) are driving increasing enthusiasm as synthetic but biologically inspired biomaterials amenable of easy functionalization for regenerative medicine. On the other hand, electrospinning (ES) is a versatile technique useful for tailoring the nanostructures of various biomaterials into scaffolds resembling the extracellular matrices found in organs and tissues. The synergistic merging of these two approaches is a long-awaited advance in nanomedicine that has not been deeply documented so far...
January 13, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28093049/efficient-variational-approach-to-multimodal-registration-of%C3%A2-anatomical%C3%A2-and%C3%A2-functional-intra-patient-tumorous-brain-data
#8
Alvar-Ginés Legaz-Aparicio, Rafael Verdú-Monedero, Jorge Larrey-Ruiz, Juan Morales-Sánchez, Fernando López-Mir, Valery Naranjo, Ángela Bernabéu
This paper addresses the functional localization of intra-patient images of the brain. Functional images of the brain (fMRI and PET) provide information about brain function and metabolism whereas anatomical images (MRI and CT) supply the localization of structures with high spatial resolution. The goal is to find the geometric correspondence between functional and anatomical images in order to complement and fuse the information provided by each imaging modality. The proposed approach is based on a variational formulation of the image registration problem in the frequency domain...
November 29, 2016: International Journal of Neural Systems
https://www.readbyqxmd.com/read/28035955/exon-shuffling-and-origin-of-scorpion-venom-biodiversity
#9
Xueli Wang, Bin Gao, Shunyi Zhu
Scorpion venom is a complex combinatorial library of peptides and proteins with multiple biological functions. A combination of transcriptomic and proteomic techniques has revealed its enormous molecular diversity, as identified by the presence of a large number of ion channel-targeted neurotoxins with different folds, membrane-active antimicrobial peptides, proteases, and protease inhibitors. Although the biodiversity of scorpion venom has long been known, how it arises remains unsolved. In this work, we analyzed the exon-intron structures of an array of scorpion venom protein-encoding genes and unexpectedly found that nearly all of these genes possess a phase-1 intron (one intron located between the first and second nucleotides of a codon) near the cleavage site of a signal sequence despite their mature peptides remarkably differ...
December 26, 2016: Toxins
https://www.readbyqxmd.com/read/28018650/using-fisher-information-to-track-stability-in-multivariate-systems
#10
Nasir Ahmad, Sybil Derrible, Tarsha Eason, Heriberto Cabezas
With the current proliferation of data, the proficient use of statistical and mining techniques offer substantial benefits to capture useful information from any dataset. As numerous approaches make use of information theory concepts, here, we discuss how Fisher information (FI) can be applied to sustainability science problems and used in data mining applications by analysing patterns in data. FI was developed as a measure of information content in data, and it has been adapted to assess order in complex system behaviour...
November 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/27982169/primordial-and-primary-prevention-programs-for-cardiovascular-diseases-from-risk-assessment-through-risk-communication-to-risk-reduction-a-review-of-the-literature
#11
Inês Lancarotte, Moacyr Roberto Nobre
The aim of this study was to identify and reflect on the methods employed by studies focusing on intervention programs for the primordial and primary prevention of cardiovascular diseases. The PubMed, EMBASE, SciVerse Hub-Scopus, and Cochrane Library electronic databases were searched using the terms 'effectiveness AND primary prevention AND risk factors AND cardiovascular diseases' for systematic reviews, meta-analyses, randomized clinical trials, and controlled clinical trials in the English language. A descriptive analysis of the employed strategies, theories, frameworks, applied activities, and measurement of the variables was conducted...
November 1, 2016: Clinics
https://www.readbyqxmd.com/read/27943483/rapid-realist-review-of-the-evidence-achieving-lasting-change-when-mental-health-rehabilitation-staff-undertake-recovery-oriented-training
#12
REVIEW
M Gee, S Bhanbrho, S Cook, H Killaspy
AIM: To identify the factors contributing to lasting change in practice following a recovery-based training intervention for inpatient mental health rehabilitation staff. BACKGROUND: Staff training may help nurses and other staff groups in inpatient mental health rehabilitative settings to increase their recovery-oriented practice. There are no published reviews on the effectiveness of such training and few long-term evaluations. This review informed a realist evaluation of a specific intervention ('GetREAL')...
December 10, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27942248/foundations-of-reusable-and-interoperable-facet-models-using-category-theory
#13
Daniel R Harris
Faceted browsing has become ubiquitous with modern digital libraries and online search engines, yet the process is still difficult to abstractly model in a manner that supports the development of interoperable and reusable interfaces. We propose category theory as a theoretical foundation for faceted browsing and demonstrate how the interactive process can be mathematically abstracted. Existing efforts in facet modeling are based upon set theory, formal concept analysis, and light-weight ontologies, but in many regards, they are implementations of faceted browsing rather than a specification of the basic, underlying structures and interactions...
October 2016: Inf Syst Front
https://www.readbyqxmd.com/read/27930689/determination-of-a-screening-metric-for-high-diversity-dna-libraries
#14
Nicholas J Guido, Steven Handerson, Elaine M Joseph, Devin Leake, Li A Kung
The fields of antibody engineering, enzyme optimization and pathway construction rely increasingly on screening complex variant DNA libraries. These highly diverse libraries allow researchers to sample a maximized sequence space; and therefore, more rapidly identify proteins with significantly improved activity. The current state of the art in synthetic biology allows for libraries with billions of variants, pushing the limits of researchers' ability to qualify libraries for screening by measuring the traditional quality metrics of fidelity and diversity of variants...
2016: PloS One
https://www.readbyqxmd.com/read/27905594/open-ended-formulation-of-self-consistent-field-response-theory-with-the-polarizable-continuum-model-for-solvation
#15
Roberto Di Remigio, Maarten T P Beerepoot, Yann Cornaton, Magnus Ringholm, Arnfinn Hykkerud Steindal, Kenneth Ruud, Luca Frediani
The study of high-order absorption properties of molecules is a field of growing importance. Quantum-chemical studies can help design chromophores with desirable characteristics. Given that most experiments are performed in solution, it is important to devise a cost-effective strategy to include solvation effects in quantum-chemical studies of these properties. We here present an open-ended formulation of self-consistent field (SCF) response theory for a molecular solute coupled to a polarizable continuum model (PCM) description of the solvent...
December 21, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27869298/informant-questionnaire-on-cognitive-decline-in-the-elderly-iqcode-for-the-early-diagnosis-of-dementia-across-a-variety-of-healthcare-settings
#16
REVIEW
Jennifer K Harrison, David J Stott, Rupert McShane, Anna H Noel-Storr, Rhiannon S Swann-Price, Terry J Quinn
BACKGROUND: The Informant Questionnaire for Cognitive Decline in the Elderly (IQCODE) is a structured interview based on informant responses that is used to assess for possible dementia. IQCODE has been used for retrospective or contemporaneous assessment of cognitive decline. There is considerable interest in tests that may identify those at future risk of developing dementia. Assessing a population free of dementia for the prospective development of dementia is an approach often used in studies of dementia biomarkers...
21, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27861942/the-ectopic-accessory-parotid-system-with-congenital-cheek-fistula-an-overview-and-current-update
#17
REVIEW
Mainak Dutta
OBJECTIVE: This review attempts to provide a comprehensive, updated overview of the ectopic accessory parotid system (EAPS) from clinical and developmental perspectives and investigates its eligibility to be included in the oculo-auriculo-vertebral spectrum (OAVS). REVIEW METHODS: Results of the keyword-based search in the PubMed/MEDLINE, Google Scholar, LILACS, and Cochrane Library were subjected to the given inclusion and exclusion criteria that corroborated with the definition of EAPS...
November 12, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27769955/do-web-based-interventions-improve-well-being-in-type-2-diabetes-a-systematic-review-and-meta-analysis
#18
Michelle Hadjiconstantinou, Jo Byrne, Danielle H Bodicoat, Noelle Robertson, Helen Eborall, Kamlesh Khunti, Melanie J Davies
BACKGROUND: Poor diabetes self-care can have a negative impact on psychological well-being and quality of life. Given the scarcity of traditional psychological support and the barriers to uptake of and attendance at face-to-face education programs, Web-based interventions are becoming a popular approach to provide an additional platform for psychological support in long-term conditions. However, there is limited evidence to assess the effect of Web-based psychological support in people with type 2 diabetes...
October 21, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27701844/generation-of-accurate-peptide-retention-data-for-targeted-and-data-independent-quantitative-lc-ms-analysis-chromatographic-lessons-in-proteomics
#19
Oleg V Krokhin, Vic Spicer
The emergence of data-independent quantitative LC-MS/MS analysis protocols further highlights the importance of high-quality reproducible chromatographic procedures. Knowing, controlling and being able to predict the effect of multiple factors that alter peptide RP-HPLC separation selectivity is critical for successful data collection for the construction of ion libraries. Proteomic researchers have often regarded RP-HPLC as a "black box", while vast amount of research on peptide separation is readily available...
December 2016: Proteomics
https://www.readbyqxmd.com/read/27641740/women-s-mental-health-and-intimate-partner-violence-following-natural-disaster-a-scoping-review
#20
Sue Anne Bell, Lisa A Folkerth
: Introduction Survivors of natural disasters in the United States experience significant health ramifications. Women particularly are vulnerable to both post-disaster posttraumatic stress disorder (PTSD) and depression, and research has documented that these psychopathological sequelae often are correlated with increased incidence of intimate partner violence (IPV). Understanding the link between these health concerns is crucial to informing adequate disaster response and relief efforts for victims of natural disaster...
December 2016: Prehospital and Disaster Medicine
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