keyword
https://read.qxmd.com/read/38645131/cortical-tau-aggregation-patterns-associated-with-apraxia-in-alzheimer-s-disease
#1
Gérard N Bischof, Elena Jaeger, Kathrin Giehl, Frank Jessen, Oezguer A Onur, Sid O'Bryant, Esra Kara, Peter H Weiss, Alexander Drzezga
OBJECTIVES: Apraxia is a core feature of Alzheimer's disease, but the pathomechanism of this characteristic symptom is not well understood. Here, we systematically investigated apraxia profiles in a well-defined group of patients with Alzheimer's disease (AD; N=32) who additionally underwent PET imaging with the second-generation tau PET tracer [18F]PI-2620. We hypothesized that specific patterns of tau pathology might be related to apraxic deficits. METHODS: Patients (N=32) with a biomarker-confirmed diagnosis of Alzheimer's disease were recruited in addition to a sample cognitively unimpaired controls (CU 1 ; N=41)...
April 10, 2024: medRxiv
https://read.qxmd.com/read/38640248/programmable-multiphoton-quantum-interference-in-a-single-spatial-mode
#2
JOURNAL ARTICLE
Lorenzo Carosini, Virginia Oddi, Francesco Giorgino, Lena M Hansen, Benoit Seron, Simone Piacentini, Tobias Guggemos, Iris Agresti, Juan C Loredo, Philip Walther
The interference of nonclassical states of light enables quantum-enhanced applications reaching from metrology to computation. Most commonly, the polarization or spatial location of single photons are used as addressable degrees of freedom for turning these applications into praxis. However, the scale-up for the processing of a large number of photons of these architectures is very resource-demanding due to the rapidly increasing number of components, such as optical elements, photon sources, and detectors...
April 19, 2024: Science Advances
https://read.qxmd.com/read/38639817/-nationally-standardized-broad-consent-in-practice-initial-experiences-current-developments-and-critical-assessment
#3
JOURNAL ARTICLE
Sven Zenker, Daniel Strech, Roland Jahns, Gabriele Müller, Fabian Prasser, Christoph Schickhardt, Georg Schmidt, Sebastian C Semler, Eva Winkler, Johannes Drepper
BACKGROUND: The digitalization in the healthcare sector promises a secondary use of patient data in the sense of a learning healthcare system. For this, the Medical Informatics Initiative's (MII) Consent Working Group has created an ethical and legal basis with standardized consent documents. This paper describes the systematically monitored introduction of these documents at the MII sites. METHODS: The monitoring of the introduction included regular online surveys, an in-depth analysis of the introduction processes at selected sites, and an assessment of the documents in use...
April 19, 2024: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://read.qxmd.com/read/38636292/the-efficacy-of-sacituzumab-govitecan-and-trastuzumab-deruxtecan-on-stable-and-active-brain-metastases-in-metastatic-breast-cancer-patients-a-multicenter-real-world-analysis
#4
JOURNAL ARTICLE
D Dannehl, D Jakob, F Mergel, A Estler, T Engler, L Volmer, M-L Frevert, S Matovina, A Englisch, C M Tegeler, A Rohner, A Seller, M Hahn, K Pfister, A Fink, I Popp, S Lorenz, G Tabatabai, I Juhasz-Böss, W Janni, S Brucker, F-A Taran, A Hartkopf, H Schäffler
BACKGROUND: Fifteen to thirty percent of all patients with metastatic breast cancer (MBC) develop brain metastases (BCBMs). Recently, the antibody-drug conjugates (ADCs) sacituzumab govitecan (SG) and trastuzumab deruxtecan (T-DXd) have shown to be highly effective in the treatment of MBC. However, there are only limited data whether these macromolecules are also effective in patients with BCBMs. We therefore aimed to examine the efficacy of SG and T-DXd in patients with stable and active BCBMs in a multicenter real-world analysis...
April 17, 2024: ESMO Open
https://read.qxmd.com/read/38634391/-not-available
#5
JOURNAL ARTICLE
Maike Garbade, Cedric Sachser, Elisa Pfeiffer
The Current Status of the Intercultural Opening of the Psychiatric-Psychotherapeutic Care for Children and Adolescents from the Perspective of Professionals Children and adolescents with a migration background have a high demand for psychiatricpsychotherapeutic care in Germany. Nevertheless, they often do not receive the care needed, despite the Intercultural Opening, which aims at adjusting the services to their needs.The aim of the study is to get insights in the current status of the Intercultural Opening of the psychiatric- psychotherapeutic care system by examining the perspectives and needs of the staff working with this vulnerable population...
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634390/-not-available
#6
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634389/-not-available
#7
JOURNAL ARTICLE
Gerolf Renner, Anne Schroeder, Dieter Irblich
How Does the Kaufman Assessment Battery for Children-II Stand the Test of Clinical Practice? Findings in 7- To 12-Year-Old Children Reliability and validity of the KABC-II were investigated in 646 children aged 7 to 12 years who had been assessed in four social pediatric centers and one pediatric clinic in Germany due to developmental, behavioral, or emotional disorders.The reliability of the global scales Fluid-Crystallized-Index (FCI) and Mental Processing Index (MPI) proved to be very high in all age groups, with values ≥ ...
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634388/-not-available
#8
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634387/-not-available
#9
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634386/-not-available
#10
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634385/-not-available
#11
JOURNAL ARTICLE
Olivia Creutz, Tijs Bolz, Menno Baumann
Child-to-Parent Violence -The Blind Spot in Research on Family Violence? A Systematic Review Child-to-parent violence (CPV) is a phenomenon that has received little attention in the German scientific community. With this paper, the authors present the international state of research in the context of a systematic review. By means of a search a dataset of 317 scientific publications for the period 2012-2022 was identified at August 2022. After applying the inclusion and exclusion criteria, 14 studies were finally defined and analyzed in detail...
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38634384/-not-available
#12
JOURNAL ARTICLE
Gabriele Meyer-Enders, Gerd Lehmkuhl
Children Create Narratives - First Experience with the Revised Sceno-2 Test The Sceno Test, created by Gerthild von Staabs, has been in use and has been useful in its original version for more than 80 years. It has now undergone a major revision.The test will retain its relevance as a projective diagnostic procedure offering children and juveniles opportunities to design scenes and to voice narratives coming along with them. It can serve as an instrument encompassing all therapeutic approaches to explore infantile wishes, perceptions, and interpretations and can provide, as intended by Gerthild von Staabs, indications of family dynamics...
March 2024: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://read.qxmd.com/read/38630858/phronesis-recognising-a-neglected-dimension-of-knowledge-within-occupational-therapy-research
#13
JOURNAL ARTICLE
Aileen Bergström, Margarita Mondaca, Ingeborg Nilsson, Susanne Guidetti, Lena Rosenberg
BACKGROUND: Phronesis is a way of knowing, implying wisdom, experiences, and reflections that guide our judgements. Phronesis, important for learning, is a neglected form of knowledge when applied to research. AIM: To examine how phronesis is conceptualised and practiced in three research projects. METHOD: Data from eight interviews with researchers involved in three research projects was generated. The interview material was analysed. A theoretical matrix of contemporary understanding of phronesis was applied to the material...
January 2024: Scandinavian Journal of Occupational Therapy
https://read.qxmd.com/read/38629797/localizing-apraxia-in-corticobasal-syndrome-a-morphometric-mri-study
#14
JOURNAL ARTICLE
Vasilios C Constantinides, George P Paraskevas, Georgios Velonakis, Leonidas Stefanis, Elisabeth Kapaki
Apraxia localization has relied on voxel-based, lesion-symptom mapping studies in left hemisphere stroke patients. Studies on the neural substrates of different manifestations of apraxia in neurodegenerative disorders are scarce. The primary aim of this study was to look into the neural substrates of different manifestations of apraxia in a cohort of corticobasal syndrome patients (CBS) by use of cortical thickness. Twenty-six CBS patients were included in this cross-sectional study. The Goldenberg apraxia test (GAT) was applied...
April 1, 2024: Cerebral Cortex
https://read.qxmd.com/read/38621827/-what-do-we-need-for-the-individual-case
#15
JOURNAL ARTICLE
Gerhard Längle
No abstract text is available yet for this article.
April 2024: Psychiatrische Praxis
https://read.qxmd.com/read/38608668/-demstepcare-risk-stratified-support-for-primary-care-based-dementia-care-evaluation-from-general-practitioner-s-view
#16
JOURNAL ARTICLE
Katharina Geschke, Julian Wangler, Fabian Klein, Alexandra Wuttke-Linnemann, Erik Farin-Glattacker, Michael Löhr, Michael Jansky, Andreas Fellgiebel
OBJECTIVE: The innovation fund project DemStepCare aimed to optimize multi-professional care through case management, risk stratification, and crisis outpatient clinic. Here, the evaluation results from the perspective of the general practitioners are presented. METHODS: A quantitative survey was carried out at three time points regarding acceptance, benefit assessment and sensitivity to dementia of the general practitioners. In addition, qualitative interviews were conducted...
April 12, 2024: Psychiatrische Praxis
https://read.qxmd.com/read/38598821/story-sharing-facilitation-guide-an-educational-strategy-to-develop-strengths-based-nursing-and-healthcare-leaders
#17
JOURNAL ARTICLE
Michele Durrant, Laurie N Gottlieb
BACKGROUND: A reflective praxis process has been developed to facilitate story-sharing, an educational strategy grounded in narrative pedagogy. METHOD: This article describes this strategy, the Story-Sharing Facilitation Guide (SSFG). The guide allows educators to facilitate the telling of a story that often triggers a memory of similar or contrasting experiences. Sharing stories helps learners find personal and professional meaning, develop new insights, and revise actions...
April 12, 2024: Journal of Nursing Education
https://read.qxmd.com/read/38592859/folk-knowledge-and-perceptions-about-the-use-of-wild-fruits-and-vegetables-cross-cultural-knowledge-in-the-pipli-pahar-reserved-forest-of-okara-pakistan
#18
JOURNAL ARTICLE
Sadia Jabeen, Fahim Arshad, Nidaa Harun, Muhammad Waheed, Saud Alamri, Shiekh Marifatul Haq, Ivana Vitasović-Kosić, Kaneez Fatima, Abdul Shakoor Chaudhry, Rainer W Bussmann
Wild fruits and vegetables (WFVs) have been vital to local communities for centuries and make an important contribution to daily life and income. However, traditional knowledge of the use of wild fruits is at risk of being lost due to inadequate documentation. This study aimed to secure this knowledge through intermittent field visits and a semi-structured questionnaire. Using various ethnobotanical data analysis tools and SPSS (IBM 25), this study identified 65 WFV species (52 genera and 29 families). These species, mostly consumed as vegetables (49%) or fruits (43%), were predominantly herbaceous (48%) in wild and semi-wild habitats (67%)...
March 14, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38588715/-correction-intradermal-and-serologic-testing-for-insect-bite-hypersensitivity-in-a-dahomey-ox
#19
JOURNAL ARTICLE
Laura Schäfer, Lydia Tatjana Stahl, Marlene Sickinger, Nina Thom
No abstract text is available yet for this article.
February 2024: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://read.qxmd.com/read/38581512/-not-available
#20
JOURNAL ARTICLE
Kathrin Handschuh
No abstract text is available yet for this article.
April 2024: MMW Fortschritte der Medizin
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