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https://www.readbyqxmd.com/read/28301532/factors-associated-with-study-completion-in-patients-with-premature-acute-coronary-syndrome
#1
Anthony W Austin, Roxanne Pelletier, Louise Pilote, Doreen M Rabi
BACKGROUND: Factors associated with study completion in younger adults are not well understood. This study sought to describe psychosocial, clinical, and demographic features associated with completion of a study of men and women with premature acute coronary syndrome. METHODS: As part of the GENdEr and Sex determInantS of cardiovascular disease: From bench to beyond-Premature Acute Coronary Syndrome (GENESIS-PRAXY) study, demographic, psychosocial, and clinical variables were assessed in 1213 patients hospitalized for acute coronary syndrome (≤ 55 years; 30% women)...
2017: PloS One
https://www.readbyqxmd.com/read/28296469/praxis-skills-and-executive-function-in-children-with-neurofibromatosis-type-1
#2
Chrystelle Remigereau, Arnaud Roy, Orianne Costini, Sébastien Barbarot, Marie Bru, Didier Le Gall
This study aimed at examining motor and ideomotor praxis skills in children with neurofibromatosis type 1 (NF1). The impact of executive dysfunction, frequently described in children with NF1, on the expression of praxis impairments was also studied. Eighteen children with NF1 were included and matched with 20 control children for age (7-14 years), sex, laterality, and parental education level. Both groups of children underwent an assessment based on cognitive models of apraxia including visuomotor tasks, executive tests, and everyday life questionnaires...
March 15, 2017: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/28295501/when-i-say%C3%A2-praxis
#3
Stella L Ng, Sarah R Wright
No abstract text is available yet for this article.
March 10, 2017: Medical Education
https://www.readbyqxmd.com/read/28277283/toward-a-functional-neuroanatomy-of-semantic-aphasia-a-history-and-ten-new-cases
#4
Olga Dragoy, Yulia Akinina, Nina Dronkers
Almost 70 years ago, Alexander Luria incorporated semantic aphasia among his aphasia classifications by demonstrating that deficits in linking the logical relationships of words in a sentence could co-occur with non-linguistic disorders of calculation, spatial gnosis and praxis deficits. In line with his comprehensive approach to the assessment of language and other cognitive functions, he argued that deficits in understanding semantically reversible sentences and prepositional phrases, for example, were in line with a single neuropsychological factor of impaired spatial analysis and synthesis, since understanding such grammatical relationships would also draw on their spatial relationships...
October 6, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28257975/rapid-and-sensitive-detection-of-microrna-via-the-capture-of-fluorescent-dyes-loaded-albumin-nanoparticles-around-functionalized-magnetic-beads
#5
Tianxiang Wei, Dan Du, Zhaoyin Wang, Weiwei Zhang, Yuehe Lin, Zhihui Dai
MicroRNAs (miRNAs) play important roles in gene regulation and cancer development. Nowadays, it is still a challenge to detect low-abundance miRNAs. Here, we present a magnetic fluorescent miRNA sensing system for the rapid and sensitive detection of miRNAs from cell lysates and serum samples. In this system, albumin nanoparticles (Alb NPs) were prepared from inherent biocompatible bovine serum albumin (BSA). A large number of fluorescent dyes were loaded into Alb NPs to make Alb NPs serve as signal molecular nanocarriers for signal amplification...
February 27, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28252853/pathogenese-von-wundheilungsst%C3%A3-rungen-bei-%C3%A3-lteren-patienten
#6
Evgenia Makrantonaki, Meinhard Wlaschek, Karin Scharffetter-Kochanek
Ältere Menschen sind für Wundheilungsstörungen und chronische Wunden am anfälligsten, insbesondere für venöse Beinulzera, Dekubitalulzera und diabetische Fußulzera. Jedoch sollten bei der diagnostischen Abklärung chronischer Wunden weitere altersassoziierte Krankheiten in Betracht gezogen werden. Ein besseres Verständnis der an Wundheilungsstörungen beteiligten Pathomechanismen ist wichtig für die Bewältigung der Schwierigkeiten bei der Behandlung chronischer Wunden. In den letzten Jahrzehnten wurden beachtliche Fortschritte bei zukunftsweisenden Therapien chronischer Wunden erzielt...
March 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28225838/-mental-simulation-in-frontotemporal-dementia
#7
Daniel G Politis, Wanda Y Rubinstein, María E Tabernero
There is a common network for perception and execution of actions necessary for the acquisition of Theory of Mind, and the mirror neuron system could be the neural substrate. OBJECTIVE: To study the presence of apraxia and their relationship to Theory of Mind in patients with behavioral variant of Frontotemporal Dementia. METHODS: 24 patients were assessed, and the cognitive praxis assessment battery and theory of mind were administered. RESULTS: All the tasks of the cognitive praxis assessment battery showed a significant correlation with the first order False Believe task, while Faces Test showed correlations with all the battery tasks except Auditory verbal income...
May 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28214841/drug-dosing-and-estimated-renal-function-any-step-forward-from-effersoe
#8
Mads Hornum, Bo Feldt-Rasmussen
Drug dosing in accordance with the renal function is a long-standing challenge to clinicians. For many years it has been evident that in many clinical situations there is no easy way to correctly dose any drug that is mainly cleared by the kidneys. Despite the development of many formulas for estimating the glomerular filtration rate, they all have serious shortcomings. Much effort has been put in to develop estimation formulas to evaluate the renal function as an alternative to direct methods with the aim of safely dosing drugs that are mainly cleared by the kidneys...
February 18, 2017: Nephron
https://www.readbyqxmd.com/read/28213762/association-between-cognitive-impairment-and-urinary-dysfunction-in-parkinson-s-disease
#9
Zuzanna Tkaczynska, Andrea Pilotto, Sara Becker, Susanne Gräber-Sultan, Daniela Berg, Inga Liepelt-Scarfone
Urinary dysfunction (UD) is a common non-motor feature of Parkinson's disease (PD), and might be secondary to neurodegeneration involving cortical and subcortical brain areas. The possible link between UD and cognitive deficits has never been examined in frontal cortex impairment, and is still not completely understood in PD. In the present study, 94 PD patients underwent a comprehensive motor, cognitive and non-motor assessment. It was shown that 55.3% of patients reported UD, of which 17% needed specific urological treatment...
February 17, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28205497/critical-motor-involvement-in-prediction-of-human-and-non-biological-motion-trajectories
#10
Matthieu M de Wit, Laurel J Buxbaum
OBJECTIVES: Adaptive interaction with the environment requires the ability to predict both human and non-biological motion trajectories. Prior accounts of the neurocognitive basis for prediction of these two motion classes may generally be divided into those that posit that non-biological motion trajectories are predicted using the same motor planning and/or simulation mechanisms used for human actions, and those that posit distinct mechanisms for each. Using brain lesion patients and healthy controls, this study examined critical neural substrates and behavioral correlates of human and non-biological motion prediction...
February 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28205496/planning-functional-grasps-of-simple-tools-invokes-the-hand-independent-praxis-representation-network-an-fmri-study
#11
Łukasz Przybylski, Gregory Króliczak
OBJECTIVES: Neuropsychological and neuroimaging evidence indicates that tool use knowledge and abilities are represented in the praxis representation network (PRN) of the left cerebral hemisphere. We investigated whether PRN would also underlie the planning of function-appropriate grasps of tools, even though such an assumption is inconsistent with some neuropsychological evidence for independent representations of tool grasping and skilled tool use. METHODS: Twenty right-handed participants were tested in an event-related functional magnetic resonance imaging (fMRI) study wherein they planned functionally appropriate grasps of tools versus grasps of non-tools matched for size and/or complexity, and later executed the pantomimed grasps of these objects...
February 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28195027/the-anthropo-scene-a-guide-for-the-perplexed
#12
Jamie Lorimer
The scientific proposal that the Earth has entered a new epoch as a result of human activities - the Anthropocene - has catalysed a flurry of intellectual activity. I introduce and review the rich, inchoate and multi-disciplinary diversity of this Anthropo-scene. I identify five ways in which the concept of the Anthropocene has been mobilized: scientific question, intellectual zeitgeist, ideological provocation, new ontologies and science fiction. This typology offers an analytical framework for parsing this diversity, for understanding the interactions between different ways of thinking in the Anthropo-scene, and thus for comprehending elements of its particular and peculiar sociabilities...
February 2017: Social Studies of Science
https://www.readbyqxmd.com/read/28182172/chronic-disease-self-management-support-for-persons-with-dementia-in-a-clinical-setting
#13
Joseph Elias Ibrahim, Laura J Anderson, Aleece MacPhail, Janaka Jonathan Lovell, Marie-Claire Davis, Margaret Winbolt
The burden of chronic disease is greater in individuals with dementia, a patient group that is growing as the population is aging. The cornerstone of optimal management of chronic disease requires effective patient self-management. However, this is particularly challenging in older persons with a comorbid diagnosis of dementia. The impact of dementia on a person's ability to self-manage his/her chronic disease (eg, diabetes mellitus or heart failure) varies according to the cognitive domain(s) affected, severity of impairment and complexity of self-care tasks...
2017: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/28131207/the-correlation-between-cerebral-arterial-pulsatility-and-cognitive-dysfunction-in-alzheimer-s-disease-patients
#14
Jae-Sung Lim, Jee Young Lee, Hyung-Min Kwon, Yong-Seok Lee
BACKGROUND: Potential role of vascular dysfunction has been suggested in the pathogenesis of Alzheimer's disease (AD). Previous cross-sectional studies have demonstrated relations between abnormal transcranial Doppler (TCD) parameters and cognitive impairment. We aimed to investigate the associations between longitudinal changes of TCD parameters and cognitive decline in patients with AD. METHODS: We have enrolled patients with mild to moderate AD who aged 60 to 79years...
February 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28128035/functional-plasticity-in-the-absence-of-structural-change
#15
Tal Krasovsky, Jana Landa, Orly Bar, Ahonniska-Assa Jaana, Abigail Livny, Galia Tsarfaty, Tamar Silberg
This work presents a case of a young woman with apraxia and a severe body scheme disorder, 10 years after a childhood frontal and occipitoparietal brain injury. Despite specific limitations, she is independent in performing all activities of daily living. A battery of tests was administered to evaluate praxis and body representations. Specifically, the Hand Laterality Test was used to compare RS's dynamic body representation to that of healthy controls (N = 14). Results demonstrated RS's severe praxis impairment, and the Hand Laterality Test revealed deficits in accuracy and latency of motor imagery, suggesting a significant impairment in dynamic body representation...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28107802/movement-kinematics-of-the-ipsilesional-upper-extremity-in-persons-with-moderate-or-mild-stroke
#16
Eva-Lena Bustrén, Katharina Stibrant Sunnerhagen, Margit Alt Murphy
BACKGROUND: An increasing number of studies have indicated that the ipsilesional arm may be impaired after stroke. There is, however, a lack of knowledge whether ipsilesional deficits influence movement performance during purposeful daily tasks. OBJECTIVE: The aim of this study was to investigate whether, and to what extent, movement impairments are present while performing an ipsilesional upper extremity task during the first 3 months after stroke. METHODS: Movement kinematics describing movement time, smoothness, velocity, strategy, and pattern were captured during a standardized drinking task in 40 persons with first-ever stroke and 20 controls...
January 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28092712/-global-bioethics-and-biocultural-ethics
#17
Ricardo Rozzi
The biocultural ethic recovers an understanding of the vital links between the life habits of the coinhabitants (humans and other-than-human) that share a habitat. The ″3Hs″ formal framework of the biocultural ethics provides a conceptual and methodological tool to understand and to better manage complex eco-social or biocultural systems in heterogeneous regions of the planet. From the global bioethics originally proposed by V.R. Potter, the integration of theory and praxis promoted by Alfredo Pradenas in the Bioethics Society of Chile, and the conceptual framework of biocultural ethics (including traditions of philosophical thought, scientific and Amerindians), I develop a comparative analysis of: 1...
September 2016: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/28074464/investigation-of-hand-function-among-children-diagnosed-with-autism-spectrum-disorder-with-upper-extremity-trauma-history
#18
Meral Huri, Sedef Şahin, Hülya Kayıhan
BACKGROUND: The present study was designed to compare hand function in autistic children with history of upper extremity trauma with that of autistic children those who do not have history of trauma. METHODS: The study group included total of 65 children diagnosed with autism spectrum disorder (ASD) and was divided into 2 groups: children with trauma history (Group I) and control group (Group II) (Group I: n=28; Group II: n=37). Hand function was evaluated with 9-Hole Peg Test and Jebsen Hand Function Test...
November 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28049217/-the-most-cited-articles-in-volume-41-of-psychiatrische-praxis-congratulations
#19
Philipp Reimann, Steffi G Riedel-Heller
No abstract text is available yet for this article.
January 2017: Psychiatrische Praxis
https://www.readbyqxmd.com/read/27965279/sex-differences-in-prodromal-symptoms-in-acute-coronary-syndrome-in-patients-aged-55%C3%A2-years-or-younger
#20
Nadia A Khan, Stella S Daskalopoulou, Igor Karp, Mark J Eisenberg, Roxanne Pelletier, Meytal Avgil Tsadok, Kaberi Dasgupta, Colleen M Norris, Louise Pilote
BACKGROUND: Studies suggest that young women are at highest risk for failing to recognise early symptoms of acute coronary syndrome (ACS). OBJECTIVES: To examine sex differences in prodromal symptoms occurring days and weeks prior to the acute presentation of ACS. We also examined health-seeking behaviours and prehospital management in young patients. METHODS: Prospective cross-sectional analysis of 1145 patients (368 women) hospitalised for ACS, aged ≤55 years, from the GENdEr and Sex DetermInantS of Cardiovascular Disease: From Bench to Beyond Premature Acute Coronary SYndrome cohort study (January 2009-April 2013)...
December 13, 2016: Heart: Official Journal of the British Cardiac Society
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