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https://www.readbyqxmd.com/read/29244005/ghost-global-hepatitis-outbreak-and-surveillance-technology
#1
Atkinson G Longmire, Seth Sims, Inna Rytsareva, David S Campo, Pavel Skums, Zoya Dimitrova, Sumathi Ramachandran, Magdalena Medrzycki, Hong Thai, Lilia Ganova-Raeva, Yulin Lin, Lili T Punkova, Amanda Sue, Massimo Mirabito, Silver Wang, Robin Tracy, Victor Bolet, Thom Sukalac, Chris Lynberg, Yury Khudyakov
BACKGROUND: Hepatitis C is a major public health problem in the United States and worldwide. Outbreaks of hepatitis C virus (HCV) infections associated with unsafe injection practices, drug diversion, and other exposures to blood are difficult to detect and investigate. Effective HCV outbreak investigation requires comprehensive surveillance and robust case investigation. We previously developed and validated a methodology for the rapid and cost-effective identification of HCV transmission clusters...
December 6, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29243787/atherosclerosis-and-cardiovascular-involvement-in-celiac-disease-the-role-of-autoimmunity-and-inflammation
#2
L Santoro, G De Matteis, M Fuorlo, B Giupponi, A M Martone, F Landi, R Landolfi, A Santoliquido
OBJECTIVE: The aim of this review is to explore the evidence about the association among celiac disease (CD), atherosclerosis (AS) and cardiovascular (CV) diseases, and the role of inflammation in this connection. MATERIALS AND METHODS: A systematic literature search was conducted using PubMed, EMBASE, and Cochrane Library for the association among CD, AS and CV diseases. RESULTS: Several studies reported the association of CD with accelerated AS, as evidenced by the alterations of a number of parameters indicative of subclinical AS, as increased carotid artery intima-media thickness, endothelial dysfunction and increased arterial stiffness...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29243679/surgery-related-factors-affecting-the-stability-of-orthodontic-mini-implants-screwed-in-alveolar-process-interdental-spaces-a-systematic-literature-review
#3
Greta Gintautaitė, Alė Gaidytė
The ambiguous results of scientific researches on surgical factors affecting the stability of mini implants (MI) impels the physicians to constantly analyze this problem. The objective of this article was to conduct a systematic literature review about surgery related factors affecting the stability of MI screwed in alveolar process buccal surface between the second premolar and first molar roots based on peer reviewed publications of 2009-2015. The Cochrane and PRISMA references were used while searching for scientific literature...
2017: Stomatologija
https://www.readbyqxmd.com/read/29243356/turning-frequency-in-adult-bedridden-patients-to-prevent-hospital-acquired-pressure-ulcer-a-scoping-review
#4
Chew H-S Jocelyn, Emelia Thiara, Violeta Lopez, Shefaly Shorey
The aim of this study was to identify current research on turning frequencies of adult bed-bound patients and inform future turning practices for hospitals based on evidence-based practice. We undertook a scoping review framework that provided a transparent and systematic methodology using 8 electronic databases (CINAHL, PubMed, Cochrane Library, ScienceDirect, PsycINFO, Scopus, ProQuest, and Web of Science) to identify articles published from 2000 to 2016. Articles were included if they focused on the prevention of hospital-acquired pressure ulcers related to the frequency of turning or repositioning of bed-bound patients...
December 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29241958/time-to-appendectomy-for-acute-appendicitis-a-systematic-review
#5
REVIEW
Danielle B Cameron, Regan Williams, Yimin Geng, Ankush Gosain, Meghan A Arnold, Yigit S Guner, Martin L Blakely, Cynthia D Downard, Adam B Goldin, Julia Grabowski, Dave R Lal, Roshni Dasgupta, Robert Baird, Robert L Gates, Julia Shelton, Tim Jancelewicz, Shawn J Rangel, Mary T Austin
OBJECTIVE: The goal of this systematic review by the American Pediatric Surgical Association Outcomes and Evidence-Based Practice Committee was to develop recommendations regarding time to appendectomy for acute appendicitis in children within the context of preventing adverse events, reducing cost, and optimizing patient/parent satisfaction. METHODS: The committee selected three questions that were addressed by searching MEDLINE, Embase, and the Cochrane Library databases for English language articles published between January 1, 1970 and November 3, 2016...
November 20, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29241013/libreta-computerized-optimization-and-code-synthesis-for-electron-repulsion-integral-evaluation
#6
Jun Zhang
A new library called LIBRETA for the evaluation of electron repulsion integrals (ERIs) and their first and second derivatives over segmented and contracted Gaussian functions is developed. Our LIBRETA is optimized from three aspects: (1) The Obara-Saika, Dupuis-Rys-King, and McMurchie-Davidson method are all employed. The recurrence relations involved are optimized by tree-search for each combination of angular momenta, and in the best case, 50% of the intermediates can be eliminated to reduce the computational cost...
December 14, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29237581/a-web-based-training-resource-for-therapists-to-deliver-an-evidence-based-exercise-program-for-rheumatoid-arthritis-of-the-hand-isarah-design-development-and-usability-testing
#7
Cynthia Swarnalatha Srikesavan, Esther Williamson, Lucy Eldridge, Peter Heine, Jo Adams, Tim Cranston, Sarah E Lamb
BACKGROUND: The Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH) is a tailored, progressive exercise program for people having difficulties with wrist and hand function due to rheumatoid arthritis (RA). The program was evaluated in a large-scale clinical trial and was found to improve hand function, was safe to deliver, and was cost-effective. These findings led to the SARAH program being recommended in the UK National Institute for Health and Care Excellence guidelines for the management of adults with RA...
December 13, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29236350/iccs-escca-consensus-guidelines-to-detect-gpi-deficient-cells-in-paroxysmal-nocturnal-hemoglobinuria-pnh-and-related-disorders-part-3-data-analysis-reporting-and-case-studies
#8
Andrea Illingworth, Iuri Marinov, D Robert Sutherland, Orianne Wagner Ballon, Luigi DelVecchio
Over the past several years, a diverse group of physicians and other laboratory scientists have developed various recommendations and guidelines regarding best practices for PNH testing. This manuscript is based on these previous recommendations as well as various other relevant publications of experts in the area of PNH testing. The goal is to provide flow cytometry laboratories with an updated consensus approach to analysis and reporting of PNH results and to address the most common analytical challenges for accurate reporting of this rare disease...
December 13, 2017: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/29232988/does-antibiotic-treatment-duration-affect-the-outcomes-of-exacerbations-of-asthma-and-copd-a-systematic-review
#9
Marie Stolbrink, Jack Amiry, John D Blakey
Asthma and chronic obstructive pulmonary disease (COPD) cause significant morbidity and mortality worldwide, primarily through exacerbations. Exacerbations are often treated with antibiotics but their optimal course duration is uncertain. Reducing antibiotic duration may influence antimicrobial resistance but risks treatment failure. The objective of this article is to review published literature to investigate whether shorter antibiotic therapy duration affects clinical outcomes in the treatment of asthma and COPD exacerbations...
January 1, 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29227873/restraint-use-in-older-adults-in-home-care-a-systematic-review
#10
REVIEW
Kristien Scheepmans, Bernadette Dierckx de Casterlé, Louis Paquay, Koen Milisen
OBJECTIVES: To get insight into restraint use in older adults receiving home care and, more specifically, into the definition, prevalence and types of restraint, as well as the reasons for restraint use and the people involved in the decision-making process. DESIGN: Systematic review. DATA SOURCES: Four databases (i.e. Pubmed, CINAHL, Embase, Cochrane Library) were systematically searched from inception to end of April 2017. REVIEW METHODS: The study encompassed qualitative and quantitative research on restraint use in older adults receiving home care that reported definitions of restraint, prevalence of use, types of restraint, reasons for use or the people involved...
November 23, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29225283/gene-cloning-and-expression-of-fungal-lignocellulolytic-enzymes-from-the-rumen-of-gayal-bos-frontalis
#11
Jing Leng, Xuchuan Liu, Chunyong Zhang, Renjun Zhu, Huaming Mao
A total of 6,219 positive clones were obtained by constructing a BAC library of uncultured ruminal fungi of gayal, and two clones (xynF1 and eglF2) with lignocellulolytic enzyme activity were selected. The sequencing results showed that xynF1 and eglF2 had 903-bp, and 1,995-bp, open reading frames likely to encode β-xylanase (XynF1) and β-glucosidase (EglF2), respectively. The amino acid sequence of XynF1 had 99% coverage and 95% homology to the endo-β-1,4-xylanase encoded by the cellulase gene of Orpinomyces sp...
December 8, 2017: Journal of General and Applied Microbiology
https://www.readbyqxmd.com/read/29225141/effects-of-healthcare-professional-delivered-early-feeding-interventions-on-feeding-practices-and-dietary-intake-a-systematic-review
#12
REVIEW
Karen Matvienko-Sikar, Elaine Toomey, Lisa Delaney, Janas Harrington, Molly Byrne, Patricia M Kearney
BACKGROUND: Childhood obesity is a global public health challenge. Parental feeding practices, such as responsive feeding, are implicated in the etiology of childhood obesity. PURPOSE: This systematic review aimed to examine of effects of healthcare professional-delivered early feeding interventions, on parental feeding practices, dietary intake, and weight outcomes for children up to 2 years. The role of responsive feeding interventions was also specifically examined...
December 7, 2017: Appetite
https://www.readbyqxmd.com/read/29220742/meta-analyses-of-newer-antiepileptic-drugs-as-adjunct-for-treatment-of-focal-epilepsy-in-children
#13
Nurul-Ain Mohd-Tahir, Shu-Chuen Li
AIM: This study conducted a systematic review evaluating the effectiveness of newer antiepileptic drugs (AEDs) (namely, lamotrigine, levetiracetam, topiramate, vigabatrin, zonisamide, oxcarbazepine, perampanel, gabapentin, and stiripentol) as add-on for treatment of focal epilepsy in children. METHODS: Articles were retrieved from EMBASE, Medline and Cochrane Library from inception to January 2016. Treatment outcomes were analysed based on responder, seizure-free, withdrawal and adverse event rates...
November 22, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29219906/targeted-interventions-to-advance-a-culture-of-inquiry-at-a-large-multicampus-hospital-among-nurses
#14
Eileen J Carter, Reynaldo R Rivera, Kelly A Gallagher, Kenrick D Cato
OBJECTIVES: The aim of this study is to assist nurse leaders in developing innovative structures to foster a culture of inquiry among professional nurses. BACKGROUND: Critical to nurse's engagement in evidence-based practice (EBP) is a culture of inquiry, in which nurses critically evaluate patient care activities and actively review existing evidence to address identified clinical issues. A bundle of structural interventions was implemented across a large, multisite hospital to advance a culture of inquiry...
January 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29217324/-medical-human-resources-planning-in-europe-a-literature-review-of-the-forecasting-models
#15
N Benahmed, D Deliège, A De Wever, M Pirson
BACKGROUND: Healthcare is a labor-intensive sector in which half of the expenses are dedicated to human resources. Therefore, policy makers, at national and internal levels, attend to the number of practicing professionals and the skill mix. This paper aims to analyze the European forecasting model for supply and demand of physicians. METHODS: To describe the forecasting tools used for physician planning in Europe, a grey literature search was done in the OECD, WHO, and European Union libraries...
December 4, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29217122/phase-i-iii-development-of-the-eortc-qlq-anl27-a-health-related-quality-of-life-questionnaire-for-anal-cancer
#16
Samantha C Sodergren, Colin D Johnson, Alexandra Gilbert, Krzysztof A Tomaszewski, William Chu, Hans T Chung, Kristopher Dennis, Isacco Desideri, Robert Glynne-Jones, Marianne Grønlie Guren, Dimitrios Kardamakis, Karen Nugent, Heike Schmidt, David Sebag-Montefiore, Vassilios Vassiliou
BACKGROUND AND PURPOSE: There is currently no health-related quality of life (HRQoL) measure specific to anal cancer. Our objective was to develop an anal cancer HRQoL module to supplement the EORTC QLQ-C30 questionnaire using EORTC Quality of Life Group Guidelines. MATERIALS AND METHOD: In order to generate a list of HRQoL issues facing anal cancer patients treated with chemoradiotherapy (CRT), we systematically reviewed the literature and conducted semi-structured interviews with patients and health care professionals (HCPs)...
December 4, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29208800/spanning-the-horizon-of-accuracy-of-different-intraoral-radiographic-modalities-a-systematic-review
#17
Mohnish Muchhal, Lav K Niraj, Devanshu Chaudhary, Irfan Ali, Kuldeep Dhama, Basavaraj Patthi
AIM: This study was conducted with an aim to systematically review the literature for assessing the accuracy of intraoral radiographs in detection of dental caries. INTRODUCTION: Despite the advancements in oral disease science, dental caries continues to be a worldwide health concern, affecting humans of all ages. Correct diagnosis of caries is critical both in clinical practice as well as in epidemiology and radiography are worthwhile adjunct for a thorough examination...
December 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29208766/mir-146a-c-g-polymorphism-increased-the-risk-of-head-and-neck-cancer-but-overall-cancer-risk-a-analyses-of-89-studies
#18
Dezhong Sun, Xiaoyan Zhang, Xiaolei Zhang
Several studies have evaluated the association of miR-146a C/G with head and neck cancer (HNC) susceptibility, and overall cancer risk, but inconclusive outcomes. To drive a more precise estimation, we carried out this meta-analysis. The literature searched from Medline (Mainly PubMed), Embase, the Cochrane Library and Google Scholar databases to identify eligible studies. A total of 89 studies were included. The results showed that miR-146a C/G was significantly associated with increased head and neck cancer risk in dominant model ( I2 = 15...
December 5, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/29208190/preventing-blood-borne-virus-infection-in-people-who-inject-drugs-in-the-uk-systematic-review-stakeholder-interviews-psychosocial-intervention-development-and-feasibility-randomised-controlled-trial
#19
Gail Gilchrist, Davina Swan, April Shaw, Ada Keding, Sarah Towers, Noel Craine, Alison Munro, Elizabeth Hughes, Steve Parrott, Noreen Mdege, John Strang, Avril Taylor, Judith Watson
BACKGROUND: Opioid substitution therapy and needle exchanges have reduced blood-borne viruses (BBVs) among people who inject drugs (PWID). Some PWID continue to share injecting equipment. OBJECTIVES: To develop an evidence-based psychosocial intervention to reduce BBV risk behaviours and increase transmission knowledge among PWID, and conduct a feasibility trial among PWID comparing the intervention with a control. DESIGN: A pragmatic, two-armed randomised controlled, open feasibility trial...
November 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29207529/improving-the-catalytic-property-of-the-glycoside-hydrolase-lxyl-p1-2-by-directed-evolution
#20
Jing-Jing Chen, Xiao Liang, Hui-Xian Li, Tian-Jiao Chen, Ping Zhu
The glycoside hydrolase LXYL-P1-2 from Lentinula edodes can specifically hydrolyze 7-β-xylosyltaxanes to form 7-β-hydroxyltaxanes for the semi-synthesis of paclitaxel. In order to improve the catalytic properties of the enzyme, we performed error-prone PCR to construct the random mutant library of LXYL-P1-2 and used the methanol-induced plate method to screen the mutants with improved catalytic properties. Two variants, LXYL-P1-2-EP1 (EP1, S91D mutation) and LXYL-P1-2-EP2 (EP2, T368E mutation), were obtained from the library and exhibited 17% and 47% increases in their catalytic efficiencies on 7-β-xylosyl-10-deacetyltaxol...
December 4, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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