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https://www.readbyqxmd.com/read/29451507/-appropriateness-in-cardiology-a-statement-of-the-anmco-veneto-region
#1
Guerrino Zuin, Gianfranco Frigo, Loris Roncon, Aldo Bonso, Emanuele Carbonieri, Fabio Chirillo, Fabio De Conti, Pietro Delise, Alessandro Desideri, Daniele D'Este, Loredano Milani, Roberto Valle, Claudio Bilato
Inappropriate tests are responsible for longer waiting lists, higher economical costs for the National Health System and major clinical risks due to radiation exposure from prescription abuse of diagnostic testing. Clinical inappropriateness frequently derives from poor knowledge of guidelines, "defensive medicine" approach and/or repeat requests of patients and family members. About one third of non-invasive imaging tests are considered inappropriate.In order to define the most appropriate instruments for the follow-up of the most common cardiovascular diseases with the highest risk of inappropriateness, all the cardiologists of the Veneto Region (Italy), along with the local chapters of the main national cardiology societies and general practitioners have been involved by the Regional Section of the Italian Association of Hospital Cardiologists (ANMCO) in several scientific meetings on the following topics: hypertension, chronic ischemic heart disease, valvular heart disease, heart failure, and atrial fibrillation...
January 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29450741/utility-of-cardiac-computed-tomography-scanning-in-the-diagnosis-and-pre-operative-evaluation-of-patients-with-infective-endocarditis
#2
Jason R Sims, Nandan S Anavekar, Krishnaswamy Chandrasekaran, James M Steckelberg, Walter R Wilson, Bernard J Gersh, Larry M Baddour, Daniel C DeSimone
Transesophageal echocardiography (TEE) is the gold standard imaging study used in the diagnosis of infective endocarditis (IE). Computed tomography angiography (CTA) has undergone rapid advancement as a cardiac imaging technique and has previously shown promise in small non-randomized studies for evaluation of IE. We hypothesized that cardiac CTA would perform similarly to TEE in the detection of endocarditic lesions and that there would be no difference in clinical outcomes whether the coronary arteries were evaluated by CTA or invasive coronary angiography (ICA)...
February 15, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29447720/no-257-ultrasonographic-cervical-length-assessment-in-predicting-preterm-birth-in-singleton-pregnancies
#3
Kenneth Lim, Kimberly Butt, Joan M Crane
OBJECTIVES: To review (1) the use of ultrasonographic-derived cervical length measurement in predicting preterm birth and (2) interventions associated with a short cervical length. OUTCOMES: Reduction in rates of prematurity and/or better identification of those at risk, as well as possible prevention of unnecessary interventions. EVIDENCE: Published literature was retrieved through searches of PubMed and The Cochrane Library up to December 2009, using appropriate controlled vocabulary and key words (preterm labour, ultrasound, cervix, incompetent cervix, transvaginal, transperineal, cervical length, fibronectin)...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447330/is-central-lung-tumour-location-really-predictive-for-occult-mediastinal-nodal-disease-in-suspected-non-small-cell-lung-cancer-staged-cn0-on-18f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#4
Herbert Decaluwé, Johnny Moons, Steffen Fieuws, Walter De Wever, Christophe Deroose, Alessia Stanzi, Lieven Depypere, Kristiaan Nackaerts, Johan Coolen, Maarten Lambrecht, Eric Verbeken, Dirk De Ruysscher, Johan Vansteenkiste, Dirk Van Raemdonck, Paul De Leyn, Christophe Dooms
OBJECTIVES: Current guidelines recommend preoperative invasive mediastinal staging in centrally located tumours with negative mediastinum on positron emission tomography-computed tomography, based on a 20-30% prevalence of occult mediastinal disease (pN2-3). However, a uniform definition of central tumour location is lacking. Our objective was to determine the best definition in predicting occult pN2-3. METHODS: A single-institution database was queried for patients with (suspected) non-small-cell lung cancer staged cN0 after positron emission tomography-computed tomography and referred to invasive staging and/or primary surgery...
February 13, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29446832/an-assessment-of-18-f-fdg-pet-ct-for-thoracic-screening-and-risk-stratification-of-pulmonary-nodules-in-multiple-endocrine-neoplasia-type-1
#5
Alvin So, Owen Pointon, Richard Hodgson, John Burgess
CONTEXT: Bronchopulmonary neuroendocrine tumours (bpNETs) and thymic carcinoid (ThC) are features of Multiple Endocrine Neoplasia Type 1 (MEN 1) and surveillance guidelines recommend periodic thoracic imaging. The optimal thoracic imaging modality and screening frequency remains uncertain as does the prognosis of small lung nodules when identified. OBJECTIVES: To evaluate fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) for identification and prognostic assessment of thoracic lesions in MEN 1...
February 15, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29446669/segmental-arterial-mediolysis-abdominal-imaging-of-and-disease-course-in-111-patients
#6
Sailen G Naidu, Christine O Menias, Rahmi Oklu, Robert S Hines, Kinan Alhalabi, Gerges Makar, Fadi E Shamoun, Stanislav Henkin, Robert D McBane
OBJECTIVE: The purpose of this study is to identify the imaging characteristics of segmental arterial mediolysis (SAM) at presentation and establish the longitudinal course of disease. MATERIALS AND METHODS: We retrospectively identified patients with SAM at a single institution from 2000 through 2015. Diagnosis was based on published guidelines with multidisciplinary consensus. Imaging studies obtained at initial evaluation were reviewed to evaluate imaging findings and vascular territory distribution...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29445426/the-effect-of-different-methods-and-image-analyzers-on-the-results-of-the-in-vivo-comet-assay
#7
Takahiro Kyoya, Rika Iwamoto, Yuko Shimanura, Megumi Terada, Shuichi Masuda
Introduction: The in vivo comet assay is a widely used genotoxicity test that can detect DNA damage in a range of organs. It is included in the Organisation for Economic Co-operation and Development Guidelines for the Testing of Chemicals. However, various protocols are still used for this assay, and several different image analyzers are used routinely to evaluate the results. Here, we verified a protocol that largely contributes to the equivalence of results, and we assessed the effect on the results when slides made from the same sample were analyzed using two different image analyzers (Comet Assay IV vs Comet Analyzer)...
2018: Genes and Environment: the Official Journal of the Japanese Environmental Mutagen Society
https://www.readbyqxmd.com/read/29444467/olfactory-function-in-systemic-lupus-erythematosus-and-systemic-sclerosis-a-longitudinal-study-and-review-of-the-literature
#8
REVIEW
Mariana Freschi Bombini, Fernando Augusto Peres, Aline Tamires Lapa, Nailú Angélica Sinicato, Beatriz Ricato Quental, Ágatha de Souza Melo Pincelli, Tiago Nardi Amaral, Caroline Cristina Gomes, Ana Paula Del Rio, João Francisco Marques-Neto, Lilian T L Costallat, Paula Teixeira Fernandes, Fernando Cendes, Leticia Rittner, Simone Appenzeller
BACKGROUND/PURPOSE: To evaluate olfactory function in systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and healthy controls over a 2-year period, and to determine the association of olfactory dysfunction with age, disease activity, disease damage, treatment, anxiety and depression symptoms and limbic structures volumes. METHODS: Consecutive SLE and SSc patients were enrolled in this study. Clinical, laboratory disease activity and damage were assessed according to diseases specific guidelines...
February 11, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29439672/renal-manifestations-of-tuberous-sclerosis-complex-patients-and-parents-knowledge-and-routines-for-renal-follow-up-a-questionnaire-study
#9
I Cockerell, M Guenin, K Heimdal, M Bjørnvold, K K Selmer, O Rouvière
BACKGROUND: Renal angiomyolipomas (AMLs) are a major clinical feature in patients with tuberous sclerosis complex (TSC). Spontaneous bleeding can be life threatening, and appropriate information and proper surveillance and management are important to limit morbidity and mortality. Because TSC is a rare disease, patients are at risk of suboptimal medical management. Our aim was to investigate patients' and parents' knowledge about renal angiomyolipomas (AMLs) in Tuberous Sclerosis Complex (TSC) and to identify current routines for renal follow-up...
February 13, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29438217/suppressed-thyroglobulin-performs-better-than-stimulated-thyroglobulin-in-defining-an-excellent-response-in-patients-with-differentiated-thyroid-cancer
#10
Hou-Yang Hu, Jun Liang, Teng Zhang, Teng Zhao, Yan-Song Lin
PURPOSE: According to the American Thyroid Association guidelines in 2015, both an unstimulated thyroglobulin (u-Tg) below 0.2 ng/ml and a stimulated thyroglobulin (s-Tg) below 1.0 ng/ml were required along with negative imaging findings to define an excellent response. This study aimed to investigate whether a u-Tg below 0.2 ng/ml coincides with a s-Tg below 1 ng/ml. PATIENTS AND METHODS: A total of 290 patients with nonmetastatic differentiated thyroid cancer were retrospectively evaluated with a median follow-up of 36 months...
March 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29436995/bacterial-luciferase-gene-cassette-as-a-real-time-bioreporter-for-infection-model-and-drug-evaluation
#11
Xiwen Wang, Hang Chi, Bo Zhou, Wenliang Li, Zhiping Li, Zhiping Xia
The bacterial luciferase gene cassette (lux) is an ideal bioreporter for real-time monitoring of the dynamics of bacteria because it is a fully autonomous, substrate-free bioluminescent reporter system available in a prokaryotic or eukaryotic host background. The lux operon is emerging as a powerful bioreporter for the study of a wide range of biological processes such as gene function, drug discovery and development, cellular trafficking, protein-protein interactions, and especially tumorigenesis and cancer treatment...
February 13, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29436443/diagnosis-and-management-of-cerebral-venous-thrombosis
#12
Roya Behrouzi, Martin Punter
Cerebral venous thrombosis (CVT) is rare and accounts for 0.5% of all strokes. Its clinical presentation is variable and diagnosis requires a high index of clinical suspicion in conjunction with neuroradiological diagnostic support. Treatment options are limited and are mostly based on consensus. Therefore, familiarity with international guidelines is important. Outcome is often good and most patients make a full recovery, although a small proportion suffers death or disability. Here, we describe the clinical features, risk factors, acute imaging features, management and complications of CVT...
February 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29435208/reasonable-outcome-of-avulsed-permanent-upper-incisor-after-seven-years-follow-up-period-a-case-report
#13
Egle Bendoraitiene, Sandra Zemgulyte, Marija Borisovaite
Background: Avulsion of the permanent teeth is one of the most serious oral health problems among active children and adolescents. Traumatized patients require immediate and correct treatment in order to restore damaged structures and function that have major impact on daily patient's life. As a result, proper guidelines and fast treatment methods are necessary. This case report discusses treatment of maxillary right central incisor with an open apex that had been avulsed and replanted...
October 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29433347/neuroimaging-utilization-and-findings-in-headache-outpatients-significance-of-red-and-yellow-flags
#14
Nathan P Young, Muhamad Y Elrashidi, Paul M McKie, Jon O Ebbert
Background Neuroimaging for headache commonly exceeds published guideline recommendations and may be overutilized. Methods We conducted a retrospective cross-sectional study of all outpatient community patients at Mayo Clinic Rochester who underwent a neuroimaging study for a headache indication in 2015. We assessed the neuroimaging utilization pattern, clinical application of red flags, and concordance with neuroimaging guidelines. Results We identified 190 outpatients who underwent 304 neuroimaging studies for headache...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29431526/the-potential-role-of-statins-in-treating-liver-disease
#15
Konstantinos P Imprialos, Konstantinos Stavropoulos, Michael Doumas, Anastasia Skalkou, Ioanna Zografou, Vasilios G Athyros
Statins are commonly use for the management of dyslipidemia, worldwide. Various studies have demonstrated that statins offer significant reduction in the risk of cardiovascular morbidity and mortality. However, this class of drugs has been implicated in potential liver toxicity, thus has been considered as a "forbidden-drug" in patients with increased liver enzymes. Areas covered: Studies have shown that statins might offer clinical benefits in the setting of viral hepatitis, progression of cirrhosis, and hepatocellular carcinoma...
February 12, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29429557/prevalence-of-incidental-clinically-relevant-pancreatic-cysts-at-diagnosis-based-on-current-guidelines
#16
Jose Manuel Mella, Estanislao Jesús Gómez, Mariana Omodeo, Matias Manzotti, Mariela Roel, Lisandro Pereyra, Carolina Fischer, Nicolás Panigadi, Raquel González, Pablo Luna, Silvia Cecilia Pedreira, Daniel Gustavo Cimmino, Luis Alberto Boerr
BACKGROUND: Most pancreatic cysts (PCs) found incidentally by CT and MRI scans might not be clinically important according to the Fukuoka guidelines, the American Gastroenterological Association (AGA) guidelines and European guidelines. AIMS: To determine and compare the prevalence of incidental clinically important PCs (CIPCs). METHODS: Abdominal contrast-enhanced CT or MRI scans performed during a one-year period were retrospectively reviewed to identify incidental PCs...
February 8, 2018: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/29427992/apple-condom-and-cocaine-body-stuffing-in-prison-a-case-report
#17
Benedicte Jalbert, Nguyen Toan Tran, Stephan von Düring, Pierre-Alexandre Poletti, Ian Fournier, Catherine Hafner, Celestine Dubost, Laurent Gétaz, Hans Wolff
BACKGROUND: Drug dealers and drug users resort to body stuffing to hastily conceal illicit drugs by ingesting their drug packets. This practice represents a medical challenge because rupture of the often insecure packaging can be toxic and even lethal. In an emergency setting, official guidelines are needed to help the medical team decide on the proper treatment. A preliminary observation period is generally accepted but its duration varies from hours to eventual packet expulsion. CASE PRESENTATION: This case involves a 20-year-old white man in detention who claimed to have ingested one cocaine packet wrapped in plastic food-wrap and a condom in anticipation of an impending cell search...
February 11, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29427704/finding-makhubu-a-morphological-forensic-facial-comparison
#18
T M R Houlton, M Steyn
June 16, 1976, marks the Soweto Youth Student Uprising in South Africa. A harrowing image capturing police brutality from that day comprises of 18-year-old Mbuyisa Makhubu carrying a dying 12-year-old Hector Peterson. This circulated international press and contributed to world pressure against the apartheid government. This elevated Makhubu's profile with the national security police and forced him to flee to Botswana, then Nigeria, before disappearing in 1978. In 1988, Victor Vinnetou illegally entered Canada and was later arrested on immigration charges in 2004...
February 4, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29426675/the-use-of-cerebral-imaging-for-investigating-delirium-aetiology
#19
Zina Hijazi, Peter Lange, Rosie Watson, Andrea B Maier
BACKGROUND: This study aims to investigate the frequency and patterns of use of cerebral imaging in delirium and to describe pathological changes associated with delirium using computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: This retrospective observational study included patients with delirium admitted to a tertiary hospital (The Royal Melbourne Hospital, Australia) between January 2015 and August 2016. Data on cerebral imaging was collected and positive imaging findings were defined as: Acute or subacute infarct, haemorrhage, abscess, neoplasm, vasculitis, posterior reversible encephalopathy syndrome, encephalitis, acute demyelination, or fat embolism...
February 6, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29425931/surveillance-imaging-and-alpha-fetoprotein-for-early-detection-of-hepatocellular-carcinoma-in-patients-with-cirrhosis-a-meta-analysis
#20
Kristina Tzartzeva, Joseph Obi, Nicole E Rich, Neehar D Parikh, Jorge A Marrero, Adam Yopp, Akbar Waljee, Amit G Singal
BACKGROUND & AIMS: Society guidelines differ in their recommendations for surveillance to detect early-stage hepatocellular carcinoma (HCC) in patients with cirrhosis. We compared the performance of surveillance imaging, with or without alpha fetoprotein (AFP), for early detection of HCC in patients with cirrhosis METHODS: Two reviewers searched MEDLINE and SCOPUS from January 1990 through August 2016 to identify published sensitivity and specificity of surveillance strategies for overall and early detection of HCC...
February 6, 2018: Gastroenterology
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