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https://www.readbyqxmd.com/read/29679839/xenon-detection-in-human-blood-analytical-validation-by-accuracy-profile-and-identification-of-critical-storage-parameters
#1
Cécile Frampas, Julia Ney, Mark Coburn, Marc Augsburger, Vincent Varlet
Xenon is a rare, mostly inert, noble gas that has applications in a wide range of fields, including medicine. Xenon acts on the human body as a useful organ-protective and anesthetic agent and has also been previously studied for potential applications in fields such as optics, aerospace and medical imaging. Recently, it was discovered that xenon can boost erythropoietin production, and it has been used as a performance-enhancing agent in international sports competitions such as the Sochi Olympic Games. Therefore, screening methods to detect the misuse of xenon by analysis of biological samples and to monitor anesthesia kinetics and efficiency are being investigated...
April 13, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29679728/magnetic-resonance-imaging-of-the-lumbar-spine-determining-clinical-impact-and-potential-harm-from-overuse
#2
Nathan M Wnuk, Tarik K Alkasab, Daniel I Rosenthal
BACKGROUND: Lumbar spine MRI is frequently said to be "overused" in the evaluation of low-back pain, yet data concerning the extent of overuse and on potential harmful effects are lacking. PURPOSE: To determine the proportion of examinations with a detectable impact on patient care (actionable outcomes). STUDY DESIGN: Retrospective cohort study PATIENT SAMPLE: 5,365 outpatient lumbar spine MR examinations OUTCOME MEASURES: Actionable outcomes included: 1) findings leading to an intervention making use of anatomical information such as surgery; 2) new diagnoses of cancer, infection, or fracture; or 3) following known lumbar spine pathology...
April 18, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29679214/improvement-of-radiology-reporting-in-a-clinical-cancer-network-impact-of-an-optimised-multidisciplinary-workflow
#3
A W Olthof, J Borstlap, W W Roeloffzen, P M C Callenbach, P M A van Ooijen
PURPOSE: To assess the effectiveness of implementing a quality improvement project in a clinical cancer network directed at the response assessment of oncology patients according to RECIST-criteria. METHODS: Requests and reports of computed tomography (CT) studies from before (n = 103) and after (n = 112) implementation of interventions were compared. The interventions consisted of: a multidisciplinary working agreement with a clearly described workflow; subspecialisation of radiologists; adaptation of the Picture Archiving and Communication System (PACS); structured reporting...
April 20, 2018: European Radiology
https://www.readbyqxmd.com/read/29677464/improving-the-quality-of-preclinical-research-echocardiography-observations-training-and-guidelines-for-measurement
#4
Daniel G Donner, Helen Kiriazis, Xiao-Jun Du, Thomas H Marwick, Julie R McMullen
Informal training in preclinical research may be a contributor to the poor reproducibility of preclinical cardiology research and low rates of translation into clinical research and practice. Mouse echocardiography is a widely used technique to assess cardiac structure and function in drug intervention studies using disease models. The inter-observer variability (IOV) of clinical echocardiographic measurements has been shown to improve with formalized training, but preclinical echocardiography lacks similarly critical standardization of training...
April 20, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29676860/diagnostic-performance-of-diffusion-weighted-imaging-for-differentiating-benign-and-malignant-gallbladder-lesions-a-systematic-review-and-meta-analysis
#5
Myung-Won You, Seong Jong Yun
BACKGROUND: Although diffusion-weighted imaging (DWI) has been characterized as an alternative imaging modality for gallbladder (GB) lesions, it has not been routinely used in clinical practice because of relatively low signal-to-noise ratio. PURPOSE: To assess the sensitivity and specificity of the diagnostic performance of DWI for differentiating benign and malignant GB lesions. STUDY TYPE: Meta-analysis. POPULATION: Patients with GB lesions...
April 20, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29676717/-supervising-quality-of-care-through-the-patients-eyes-a-different-approach-to-inspection-is-required
#6
R J R Bouwmans, P B M Robben, R D Friele
The Netherlands Health and Youth Care Inspectorate (IGJ) wants to take the patient's perspective into account more often in its supervision of quality of care. The inspectorate already has some insight into this perspective via patients' reports; patients report complaints with the aim of preventing recurrence of the problem. However, the inspectorate does not further investigate the vast majority of these complaints and, furthermore, complaints with a clinical aspect are investigated far more often than organisational or communicational problems...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29675745/a-proposal-for-an-atypical-femur-fracture-treatment-and-prevention-clinical-practice-guideline
#7
REVIEW
R Dell, D Greene
The prevention as well as the treatment of atypical femur fractures (AFFs) remains controversial but there have been many clinical recommendations suggested. We have summarized these recommendations as well as expanded upon them in this paper. INTRODUCTION: The purpose of the paper was to develop a clinical practice guideline that both treats AFF and decreases the risk of AFF in patients requiring antiresorptive medications. Examples of these medications include bisphosphonates and denosumab for the treatment of osteoporosis...
April 19, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29675642/dutch-guideline-for-clinical-foetal-neonatal-and-paediatric-post-mortem-radiology-including-a-review-of-literature
#8
REVIEW
L J P Sonnemans, M E M Vester, E E M Kolsteren, J J H M Erwich, P G J Nikkels, P A M Kint, R R van Rijn, W M Klein
Clinical post-mortem radiology is a relatively new field of expertise and not common practice in most hospitals yet. With the declining numbers of autopsies and increasing demand for quality control of clinical care, post-mortem radiology can offer a solution, or at least be complementary. A working group consisting of radiologists, pathologists and other clinical medical specialists reviewed and evaluated the literature on the diagnostic value of post-mortem conventional radiography (CR), ultrasonography, computed tomography (PMCT), magnetic resonance imaging (PMMRI), and minimally invasive autopsy (MIA)...
April 19, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29675423/differences-of-the-morphology-of-subaxial-cervical-spine-endplates-between-chinese-and-white-men-and-women
#9
Qi Yao, Peng Yin, Kamran Khan, Tsung-Yuan Tsai, Jing-Sheng Li, Yong Hai, Peifu Tang, Guoan Li
Objective. The aim of this comparative anatomical study was to specifically investigate endplate morphology differences between Chinese and White men and women. Materials and Methods. Three-dimensional cervical endplate models were constructed using computed tomography imaging of 41 healthy Chinese and 24 White subjects. The morphologic measurements of cervical endplate included linear parameters (EPWu: upper endplate width; EPDu: upper endplate depth; EPWl: lower endplate width; and EPDl: lower endplate depth) and area parameters with a digital measuring system...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29672895/intrasheath-instability-of-the-peroneal-tendons-dynamic-ultrasound-imaging
#10
REVIEW
Ferdinando Draghi, Chandra Bortolotto, Anna Guja Draghi, Salvatore Gitto
Peroneal intrasheath instability is a painful snapping condition of the lateral ankle. It consists of a transient retromalleolar subluxation of the peroneal tendons without disruption of the superior peroneal retinaculum or evidence of a previous definite trauma. In type A intrasheath instability, the peroneus longus and brevis tendons are intact, and there is an intertendinous intrasheath switch. In type B intrasheath instability, the peroneus brevis tendon has a longitudinal split tear through which the peroneus longus subluxates...
April 19, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29672883/assessment-of-advanced-liver-fibrosis-and-the-risk-for-hepatic-decompensation-in-patients-with-congestive-hepatopathy
#11
REVIEW
Alexander Lemmer, Lisa B Van-Wagner, Daniel Ganger
Congestive hepatopathy (CH) arises from chronically elevated right sided heart pressures transmitted to the liver by passive venous congestion. Over time CH can lead to hepatic bridging fibrosis, decompensated cirrhosis, and hepatocellular carcinoma. Currently there are no evidence-based guidelines to direct appropriate screening or management of patients with CH partly because of the inability of current clinical tools (serum tests, imaging studies, liver stiffness measurements, and liver biopsy) to accurately estimate hepatic fibrosis or the risk for hepatic decompensation...
April 19, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29672022/the-roles-of-morphology-on-the-relaxation-rates-of-magnetic-nanoparticles
#12
Lijiao Yang, Zhenyu Wang, Lengceng Ma, Ao Li, Jingyu Xin, Ruixue Wei, Hongyu Lin, Ruifang Wang, Zhong Chen, Jinhao Gao
The shape of magnetic nanoparticles is of great importance in determining their contrast abilities for magnetic resonance imaging. Various magnetic nanoparticles have been developed to achieve high T1 or T2 relaxivities, but the mechanism on how morphology influences the water proton relaxation process is still unrevealed. Herein we synthesize manganese-doped iron oxide (MnIO) nanoparticles of the same volume with six different shapes and reveal the relationship between morphologies and T1/T2 relaxation rates...
April 19, 2018: ACS Nano
https://www.readbyqxmd.com/read/29671688/a-guide-to-identification-and-selection-of-axial-planes-in-magnetic-resonance-imaging-of-the-brain
#13
Shoichiro Otake, Toshiaki Taoka, Masayuki Maeda, William Tc Yuh
For brain magnetic resonance (MR) examination, three-dimensional imaging is commonly performed. Radiologists need to know the appropriate imaging angle for viewing. We present six imaging angles for the axial images. Each angle is determined by the reference line. The landmarks on the midsagittal MR image to determine the angle of the reference lines are as follows: the supraorbito-meatal line (the center of the mammillary body and the fastigium of the fourth ventricle), the orbito-meatal (OM) line (the center of the mammillary body and the most posterior point of the cerebellar tentorium), the Talairach anterior commissure (AC)-posterior commissure (PC) line (the superior edge of the AC and the inferior edge of the PC), the Schaltenbrand AC-PC line (the center of the AC and the center of the PC), the subcallosal line (the inferior border of the genu and the inferior border of the splenium of the corpus callosum), Reid's baseline (the center of the pituitary gland and the most posterior point of the cerebellar tentorium) and the brainstem vertical line (the line perpendicular to the posterior border of the brainstem)...
January 1, 2018: Neuroradiology Journal
https://www.readbyqxmd.com/read/29670029/concepts-in-light-microscopy-of-viruses
#14
REVIEW
Robert Witte, Vardan Andriasyan, Fanny Georgi, Artur Yakimovich, Urs F Greber
Viruses threaten humans, livestock, and plants, and are difficult to combat. Imaging of viruses by light microscopy is key to uncover the nature of known and emerging viruses in the quest for finding new ways to treat viral disease and deepening the understanding of virus–host interactions. Here, we provide an overview of recent technology for imaging cells and viruses by light microscopy, in particular fluorescence microscopy in static and live-cell modes. The review lays out guidelines for how novel fluorescent chemical probes and proteins can be used in light microscopy to illuminate cells, and how they can be used to study virus infections...
April 18, 2018: Viruses
https://www.readbyqxmd.com/read/29668929/chromoendoscopy-for-dysplasia-surveillance-in-inflammatory-bowel-disease
#15
Ann D Flynn, John F Valentine
Long-standing ulcerative colitis (UC) and extensive Crohn's colitis confer increased risk for development of colorectal cancer. Screening and surveillance colonoscopy programs aim to identify, resect, or detect dysplasia or colorectal cancer. Dysplastic lesions can be removed by endoscopic resection and patients with unresectable lesions can be referred for colectomy at an earlier stage, with the goal of reducing overall morbidity and mortality from colorectal cancer. Surveillance colonoscopy for patients with inflammatory bowel disease (IBD) is endorsed by multiple specialty societies...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668650/impact-of-an-advanced-imaging-utilization-review-program-on-downstream-health-care-utilization-and-costs-for-low-back-pain
#16
Janessa M Graves, Deborah Fulton-Kehoe, Jeffrey G Jarvik, Gary M Franklin
BACKGROUND: Early magnetic resonance imaging (MRI) for acute low back pain (LBP) has been associated with increased costs, greater health care utilization, and longer disability duration in workers' compensation claimants. OBJECTIVES: To assess the impact of a state policy implemented in June 2010 that required prospective utilization review (UR) for early MRI among workers' compensation claimants with LBP. RESEARCH DESIGN: Interrupted time series...
April 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29665588/current-technique-and-application-of-percutaneous-cryotherapy
#17
Andreas H Mahnken, Alexander Marc König, Jens Holger Figiel
PURPOSE:  Local ablative therapies have become an established treatment option in interventional oncology. Radiofrequency ablation (RFA) and microwave ablation (MWA) are a standard of care in the treatment of hepatocellular carcinoma (HCC). Currently, there is an increasing interest in cryotherapy, one of the oldest ablation techniques. It has some unique characteristics with regard to technology and mechanism of action. MATERIALS AND METHODS:  A systematic literature search using the terms cryotherapy, cryosurgery and cryoablation was performed...
April 17, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29664175/evaluation-of-the-value-of-staining-hair-samples-with-a-modified-wright-giemsa-stain-and-or-showing-illustrated-guidelines-for-the-microscopic-diagnosis-of-dermatophytosis-in-cats
#18
Rareş Căpitan, Carlo Schievano, Chiara Noli
BACKGROUND: Direct examination of the hair is a simple diagnostic test for the diagnosis of dermatophytosis; training is needed to use this test. HYPOTHESIS/OBJECTIVES: To evaluate whether use of modified Wright-Giemsa blue stain and/or photographic images of infected and uninfected hairs improved the user's ability to identify infected or uninfected hairs. ANIMALS: Ten cats with, and 10 cats without, dermatophytosis due to Microsporum canis (n = 20)...
April 17, 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/29664130/time-to-redefine-the-intramammary-lymph-node-as-a-separate-entity
#19
M Green, H Tafazal, B Swati, R Vidya
The lymphatic drainage for the majority of primary breast tumours is to the axillary lymph nodes (ALNs). Some, however drain to the so-called extra-axillary basins, namely the internal mammary, supra- and infraclavicular regions. Another potential drainage route includes the intramammary lymph nodes (IMLNs). Current guidance suggests IMLNs should be considered as part of the axillary group, potentially affecting axillary management. However, due to evolution in imaging and advancement in technology, IMLNs may now be distinguished more accurately pre-operatively...
April 17, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29663986/-interpretation-of-2018-guidelines-for-the-early-management-of-patients-with-acute-ischemic-stroke
#20
Gang Wang, Bangjiang Fang, Xuezhong Yu, Zhijun Li
In 2018, the American Heart Association/American Stroke Association (AHA/ASA) has developed the latest 2018 guidelines for the early management of patients with acute ischemic stroke (AIS), based on the latest evidences. The 2018 guidelines including recommendations on pre-hospital and in-hospital management treatment, has revised and add new recommendations from 2013 guideline. The major changes in 2018 guideline involve applications of brain imaging in early stage, intravenous thrombolysis and mechanical thrombectomy, et al...
April 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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