Wannes Van Holm, Naiera Zayed, Katalina Lauwens, Mehraveh Saghi, Jakob Axelsson, Merve Kübra Aktan, Annabel Braem, Kenneth Simoens, Lotte Vanbrabant, Paul Proost, Bram Van Holm, Piet Maes, Nico Boon, Kristel Bernaerts, Wim Teughels
Several inflammatory diseases are characterized by a disruption in the equilibrium between the host and its microbiome. Due to the increase in resistance, the use of antibiotics for the widespread, nonspecific killing of microorganisms is at risk. Pro-microbial approaches focused on stimulating or introducing beneficial species antagonistic toward pathobionts may be a viable alternative for restoring the host-microbiome equilibrium. Unfortunately, not all potential probiotic or synbiotic species and even subspecies (to strain level) are equally effective for the designated pathology, leading to conflicting accounts of their efficacy...
April 15, 2024: Probiotics and Antimicrobial Proteins