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Osteonecrosis of knee

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https://www.readbyqxmd.com/read/28671294/osteonecrosis-after-intranasal-injection-with-bevacizumab-in-treating-hereditary-hemorrhagic-telangiectasia-a-case-report
#1
Johan Steineger, Else Merckoll, John Magnar Slåstad, Erik Fink Eriksen, Ketil Heimdal, Sinan Dheyauldeen
Intranasal bevacizumab injections have been used in treating hereditary hemorrhagic telangiectasia (HHT)-related epistaxis since 2009. It is believed to be a safe and effective treatment for a selected group of HHT patients in reducing frequency and intensity of epistaxis, with few or none adverse effects. In this case report, however, we will describe a patient who developed bilateral osteonecrosis in the knees while undergoing regular intranasal submucosal bevacizumab injections. Although osteonecrosis previously has been documented in patients receiving bevacizumab intravenously in oncologic doses, thus far it has not been reported in patients treated with intranasal submucosal injections...
July 3, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28632664/outcome-of-low-intensity-pulsed-ultrasound-lipus-for-opening-wedge-high-tibial-osteotomy
#2
Ryusuke Saito, Tsuyoshi Nagase, Tomohiko Tateishi, Sadanori Shimizu, Takuya Kato, Teruhiko Nakagawa, Masamitsu Tsutiya
OBJECTIVE: Opening Wedge High Tibial Osteotomy (OWHTO) for knee osteoarthritis and for osteonecrosis has reported good results. Use of low intensity pulsed ultrasound (LIPUS) after OWHTO had become an option for the treatment of OWHTO since April 2016. The purpose of this study was to examine whether LIPUS has an accelerating effect on synostosis after OWHTO. MATERIALS AND METHODS: The control subjects were 24 patients with a total of 26 knees (9 male with knees and 15 female with 17 knees treated) treated with OWHTO only...
July 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28599878/responsiveness-of-the-knee-injury-and-osteoarthritis-outcome-score%C3%A2-koos-and-the-oxford-knee-score-oks-in-japanese-patients%C3%A2-with-high-tibial-osteotomy
#3
Sabine Goldhahn, Ryohei Takeuchi, Norimasa Nakamura, Ryuichi Nakamura, Takeshi Sawaguchi
BACKGROUND: To assess responsiveness of the Japanese Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Oxford Knee Score (OKS) in patients undergoing open-wedge HTO to treat knee osteoarthritis and/or osteonecrosis. METHODS: Patients completed a set of questionnaires before HTO surgery (baseline) and 1 year after surgery. The questionnaires comprised the validated Japanese versions of the KOOS, the OKS, and the SF-36v2 and a visual analogue scale (VAS) for local knee pain and general pain...
June 6, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28530464/osteonecrosis-in-sle-prevalence-patterns-outcomes-and-predictors
#4
D D Gladman, N Dhillon, J Su, M B Urowitz
Objective Osteonecrosis is a serious comorbidity in patients with systemic lupus erythematosus. The aims of this study were to describe the prevalence of symptomatic osteonecrosis, determine the pattern of joint involvement, identify the outcomes and investigate predictive factors in a large cohort of patients with systemic lupus erythematosus followed prospectively. Methods At the Toronto Lupus Clinic patients have been followed prospectively according to a standard protocol since 1970. Osteonecrosis is recorded if patients are symptomatic and is confirmed by imaging...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28521072/early-presentation-of-osteonecrosis-in-acute-lymphoblastic-leukemia-two-children-from-the-nordic-and-baltic-cohort
#5
Signe Sloth Mogensen, Arja Harila-Saari, Thomas Leth Frandsen, Päivi Lähteenmäki, Anders Castor, Ia Kohonen, Kjeld Schmiegelow, Outi Mäkitie
Osteonecrosis (ON) is usually considered treatment related in patients with acute lymphoblastic leukemia (ALL). We report two patients with presentation of ON at the time of ALL diagnosis. Both were females and diagnosed with ALL at age 8 and 14 years. In the latter, some symptoms and radiologically verified ON in both knees were still present after the end of ALL therapy. No pediatric patients have previously been reported with ON presenting before initiation of ALL therapy.
May 18, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28488164/up-to-twelve-year-follow-up-of-the-oxford-phase-three-unicompartmental-knee-replacement-in-china-seven-hundred-and-eight-knees-from-an-independent-centre
#6
Huaming Xue, Yihui Tu, Tong Ma, Tao Wen, Tao Yang, Minwei Cai
PURPOSE: There have been few large sample studies reporting the midterm outcome of Oxford phase 3 unicompartmental knee arthroplasty (UKA) in Asian patients. METHODS: The study included 708 consecutive medial Oxford UKAs between February 2005 and May 2014 in Chinese patients. All cases were performed for the recommended indications with a minimally-invasive surgical technique. The functional and radiological outcomes were subsequently examined. In particular, we divided patients into the spontaneous osteonecrosis of the knee (SONK) group and the osteoarthritis (OA) group...
May 10, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28452860/osteonecrosis-of-the-shoulders-in-pediatric-patients-treated-for-leukemia-or-lymphoma-single-institutional-experience
#7
Sue C Kaste, Brian M DeFeo, Michael D Neel, Kenneth S Weiss, Israel Fernandez-Pineda, Kiri K Ness
BACKGROUND: Osteonecrosis of the hips and knees is an often debilitating adverse event in children treated with glucocorticoids for leukemia and lymphoma but the impact of shoulder involvement has been understudied. Thus, we investigated the severity and functional impairment of shoulder osteonecrosis in a well-characterized population of pediatric patients treated for acute lymphoblastic leukemia or lymphoma. METHODS: We retrospectively reviewed orthopaedic clinic and physical therapy evaluations to determine range of motion (ROM), pain, and impact of magnetic resonance-defined osteonecrosis (ON) on activities of daily living...
April 27, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28425303/a-retrospective-study-assessing-safety-and-efficacy-of-bipolar-radiofrequency-ablation-for-knee-chondral-lesions
#8
Monther Gharaibeh, Andras Szomor, Darren B Chen, Samuel J MacDessi
OBJECTIVE: Bipolar radiofrequency (bRF) ablation is gaining popularity as a treatment modality for unstable knee chondral lesions of the knee. Limited reports of osteonecrosis and chondrolysis have been published; however, there is little data examining the safety of this treatment in larger series. This study aims to evaluate the safety and efficacy of bRF in the treatment of chondral lesions encountered during knee arthroscopy. DESIGN: A retrospective evaluation of adverse outcomes in patients that underwent treatment of chondral lesions using bRF was undertaken...
April 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28425055/what-are-the-oncologic-and-functional-outcomes-after-joint-salvage-resections-for-juxtaarticular-osteosarcoma-about-the-knee
#9
Jing Li, Zhen Wang, Chuanlei Ji, Guojing Chen, Dong Liu, Haodong Zhu
BACKGROUND: Joint salvage surgery for patients with juxtaarticular osteosarcoma remains challenging, especially when the tumor invades the epiphysis. Because patients are surviving longer with current chemotherapy regimens, it is advantageous to retain native joints if possible, especially in young patients. However, the results using joint-preserving tumor resections in this context have not been well characterized. QUESTIONS/PURPOSES: (1) What are the functional outcomes after limb salvage surgery at a minimum of 3 years? (2) What are the oncologic outcomes? (3) Is joint salvage surgery for epiphyseal tumors associated with an increased risk of local recurrence compared with metaphyseal tumors not invading the epiphysis? (4) What are the complications associated with joint salvage surgery? METHODS: Between 2004 and 2013, we treated 117 patients with juxtaarticular osteosarcoma; of those, 43 (38%) were treated with joint salvage surgery, and 41 (95%) of the 43 patients are included in our study...
April 19, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28399605/cementless-total-knee-arthroplasty-in-patients-older-than-75-years
#10
Jared M Newman, Anton Khlopas, Morad Chughtai, Chukwuweike U Gwam, Jaydev B Mistry, George A Yakubek, Steven F Harwin, Michael A Mont
Some surgeons have been hesitant to use cementless fixation for total knee arthroplasty (TKA) in elderly patients due to concerns regarding successful bone biological fixation. Therefore, this study evaluated: (1) implant survivorship, (2) functional outcomes, (3) radiographic outcomes, and (4) complications in patients over 75 years of age who underwent cementless total knee arthroplasty. A total of 134 patients (142 TKAs) older than 75 years at a single institution between June 2008 and June 2014 were retrospectively reviewed...
April 11, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28378451/association-between-medial-meniscus-extrusion-and-spontaneous-osteonecrosis-of-the-knee
#11
Tadashi Yasuda, Satoshi Ota, Satoshi Fujita, Eijiro Onishi, Koichi Iwaki, Hiroshi Yamamoto
AIM: Medial meniscus tear has been proposed as a potential etiology of spontaneous osteonecrosis of the knee (SONK). Disruption of collagen fibers within the meniscus causes meniscal extrusion, which results in alteration in load distribution in the knee. Our purpose was to determine whether the extent of medial meniscus extrusion correlates with the severity of SONK in the medial femoral condyle. METHODS: Radiological stage of SONK and femorotibial angle (FTA) were determined on knee radiographs...
April 5, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28365171/midterm-clinical-outcomes-and-mr-imaging-changes-after-transcatheter-arterial-embolization-as-a-treatment-for-mild-to-moderate-radiographic-knee-osteoarthritis-resistant-to-conservative-treatment
#12
Yuji Okuno, Amine M Korchi, Takuma Shinjo, Shojiro Kato, Takao Kaneko
PURPOSE: To describe the safety and efficacy of transcatheter arterial embolization for mild to moderate radiographic knee osteoarthritis (OA) that is resistant to conservative treatment. MATERIALS AND METHODS: This prospective study included 72 patients (95 knees) with OA of Kellgren-Lawrence (KL) grade 1-3 and persisting moderate to severe pain that was resistant to conservative management who were treated with transcatheter arterial embolization between July 2012 and March 2016...
March 29, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28364675/correlation-between-gait-analysis-and-clinical-questionnaires-in-patients-with-spontaneous-osteonecrosis-of-the-knee
#13
Ronen Debi, Amit Mor, Avi Elbaz, Ganit Segal, Omri Lubovsky, Gadi Kahn, Bezalel Peskin, Yiftah Beer, Ehud Atoun
BACKGROUND: Spontaneous osteonecrosis of the knee is usually verified by magnetic resonance imaging accompanied by clinical questionnaires to assess the level of pain and functional limitation. There is a lack however, in an objective functional test that will reflect the functional severity of spontaneous osteonecrosis of the knee. The purpose of the current study was to examine the correlation between spatiotemporal gait parameters and clinical questionnaires in patients with spontaneous osteonecrosis of the knee...
May 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28355130/value-of-whole-body-magnetic-resonance-imaging-for-screening-multifocal-osteonecrosis-in-patients-with-polymyositis-dermatomyositis
#14
Huang Zhen-Guo, Yang Min-Xing, Chen Xiao-Liang, Yan Ran, Chen He, Gao Bao-Xiang, Yin Li-Guo, Shi Kai-Ning, Queenie Chan, Wang Guo-Chun
OBJECTIVE: To assess the value of coronal short-tau inversion recovery whole-body MRI (STIR-WBMRI) for screening osteonecrosis in patients with polymyositis (PM)/dermatomyositis (DM). METHODS: The imaging and medical records of 129 patients with PM/DM who met the Bohan and Peter diagnostic criteria were retrospectively analyzed. STIR-WBMRI was performed in all patients. 18 patients had follow-up STIR-WBMRI. 12 patients underwent regional knee and/or hip MRI while 25 patients underwent radiography of the lower extremities...
May 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28330798/knee-osteoarthritis-degenerative-meniscal-lesion-and-osteonecrosis-of-the-knee-can-a-simple-gait-test-direct-us-to-a-better-clinical-diagnosis
#15
R Debi, A Elbaz, A Mor, G Kahn, B Peskin, Y Beer, G Agar, G Morag, G Segal
INTRODUCTION: The purpose of the current study was to compare the gait patterns in patients with three differing knee pathologies - knee osteoarthritis (OA), degenerative meniscal lesion (DML) and spontaneous osteonecrosis of the knee (SONK) and a group of healthy controls. HYPOTHESIS: A simple gait test will detect differences between different knee pathologies. MATERIAL AND METHODS: Forty-seven patients with bilateral knee OA, 47 patients with DML, 28 patients with SONK and 27 healthy controls were included in this analysis...
June 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28328178/clinical-characteristics-of-multifocal-osteonecrosis-in-korean-patients-with-rheumatic-disease
#16
Hye-Jin Jeong, Dam Kim, Soo-Kyung Cho, Yeesuk Kim, Sang-Cheol Bae, Yoon-Kyoung Sung
AIM: Osteonecrosis (ON), also known as avascular necrosis, is an important cause of physical disability in rheumatic disease. When this condition affects multiple structures, disability is increased. The purpose of this study was to describe the clinical characteristics of Korean patients with multifocal ON associated with rheumatic disease and to compare them with those of previously reported cases. METHODS: We reviewed the clinical characteristics of eight Korean patients with multifocal ON, defined by the involvement of three or more anatomic sites, associated with rheumatic disease in a single referral academic hospital, and compared them with those of 19 similar cases previously reported in the literature...
March 22, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28325693/surgical-technique-and-clinical-outcomes-of-retrograde-osteochondral-autograft-transfer-for-osteochondral-lesions-of-the-tibial-plateau
#17
Hiromitsu Yabumoto, Yasuaki Nakagawa, Shogo Mukai, Takahiko Saji, Takashi Nakamura
PURPOSE: To present the surgical technique, clinical outcomes, and poor prognostic factors of arthroscopic retrograde osteochondral autograft transfer of the tibial plateau. METHODS: Twelve patients (6 men, 6 women; mean age, 38.7 years) with tibial plateau osteochondral lesions underwent surgery. The primary diseases were osteonecrosis in 4 cases, cartilage injuries in 6, and postfractures of the tibial plateau in 2. Clinical outcomes were evaluated preoperatively and postoperatively according to the International Knee Documentation Committee score and the Japanese Orthopaedic Association score...
March 18, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28244910/subsequent-total-joint-arthroplasty-after-primary-total-knee-or-hip-arthroplasty-a-40-year-population-based-study
#18
Thomas L Sanders, Hilal Maradit Kremers, Cathy D Schleck, Dirk R Larson, Daniel J Berry
BACKGROUND: Despite the large increase in total hip arthroplasties and total knee arthroplasties, the incidence and prevalence of additional contralateral or ipsilateral joint arthroplasty are poorly understood. The purpose of this study was to determine the rate of additional joint arthroplasty after a primary total hip arthroplasty or total knee arthroplasty. METHODS: This historical cohort study identified population-based cohorts of patients who underwent primary total hip arthroplasty (n = 1,933) or total knee arthroplasty (n = 2,139) between 1969 and 2008...
March 1, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28203389/mr-appearance-of-the-temporal-evolution-and-resolution-of-spontaneous-osteonecrosis-of-the-knee-a-case-report
#19
Mats Geijer, Jan Jureus, Mari Hanni, Adel Shalabi
Spontaneous osteonecrosis of the knee (SONK) is a feared condition of unknown cause, in its classic form appearing in the medial femoral condyle in middle-aged or elderly subjects. Diagnosis with radiography is notoriously difficult with a long latency before typical changes appear. Magnetic resonance imaging (MRI) is regarded as a diagnostic tool with the possibility to give an earlier diagnosis with improved chances for treatment. However, also with MRI there may be an initial diagnostic blind spot before typical changes appear...
February 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28169099/the-role-of-medial-meniscus-posterior-root-tear-and-proximal-tibial-morphology-in-the-development-of-spontaneous-osteonecrosis-and-osteoarthritis-of-the-knee
#20
Ryota Yamagami, Shuji Taketomi, Hiroshi Inui, Keitaro Tahara, Sakae Tanaka
BACKGROUND: Medial meniscus posterior root tear (MMPRT) has been reported to play a key role in the development of spontaneous osteonecrosis of the knee (SONK) and osteoarthritis (OA) of the knee. However, little is known about the differences in the development of SONK and OA after MMPRT. The purpose of this study was to investigate the factors contributing to the development of these conditions. METHODS: We evaluated the existence of MMPRT and the extent of medial meniscal extrusion in preoperative magnetic resonance images and proximal tibial morphology in radiographs of 45 patients with SONK and 104 patients with OA who underwent knee surgery...
February 3, 2017: Knee
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