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Osteonecrosis of knee

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https://www.readbyqxmd.com/read/27905865/transient-bone-marrow-edema-syndrome-versus-osteonecrosis-perfusion-patterns-at-dynamic-contrast-enhanced-mr-imaging-with-high-temporal-resolution-can-allow-differentiation
#1
Tobias Geith, Thomas Niethammer, Stefan Milz, Olaf Dietrich, Maximilian Reiser, Andrea Baur-Melnyk
Purpose To prospectively evaluate the perfusion patterns at quantitative dynamic contrast material-enhanced (DCE) magnetic resonance (MR) imaging of transient bone marrow edema syndrome (TBMES) and avascular osteonecrosis. Materials and Methods Institutional review board approval and written informed consent were obtained. Thirty-two patients (21 men, 11 women; mean age, 48 years; 26 hips, 10 knees) underwent conventional MR imaging and a dynamic contrast-enhanced three-dimensional spoiled gradient-echo sequence at 3 T...
December 1, 2016: Radiology
https://www.readbyqxmd.com/read/27867692/osteonecrosis-of-both-knees-in-a-woman-with-crohn-s-disease
#2
Mara Barbosa, José Cotter
Osteonecrosis is a very rare complication of Crohn's disease (CD). It is not clear if it is related to corticosteroid therapy or if it occurs as an extraintestinal manifestation of inflammatory bowel disease. We present the case of a patient with CD who presented with osteonecrosis of both knees. A 22 years old woman was diagnosed with CD in April 2012 (Montreal Classification A2L1 + L4B3p). She was started on prednisolone (40 mg/d), azathioprine (100 mg/d) and messalazine (3 g/d). In July 2012, due to active perianal disease, infliximab therapy was initiated...
November 6, 2016: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27842560/a-non-invasive-home-based-biomechanical-therapy-for-patients-with-spontaneous-osteonecrosis-of-the-knee
#3
Ehud Atoun, Amit Mor, Ganit Segal, Ronen Debi, Dan Grinberg, Yeshaiau Benedict, Nimrod Rozen, Yiftah Beer, Avi Elbaz
BACKGROUND: The purpose of the current study was to examine the effect of a non-invasive, home-based biomechanical treatment program for patients with spontaneous osteonecrosis of the knee (SONK). METHODS: Seventeen patients with SONK, confirmed by MRI, participated in this retrospective analysis. Patients underwent a spatiotemporal gait analysis and completed the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and the Short-Form-36 (SF-36)...
November 14, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27756382/post-arthroscopic-osteonecrosis-of-the-medial-tibial-plateau-a-case-series
#4
Axel Marx, Alexander Beier, Pouria Taheri, Martin Röpke, Thomas Kalinski, Andreas M Halder
BACKGROUND: Avascular necrosis after arthroscopic surgery of the knee has already been published. The purpose of this article is to report on the frequently misdiagnosed entity of osteonecrosis of the medial tibial plateau. CASE PRESENTATION: Charts and radiographs of a consecutive series with isolated medial tibial plateau osteonecrosis were analyzed. The criterion for inclusion was the absence of trauma. Six caucasian female patients with an average age of 76...
October 19, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27743304/no-decrease-in-knee-survivorship-or-outcomes-scores-for-patients-with-hiv-infection-who-undergo-tka
#5
Kimona Issa, Todd P Pierce, Steven F Harwin, Anthony J Scillia, Anthony Festa, Michael A Mont
BACKGROUND: HIV is prevalent worldwide and numerous patients with this diagnosis ultimately may become candidates for TKA. Although some studies have suggested that complications are more common in patients with HIV who undergo TKA, these studies largely were done before the contemporary era of HIV management; moreover, it is unclear whether patients with HIV achieve lower patient-reported outcome scores or inferior implant survivorship. QUESTIONS/PURPOSES: We asked whether there were any differences in the outcomes of patients with HIV without hemophilia who undergo TKA compared with a matched control cohort in terms of: (1) patient-reported outcomes; (2) implant survivorship; and (3) complication rates...
October 14, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27676730/multifocal-osteonecrosis-revealing-an-antiphospholipid-syndrome-case-report
#6
Sophie Legrève
OBJECTIVE: Multifocal osteonecrosis is rare. A zone of epiphyseal bone-marrow necrosis of three or more joints characterizes it. The most common risk factors are glucocorticoids intake and alcoholism. However, there is a series of other causes that could be incriminated in osteonecrosis, among which antiphospholipid syndrome. This case report, illustrates a primary antiphospholipid syndrome with only one clinical manifestation: multifocal osteonecrosis. OBSERVATIONS: A 30-year-old woman, with a medical history of left total hip replacement (THR), presents with severe right coxalgia and pain in both knees and shoulders...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27592357/can-a-biomimetic-osteochondral-scaffold-be-a-reliable-alternative-to-prosthetic-surgery-in-treating-late-stage-sponk
#7
M Berruto, P Ferrua, F Uboldi, S Pasqualotto, F Ferrara, G Carimati, E Usellini, M Delcogliano
BACKGROUND: This study aimed to assess the reliability of the Maioregen® biomimetic osteochondral scaffold (Finceramica Faenza SpA, Faenza, Italy) as a salvage and joint-preserving procedure in the treatment of late-stage osteonecrosis of the knee. METHODS: Eleven active patients aged under 65years and presenting with clinical and radiological signs of SPONK were treated with Maioregen®. All were clinically evaluated pre-operatively and yearly thereafter for a minimum of two years...
December 2016: Knee
https://www.readbyqxmd.com/read/27519911/osteonecrosis-detected-by-whole-body-magnetic-resonance-in-patients-with-hodgkin-lymphoma-treated-by-beacopp
#8
Domenico Albano, Caterina Patti, Ludovico La Grutta, Emanuele Grassedonio, Antonino Mulè, Giuseppe Brancatelli, Roberto Lagalla, Massimo Midiri, Massimo Galia
OBJECTIVES: The purpose of our retrospective review of prospectively acquired Whole Body Magnetic Resonance (WB-MRI) scans was to assess the incidence of osteonecrosis in patients who received different chemotherapies. METHODS: We evaluated the WB-MRI scans performed on 42 patients with Hodgkin Lymphoma treated by three chemotherapy regimens (6ABVD, 2ABVD + 4BEACOPP, 2ABVD + 8BEACOPP), excluding patients with the main risk factors for osteonecrosis. RESULTS: Six out of seven patients (86 %) who received eight BEACOPP and one out of five patients (20 %) treated by four BEACOPP presented osteonecrosis, with a statistically significant difference of frequency between the two groups of patients (p < 0...
August 13, 2016: European Radiology
https://www.readbyqxmd.com/read/27459136/distribution-of-hip-pain-in-patients-with-idiopathic-osteonecrosis-of-the-femoral-head
#9
Junichi Nakamura, Kenta Konno, Sumihisa Orita, Shigeo Hagiwara, Tomonori Shigemura, Takayuki Nakajima, Takane Suzuki, Ryuichiro Akagi, Seiji Ohtori
OBJECTIVE: To determine the distribution of referred hip pain in patients with idiopathic osteonecrosis of the femoral head (ION). METHODS: We prospectively documented 119 hips in 90 patients with ION (mean age 51 years). Patients identified the location of pain originating in their hip on a drawing of the body. Osteoarthritis of the hip (OA) was used as a historical cohort. RESULTS: Referral of pain originating from the hip in patients with ION was 93% (111 hips) to the groin, 68% (81 hips) to the knee, 36% (43 hips) to the anterior thigh, 34% (40 hips) to the buttock, 18% (22 hips) to the lower leg, 9% (11 hips) to the greater trochanter, and 8% (9 hips) to the low back...
July 26, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27454596/spleen-uptake-on-bone-scan-after-frequent-platelet-and-rbc-transfusions
#10
Pierre De Marini, Annegret Laplace, Julien Matuszak, Luc-Matthieu Fornecker, Izzie Jacques Namer
A 21-year-old man, allogeneic hematopoietic stem cell transplantation recipient, was referred to our nuclear medicine department for a suspicion of knee osteonecrosis. Bone scan with Tc-HMDP did not show abnormal bone uptake but an intense spleen accumulation. F-FDG PET/CT performed on the same day showed no pathological spleen uptake. The patient had secondary hemochromatosis resulting from frequent transfusions in the setting of a chronic graft versus host disease with hemolysis and thrombocytopenia. The last RBC and platelet transfusions were performed 9 and 2 days before the examination, respectively...
October 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27404962/the-pathogenesis-of-multifocal-osteonecrosis
#11
Wei Sun, Zhencai Shi, Fuqiang Gao, Bailiang Wang, Zirong Li
Our objective was to study the incidence, etiology, and diagnosis of multifocal osteonecrosis (MFON) and its treatment options to facilitate an earlier diagnosis and to optimize treatment. A radiological investigation was performed in osteonecrosis patients with a high risk of MFON for a more accurate diagnosis between January 2010 and June 2015. For patients with osteonecrosis of both the hip and knee joints or for patients with a history of corticosteroid use or alcohol abuse who had osteonecrosis of one or more joints in the shoulder, ankle, wrist or elbow, magnetic resonance imaging (MRI) was also performed on other joints, regardless of whether these joints were symptomatic...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27399818/spontaneous-osteonecrosis-of-the-knee
#12
Jason L Zaremski, Kevin R Vincent
No abstract text is available yet for this article.
July 2016: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/27389113/is-genicular-nerve-radiofrequency-ablation-safe-a-literature-review-and-anatomical-study
#13
Soo Yeon Kim, Phuong Uyen Le, Boleslav Kosharskyy, Alan D Kaye, Naum Shaparin, Sherry A Downie
Genicular nerve radiofrequency ablation (RFA) has recently gained popularity as an intervention for chronic knee pain in patients who have failed other conservative or surgical treatments. Long-term efficacy and adverse events are still largely unknown. Under fluoroscopic guidance, thermal RFA targets the lateral superior, medial superior, and medial inferior genicular nerves, which run in close proximity to the genicular arteries that play a crucial role in supplying the distal femur, knee joint, meniscus, and patella...
July 2016: Pain Physician
https://www.readbyqxmd.com/read/27318670/percutaneous-rotational-osteotomy-of-the-femur-utilizing-an-intramedullary-rod
#14
Peter M Stevens, Christian J Gaffney, Heather Fillerup
The purpose is to describe the technique and report the results and complications of percutaneous femoral rotational osteotomy, secured with a trochanteric-entry, locked intramedullary rod, in adolescents with femoral anteversion. Our series comprised an IRB approved, retrospective, consecutive series of 85 osteotomies (57 patients), followed to implant removal. The average age at surgery was 13.3 years (range 8.8-18.3) with a female-to-male ratio of 2.8:1. The minimum follow-up was 2 years. Eighty-three osteotomies healed primarily...
August 2016: Strategies in Trauma and Limb Reconstruction
https://www.readbyqxmd.com/read/27242941/a-case-of-spontaneous-osteonecrosis-of-the-knee-with-early-and-simultaneous-involvement-of-the-medial-femoral-condyle-and-medial-tibial-plateau
#15
Shinya Fujita, Yuji Arai, Kuniaki Honjo, Shuji Nakagawa, Toshikazu Kubo
Spontaneous osteonecrosis of the knee (SPONK) usually involves a single condyle, most often the medial femoral condyle (MFC). Involvement of the medial tibial plateau (MTP) is less common, occurring in about 2% of knees with SPONK. Early onset SPONK on the ipsilateral side of the medial compartment is very rare, with, to our knowledge, only four cases reported to date. We describe a very rare case of SPONK with early simultaneous development in the MFC and MTP. Serial plain radiographs and magnetic resonance imaging showed that SPONK in both condyles followed a similar progressive course...
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27238963/efficacy-and-safety-of-fulranumab-as-monotherapy-in-patients-with-moderate-to-severe-chronic-knee-pain-of-primary-osteoarthritis-a-randomised-placebo-and-active-controlled-trial
#16
A J Mayorga, S Wang, K M Kelly, J Thipphawong
AIMS: The efficacy and safety of monotherapy with fulranumab, a monoclonal antibody that neutralises human nerve growth factor (NGF), was evaluated compared with placebo and an active comparator, controlled-release (CR) oxycodone, in patients with moderate to severe chronic knee pain of primary osteoarthritis (OA). METHODS: In this phase-2, double-blind (DB), double-dummy, placebo- and active-controlled study, patients (40-80 years) were randomised (1:1:1:1) to placebo, fulranumab 3 or 9mg every 4 weeks (Q4 wk), or oxycodone CR twice-daily...
June 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27230994/symptomatic-knee-osteonecrosis-in-patients-with-systemic-lupus-erythematosus-a-case-control-study
#17
Lidan Zhao, Xiuhua Wu, Honghua Wu, Jinmei Su, Wen Zhang, Yan Zhao, Xuan Zhang, Wenjie Zheng
To explore the associated risk factors of symptomatic knee osteonecrosis (KON) in patients with systemic lupus erythematosus (SLE), we conducted a retrospective case-control study to compare the clinical and laboratory features between SLE patients with and without symptomatic KON matched by age and gender. Univariate and multivariate regression analyses were used to evaluate possible associated risk factors. Twenty (one male, nineteen females) out of 3941 lupus patients were identified as symptomatic KON, which was confirmed by magnetic resonance imaging...
August 2016: Rheumatology International
https://www.readbyqxmd.com/read/27198760/the-importance-of-early-diagnosis-in-spontaneous-osteonecrosis-of-the-knee-a-case-series-with-six-year-follow-up
#18
Robert W Jordan, Prasad Aparajit, Charles Docker, Umesh Udeshi, Mohi El-Shazly
BACKGROUND: Spontaneous osteonecrosis of the knee has an unknown aetiology. Management options include conservative, surgical and pharmacological interventions. The aim of this study was to report the experience of the authors in conservative management of SONK using non-operative measures by analysing the functional outcome and need for surgical intervention. MATERIALS AND METHODS: All patients treated for SONK between 1st August 2001 and 1st April 2014 were retrospectively reviewed...
August 2016: Knee
https://www.readbyqxmd.com/read/27135286/diseases-of-subchondral-bone-2
#19
Frantz Lerebours, Neal S ElAttrache, Bert Mandelbaum
Osteonecrosis of the knee can be divided into the following 3 categories: primary or Spontaneous osteonecrosis of the knee (SONK), secondary osteonecrosis (ON), and postarthroscopic osteonecrosis. Patient characteristics as well as underlying risk factors can help categorize the type of osteonecrosis and guide treatment. SONK was first described by Ahlback et al in 1968. It is described as a disease of subchondral bone that leads to focal ischemia and bone marrow edema, necrosis, and possible subsequent structural collapse...
June 2016: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/27114807/long-term-clinical-results-after-iloprost-treatment-for-bone-marrow-edema-and-avascular-necrosis
#20
Tim Claßen, Antonia Becker, Stefan Landgraeber, Marcel Haversath, Xinning Li, Christoph Zilkens, Rüdiger Krauspe, Marcus Jäger
The treatments of avascular osteonecrosis (AVN) include both conservative and surgical methods which are dependent on the stage and progression of the disease. The vasoactive-prostaglandin-analogue iloprost (PGI2) has been utilized in several areas of medicine and recently has been used for the treatment of AVN. A total of 108 patients with 136 osteonecrosis of different joints, etiology and severity were treated with iloprost. The mean follow-up was 49.71 months: range 15-96 months, and outcome measurements recorded regarding subjective complaints, visual analog scale (pain), function and survival...
March 21, 2016: Orthopedic Reviews
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