Logan Stuck, Eveline Klinkenberg, Nahid Abdelgadir Ali, Egbal Ahmed Basheir Abukaraig, Yaw Adusi-Poku, Zeleke Alebachew Wagaw, Razia Fatima, Nathan Kapata, Pascalina Kapata-Chanda, Bruce Kirenga, Llang B Maama-Maime, Sayoki G Mfinanga, Sizulu Moyo, Lindiwe Mvusi, Ndahafa Nandjebo, Hai Viet Nguyen, Hoa Binh Nguyen, Joshua Obasanya, Bashorun Adedapo Olufemi, Philip Patrobas Dashi, Thato J Raleting Letsie, Nunurai Ruswa, Elizeus Rutebemberwa, Mbazi Senkoro, Tieng Sivanna, Huot Chan Yuda, Irwin Law, Ikushi Onozaki, Edine Tiemersma, Frank Cobelens
BACKGROUND: Subclinical pulmonary tuberculosis, which presents without recognisable symptoms, is frequently detected in community screening. However, the disease category is poorly clinically defined. We explored the prevalence of subclinical pulmonary tuberculosis according to different case definitions. METHODS: We did a one-stage individual participant data meta-analysis of nationally representative surveys that were conducted in countries with high incidence of tuberculosis between 2007 and 2020, that reported the prevalence of pulmonary tuberculosis based on chest x-ray and symptom screening in participants aged 15 years and older...
March 12, 2024: Lancet Infectious Diseases