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https://www.readbyqxmd.com/read/29145687/foot-strike-patterns-differ-between-children-and-adolescents-growing-up-barefoot-vs-shod
#1
Karsten Hollander, Johanna Elsabe de Villiers, Ranel Venter, Susanne Sehner, Karl Wegscheider, Klaus-Michael Braumann, Astrid Zech
Effects of early and permanent footwear use are not well understood. The aim of this study was to investigate the effects of habituation to footwear on foot strike patterns of children and adolescents. Healthy habitually barefoot and shod participants (aged 6-18 years) from South Africa (n=288) and Germany (n=390) performed multiple 20-m jogging and running trials with and without shoes. Each foot strike was captured using a high-speed camera to determine a rearfoot or non-rearfoot strike. The probability of a rearfoot strike in both cohorts and each age was analyzed by using a mixed-effects logistic regression adjusted for possible confounders...
November 16, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29145465/hospital-associated-methicillin-resistant-staphylococcus-aureus-a-cross-sectional-analysis-of-risk-factors-in-south-african-tertiary-public-hospitals
#2
Liliwe L Shuping, Lazarus Kuonza, Alfred Musekiwa, Samantha Iyaloo, Olga Perovic
INTRODUCTION: Hospital-associated methicillin-resistant S. aureus (HA-MRSA) remains a significant cause of morbidity and mortality worldwide. We conducted a study to determine risk factors for HA-MRSA in order to inform control strategies in South Africa. METHODS: We used surveillance data collected from five tertiary hospitals in Gauteng and Western Cape provinces during 2014 for analysis. A case of HA-MRSA was defined as isolation of MRSA from a blood culture 48 hours after admission and/or if the patient was hospitalised in the six months prior to the current culture...
2017: PloS One
https://www.readbyqxmd.com/read/29145423/examining-the-relationships-between-body-image-eating-attitudes-bmi-and-physical-activity-in-rural-and-urban-south-african-young-adult-females-using-structural-equation-modeling
#3
Alessandra Prioreschi, Stephanie V Wrottesley, Emmanuel Cohen, Ankita Reddy, Rihlat Said-Mohamed, Rhian Twine, Stephen M Tollman, Kathleen Kahn, David B Dunger, Shane A Norris
The persistence of food insecurity, malnutrition, increasing adiposity, and decreasing physical activity, heightens the need to understand relationships between body image satisfaction, eating attitudes, BMI and physical activity levels in South Africa. Females aged 18-23 years were recruited from rural (n = 509) and urban (n = 510) settings. Body image satisfaction was measured using Stunkard's silhouettes, and the 26-item Eating Attitudes questionnaire (EAT-26) was used to evaluate participants' risk of disordered eating...
2017: PloS One
https://www.readbyqxmd.com/read/29143630/examining-the-mechanisms-by-which-women-s-status-and-empowerment-affect-skilled-birth-attendant-use-in-senegal-a-structural-equation-modeling-approach
#4
Kyoko Shimamoto, Jessica D Gipson
BACKGROUND: Despite the reduction in maternal deaths globally, maternal mortality rates remain unacceptably high, particularly in some regions of the world. In sub-Saharan Africa, maternal mortality rates have even increased recently, with 201,000 deaths in 2015 as compared to 179,000 in 2013. Use of a skilled birth attendant (SBA) at delivery has remained low, despite evidence of the effectiveness of SBAs in reducing maternal deaths. Women's empowerment is increasingly recognized as a key determinant of maternal health care-seeking and outcomes, yet empirical examinations of the linkages between women's empowerment and delivery care use are particularly limited, especially from sub-Saharan Africa...
November 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29143625/trends-in-hepatitis-b-virus-testing-practices-and-management-in-hiv-clinics-across-sub-saharan-africa
#5
REVIEW
Patrick A Coffie, Matthias Egger, Michael J Vinikoor, Marcel Zannou, Lameck Diero, Akouda Patassi, Mark H Kuniholm, Moussa Seydi, Guillaume Bado, Ponsiano Ocama, Monique I Andersson, Eugène Messou, Albert Minga, Philippa Easterbrook, Kathryn Anastos, François Dabis, Gilles Wandeler
BACKGROUND: Approximately 8% of HIV-infected individuals are co-infected with hepatitis B virus (HBV) in sub-Saharan Africa (SSA). Knowledge of HBV status is important to guide optimal selection of antiretroviral therapy (ART) and monitor/prevent liver-related complications. We describe changes in testing practices and management of HBV infection over a 3-year period in HIV clinics across SSA. METHODS: A medical chart review was conducted in large urban HIV treatment centers in Côte d'Ivoire (3 sites), Benin, Burkina Faso, Cameroon, Kenya, Senegal, South Africa, Togo, Uganda and Zambia (1 site each)...
November 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29142583/primary-gastric-burkitt-s-lymphoma
#6
Adnan Khan, Sarbiland Khan, Umair Arshad
The primary gastrointestinal non-Hodgkin's lymphoma is a rare entity. Burkitt's lymphoma (BL) is an aggressive form of B-cell lymphoma which is endemic in Africa, while in rest of the world non-endemic cases has been reported. Primary gastric BL is extremely rare and only around 53 cases have been reported till now. Here we present the case of a middle-aged male, immunocompetent who presented with anorexia weight loss and diarrhea. His upper gastrointestinal endoscopy and biopsy revealed a large primary gastric Burkitt lymphoma...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29141763/pilot-study-of-the-addition-of-mass-treatment-for-malaria-to-existing-school-based-programs-to-treat-neglected-tropical-diseases
#7
Lauren M Cohee, Moses Chilombe, Andrew Ngwira, Samuel K Jemu, Don P Mathanga, Miriam K Laufer
Malaria and neglected tropical diseases (NTDs), including schistosomiasis and soil transmitted helminths, threaten the health of school aged in sub-Saharan Africa. Established school-based mass drug administration (MDA) programs are used to control NTDs. Recent clinical trials have shown benefit of mass treatment of malaria in schools. The potential of adding malaria treatment to existing NTD programs has not been thoroughly evaluated. We offered malaria treatment with artemether-lumefantrine during routine NTD MDA and developed peer education programs in two primary schools in southern Malawi...
November 6, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29141739/advancing-global-health-through-development-and-clinical-trials-partnerships-a-randomized-placebo-controlled-double-blind-assessment-of-safety-tolerability-and-immunogenicity-of-plasmodium-falciparum-sporozoites-vaccine-for-malaria-in-healthy-equatoguinean
#8
Ally Olotu, Vicente Urbano, Ali Hamad, Martin Eka, Mwajuma Chemba, Elizabeth Nyakarungu, Jose Raso, Esther Eburi, Dolores O Mandumbi, Dianna Hergott, Carl D Maas, Mitoha O Ayekaba, Diosdado N Milang, Matilde R Rivas, Tobias Schindler, Oscar M Embon, Adam J Ruben, Elizabeth Saverino, Yonas Abebe, Natasha Kc, Eric R James, Tooba Murshedkar, Anita Manoj, Sumana Chakravarty, Minglin Li, Matthew Adams, Chris Schwabe, Luis Segura, Claudia Daubenberger, Marcel Tanner, Thomas L Richie, Peter F Billingsley, B Kim Lee Sim, Salim Abdulla, Stephen L Hoffman
Equatorial Guinea (EG) has implemented a successful malaria control program on Bioko Island. A highly effective vaccine would be an ideal complement to this effort and could lead to halting transmission and eliminating malaria. Sanaria(®)Plasmodium falciparum sporozoites (PfSPZ) Vaccine is being developed for this purpose. To begin the process of establishing the efficacy of and implementing a PfSPZ Vaccine mass vaccination program in EG, we decided to conduct a series of clinical trials of PfSPZ Vaccine on Bioko Island...
October 30, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29141723/emergence-epidemiology-and-transmission-dynamics-of-2009-pandemic-a-h1n1-influenza-in-kampala-uganda-2009-2015
#9
Matthew J Cummings, Barnabas Bakamutumaho, Wan Yang, Joseph F Wamala, John Kayiwa, Nicholas Owor, Barbara Namagambo, Timothy Byaruhanga, Allison Wolf, Julius J Lutwama, Jeffrey Shaman, Max R O'Donnell
In sub-Saharan Africa, little is known about the epidemiology of pandemic-prone influenza viruses in urban settings. Using data from a prospective sentinel surveillance network, we characterized the emergence, epidemiology, and transmission dynamics of 2009 pandemic A/H1N1 influenza (H1N1pdm09) in Kampala, Uganda. After virus introduction via international air travel from England in June 2009, we estimated the basic reproductive number in Kampala to be 1.06-1.13, corresponding to attack rates of 12-22%. We subsequently identified 613 cases of influenza in Kampala from 2009 to 2015, of which 191 (31...
October 30, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29141612/individual-level-and-community-level-determinants-of-cervical-cancer-screening-among-kenyan-women-a-multilevel-analysis-of-a-nationwide-survey
#10
Fentanesh Nibret Tiruneh, Kun-Yang Chuang, Peter Austin Morton Ntenda, Ying-Chih Chuang
BACKGROUND: Studies on the determinants of cervical cancer screening in sub-Saharan Africa have focused mostly on individual-level characteristics of cervical cancer screening. Therefore, in this study, we included both individual- and community-level indicators to examine the determinants of cervical cancer screening among Kenyan women. METHODS: We analyzed data from the 2014 Kenya Demographic and Health Surveys. Our analysis focused on 9016 married women of reproductive age (15-49 years)...
November 15, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29140871/hiv-prevalence-and-associated-risk-factors-among-men-who-have-sex-with-men-in-dar-es-salaam-tanzania
#11
Elia John Mmbaga, Kåre Moen, Germana Henry Leyna, Rose Mpembeni, Melkizedeck Thomas Leshabari
INTRODUCTION: Limited studies and differential risk behaviours among men who have sex with men(MSM) in Africa calls for population specific studies. We present results from the largest integrated bio-behavioural survey among MSM in Africa to inform programming. METHODS: This was a cross-sectional study utilizing respondent driven sampling to recruit MSM aged 18 and above. Data on socio-demographic characteristics and HIV-related risks were collected and all participants were tested for HIV, Herpes Simplex Virus Type-2 (HSV-2), Hepatitis-B Virus (HBV) and Syphilis...
November 13, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29140587/comparison-of-haematology-and-biochemistry-parameters-in-healthy-south-african-infants-with-laboratory-reference-intervals
#12
B Schmidt, M Tameris, H Geldenhuys, A Luabeya, E Bunyasi, T Hawkridge, J B McClain, H Mahomed, T J Scriba, H McShane, M Hatherill
OBJECTIVE: Paediatric laboratory reference intervals used in Africa and Asia may be derived from historical intervals of predominantly Caucasian infants in Europe or North America. These intervals may therefore not be compatible with the range of normality for developing country populations. We aimed to compare haematology and biochemistry parameters in healthy South African infants with local laboratory reference intervals. METHODS: We compared the baseline haematology and biochemistry results of 634 (316 male and 318 female) HIV-unexposed infants, aged 3-6 months, living in a rural area of the Western Cape Province, South Africa, against laboratory reference intervals supplied by the South African National Health Laboratory Services (NHLS)...
November 15, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29140229/epidemiology-of-imported-malaria-cases-in-japan-2006-2014-a-sentinel-traveler-surveillance-approach
#13
Atsuhiro Kanayama, Yuzo Arima, Tamano Matsui, Koki Kaku, Hitomi Kinoshita, Kazunori Oishi
Malaria continues to be imported into Japan. To better assess the risk of imported malaria, we describe malaria species, suspected country/area of infection (accounting for the number of travelers), demographic characteristics, clinical manifestation, and healthcare access, based on the national surveillance data from 2006 to 2014. Among 557 cases, the median age was 33 years (range: 1-83 years), and 76% were male; 306 (55%) were classified as Japanese based on the reported name. The majority were Plasmodium falciparum infections (58%), followed by Plasmodium vivax infections (30%)...
November 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29139110/unconditional-cash-transfers-for-reducing-poverty-and-vulnerabilities-effect-on-use-of-health-services-and-health-outcomes-in-low-and-middle-income-countries
#14
REVIEW
Frank Pega, Sze Yan Liu, Stefan Walter, Roman Pabayo, Ruhi Saith, Stefan K Lhachimi
BACKGROUND: Unconditional cash transfers (UCTs; provided without obligation) for reducing poverty and vulnerabilities (e.g. orphanhood, old age or HIV infection) are a type of social protection intervention that addresses a key social determinant of health (income) in low- and middle-income countries (LMICs). The relative effectiveness of UCTs compared with conditional cash transfers (CCTs; provided so long as the recipient engages in prescribed behaviours such as using a health service or attending school) is unknown...
November 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29138648/vascular-hyperreactivity-in-black-cameroonian-hypertensive-and-normotensive-patients-a-comparative-study
#15
Sylvie Ndongo Amougou, Dieudonné Danwe, Hamadou Ba, Bonaventure Jemea, Liliane Kuate Mfeukeu, Christian Ngongang Ouankou, Jingi Musa Ahmadou, Samuel Kingue
Introduction: Vascular hyperreactivity is a risk factor and a factor predicting hypertension (high blood pressure). Unlike other continents where several studies were carried out, it has rarely been studied in black Africa in general and in Cameroon in particular. Methods: Vascular reactivity was measured by the cold test. Vascular hyperreactivity was defined as an increase in blood pressure > 20 mmHg for systolic and/or > 15 mmHg for diastolic. Khi(2), Man-Withney, Wilcoxon's signed ranks and logistic regression tests were used for statistical analysis...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29137701/the-correlation-between-atls-and-junior-doctors-anatomical-knowledge-of-central-venous-catheter-insertion-in-trauma-service-in-south-africa
#16
V Y Kong, J J Odendaal, R Weale, M Liu, C M Keene, B Sartorius, D L Clarke
OBJECTIVE: To review the ability of junior doctors (JDs) in identifying the correct anatomical site for central venous catheterization (CVC) and whether prior Advanced Trauma Life Support (ATLS) training influences this. DESIGN: We performed a prospective, observational study using a structured survey and asked a group of JDs (postgraduate year 1 [PGY1] or year 2 [PGY2]) to indicate on a photograph the exact site for CVC insertion via the internal jugular (IJV) and the subclavian (SCV) approach...
November 7, 2017: Injury
https://www.readbyqxmd.com/read/29136032/virological-response-and-resistance-among-hiv-infected-children-receiving-long-term-antiretroviral-therapy-without-virological-monitoring-in-uganda-and-zimbabwe-observational-analyses-within-the-randomised-arrow-trial
#17
Alexander J Szubert, Andrew J Prendergast, Moira J Spyer, Victor Musiime, Philippa Musoke, Mutsa Bwakura-Dangarembizi, Patricia Nahirya-Ntege, Margaret J Thomason, Emmanuel Ndashimye, Immaculate Nkanya, Oscar Senfuma, Boniface Mudenge, Nigel Klein, Diana M Gibb, A Sarah Walker
BACKGROUND: Although WHO recommends viral load (VL) monitoring for those on antiretroviral therapy (ART), availability in low-income countries remains limited. We investigated long-term VL and resistance in HIV-infected children managed without real-time VL monitoring. METHODS AND FINDINGS: In the ARROW factorial trial, 1,206 children initiating ART in Uganda and Zimbabwe between 15 March 2007 and 18 November 2008, aged a median 6 years old, with median CD4% of 12%, were randomised to monitoring with or without 12-weekly CD4 counts and to receive 2 nucleoside reverse transcriptase inhibitors (2NRTI, mainly abacavir+lamivudine) with a non-nucleoside reverse transcriptase inhibitor (NNRTI) or 3 NRTIs as long-term ART...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29136014/treatment-guidelines-and-early-loss-from-care-for-people-living-with-hiv-in-cape-town-south-africa-a-retrospective-cohort-study
#18
Ingrid T Katz, Richard Kaplan, Garrett Fitzmaurice, Dominick Leone, David R Bangsberg, Linda-Gail Bekker, Catherine Orrell
BACKGROUND: South Africa has undergone multiple expansions in antiretroviral therapy (ART) eligibility from an initial CD4+ threshold of ≤200 cells/μl to providing ART for all people living with HIV (PLWH) as of September 2016. We evaluated the association of programmatic changes in ART eligibility with loss from care, both prior to ART initiation and within the first 16 weeks of starting treatment, during a period of programmatic expansion to ART treatment at CD4+ ≤ 350 cells/μl...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29135581/high-rates-of-hypertension-diabetes-elevated-low-density-lipoprotein-cholesterol-and-cardiovascular-disease-risk-factors-in-hiv-infected-patients-results-from-a-cross-sectional-survey-in-malawi
#19
Sekai C Mathabire Rücker, Alia Tayea, Joseph Bitilinyu-Bangoh, Elkin H Bermúdez-Aza, Leon Salumu, Isabel A Quiles, Elisabeth Szumilin, Zengani Chirwa, Fernanda Rick, David Maman
OBJECTIVES: Data on cardiovascular disease risks among HIV-infected patients taking antiretroviral therapy (ART) over long periods of time are lacking in Sub-Saharan Africa. METHODS: A cross-sectional study was conducted in Chiradzulu, Malawi from December 2015 to June 2016. HIV-infected persons on ART for more than 10 years (patients) and HIV-negative individuals (controls) from selected clinics participated. Following informed consent, a standardized questionnaire, clinical and laboratory examinations were performed...
November 10, 2017: AIDS
https://www.readbyqxmd.com/read/29134422/hiv-prevention-among-young-women-in-south-africa-understanding-multiple-layers-of-risk
#20
Christina Psaros, Cecilia Milford, Jennifer A Smit, Letitia Greener, Nzwakie Mosery, Lynn T Matthews, Abigail Harrison, Janna R Gordon, Matthew Mimiaga, David R Bangsberg, Steven A Safren
Despite concerted prevention efforts, young South African women remain at the epicenter of the HIV epidemic. Although these women have grown up in a community powerfully affected by HIV, systematic investigation into how this "second generation" of HIV-affected youth navigates HIV risk is lacking. This study qualitatively explored a complex interplay of factors influencing HIV risk among young pregnant women in KwaZulu-Natal, South Africa. We conducted in-depth interviews with 35 pregnant women (22 HIV-uninfected and 13 HIV-infected) aged 18-21, 18 healthcare providers, and focus groups with 19 community stakeholders...
November 13, 2017: Archives of Sexual Behavior
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