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https://www.readbyqxmd.com/read/29915092/dye-sensitized-photoelectrochemical-water-oxidation-through-a-buried-junction
#1
Pengtao Xu, Tian Huang, Jianbin Huang, Yun Yan, Thomas E Mallouk
Water oxidation has long been a challenge in artificial photosynthetic devices that convert solar energy into fuels. Water-splitting dye-sensitized photoelectrochemical cells (WS-DSPECs) provide a modular approach for integrating light-harvesting molecules with water-oxidation catalysts on metal-oxide electrodes. Despite recent progress in improving the efficiency of these devices by introducing good molecular water-oxidation catalysts, WS-DSPECs have poor stability, owing to the oxidation of molecular components at very positive electrode potentials...
June 18, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29913998/early-maladaptive-schemas-in-finnish-adult-chronic-male-and-female-pain-patients
#2
Tom H J Saariaho, Anita S I Saariaho, Irma A Karila, Matti I Joukamaa
Background and aims of the study The connection between chronic pain and traumatic experiences in childhood has been established in several studies. The association of emotional maltreatment with chronic pain has been studied, but to a lesser degree. Schema therapy [24] is an extension of cognitive therapy and presents the early maladaptive schema (EMS) concept. EMSs reflect early, mainly emotional maltreatment. The aim of the present study was to examine the existence of EMSs, the association between EMSs and pain variables and EMS driven patterns...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912926/nev-supply-chain-coordination-and-sustainability-considering-sales-effort-and-risk-aversion-under-the-cvar-criterion
#3
Shifeng Han, Xingzhong Xu
In a two-echelon new energy vehicle (NEV) supply chain consisting of a risk-neutral manufacturer and a risk-averse retailer, the coordination and sustainability problem is investigated. The risk-averse retailer, who makes sales effort and undertakes the incurred effort cost, decides the order quantity and sales effort level under the Conditional Value-at-Risk (CVaR) criterion. We derive the optimal centralized decisions of a vertically integrated supply chain where the retailer is owned by the manufacturer...
2018: PloS One
https://www.readbyqxmd.com/read/29909962/squalene-synthase-deficiency-clinical-biochemical-and-molecular-characterization-of-a-defect-in-cholesterol-biosynthesis
#4
David Coman, Lisenka E L M Vissers, Lisa G Riley, Michael P Kwint, Roxanna Hauck, Janet Koster, Sinje Geuer, Sarah Hopkins, Barbra Hallinan, Larry Sweetman, Udo F H Engelke, T Andrew Burrow, John Cardinal, James McGill, Anita Inwood, Christine Gurnsey, Hans R Waterham, John Christodoulou, Ron A Wevers, James Pitt
Mendelian disorders of cholesterol biosynthesis typically result in multi-system clinical phenotypes, underlining the importance of cholesterol in embryogenesis and development. FDFT1 encodes for an evolutionarily conserved enzyme, squalene synthase (SS, farnesyl-pyrophosphate farnesyl-transferase 1), which catalyzes the first committed step in cholesterol biosynthesis. We report three individuals with profound developmental delay, brain abnormalities, 2-3 syndactyly of the toes, and facial dysmorphisms, resembling Smith-Lemli-Opitz syndrome, the most common cholesterol biogenesis defect...
June 1, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29909552/early-outcomes-of-270-degree-spinal-canal-decompression-by-using-tessys-isee-technique-in-patients-with-lumbar-spinal-stenosis-combined-with-disk-herniation
#5
Chengjie Xiong, Tao Li, Hui Kang, Hao Hu, Jing Han, Feng Xu
PURPOSE: Traditional open approach is an efficient way to treat lumbar spinal stenosis (SS) combined with disk herniation (DH); however, risk factors such as advanced age, osteoporosis etc. are associated with the complications after the surgery. This study aims to analyze the early clinical and radiological outcomes of treatment on SS&DH by using newly developed minimal invasive TESSYS-ISEE technique. METHODS: Patients with limp and unilateral lower limb radiculopathy underwent minimal invasive surgery by using TESSYS-ISEE technique...
June 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29909519/growth-performance-and-plasma-metabolites-in-juvenile-siberian-sturgeon-acipenser-baerii-brandt-1869-subjected-to-various-feeding-strategies-at-different-sizes
#6
Naghmeh Jafari, Bahram Falahatkar, Mir Masoud Sajjadi
The effect of various feeding strategies was evaluated on growth performance and biochemical parameters in two sizes of Siberian sturgeon (465.75 ± 11.18 and 250.40 ± 12 g) during 45 days. Fish were distributed into six experimental treatments including large fish with satiation feeding (LA), small fish with satiation feeding (SA), large fish with 50% satiation feeding (LR), small fish with 50% satiation feeding (SR), large starved fish (LS), and small starved fish (SS). Differences in final weight between LA and LR treatments were not noticeable, whereas SA and SR treatments showed significant differences...
June 16, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29908893/post-pegylated-and-crosslinked-polymeric-ssrna-nanocomplexes-as-adjuvants-targeting-lymph-nodes-with-increased-cytolytic-t-cell-inducing-properties
#7
Bo Lou, Ans De Beuckelaer, George R Dakwar, Katrien Remaut, Johan Grooten, Kevin Braeckmans, Bruno G De Geest, Enrico Mastrobattista, Stefaan De Koker, Wim E Hennink
Potent adjuvants are highly demanded for most protein and peptides based vaccine candidates in clinical development. Recognition of viral single stranded (ss)RNA by innate toll-like receptors 7/8 in dendritic cells results in a cytokine environment supportive to the establishment of long lasting antibody responses and Th1 oriented T cell immunity. To fully exploit the immunestimulatory properties of ssRNA, it needs to be adequately formulated to ensure its optimal delivery to dendritic cells in the vaccine draining lymph nodes...
June 14, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29907907/three-novel-mutations-in-20-patients-with-hereditary-spastic-paraparesis
#8
Mehmet Bugrahan Duz, Selcuk Dasdemir, Aysel Kalayci Yigin, Mehmet Ali Akalin, Mehmet Seven
Hereditary spastic paraparesis (HSP) constitutes both genetic and clinically heterogeneous group of upper motor neuron diseases. Half of the individuals with autosomal dominant (AD) HSP have mutations in SPAST, ATL1, and REEP1 genes. This study was conducted to elucidate the genetic etiology of patients with the pure type AD-HSP diagnosis. The patient group consisted of 23 individuals from 6 families in Turkey. In the first step of work, Sanger sequencing (SS) was performed in ATL1, SPAST, and REEP1 genes and the second phase whole-exome sequencing (WES) was performed following SS analysis for the patients with no detected mutations in these genes...
June 16, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29907191/molecular-characterization-and-allergenicity-potential-of-triosephosphate-isomerase-from-sarcoptes-scabiei
#9
Ran He, Haojie Zhang, Nengxing Shen, Cheng Guo, Yongjun Ren, Yue Xie, Xiaobin Gu, Weimin Lai, Xuerong Peng, Guangyou Yang
Scabies is an allergic skin disease that affects millions of mammals worldwide, including humans. It is a neglected tropical disease that represents a significant public health threat, particularly in economically disadvantaged populations. An effective vaccine is not currently available, and the exact mode of pathogenesis remains unclear. Herein, we identified, cloned and recombinantly expressed triosephosphate isomerase from Sarcoptes scabiei (S. scabiei). Immunohistochemical analyses showed that S. scabiei triosephosphate isomerase (Ss-TIM) is localized in the legs and chewing mouthparts of mites, and in infected rabbit skin (keratinized skin and embedded mites)...
June 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29903885/dirac-source-field-effect-transistors-as-energy-efficient-high-performance-electronic-switches
#10
Chenguang Qiu, Fei Liu, Lin Xu, Bing Deng, Mengmeng Xiao, Jia Si, Li Lin, Zhiyong Zhang, Jian Wang, Hong Guo, Hailin Peng, Lian-Mao Peng
An efficient way to reduce the power is to lower the supply voltage VDD , but this voltage is restricted by the 60 millivolts per decade thermionic limit of subthreshold swing (SS) in field-effect transistors (FETs). We show that a graphene Dirac source (DS) with a much narrower electron density distribution around the Fermi level than that of conventional FETs can lower SS. A DS-FET with a carbon nanotube channel provided an average SS of 40 millivolt per decade over four decades of current at room temperature and high device current I60 of up to 40 microampere per micrometer at 60 millivolts per decade...
June 14, 2018: Science
https://www.readbyqxmd.com/read/29903675/effect-of-hydraulic-retention-time-on-nitrogen-removal-and-functional-gene-quantity-transcription-in-biochar-packed-reactors-at-5-%C3%A2-c-a-control-strategy-study
#11
Su He, Lili Ding, Yao Pan, Haidong Hu, Lin Ye, Hongqiang Ren
This study investigated the effect of hydraulic retention time (HRT = 8, 12, 16, and 24 h) on effluent dissolved organic nitrogen (DON), dissolved total nitrogen (DTN), and functional gene quantity/transcription in biochar packed reactors over a 125-day operation at 5 °C. The lowest effluent DON concentration (0.21 ± 0.14 mg/L) and DTN concentration (10.74 ± 0.41 mg/L) were in R12h and R24h , respectively. Adequate HRT (>12 h) was a necessary parameter for poly-β-hydroxybutyrate (PHB) accumulation (PHB/MLSS: 0...
June 6, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29903487/improved-lung-nodule-diagnosis-accuracy-using-lung-ct-images-with-uncertain-class
#12
Zhiqiong Wang, Junchang Xin, Peishun Sun, Zhixiang Lin, Yudong Yao, Xiaosong Gao
BACKGROUND AND OBJECTIVE: Among all malignant tumors, lung cancer ranks in the top in mortality rate. Pulmonary nodule is the early manifestation of lung cancer, and plays an important role in its discovery, diagnosis and treatment. The technology of medical imaging has encountered a rapid development in recent years, thus the amount of pulmonary nodules can be discovered are on the raise, which means even tiny or minor changes in lung can be recorded by the CT images. This paper proposes a pulmonary nodule computer aided diagnosis (CAD) based on semi-supervised extreme learning machine(SS-ELM)...
August 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29903023/combining-sense-and-reduced-field-of-view-for-high-resolution-diffusion-weighted-magnetic-resonance-imaging
#13
Jisu Hu, Ming Li, Yakang Dai, Chen Geng, Baotong Tong, Zhiyong Zhou, Xue Liang, Wen Yang, Bing Zhang
BACKGROUND: In diffusion-weighted magnetic resonance imaging (DWI) using single-shot echo planar imaging (ss-EPI), both reduced field-of-view (FOV) excitation and sensitivity encoding (SENSE) alone can increase in-plane resolution to some degree. However, when the two techniques are combined to further increase resolution without pronounced geometric distortion, the resulted images are often corrupted by high level of noise and artifact due to the numerical restriction in SENSE. Hence, this study is aimed to provide a reconstruction method to deal with this problem...
June 15, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29902805/evidence-for-the-detection-of-subclinical-retinal-involvement-in-systemic-lupus-erythematosus-and-sj%C3%A3-gren-syndrome-a-potential-association-with-therapies
#14
Paola Conigliaro, Paola Triggianese, Gianluca Draghessi, Claudia Canofari, Gianluca Aloe, Maria Sole Chimenti, Claudia Valeri, Carlo Nucci, Roberto Perricone, Massimo Cesareo
BACKGROUND: Retinal involvement in systemic lupus erythematosus (SLE) and Sjögren syndrome (SS) may be subclinical and thus underdiagnosed. OBJECTIVES: We aimed at evaluating morphological and functional visual abnormalities in a cohort of SLE and SS patients in the absence of an overt clinical visual impairment. We also investigated potential associations between retinal disorders and disease activity, organ involvement, and treatment with steroid and/or hydroxychloroquine...
June 14, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29902673/revealing-the-molecular-interactions-of-aptamers-that-specifically-bind-to-the-extracellular-domain-of-her2-cancer-biomarker-protein-an-in-silico-assessment
#15
Sarfaraj Niazi, Madhusudan Purohit, Archana Sonawani, Javed H Niazi
Single-stranded (ss) oligonucleotide aptamers are emerging as the promising substitutes for monoclonal antibodies because of their low production cost and good batch-to-batch consistency. Aptamers vividly bind to a variety of cellular targets and alter their functions with a remarkable degree of specificities. In this study, the positive clones of human epidermal growth factor receptor 2 (HER2) specific binding ssDNA aptamers which were previously identified by in vitro Systematic Evolution of Ligands by EXponential enrichment (SELEX) process, hitherto lacking the putative binding site information and residues crucial for aptamer recognition are studied...
June 6, 2018: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/29902532/mussel-inspired-catalytic-selenocystamine-dopamine-coatings-for-long-term-generation-of-therapeutic-gas-on-cardiovascular-stents
#16
Zhilu Yang, Ying Yang, Li Zhang, Kaiqin Xiong, Xiangyang Li, Feng Zhang, Jin Wang, Xin Zhao, Nan Huang
The development of a nitric oxide (NO)-generating surface with long-term, stable and controllable NO release improves the therapeutic efficacy of cardiovascular stents. In this work, we developed a "one-pot" method inspired by mussel adhesive proteins for copolymerization of selenocystamine (SeCA) and dopamine (Dopa) to form a NO-generating coating on a 316 L stainless steel (SS) stent. This "one-pot" method is environmentally friendly and easy to popularize, with many advantages including simple manufacturing procedure, high stability and no involvement of organic solvents...
June 7, 2018: Biomaterials
https://www.readbyqxmd.com/read/29901770/serotonin-syndrome-in-obstetrics-a-case-report-and-review-of-management
#17
Capt Heisy B Asusta, Maj Erin Keyser, Patricia Dominguez, Marvin Miller
Serotonin syndrome (SS) is a life-threatening condition, usually precipitated by a combination of serotonergic agents. Data regarding the incidence and management of SS in obstetrics are limited. This study presents a case of SS provoked by an atypical antipsychotic in a second trimester, singleton gestation, and reviews the management of SS in an obstetric patient. We present a case of a schizophreniform, pregnant patient with a singleton gestation admitted to a community, military hospital for serotonin syndrome...
June 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29900998/beta-2-microglobulin-in-whole-unstimulated-saliva-can-effectively-distinguish-between-sj%C3%A3-gren-s-syndrome-and-non-autoimmune-sicca-symptoms
#18
Janett Riega-Torres, Guillermo Delgado-García, Julio César Salas-Alanís, Cassandra Skinner-Taylor, Lorena Pérez-Barbosa, Mario Garza-Elizondo, Celia Nohemí Sánchez-Domínguez, Luis Ángel Ceceñas-Falcón, Karim Mohamed-Noriega, Jesús Mohamed-Hamsho, David Vega-Morales
Objectives: This study aims to describe salivary beta-2 microglobulin (sB2M) levels in our setting and to assess the performance of sB2M for the diagnosis of Sjögren's syndrome (SS). Patients and methods: This cross-sectional, comparative study included 192 SS patients (2 males, 190 females; mean age 53.1 years; range 23 to 84 years) and 64 healthy controls (1 male, 63 females; mean age 46.9 years; range 21 to 82 years). Patients were divided into three groups as those with primary SS, secondary SS, and sicca non-Sjögren's syndrome (snSS)...
December 2017: Archives of Rheumatology
https://www.readbyqxmd.com/read/29900900/erythema-nodosum-leprosum-presenting-as-sweet-s-syndrome-like-reaction-in-a-borderline-lepromatous-leprosy-patient
#19
Nyoman Suryawati, Herman Saputra
Erythema nodosum leprosum (ENL) is characterized by tender erythematous nodules, accompanied by fever, malaise, arthralgia, and systemic complications. Atypical clinical manifestations have been reported such as pustular, bullous, ulceration; livedo reticularis; erythema multiforme-like reaction; and Sweet's syndrome (SS)-like presentation. We reported a case of ENL reaction presenting as SS-like reaction in a borderline lepromatous leprosy patient.
April 2018: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/29900259/evaluation-and-comparison-the-performance-of-titanium-and-zirconium-iv-tetrachloride-in-textile-wastewater-treatment
#20
Hamidi Abdul Aziz, Muhamad Haziq Abd Razak, Muhammad Zamir Abdul Rahim, Wan Izatul Saadiah Wan Kamar, Salem S Abu Amr, Sabir Hussain, John Van Leeuwen
Wastewater treatment is a key challenge in the textile industry. The current treatment methods for textile wastewater are insufficient or ineffective for complex dyes generated from the textile industry. This study evaluated the performances of two novel inorganic coagulants with high cationic charges, namely, titanium tetrachloride (TiCl4 ) and zirconium tetrachloride (ZrCl4 ). They were utilised to treat textile industry wastewater. Both coagulation processes were performed under the same experimental operational conditions...
June 2018: Data in Brief
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