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https://www.readbyqxmd.com/read/29470448/the-spectrum-analysis-solution-sas-system-theoretical-analysis-hardware-design-and-implementation
#1
Ram M Narayanan, Richard K Pooler, Anthony F Martone, Kyle A Gallagher, Kelly D Sherbondy
This paper describes a multichannel super-heterodyne signal analyzer, called the Spectrum Analysis Solution (SAS), which performs multi-purpose spectrum sensing to support spectrally adaptive and cognitive radar applications. The SAS operates from ultrahigh frequency (UHF) to the S-band and features a wideband channel with eight narrowband channels. The wideband channel acts as a monitoring channel that can be used to tune the instantaneous band of the narrowband channels to areas of interest in the spectrum...
February 22, 2018: Sensors
https://www.readbyqxmd.com/read/29470429/belowground-interactions-impact-the-soil-bacterial-community-soil-fertility-and-crop-yield-in-maize-peanut-intercropping-systems
#2
Qisong Li, Jun Chen, Linkun Wu, Xiaomian Luo, Na Li, Yasir Arafat, Sheng Lin, Wenxiong Lin
Intercropping has been widely used to control disease and improve yield in agriculture. In this study, maize and peanut were used for non-separation intercropping (NS), semi-separation intercropping (SS) using a nylon net, and complete separation intercropping (CS) using a plastic sheet. In field experiments, two-year land equivalent ratios (LERs) showed yield advantages due to belowground interactions when using NS and SS patterns as compared to monoculture. In contrast, intercropping without belowground interactions (CS) showed a yield disadvantage...
February 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29469223/mitoprotective-therapy-preserves-chondrocyte-viability-and-prevents-cartilage-degeneration-in-an-ex-vivo-model-of-posttraumatic-osteoarthritis
#3
Michelle L Delco, Edward D Bonnevie, Hazel S Szeto, Lawrence J Bonassar, Lisa A Fortier
No disease-modifying osteoarthritis (OA) drugs are available to prevent posttraumatic osteoarthritis (PTOA). Mitochondria (MT) mediate the pathogenesis of many degenerative diseases, and recent evidence indicates that MT dysfunction is a peracute (within minutes to hours) response of cartilage to mechanical injury. The goal of this study was to investigate cardiolipin-targeted mitoprotection as a new strategy to prevent chondrocyte death and cartilage degeneration after injury. Cartilage was harvested from bovine knee joints and subjected to a single, rapid impact injury (24...
February 22, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29468745/promises-challenges-and-recent-progress-of-inorganic-solid-state-electrolytes-for-all-solid-state-lithium-batteries
#4
REVIEW
Zhonghui Gao, Huabin Sun, Lin Fu, Fangliang Ye, Yi Zhang, Wei Luo, Yunhui Huang
All-solid-state lithium batteries (ASSLBs) have the potential to revolutionize battery systems for electric vehicles due to their benefits in safety, energy density, packaging, and operable temperature range. As the key component in ASSLBs, inorganic lithium-ion-based solid-state electrolytes (SSEs) have attracted great interest, and advances in SSEs are vital to deliver the promise of ASSLBs. Herein, a survey of emerging SSEs is presented, and ion-transport mechanisms are briefly discussed. Techniques for increasing the ionic conductivity of SSEs, including substitution and mechanical strain treatment, are highlighted...
February 22, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29468393/growth-performance-metal-accumulation-and-biochemical-responses-of-palak-beta-vulgaris-l-var-allgreen-h-1-grown-on-soil-amended-with-sewage-sludge-fly-ash-mixtures
#5
Bhavisha Sharma, Richa Kothari, Rajeev Pratap Singh
Agricultural utilization of sewage sludge (SS) and fly ash (FA) has become both, a common practice and an alternative disposal method for these wastes all around the world. The present study was conducted to assess the effect and viability of co-application of SS and FA (SLASH) in four mixing ratios denoted as A [4 (SS): 1(FA)], B [4 (SS): 2 (FA)], C [4 (SS): 3 (FA)] and D [4 (SS): 4(FA)] at three application rates viz. 20, 40 and 60% (w/w) with agricultural soil on biochemical, physiological and growth response of Palak (Beta vulgaris L...
February 21, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29467695/returning-to-work-after-childbirth-in-europe-well-being-work-life-balance-and-the-interplay-of-supervisor-support
#6
Ana M Lucia-Casademunt, Antonia M García-Cabrera, Laura Padilla-Angulo, Deybbi Cuéllar-Molina
Parents returning to work after the arrival of a new son or daughter is an important question for understanding the trajectory of people's lives and professional careers amid current debates about gender equality and work-life balance (WLB). Interestingly, current research concludes that general WLB practices at the workplace may be necessary in the specific case of women returning to work after childbirth because of the particular maternal and infant factors involved. However, WLB practices as a flexible arrangement may work against women because they may be viewed as a lack of organizational commitment...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29466794/foxo1-a-potential-therapeutic-target-regulates-autophagic-flux-oxidative-stress-mitochondrial-dysfunction-and-apoptosis-in-human-cholangiocarcinoma-qbc939-cells
#7
Wei He, Aiqing Zhang, Lei Qi, Chen Na, Rui Jiang, Zhining Fan, Jianping Chen
BACKGROUND/AIMS: Autophagy is an evolutionarily conserved catabolic mechanism to maintain energy homeostasis and to remove damaged cellular components, which plays an important role in the survival of various cells. Inhibiting autophagy is often applied as a new strategy to halt the growth of cancer cells. METHODS: The effect of FOXO1 gene on cellular function and apoptosis and its underlying mechanisms were investigated in cultured QBC939 cells by the methylthiazoletetrazolium (MTT) assay, western blot, DCFDA mitochondrial membrane potential, and ATP content measurement...
February 16, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29466710/low-shear-stress-induces-vascular-enos-uncoupling-via-autophagy-mediated-enos-phosphorylation
#8
Jun-Xia Zhang, Xin-Liang Qu, Peng Chu, Du-Jiang Xie, Lin-Lin Zhu, Yue-Lin Chao, Li Li, Jun-Jie Zhang, Shao-Liang Chen
Uncoupled endothelial nitric oxide synthase (eNOS) produces O2 - instead of nitric oxide (NO). Earlier, we reported rapamycin, an autophagy inducer and inhibitor of cellular proliferation, attenuated low shear stress (SS) induced O2 - production. Nevertheless, it is unclear whether autophagy plays a critical role in the regulation of eNOS uncoupling. Therefore, this study aimed to investigate the modulation of autophagy on eNOS uncoupling induced by low SS exposure. We found that low SS induced endothelial O2 - burst, which was accompanied by reduced NO release...
February 18, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29465536/primary-cutaneous-amyloidosis-associated-with-autoimmune-hepatitis-primary-biliary-cirrhosis-overlap-syndrome-and-sj%C3%A3-gren-syndrome-a-case-report
#9
Xin Yan, Jinglan Jin
RATIONALE: Primary cutaneous amyloidosis (PCA) is a localized skin disorder characterized by the abnormal deposition of amyloid in the extracellular matrix of the dermis. The association between PCA and other diseases, although rare, has been documented for various autoimmune diseases. PCA associated with autoimmune hepatitis-primary biliary cirrhosis (AIH-PBC) overlap syndrome and Sjögren syndrome (SS) has not been previously reported in the literature. PATIENT CONCERNS: A 50-year-old woman presented with progressive abnormal liver enzyme levels and was referred to our department...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29464796/drug-like-dietary-vanilloids-induce-anticancer-activity-through-proliferation-inhibition-and-regulation-of-bcl-related-apoptotic-proteins
#10
Chun-Wai Mai, Yew-Beng Kang, Vishna Devi Nadarajah, Ahmad Sazali Hamzah, Mallikarjuna Rao Pichika
In this study, a series of 20 structurally similar vanilloids (Vn) were tested for their antiproliferative effects against 12 human cancer cells: human breast (MCF-7 and MDA-MB-231), cervical (HeLa), ovarian (Caov-3), lung (A549), liver (HepG2), colorectal (HT-29 and HCT116), nasopharyngeal (CNE-1 and HK-1), and leukemic (K562 and CEM-SS) cancer cells. Among all the tested vanilloids, Vn16 (6-shogaol) exhibited the most potent cytotoxic effects against human colorectal cancer cells (HT-29). The apoptotic induction effects exhibited by Vn16 on HT-29 cells were confirmed using dual staining fluorescence microscopy and enzyme-linked immunosorbent assay...
February 21, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29464357/decreased-bone-mineral-density-in-women-with-sheehan-s-syndrome-and-improvement-following-oestrogen-replacement-and-nutritional-supplementation
#11
Purnima Agarwal, Ramesh Gomez, Eesh Bhatia, Subhash Yadav
Sheehan's syndrome (SS) is an important cause of pan-hypopituitarism in women. There is scanty information on bone mineral density (BMD) in this condition. We determined BMD and the changes in BMD after oestrogen (E2) replacement and nutritional supplementation in women with SS. In a cross-sectional study, BMD was measured by DEXA in 83 patients [age (mean ± SD) 42 ± 9.2 years] and compared with an equal number of matched controls. In a sub-set of 19 patients, we conducted an open-label, prospective study to determine changes in BMD after 1 year of replacement of E2, and calcium and vitamin D3 supplementation...
February 20, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29463848/autoantibodies-against-the-immunoglobulin-binding-region-of-ro52-link-its-autoantigenicity-with-pathogen-neutralization
#12
Peter D Burbelo, Leyla Y Teos, Jesse L Herche, Michael J Iadarola, Ilias Alevizos
Ro52/TRIM21 plays a key role in antibody-dependent pathogen neutralization and is a major autoantigen in systemic lupus erythematosus, Sjögren's syndrome (SS), and other autoimmune diseases. Here we evaluated immunoreactivity against Ro52-related molecules in SS and healthy volunteers. Although most proteins examined were not antigenic, several TRIM paralogs, including TRIM22, and TRIM38, showed sporadic immunoreactivity in SS. In contrast, the murine Ro52 ortholog with limited linear homology demonstrated high levels of autoantibodies implicating the importance of shared conformational epitopes...
February 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29463076/acute-pituitary-disease-in-pregnancy-how-to-handle-hypophysitis-and-sheehan-s-syndrome
#13
Jürgen Honegger, Sabrina Giese
Pregnancy-related hypophysitis (PR-Hy) that typically occurs during late pregnancy and the early postpartum period is considered an autoimmune disorder. Knowledge and awareness of characteristic clinical symptoms and specific endocrine and neuroradiological features mostly enables a correct diagnosis and guarantees best possible management. In the presence of mild clinical symptoms, a "wait and watch" policy is recommended. Transsphenoidal surgery or glucocorticoid therapy is indicated if progressive clinical signs or severe visual symptoms are observed...
February 19, 2018: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29462807/the-return-of-fear-variation-of-the-serotonin-transporter-gene-predicts-outcome-of-a-highly-standardized-exposure-based-one-session-fear-treatment
#14
André Wannemüller, Dirk Moser, Robert Kumsta, Hans-Peter Jöhren, Jürgen Margraf
BACKGROUND: Methodological problems of existing research, such as the application of unstandardized treatments in heterogeneous samples, has hampered clear conclusions about the extent and direction to which allelic variation of the serotonin transporter gene-linked polymorphic region (5- HTTLPR) is associated with a differential response to psychological treatment. The present study aimed to investigate the effects of the 5-HTTLPR genotype on treatment outcome under highly standardized environmental conditions...
February 21, 2018: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/29462129/family-history-of-cancer-and-the-risk-of-childhood-solid-tumours-a-norwegian-nationwide-register-based-cohort-study
#15
Ruby Del Risco Kollerud, Karl Gerhard Blaasaas, Bjørgulf Claussen, Per Nafstad, Lisa A Cannon-Albright, Ellen Ruud, Finn Wesenberg, Øyvind Næss
BACKGROUND: It is not clear if family history of cancer increases risk of cancer in children. METHODS: We followed-up a total of 2 610 937 children born between 1960 and 2001 for cancer risk, and their parents and siblings. In this period, 2477 primary childhood solid tumours (except lymphoma) were diagnosed. The data from the Norwegian Family and Life Course Study and from the Norwegian Cancer Register were used. Classification of hereditary cancer syndromes was based on tumour histology, pedigrees and Chompret's criteria...
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29461920/a-randomized-controlled-trial-for-veterans-with-ptsd-and-substance-use-disorder-creating-change-versus-seeking-safety
#16
Lisa M Najavits, Karen Krinsley, Molly E Waring, Matthew W Gallagher, Christopher Skidmore
BACKGROUND: Posttraumatic stress disorder (PTSD) and substance use disorder (SUD) co-occur in military veterans and other populations. OBJECTIVE: To conduct a randomized controlled trial to compare a new past-focused treatment (Creating Change; CC), to a well-established, evidence-based present-focused treatment for PTSD/SUD (Seeking Safety; SS), on symptoms of both disorders. CC guides patients to process the past through exploration of PTSD/SUD life themes and memories whereas SS focuses on coping skills in the present...
February 20, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29461341/influence-of-the-initial-sagittal-lumbar-alignment-on-clinical-and-radiological-outcomes-of-single-level-lumbar-total-disc-replacements-at-a-minimum-two-year-follow-up
#17
Aymeric Faure, Marc Khalifé, Benjamin Thiebaut, François Roubineau, Charles Henri Flouzat Lachaniette, Arnaud Dubory
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To analyze the clinical and radiographic outcomes of patients undergoing a one-level lumbar total disc replacement (TDR), according to the initial sagittal alignment of the spine. SUMMARY OF BACKGROUND DATA: No authors have highlighted correlation between the initial spino-pelvic parameters and the postoperative outcome after a one-level TDR. METHODS: Seventy-eight patients were included: 14 TDR at L4-L5 and 64 TDR at L5-S1 level...
February 15, 2018: Spine
https://www.readbyqxmd.com/read/29460700/the-lupus-patient-with-positive-rheumatoid-factor
#18
A Fedrigo, T A F G Dos Santos, R Nisihara, T Skare
Background Patients with systemic lupus erythematosus (SLE) may form clusters with clinical manifestations and autoantibodies. Objective The objective of this report is to study whether SLE patients with positive rheumatoid factor (RF) have a special clinical and/or serological profile. Methods A retrospective study of 467 SLE patients seen at a single rheumatology unit was conducted. Epidemiological data (age, gender, age at disease onset, ethnic background and tobacco use), clinical data (malar rash, photosensitivity, oral ulcers, discoid lesions, serositis, glomerulonephritis, convulsions, psychosis, hemolytic anemia, leukopenia, lymphocytopenia, arthritis and hypothyroidism) and serological profile (anti-dsDNA, anti-Ro/SS-A, anti-La/SS-B, anti-RNP, anti-Sm, IgG aCL, IgM aCL, lupus anticoagulant, direct Coombs and RF) were collected...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29460694/control-of-exposure-to-hexavalent-chromium-concentration-in-shielded-metal-arc-welding-fumes-by-nano-coating-of-electrodes
#19
S P Sivapirakasam, Sreejith Mohan, M C Santhosh Kumar, Ashley Thomas Paul, M Surianarayanan
Background Cr(VI) is a suspected human carcinogen formed as a by-product of stainless steel welding. Nano-alumina and nano-titania coating of electrodes reduced the welding fume levels. Objective To investigate the effect of nano-coating of welding electrodes on Cr(VI) formation rate (Cr(VI) FR) from a shielded metal arc welding process. Methods The core welding wires were coated with nano-alumina and nano-titania using the sol-gel dip coating technique. Bead-on plate welds were deposited on SS 316 LN plates kept inside a fume test chamber...
February 20, 2018: International Journal of Occupational and Environmental Health
https://www.readbyqxmd.com/read/29460018/observation-of-neovascularization-of-the-disc-associated-with-proliferative-diabetic-retinopathy-using-oct-angiography
#20
Hideo Akiyama, Danjie Li, Yukitoshi Shimoda, Hidetaka Matsumoto, Shoji Kishi
PURPOSE: To describe the relationship between the vitreous and the neovascularization of the disc (NVD) using swept source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). STUDY DESIGN: Retrospective. METHODS: We examined 17 eyes of 11 consecutive patients diagnosed as NVD associated with proliferative diabetic retinopathy (PDR). The location of the NVD feeder or collector vessels were examined by using RTVue XR Avanti. To determine the condition of the posterior vitreous detachment (PVD) and the proliferative tissue of the NVD, we performed 12 mm horizontal and vertical scans through the disc using SS-OCT...
February 19, 2018: Japanese Journal of Ophthalmology
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