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https://www.readbyqxmd.com/read/28081044/evaluation-of-the-condom-barriers-scale-for-young-black-men-who-have-sex-with-men-reliability-and-validity-of-3-subscales
#1
Richard A Crosby, Stephanie A Sanders, Cynthia A Graham, Robin Milhausen, William L Yarber, Leandro Mena
BACKGROUND: Reliable and valid scale measures of barriers to condom use are not available for young black men who have sex with men (YBMSM). The purpose of this study was to evaluate the Condom Barriers Scales for application with YBMSM. METHODS: A clinic-based sample of 600 YBMSM completed a computer-assisted self-interview. The primary measure was a 14-item abbreviated version of the Condom Barriers Scale. Reliability and criterion validity were assessed. RESULTS: All 3 subscales were reliable: partner-related barriers (Cronbach α=0...
February 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28072668/genital-and-extragenital-gonorrhea-and-chlamydia-in-children-and-adolescents-evaluated-for-sexual-abuse
#2
Nancy D Kellogg, John D Melville, James L Lukefahr, Shalon M Nienow, Edward L Russell
OBJECTIVE: The aim of this study was to describe the use of a nucleic acid amplification test in detecting genital and extragenital Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) in children and adolescents assessed for sexual abuse/assault. METHODS: The charts of children aged 0 to 17 years, consecutively evaluated for sexual victimization, in emergency department and outpatient settings were reviewed. Data extracted included age, sex, type of sexual contact, anogenital findings, previous sexual contact, toxicology results, and sites tested for NG and CT...
January 9, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28068238/hematologic-nadirs-during-chemoradiation-for-anal-cancer-temporal-characterization-and-dosimetric-predictors
#3
Andrew Y Lee, Daniel W Golden, Jose G Bazan, Malgorzata Kopec, Charles A Pelizzari, Sonya Aggarwal, Daniel T Chang, Stanley L Liauw
PURPOSE: Pelvic bone marrow (BM) constraints may offer a means to reduce the toxicity commonly associated with chemoradiation for anal cancer. We conducted a bi-institutional analysis of dose-volume metrics in a time-sensitive fashion to devise practical metrics to minimize hematologic toxicity. METHODS AND MATERIALS: Fifty-six anal cancer patients from 2 institutions received definitive radiation therapy (median primary dose of 54 Gy) using intensity modulated radiation therapy (IMRT, n=49) or 3-dimensional (3D) conformal therapy (n=7) with concurrent 5-fluorouracil (5-FU) and mitomycin C...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28068178/cetuximab-plus-chemoradiotherapy-in-immunocompetent-patients-with-anal-carcinoma-a-phase-ii-eastern-cooperative-oncology-group-american-college-of-radiology-imaging-network-cancer-research-group-trial-e3205
#4
Madhur K Garg, Fengmin Zhao, Joseph A Sparano, Joel Palefsky, Richard Whittington, Edith P Mitchell, Mary F Mulcahy, Karin I Armstrong, Nassim H Nabbout, Shalom Kalnicki, Bassel F El-Rayes, Adedayo A Onitilo, Daniel J Moriarty, Thomas J Fitzgerald, Al B Benson
Purpose Squamous cell carcinoma of the anal canal (SCCAC) is characterized by high locoregional failure (LRF) rates after sphincter-preserving definitive chemoradiation (CRT) and is typically associated with anogenital human papilloma virus infection. Because cetuximab enhances the effect of radiation therapy in human papilloma virus-associated oropharyngeal squamous cell carcinoma, we hypothesized that adding cetuximab to CRT would reduce LRF in SCCAC. Methods Sixty-one patients with stage I to III SCCAC received CRT including cisplatin, fluorouracil, and radiation therapy to the primary tumor and regional lymph nodes (45 to 54 Gy) plus eight once-weekly doses of concurrent cetuximab...
January 9, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28062389/internet-based-hiv-prevention-with-at-home-sexually-transmitted-infection-testing-for-young-men-having-sex-with-men-study-protocol-of-a-randomized-controlled-trial-of-keep-it-up-2-0
#5
Brian Mustanski, Krystal Madkins, George J Greene, Jeffrey T Parsons, Brent A Johnson, Patrick Sullivan, Michael Bass, Rebekah Abel
BACKGROUND: Human immunodeficiency virus (HIV) infections are increasing among young men who have sex with men (YMSM), yet few HIV prevention programs have studied this population. Keep It Up! (KIU!), an online HIV prevention program tailored to diverse YMSM, was developed to fill this gap. The KIU! 2.0 randomized controlled trial (RCT) was launched to establish intervention efficacy. OBJECTIVE: The objective of the KIU! study is to advance scientific knowledge of technology-based behavioral HIV prevention, as well as improve public health by establishing the efficacy of an innovative electronic health (eHealth) prevention program for ethnically and racially diverse YMSM...
January 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28062314/sexually-acquired-zika-virus-a-systematic-review
#6
REVIEW
José Moreira, Thiago M Peixoto, André Machado de Siqueira, Cristiane C Lamas
BACKGROUND: Zika virus (ZIKV) is transmitted to humans primarily by Aedes mosquito bites. However, circumstantial evidence points to a sexual transmission route. OBJECTIVES: To assess the sexually-acquired ZIKV cases and to investigate the shedding of ZIKV in genital fluids. DATA SOURCES: PubMed, Scopus, Pro-MED-mail, and WHO ZIKV notification databases from inception to December 2016. SELECTION CRITERIA: Reports describing ZIKV acquisition through sex and studies reporting the detection or isolation of ZIKV in the genital fluids were included...
January 3, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28061819/association-between-a-syndemic-of-psychosocial-problems-and-unprotected-anal-intercourse-among-men-who-have-sex-with-men-in-shanghai-china
#7
Ying Wang, Zezhou Wang, Mengmeng Jia, Ajuan Liang, Dong Yuan, Zhe Sun, Feng Gan, Yichen Wang, Yong Cai, Zhiruo Zhang
BACKGROUND: Previous studies have discussed the overlapping and reinforcing effects (defined as a syndemic) of psychosocial problems on high-risk sexual behaviors among men who have sex with men (MSM). The present study aimed to apply the syndemic theory to verify the reinforcing effects of psychosocial problems on unprotected anal intercourse (UAI) among MSM in Shanghai, and determine if other important psychosocial factors fit into the syndemic theory. METHODS: Data were collected from 547 MSM in Shanghai, China, through face-to-face interviews...
January 7, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28060881/individual-hiv-risk-versus-population-impact-of-risk-compensation-after-hiv-preexposure-prophylaxis-initiation-among-men-who-have-sex-with-men
#8
Samuel M Jenness, Akshay Sharma, Steven M Goodreau, Eli S Rosenberg, Kevin M Weiss, Karen W Hoover, Dawn K Smith, Patrick Sullivan
OBJECTIVES: Risk compensation (RC) could reduce or offset the biological prevention benefits of HIV preexposure prophylaxis (PrEP) among those at substantial risk of infection, including men who have sex with men (MSM). We investigated the potential extent and causal mechanisms through which RC could impact HIV transmission at the population and individual levels. METHODS: Using a stochastic network-based mathematical model of HIV transmission dynamics among MSM in the United States, we simulated RC as a reduction in the probability of condom use after initiating PrEP, with heterogeneity by PrEP adherence profiles and partnership type in which RC occurred...
2017: PloS One
https://www.readbyqxmd.com/read/28058564/contribution-of-anal-sex-to-hiv-prevalence-among-heterosexuals-a-modeling-analysis
#9
Ann O'Leary, Elizabeth DiNenno, Amanda Honeycutt, Benjamin Allaire, Simon Neuwahl, Katherine Hicks, Stephanie Sansom
Anal intercourse is reported by many heterosexuals, and evidence suggests that its practice may be increasing. We estimated the proportion of the HIV burden attributable to anal sex in 2015 among heterosexual women and men in the United States. The HIV Optimization and Prevention Economics model was developed using parameter inputs from the literature for the sexually active U.S. population aged 13-64. The model uses differential equations to represent the progression of the population between compartments defined by HIV disease status and continuum-of-care stages from 2007 to 2015...
January 5, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28057144/-hiv-infection-and-associated-factors-in-men-who-have-sex-with-men-and-also-with-women-in-urumqi-from-2010-to-2014
#10
A J Cai, T Tian, Z Zhang, X L Zhao, Yekejiergeli Ye, Y Y Li, B X Huang, Ainiwaer Abidan, J H Dai
Objective: To understand the demographic characteristics, sexual behaviors and the factors associated with HIV infection in men who have sex with men and also with women (MSMW) in Urumqi. Methods: According to the "National AIDS Sentinel Surveillance Protocol" , the data of MSM's demographic characteristics, sex behavior histories and serological detection results were collected through Urumqi AIDS sentinel surveillance system during 2010-2014. In MSM, those also had heterosexual behaviors were considered as MSMW...
November 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28057143/-infection-status-of-hiv-in-men-who-have-sex-with-men-in-nanjing-2011-2015
#11
Y Y Xu, Z P Zhu, S S Wu, Z Q Pu, L Liu, L Guo, M Zhang
Objective: To understand the current status of HIV infection in men who have sex with men (MSM) in Nanjing, explore the associated factors with HIV infection, and provide information for the intervention in MSM. Methods: Data collected in the consecutive sentinel surveillances among MSM during 2011-2015 includes MSM's social-demographic information, sexual behavior histories, access to HIV prevention services and HIV testing in the past year. The infection trend was analyzed with χ(2) test and the factors associated with HIV infection were identified through multivariate logistic regression analysis...
November 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28050650/number-of-psychosocial-strengths-predicts-reduced-hiv-sexual-risk-behaviors-above-and-beyond-syndemic-problems-among-gay-and-bisexual-men
#12
Trevor A Hart, Syed W Noor, Barry D Adam, Julia R G Vernon, David J Brennan, Sandra Gardner, Winston Husbands, Ted Myers
Syndemics research shows the additive effect of psychosocial problems on high-risk sexual behavior among gay and bisexual men (GBM). Psychosocial strengths may predict less engagement in high-risk sexual behavior. In a study of 470 ethnically diverse HIV-negative GBM, regression models were computed using number of syndemic psychosocial problems, number of psychosocial strengths, and serodiscordant condomless anal sex (CAS). The number of syndemic psychosocial problems correlated with serodiscordant CAS (RR = 1...
January 3, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28039531/stress-and-psychopathology-and-its-impact-on-quality-of-life-in-chronic-anal-fissure-caf-patients
#13
Özden Arısoy, Neriman Şengül, Affan Çakir
BACKGROUND: Chronic anal fissure (CAF) onset, exacerbation, and impact on quality of life are influenced by a host of psychological, physiological, and social factors. We aimed to investigate the difference in psychopathology and stress between normal and CAF groups. METHODS: Thirty CAF patients and 20 age-sex matched healthy controls were evaluated for Axis I psychopathology, depression, anxiety, and stress with Hamilton and Hospital Depression-Anxiety Scales, Perceived Stress Scale, and SF-36...
December 30, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28031243/caenorhabditis-elegans-male-copulation-circuitry-incorporates-sex-shared-defecation-components-to-promote-intromission-and-sperm-transfer
#14
Brigitte LeBoeuf, L Rene Garcia
Sexual dimorphism can be achieved using a variety of mechanisms, including sex-specific circuits and sex-specific function of shared circuits, though how these work together to produce sexually dimorphic behaviors require further investigation. Here, we explore how components of the sex-shared defecation circuitry are incorporated into the sex-specific male mating circuitry in Caenorhabditis elegans to produce successful copulation. Using behavioral studies, calcium imaging, and genetic manipulation, we show that aspects of the defecation system are co-opted by the male copulatory circuitry to facilitate intromission and ejaculation...
December 27, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28027656/sexual-identity-and-behavior-in-an-online-sample-of-indian-men-who-have-sex-with-men
#15
Maria L Ekstrand, Shruta Rawat, Pallav Patankar, Elsa Heylen, Asha Banu, B R Simon Rosser, J Michael Wilkerson
Indian men who have sex with men are disproportionately impacted by HIV. While prevention efforts to date have focused on men who visit drop-in centers or physical cruising sites, little is known about men who are meeting sexual partners on virtual platforms. This paper explores issues related to sexual identity and sexual behaviors in an online sample of men who identified as gay (n = 279) or bisexual (n = 123). There were significant differences in outedness between the two groups, with 48% of bisexually identified men reporting that they were out to "no one" and 82% stating that they present themselves as heterosexual to family and friends...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/28027001/a-case-of-rectal-ureaplasma-infection-and-implications-for-testing-in-young-men-who-have-sex-with-men-the-p18-cohort-study
#16
Collette E Abbott, Richard E Greene, Farzana Kapadia, Perry N Halkitis
Ureaplasma is a significant cause of nongonococcal urethritis. This is a case of rectal Ureaplasma found on culture in a young man who has sex with men not previously reported in the literature. Nucleic acid amplification tests are now standard of care for sexually transmitted infection testing, but they do not test for Ureaplasma and, therefore, may be missing important infections. Ureaplasma could have important implications in urethritis and rectal HIV transmission among men who have sex with men engaging in condomless anal intercourse...
December 27, 2016: LGBT Health
https://www.readbyqxmd.com/read/28025737/substance-use-and-sexual-risk-behavior-among-black-south-african-men-who-have-sex-with-men-the-moderating-effects-of-reasons-for-drinking-and-safer-sex-intentions
#17
Justin Knox, Vasu Reddy, Tim Lane, Deborah Hasin, Theo Sandfort
Research studies suggest an association between substance use and sexual risk behavior, but are not completely consistent. The moderating effects of other psychosocial factors might help explain these inconsistencies. The current study therefore assessed whether substance use is associated with sexual risk behavior, and whether this relationship is modified by expectancies about the effects of alcohol, reasons for consuming alcohol, or intentions to engage in safe sex. A cross-sectional survey was conducted among 480 black South African men who have sex with men recruited using respondent-driven sampling...
December 26, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/28019101/subtypes-and-risk-behaviors-among-incident-hiv-cases-in-the-bangkok-men-who-have-sex-with-men-cohort-study-thailand-2006-2015
#18
Caitlin R Lam, Timothy H Holtz, Wanna Leelawiwat, Philip Mock, Wannee Chonwattana, Wipas Wimonsate, Anchalee Varangrat, Warunee Thienkrua, Charles Rose, Anupong Chitwarakorn, Marcel E Curlin
INTRODUCTION: HIV-1 incidence and prevalence remain high among men who have sex with men (MSM), and transgender women (TGW), in Thailand. To examine the link between epidemiologic factors and HIV-1 subtype transmission among Thai MSM, we compared covariates of infection with HIV CRF01-AE and other HIV strains among participants in the Bangkok MSM Cohort Study (BMCS). MATERIALS AND METHODS: The BMCS was an observational cohort study of Thai MSM and TGW with up to 60 months of follow-up at 4-monthly intervals...
December 24, 2016: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28013267/shedding-of-hepatitis-c-virus-into-the-rectum-of-hiv-infected-men-who-have-sex-with-men
#19
Andrew L Foster, Michael M Gaisa, Rosanne M Hijdra, Samuel S Turner, Tristan J Morey, Karen B Jacobson, Daniel S Fierer
BACKGROUND: For over a decade we have known of an epidemic of sexually transmitted hepatitis C virus (HCV) infection among human immunodeficiency virus (HIV)-infected men who have sex with men (MSM), but there still remains significant controversy over which bodily fluid(s) are responsible for HCV transmission in these men. METHODS: We enrolled HIV-infected MSM with recent and chronic HCV infection and quantified HCV from rectal fluid obtained by blind swab. We compared the rectal HCV viral load (VL) with paired blood HCV VL...
November 9, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28011978/what-is-the-best-tool-for-transanal-endoscopic-microsurgery-tem-a-case-matched-study-in-74-patients-comparing-a-standard-platform-and-a-disposable-material
#20
Diane Mege, Valérie Bridoux, Léon Maggiori, Jean-Jacques Tuech, Yves Panis
PURPOSE: Transanal endoscopic microsurgery (TEM) is the gold standard for local excision of rectal lesions, but no study exists concerning the best material. The objective was to compare TEM using a disposable material vs a standard platform through a case-matched study. METHODS: Patients who underwent TEM for rectal neoplasms were identified from prospective databases in two tertiary referral centers and matched according to four criteria (sex, tumor location, size, distance from the anal verge): TEM using a disposable material (GelPoint Applied®; group A) and TEM using a standard TEO® platform (Karl Storz, Tuttlingen, Germany; group B)...
December 24, 2016: International Journal of Colorectal Disease
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