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2016

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https://www.readbyqxmd.com/read/28806827/-functional-outcome-following-high-pressure-injection-injuries-of-the-hand
#1
Florian Neubrech, Christian A Radu, David Pauli, Berthold Bickert, Ulrich Kneser, Leila Harhaus
Background High-pressure injection injuries are devastating injuries that often lead to an amputation of the primarily affected finger. The available literature mainly focuses on amputation rates, while there is a lack of knowledge regarding functional results. Patients and Methods Between 1998 and 2016, 47 cases of high-pressure injection injuries of the hand were registered in our department. Out of these, data of 26 patients, all men with an average age of 42 (18-62) years, were included in a retrospective follow-up examination after 4 (1-12) years...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28806822/-multiple-myeloma-current-status-in-diagnostic-testing-and-therapy
#2
Michael Kehrer, Sebastian Koob, Andreas Strauss, Dieter Christian Wirtz, Jan Schmolders
Background Multiple myeloma is a haematological blood cancer of the bone marrow and is classified by the World Health Organisation (WHO) as a plasma cell neoplasm. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of an abnormal immunoglobulin called monoclonal protein or M protein. This ultimately causes multiple myeloma symptoms such as bone damage or kidney problems. The annual worldwide incidence of multiple myeloma is estimated to be 6 - 7/100,000 and accounts for 1% of all cancer...
August 14, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28806751/the-relative-age-effect-reversal-among-the-national-hockey-league-elite
#3
Luca Fumarco, Benjamin G Gibbs, Jonathan A Jarvis, Giambattista Rossi
Like many sports in adolescence, junior hockey is organized by age groups. Typically, players born after December 31st are placed in the subsequent age cohort and as a result, will have an age advantage over those players born closer to the end of the year. While this relative age effect (RAE) has been well-established in junior hockey and other professional sports, the long-term impact of this phenomenon is not well understood. Using roster data on North American National Hockey League (NHL) players from the 2008-2009 season to the 2015-2016 season, we document a RAE reversal-players born in the last quarter of the year (October-December) score more and command higher salaries than those born in the first quarter of the year...
2017: PloS One
https://www.readbyqxmd.com/read/28806618/public-sentiment-and-discourse-about-zika-virus-on-instagram
#4
E K Seltzer, E Horst-Martz, M Lu, R M Merchant
OBJECTIVE: Social media have strongly influenced the awareness and perceptions of public health emergencies, and a considerable amount of social media content is now shared through images, rather than text alone. This content can impact preparedness and response due to the popularity and real-time nature of social media platforms. We sought to explore how the image-sharing platform Instagram is used for information dissemination and conversation during the current Zika outbreak. STUDY DESIGN: This was a retrospective review of publicly posted images about Zika on Instagram...
August 11, 2017: Public Health
https://www.readbyqxmd.com/read/28806562/zika-virus-induced-neurological-critical-illness-in-latin-america-severe-guillain-barre-syndrome-and-encephalitis
#5
Sebastián U Ugarte, Angel Ricardo V Arenas, Bruno C Alvarez, Angela Cubides, Angélica F Luna, Max Arroyo-Parejo, Cayri E Acuña, Agamenón V Quintero, Orlando Ch Villareal, Oscar S Pinillos, Elías Vieda, Manuel Bello, Susana Peña, Carmelo Dueñas-Castell, Gloria M V Rodriguez, Jorge L M Ranero, Rosa L M López, Sandra G Olaya, José C Vergara, Ana Tandazo, Juan P S Ospina, Igor M Leyton Soto, R A Fowler, John C Marshall
Zika virus (ZIKAV) is classically described as causing minor symptoms in adult patients, however neurologic complications have been recognized. The recent outbreak in Central and South America has resulted in serious illness in some adult patients. We report adult patients in Latin America diagnosed with ZIKAV infection admitted to Intensive Care Units (ICUs). METHODS: Multicenter, prospective case series of adult patients with laboratory diagnosis of ZIKAV in 16 ICUs in 8 countries. RESULTS: Between December 1st 2015 and April 2nd 2016, 16 ICUs in 8 countries enrolled 49 critically ill patients with diagnosis of ZIKAV infection...
August 9, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28806479/zika-virus-disease-in-children-in-colombia-august-2015-to-may-2016
#6
Natalia Tolosa, Sarah C Tinker, Oscar Pacheco, Diana Valencia, Daniela Salas Botero, Van T Tong, Marcela Mercado, Suzanne M Gilboa, Maritza Gonzalez, Christina A Nelson, Lissethe Pardo, Carol Y Rao, Angélica Rico, Meredith Moore, Edgar Parra, Margaret A Honein, Martha L Ospina Martínez
BACKGROUND: Children are considered a potentially vulnerable population for Zika virus infection. However, data on paediatric Zika virus infection are sparse. METHODS: We analysed data from Colombia's national surveillance system during the 2015-2016 Zika virus outbreak on patients meeting the clinical case definition of Zika virus disease (ZVD) among children aged 1 month to 18 years to estimate incidence by demographic characteristics and characterize the occurrence of selected complications...
August 14, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28806470/efficacy-and-safety-of-sugammadex-versus-neostigmine-in-reversing-neuromuscular-blockade-in-adults
#7
REVIEW
Ana-Marija Hristovska, Patricia Duch, Mikkel Allingstrup, Arash Afshari
BACKGROUND: Acetylcholinesterase inhibitors, such as neostigmine, have traditionally been used for reversal of non-depolarizing neuromuscular blocking agents. However, these drugs have significant limitations, such as indirect mechanisms of reversal, limited and unpredictable efficacy, and undesirable autonomic responses. Sugammadex is a selective relaxant-binding agent specifically developed for rapid reversal of non-depolarizing neuromuscular blockade induced by rocuronium. Its potential clinical benefits include fast and predictable reversal of any degree of block, increased patient safety, reduced incidence of residual block on recovery, and more efficient use of healthcare resources...
August 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28806464/beyond-back-to-sleep-ways-to-further-reduce-the-risk-of-sudden-infant-death-syndrome
#8
Fern R Hauck, Kawai O Tanabe
Sudden infant death syndrome (SIDS) remains the leading cause of postneonatal mortality in the United States, despite reduction in rates of more than 50% since the initiation of the "Back to Sleep" (now called "Safe to Sleep") campaign in 1994. In recent years, the rate of decline in SIDS deaths has plateaued, even with the ongoing educational efforts that promote safe sleep and other risk reduction measures. The 2016 American Academy of Pediatrics guidelines for reducing the risk of SIDS focus heavily on sleep practices, bedding, and location, but also include factors that often receive less attention (ie, prenatal care, maternal smoking, alcohol and drug use, and childhood vaccinations)...
August 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28806453/neurologic-complications-associated-with-the-zika-virus-in-brazilian-adults
#9
Ivan Rocha Ferreira da Silva, Jennifer A Frontera, Ana Maria Bispo de Filippis, Osvaldo Jose Moreira do Nascimento
Importance: There are no prospective cohort studies assessing the incidence and spectrum of neurologic manifestations secondary to Zika virus (ZIKV) infection in adults. Objective: To evaluate the rates of acute ZIKV infection among patients hospitalized with Guillain-Barré syndrome (GBS), meningoencephalitis, or transverse myelitis. Design, Setting, and Participants: A prospective, observational cohort study was conducted at a tertiary referral center for neurological diseases in Rio de Janeiro, Brazil, between December 5, 2015, and May 10, 2016, among consecutive hospitalized adults (>18 years of age) with new-onset acute parainfectious or neuroinflammatory disease...
August 14, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28806445/use-of-laboratory-markers-in-addition-to-symptoms-for-diagnosis-of-inflammatory-bowel-disease-in-children-a-meta-analysis-of-individual-patient-data
#10
Gea A Holtman, Yvonne Lisman-van Leeuwen, Andrew S Day, Ulrika L Fagerberg, Paul Henderson, Stevan T Leach, Gøri Perminow, David Mack, Patrick F van Rheenen, Els van de Vijver, David C Wilson, Johannes B Reitsma, Marjolein Y Berger
Importance: Blood markers and fecal calprotectin are used in the diagnostic workup for inflammatory bowel disease (IBD) in pediatric patients. Any added diagnostic value of these laboratory markers remains unclear. Objective: To determine whether adding laboratory markers to evaluation of signs and symptoms improves accuracy when diagnosing pediatric IBD. Data Sources: A literature search of MEDLINE and EMBASE from inception through September 26, 2016...
August 14, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28806361/health-disparities-in-veterans-a-map-of-the-evidence
#11
Karli Kondo, Allison Low, Teresa Everson, Christine D Gordon, Stephanie Veazie, Crystal C Lozier, Michele Freeman, Makalapua Motu'apuaka, Aaron Mendelson, Mark Friesen, Robin Paynter, Caroline Friesen, Johanna Anderson, Erin Boundy, Somnath Saha, Ana Quiñones, Devan Kansagara
BACKGROUND: Goals for improving the quality of care for all Veterans and eliminating health disparities are outlined in the Veterans Health Administration Blueprint for Excellence, but the degree to which disparities in utilization, health outcomes, and quality of care affect Veterans is not well understood. OBJECTIVES: To characterize the research on health care disparities in the Veterans Health Administration by means of a map of the evidence. RESEARCH DESIGN: We conducted a systematic search for research studies published from 2006 to February 2016 in MEDLINE and other data sources...
September 2017: Medical Care
https://www.readbyqxmd.com/read/28806355/seroprevalence-of-anti-polio-antibodies-in-children-from-polio-high-risk-areas-of-pakistan-a-cross-sectional-survey-2015-2016
#12
Imtiaz Hussain, Ondrej Mach, Atif Habib, Zaid Bhatti, Zamir Suhag, M Steven Oberste, William C Weldon, Roland W Sutter, Sajid B Soofi, Zulfiqar A Bhutta
BACKGROUND: Pakistan is one of the 3 remaining wild poliovirus endemic countries. We collected sera from children to assess the prevalence of poliovirus antibodies in selected high-risk areas for poliovirus transmission. METHODS: Children in 2 age groups (6-11 and 36-48 months) were randomly selected between November 2015 and March 2016 in 6 areas of Pakistan (Sindh Province: Karachi and Kashmore; Khyber Pakhtunkhwa Province: Peshawar, Bannu and Nowshera; Punjab Province: Faisalabad)...
September 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28806352/association-between-exposure-to-noise-and-risk-of-hypertension-a-meta-analysis-of-observational-epidemiological-studies
#13
Wenning Fu, Chao Wang, Li Zou, Qiaoyan Liu, Yong Gan, Shijiao Yan, Fujian Song, Zhihong Wang, Zuxun Lu, Shiyi Cao
OBJECTIVE: An increasing amount of original studies suggested that exposure to noise could be associated with the risk of hypertension, but the results remain inconsistent and inconclusive. We aimed to synthesize available epidemiological evidence about the relationship between various types of noise and hypertension, and to explore the potential dose-response relationship between them in an up-to-date meta-analysis. METHODS: We conducted a literature search of PubMed and Embase from these databases' inception through December 2016 to identify observational epidemiological studies examining the association between noise and risk of hypertension...
August 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28806331/cochlear-implants-meet-regenerative-biology-state-of-the-science-and-future-research-directions
#14
Alain Dabdoub, Koji Nishimura
: The cochlear implant, the first device to restore a human sense, is an electronic substitute for lost mechanosensory hair cells. It has been successful at providing hearing to people with severe to profound hearing loss and as of 2012, an estimated 324,000 patients worldwide have received cochlear implants. Users of cochlear implants however, suffer from difficulties in processing complex sounds such as music and in discriminating sounds in noisy environments. Recent advances in regenerative biology and medicine are opening new avenues for enhancing the efficacy of cochlear implants by improving the neural interface in the future and offer the possibility of an entirely biological solution for hearing loss in the long term...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806329/physiological-mechanisms-in-combined-electric-acoustic-stimulation
#15
Mika Sato, Peter Baumhoff, Jochen Tillein, Andrej Kral
OBJECTIVE: Electrical stimulation is normally performed on ears that have no hearing function, i.e., lack functional hair cells. The properties of electrically-evoked responses in these cochleae were investigated in several previous studies. Recent clinical developments have introduced cochlear implantation (CI) in residually-hearing ears to improve speech understanding in noise. The present study documents the known physiological differences between electrical stimulation of hair cells and of spiral ganglion cells, respectively, and reviews the mechanisms of combined electric and acoustic stimulation in the hearing ears...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806328/introduction-to-the-14th-international-symposium-on-cochlear-implants-and-other-implantable-auditory-technologies-toronto-canada-may-11-to-14-2016
#16
Julian M Nedzelski, Joseph M Chen, Vincent Y W Lin, Alain Dabdoub
No abstract text is available yet for this article.
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806311/evaluation-of-maximal-speech-intelligibility-with-vibrant-soundbridge-in-patients-with-sensorineural-hearing-loss
#17
Hyun-Jin Lee, Jeon Mi Lee, Jae Young Choi, Jinsei Jung
OBJECTIVE: The study investigated improvements in maximal speech intelligibility after Vibrant Soundbridge (VSB) implantation and analyzed the effect of the hearing loss pattern on maximal speech intelligibility represented by a phonetically balanced word score (PBmax). The effect of middle ear implants on PBmax has not been evaluated yet. STUDY DESIGN: Study. SETTING: Tertiary academic medical center. PATIENTS/INTERVENTIONS: Sixty patients who underwent VSB from December 2011 to January 2016 were retrospectively reviewed...
August 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806309/single-center-experience-of-over-a-hundred-implantations-of-a-transcutaneous-bone-conduction-device
#18
Panagiotis A Dimitriadis, Daniel Hind, Kay Wright, Vicki Proctor, Larissa Greenwood, Suzanne Carrick, Jaydip Ray
OBJECTIVE: To assess outcomes with a novel passive transcutaneous bone conduction device (t-BCD). STUDY DESIGN: Prospective data collection and patient review. SETTING: Tertiary referral center. PATIENTS: Patients who underwent implantation with the t-BCD between November 2013 and September 2016. INTERVENTION: Implantation of BAHA Attract. MAIN OUTCOME MEASURES: Surgical outcome, patient reported outcomes including the "Glasgow Benefit Inventory" and the "Client Oriented Scale of Improvement" for adults and the "Speech, Spatial and Qualities of Hearing scale" (SSQ-12) for children...
August 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806293/-optimizing-your-post-surgical-scars-a-systematic-review-on-best-practices-in-preventative-scar-management-1
#19
Justin L Perez, Rod J Rohrich
BACKGROUND: Scar management is critical for every plastic surgeon's practice and, ultimately, the patient's satisfaction with his or her aesthetic result. Despite the critical nature of this component of routine post-operative care, there has yet to be a comprehensive analysis of the available literature over the last decade to assess the best algorithmic approach to scar care. To this end, a systematic review of best practices in preventative scar management was conducted to elucidate the highest level of evidence available on this subject to date...
August 3, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28806284/is-extracorporeal-cardiopulmonary-resuscitation-practical-in-severe-chest-trauma-a-systematic-review-in-single-center-of-developing-country
#20
Up Huh, Seunghwan Song, Sung Woon Chung, Sang-Pil Kim, Chung Won Lee, Hyo Young Ahn, Miju Bae, Seon Hee Kim
BACKGROUND: We report our experience with extracorporeal cardiopulmonary resuscitation (ECPR) in patients with rupture of heart and major vessels caused by severe chest trauma. METHODS: From April 2015 to May 2016, 10 patients with suspected injuries to the heart and major vessels following focused assessment with sonography in trauma or computed tomography were selected from patients admitted at a level I trauma centre presenting with cardiac tamponade and tension haemothorax due to severe chest trauma...
August 12, 2017: Journal of Trauma and Acute Care Surgery
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